N. Pham

M. Tsao, N. Pham, M. Johnston, 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Abstract B32: Retrospective correlative study between EGFRvIII, HPV, p16, c‐MET and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN)

M. Tsao, Lisa I. Wang, S. Kamel‐Reid, 2009 .

BAD Induces Apoptosis in Cells Over-Expressing Bcl-2 or Bcl-xL without Loss of Mitochondrial Membrane Potential

M. Minden, D. Hedley, N. Pham, 2001, Leukemia & lymphoma.

Simultaneous detection of mitochondrial respiratory chain activity and reactive oxygen in digitonin-permeabilized cells using flow cytometry.

D. Hedley, N. Pham, B. Robinson, 2000, Cytometry.

A comparative study of cytoplasmic granules imaged by the real-time microscope, Nile Red and Filipin in fibroblasts from patients with lipid storage diseases

N. Pham, J. Callahan, R. Bagshaw, 2005, Journal of Inherited Metabolic Disease.

Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes

M. Moran, M. Tsao, F. Shepherd, 2022, Nature Communications.

Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.

I. Jurisica, B. Neel, M. Tsao, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The Ability to Form Primary Tumor Xenografts Is Predictive of Increased Risk of Disease Recurrence in Early-Stage Non–Small Cell Lung Cancer

M. Tsao, F. Shepherd, N. Pham, 2010, Clinical Cancer Research.

Organoid Cultures as Preclinical Models of Non–Small Cell Lung Cancer

B. Haibe-Kains, M. Tsao, Ni Liu, 2019, Clinical Cancer Research.

Molecular heterogeneity of non‐small cell lung carcinoma patient‐derived xenografts closely reflect their primary tumors

J. McPherson, M. Moran, M. Starmans, 2017, International journal of cancer.

Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer

M. Moran, M. Tsao, F. Shepherd, 2019, Cancers.

Non-driver somatic alteration burden confers good prognosis in non-small cell lung cancer

M. Moran, M. Tsao, F. Shepherd, 2018, bioRxiv.

Optimizing Drug Response Study Design in Patient-Derived Tumor Xenografts

M. Tsao, F. Shepherd, N. Pham, 2022, Cancer informatics.

Targeting the CDK4/6-Rb Pathway Enhances Response to PI3K Inhibition in PIK3CA-Mutant Lung Squamous Cell Carcinoma

M. Tsao, F. Shepherd, N. Moghal, 2018, Clinical Cancer Research.

Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts

M. Tsao, N. Moghal, N. Pham, 2021, Translational oncology.

Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact

Paul Taylor, Michael F Moran, Yuhong Wei, 2014, Nature Communications.

Altered Mitochondrial Structure and Motion Dynamics in Living Cells with Energy Metabolism Defects Revealed by Real Time Microscope Imaging

N. Pham, B. Robinson, B. Chue, 2004, Microscopy and Microanalysis.

Oxidative stress is generated via the mitochondrial respiratory chain during plant cell apoptosis

D. Hedley, N. Pham, I. Weir, 2003, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Novel combinations of PI3K-mTOR inhibitors with dacomitinib or chemotherapy in PTEN-deficient patient-derived tumor xenografts

B. Clarke, B. Neel, M. Tsao, 2017, Oncotarget.

Lung Cancer Driven by BRAF Mutation Is Targetable by EGFR Kinase Inhibitors

M. Ikura, M. Tsao, Ni Liu, 2022 .

Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer

M. Moran, A. Caudy, T. Kislinger, 2022, Molecular cancer research : MCR.

SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis

Bo Ram Kim, M. Tsao, N. Moghal, 2016, PLoS biology.

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

I Jurisica, I. Jurisica, Y. Wang, 2015, Oncogene.

EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models.

M. Tsao, F. Shepherd, N. Moghal, 2020, Lung cancer.

The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.

D. Hedley, N. Pham, J. Jacobberger, 2004, Molecular cancer therapeutics.

A Multicenter Phase II Clinical Trial of Lapatinib (GW572016) in Hormonally Untreated Advanced Prostate Cancer

Joseph L. Chin, John Trachtenberg, Lisa Wang, 2010, American journal of clinical oncology.

MTE01.02 Lung Patient Derived Xenograft and Organoid

M. Moran, M. Tsao, F. Shepherd, 2018, Journal of Thoracic Oncology.

Cetuximab Inhibits T790M-Mediated Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in a Lung Adenocarcinoma Patient-Derived Xenograft Mouse Model.

M. Tsao, F. Shepherd, Geoffrey Liu, 2016, Clinical lung cancer.

Abstract B32: Fidelity of genomic and proteomic features of patient-derived xenografts of lung cancers

M. Moran, Lei Li, M. Tsao, 2016 .

Patient-derived tumor xenograft models established from samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration.

M. Tsao, G. da Cunha Santos, N. Pham, 2015, Lung cancer.

A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium

A. Tinker, A. Oza, B. Clarke, 2018, Clinical Cancer Research.

Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

Joerg Schwock, Ming-Sound Tsao, David W Hedley, 2008, BMC Cancer.

Phase I Combination of Sorafenib and Erlotinib Therapy in Solid Tumors: Safety, Pharmacokinetic, and Pharmacodynamic Evaluation from an Expansion Cohort

T. Mak, M. Tsao, B. Bandarchi-Chamkhaleh, 2010, Molecular Cancer Therapeutics.

An Anaplastic Lymphoma Kinase Immunohistochemistry–Negative but Fluorescence In Situ Hybridization–Positive Lung Adenocarcinoma Is Resistant to Crizotinib

T. Pugh, M. Tsao, M. Varella‐Garcia, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Assessing therapy response in patient-derived xenografts

A. Goldenberg, Ladislav Rampášek, Benjamin Haibe-Kains, 2021, Science Translational Medicine.

The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

M. Tsao, O. Ludkovski, S. Kamel‐Reid, 2011, Head & neck oncology.

The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2

M. Minden, T. Mak, D. Hedley, 2001, Cell Death and Differentiation.

CT Radiomics and Whole Genome Sequencing in Patients with Pancreatic Ductal Adenocarcinoma: Predictive Radiogenomics Modeling

M. Haider, P. Veit-Haibach, N. Pham, 2022, Cancers.

Cancer proteome and metabolite changes linked to SHMT2

M. Moran, C. Hawkins, M. Tsao, 2020, PloS one.

CD45+CD326+ Cells are Predictive of Poor Prognosis in Non–Small Cell Lung Cancer Patients

R. Yamashita, M. Nagasaki, M. Tsao, 2019, Clinical Cancer Research.

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus–Related Cervical Carcinoma

A. Tinker, H. Mackay, A. Oza, 2017, JAMA oncology.

Respiratory chain-generated oxidative stress following treatment of leukemic blasts with DNA-damaging agents.

D. Hedley, N. Pham, 2001, Experimental cell research.

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Nikolina Radulovich, Gennady Poda, Yannis Kalaidzidis, 2020, Nature Chemical Biology.

Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo

D. Hedley, N. Pham, M. Cao, 2008, Cancer Chemotherapy and Pharmacology.

A phase 1/2 study of ipilimumab in women with metastatic or recurrent HPV-related cervical carcinoma: A study of the Princess Margaret and Chicago N01 Consortia.

A. Tinker, H. Mackay, A. Oza, 2014 .

Lung cancer driven by BRAFG469V mutation is targetable by EGFR kinase inhibitors.

M. Ikura, M. Tsao, Ni Liu, 2021, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Single cell analysis reveals transcriptomic features of drug tolerant persisters and stromal adaptation in a patient-derived EGFR-mutated lung adenocarcinoma xenograft model.

M. Tsao, F. Shepherd, N. Moghal, 2022, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

GENOMIC CHARACTERIZATION OF CDKN2A ALTERATIONS IN MENINGIOMAS (TR)

Cynthia, A. Gramolini, J. Wunder, 2023 .

Quantitative image analysis of immunohistochemical stains using a CMYK color model

M. Tsao, D. Hedley, N. Pham, 2007, Diagnostic pathology.

The Ability to Form Primary Tumor Xenografts Is Predictive of Increased Risk of Disease Recurrence in Early-Stage Non–Small Cell Lung Cancer

M. Tsao, F. Shepherd, N. Pham, 2010, Clinical Cancer Research.

Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact

M. Moran, A. Ignatchenko, L. Muthuswamy, 2014, Nature Communications.

D. Hedley, N. Pham, J. Jacobberger, 2004, Molecular cancer therapeutics.

Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.

I. Jurisica, B. Neel, M. Tsao, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Integrated Omic Analysis of Lung Cancer Reveals Metabolism Proteome Signatures with Prognostic Impact

L. Muthuswamy, T. Kislinger, N. Pham, 2015 .