N. Qian

发表

Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development

Yuan Zhu, Hervé Broly, Andrew J Racher, 2018, PDA Journal of Pharmaceutical Science and Technology.

Hypoxia and transforming growth factor‐beta1 pathway activation promote Chinese Hamster Ovary cell aggregation

Michael C. Borys, M. Borys, Z. Li, 2018, Biotechnology and bioengineering.

LongR3 enhances Fc-fusion protein N-linked glycosylation while improving protein productivity in an industrial CHO cell line

Nicholas R. Abu-Absi, Michael C. Borys, A. Lewis, 2017 .

Hypoxia influences protein transport and epigenetic repression of CHO cell cultures in shake flasks.

Z. Li, N. Qian, Yueming Qian, 2014, Biotechnology journal.

WITHDRAWN: Aminoglycoside phosphotransferase II gene as primary selection marker for Pichia pastoris producing full-length monoclonal antibody.

Z. Li, N. Qian, Xuankuo Xu, 2012, Protein expression and purification.

RETRACTED ARTICLE: Simultaneous expression of antibody light and heavy chains in Pichia pastoris: improving retransformation outcome by linearizing vector at a different site

Z. Li, N. Qian, Xuankuo Xu, 2012, Applied Microbiology and Biotechnology.

Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study

N. Lewen, Z. Li, N. Qian, 2014 .

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells.

N. Qian, L. Heasley, G. Johnson, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Early identification of unusually clustered mutations and root causes in therapeutic antibody development.

Xuning Wang, S. Kirov, M. Borys, 2018, Biotechnology and bioengineering.

Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.

N. Qian, G. Johnson, A. Gardner, 1993, The Journal of biological chemistry.

Expression of GTPase-deficient G alpha 16 inhibits Swiss 3T3 cell growth.

N. Qian, G. Johnson, G. Johnson, 1994, The Journal of biological chemistry.

How does the G protein, Gi2, transduce mitogenic signals?

N. Qian, G. Johnson, C. Lange-Carter, 1994, Journal of cellular biochemistry.

Distinct Role of ZAP-70 and Src Homology 2 Domain-Containing Leukocyte Protein of 76 kDa in the Prolonged Activation of Extracellular Signal-Regulated Protein Kinase by the Stromal Cell-Derived Factor-1α/CXCL12 Chemokine1

N. Qian, Ashok Kumar, K. Hedin, 2003, The Journal of Immunology.

Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation.

N. Qian, L. Heasley, R. Nemenoff, 1994, The Journal of biological chemistry.

Differential Modulation of Bombesin-stimulated Phospholipase Cβ and Mitogen-activated Protein Kinase Activity by [D-Arg1, D-Phe5, D-Trp7,9,Leu11>]Substance P (*)

N. Qian, L. Heasley, G. Johnson, 1995, The Journal of Biological Chemistry.

Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine receptor.

N. Qian, G. Johnson, S. Winitz, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Stromal Cell-Derived Factor-1 Signaling via the CXCR4-TCR Heterodimer Requires Phospholipase C-β3 and Phospholipase C-γ1 for Distinct Cellular Responses

Ian C. Clift, N. Qian, K. Hedin, 2011, The Journal of Immunology.

Phospholipase C-the CXCR 4-TCR Heterodimer Requires Stromal Cell-Derived Factor-1 Signaling via

Ian C. Clift, N. Qian, K. Hedin, 2011 .

Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.

G L Johnson, N. Qian, L. Heasley, 1993, The Journal of biological chemistry.

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells

Aiqing He, Zizhuo Xing, Z. Li, 2011, Biotechnology progress.

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning

Michael C. Borys, M. Borys, Z. Li, 2022, Bioengineering.

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and Rat la cells

N. Qian, G. Johnson, C. Gallego, 2022 .

Acetylcholine muscarinic receptor regulation of the Ras/Raf/MAP kinase pathway.

N. Qian, G. Johnson, M. Russell, 1995, Life sciences.

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media

Xuankuo Xu, Jianlin Xu, Zheng Jian Li, 2018, mAbs.

Expression of the mammalian system A neutral amino acid transporter in Xenopus oocytes.

R. Tarnuzzer, M. Campa, N. Qian, 1990, The Journal of biological chemistry.

Evidence for coordinate regulation of the A system for amino acid transport and the mRNA for the alpha 1 subunit of the Na+,K(+)-ATPase gene in Chinese hamster ovary cells.

N. Qian, M. Pastor-Anglada, E. Englesberg, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines

Michael C. Borys, N. Araníbar, B. Warrack, 2020, Engineering in life sciences.

RETRACTED ARTICLE: Simultaneous expression of antibody light and heavy chains in Pichia pastoris: improving retransformation outcome by linearizing vector at a different site

Z. Li, N. Qian, Xuankuo Xu, 2012, Applied Microbiology and Biotechnology.

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells

Z. Li, N. Qian, Yueming Qian, 2011, Biotechnology progress.