D. Umetsu

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Phosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthma.

M. Bruss, S. Jin, S. Goya, 2010, The Journal of allergy and clinical immunology.

Effectiveness of a multicomponent self-management program in at-risk, school-aged children with asthma.

T. Robinson, P. Sharek, D. Umetsu, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Recurrent sinopulmonary infection and impaired antibody response to bacterial capsular polysaccharide antigen in children with selective IgG-subclass deficiency.

R. Geha, D. Umetsu, G. Siber, 1985, The New England journal of medicine.

Development of Allergic Lung Inflammation in Resident Lung Cells Is Required for the TNF Receptor-Associated Factor 1 Expressed

S. Goya, D. Umetsu, M. Pichavant, 2008 .

TNF Receptor-Associated Factor 1 Expressed in Resident Lung Cells Is Required for the Development of Allergic Lung Inflammation1

S. Goya, D. Umetsu, M. Pichavant, 2008, The Journal of Immunology.

Recurrent sinopulmonary infection and impaired antibody response to bacterial capsular polysaccharide antigen in children with selective IgG-subclass deficiency.

R. Geha, D. Umetsu, G. Siber, 1986, The New England journal of medicine.

Selective defect in the antibody response to Haemophilus influenzae type b in children with recurrent infections and normal serum IgG subclass levels.

P. Schur, D. Umetsu, G. Siber, 1988, The Journal of allergy and clinical immunology.

Agreement among measures of asthma status: a prospective study of low-income children with moderate to severe asthma.

T. Robinson, P. Sharek, D. Umetsu, 2002, Pediatrics.

Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy.

E. Mignot, C. Kushida, D. Umetsu, 2003, Sleep.

A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans.

G. Freeman, S. Rosenzweig, D. Umetsu, 2011, The Journal of clinical investigation.

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Microbes, apoptosis and TIM‐1 in the development of asthma

D. Umetsu, R. DeKruyff, D. T. Umetsu, 2010, Clinical and experimental immunology.

Hepatitis A virus, TIM-1 and allergy

D. Umetsu, R. DeKruyff, 2009 .

TIM gene family and their role in atopic diseases.

G. Freeman, D. Umetsu, S. Umetsu, 2008, Current topics in microbiology and immunology.

Respiratory Tolerance Is Inhibited by the Administration of Corticosteroids1

D. Umetsu, P. Stock, O. Akbari, 2005, The Journal of Immunology.

Regulation of Tolerance in the Respiratory Tract: TIM‐1, Hygiene, and the Environment

D. Umetsu, R. DeKruyff, DALE T. UMETSU, 2004, Annals of the New York Academy of Sciences.

Role of regulatory T cells in allergy and asthma.

D. Umetsu, P. Stock, O. Akbari, 2003, Current opinion in immunology.

Regulatory T cells control the development of allergic disease and asthma.

D. Umetsu, O. Akbari, R. DeKruyff, 2003, Journal of Allergy and Clinical Immunology.

TIM-1, a novel allergy and asthma susceptibility gene

D. Umetsu, R. DeKruyff, J. McIntire, 2004, Springer Seminars in Immunopathology.

Hepatitis A virus link to atopic disease

N. Risch, P. Underhill, L. Cavalli-Sforza, 2003 .

TH1 and TH2 CD4+ cells in human allergic diseases.

D. Umetsu, R. DeKruyff, 1997, The Journal of allergy and clinical immunology.

The TIM gene family: emerging roles in immunity and disease

G. Freeman, V. Kuchroo, D. Umetsu, 2003, Nature Reviews Immunology.

Asthma: an epidemic of dysregulated immunity

D. Umetsu, O. Akbari, C. Macaubas, 2002, Nature Immunology.

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

Loise M. Francisco, G. Freeman, A. Sharpe, 2014, The Journal of experimental medicine.

Oral immunotherapy and anti-IgE antibody-adjunctive treatment for food allergy.

K. Nadeau, D. Umetsu, A. Kohli, 2012, Immunology and allergy clinics of North America.

Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy.

K. Nadeau, D. Umetsu, L. Hoyte, 2011, The Journal of allergy and clinical immunology.

Immunologic Effects of Omalizumab in Children with Severe Refractory Atopic Dermatitis: A Randomized, Placebo-Controlled Clinical Trial

K. Nadeau, D. Umetsu, E. Hoyte, 2013, International Archives of Allergy and Immunology.

Components Essential for the Generation of Germinal Centers

D. Umetsu, E. Secord, G. Thorbecke, 1998, Developmental immunology.

Genotype, phenotype, and outcomes of nine patients with T‐B+NK+ SCID

J. Puck, K. Nadeau, E. Stiehm, 2011, Pediatric transplantation.

Pulmonary Atypical Mycobacterial Infection in a Child with Severe Combined Immune Deficiency

D. Umetsu, R. Shames, M. Cowan, 1999 .

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.

R. Geha, S. Goya, D. Umetsu, 2009, The Journal of allergy and clinical immunology.

Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like–1 Resulting in Airway Hyperreactivity

G. Freeman, S. Goya, D. Umetsu, 2010, The Journal of Immunology.

Apoptotic Cells Activate NKT Cells through

G. Freeman, S. Goya, D. Umetsu, 2010 .

The role of type 2 innate lymphoid cells in asthma

D. Umetsu, R. DeKruyff, Ya‐Jen Chang, 2013, Journal of leukocyte biology.

Vaccine-Induced Antibody Isotypes Are Skewed by Impaired CD4 T Cell and Invariant NKT Cell Effector Responses in MyD88-Deficient Mice1

D. Umetsu, D. Nguyen, C. Nagler, 2009, The Journal of Immunology.

Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production.

D. Umetsu, R. DeKruyff, Y. Fang, 1998, Journal of immunology.

CD1d restricted natural killer T cells are not required for allergic skin inflammation.

R. Geha, S. Goya, D. Umetsu, 2006, The Journal of allergy and clinical immunology.

Regulation of the interaction between Th1 and Th2 T cell clones to provide help for antibody production in vivo

D. Umetsu, R. Caspi, L. Rizzo, 1995, European journal of immunology.

IL-4-based helper activity of CD4+ T cells is radiation sensitive.

D. Umetsu, R. DeKruyff, Y. Fang, 1995, Cellular immunology.

Differential regulation of antigen presentation in high‐ and low‐IgE responder mice

D. Umetsu, L. Rizzo, R. DeKruyff, 1991, European journal of immunology.

Induction of antibody synthesis by CD4+ T cells: IL 5 is essential for induction of antigen‐specific antibody responses by TH2 but not TH1 clones

D. Umetsu, R. DeKruyff, Rim R. Mosmann, 1990, European journal of immunology.

Induction of human IgE synthesis by CD4+ T cell clones. Requirement for interleukin 4 and low molecular weight B cell growth factor

D. Umetsu, J. Abrams, M. Palladino, 1989, The Journal of experimental medicine.

Adiponectin-Deficient Mice: Role of IL-17A Subacute Ozone Is Augmented in Pulmonary Inflammation Induced by

D. Umetsu, C. Hug, J. Tran, 2012 .

Pulmonary Inflammation Induced by Subacute Ozone Is Augmented in Adiponectin-Deficient Mice: Role of IL-17A

D. Umetsu, C. Hug, S. Shore, 2012, The Journal of Immunology.

iNKT cells in allergic disease.

D. Umetsu, E. Meyer, R. DeKruyff, 2007, Current topics in microbiology and immunology.

T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

G. Freeman, D. Umetsu, Hyun-Hee Lee, 2010, The Journal of Immunology.

T helper 2-dominant antilymphoma immune response is associated with fatal outcome.

D. Umetsu, N. Chao, Y. Chen, 1997, Blood.

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

D. Umetsu, M. Kronenberg, M. Taniguchi, 2003, Nature Medicine.

Animal Models of Airway Sensitization

E. Gelfand, S. Goya, D. Umetsu, 1999, Current protocols in immunology.

pneumonia function and enhances host defense in neutropenia-associated Targeted deletion of tumor suppressor PTEN augments neutrophil

Bryanne E. Robson, D. Umetsu, Yonghui Jia, 2014 .

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia.

Bryanne E. Robson, D. Umetsu, K. Ye, 2009, Blood.

High copy number I-Ab transgenes induce production of IgE through an interluekin 4-dependent mechanism.

H. Mcdevitt, D. Umetsu, S. Singer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Ligation of TAPA‐1 (CD81) or major histocompatibility complex class II in co‐cultures of human B and T lymphocytes enhances interleukin‐4 synthesis by antigen‐specific CD4+ T cells

S. Levy, D. Umetsu, R. DeKruyff, 1996, European journal of immunology.

Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells.

J. Lamb, D. Umetsu, R. DeKruyff, 1999, Journal of immunology.

TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation

V. Kuchroo, T. Strom, Z. Illés, 2005, Nature Immunology.

Role of regulatory dendritic cells in allergy and asthma

D. Umetsu, O. Akbari, 2004, Current allergy and asthma reports.

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity

D. Umetsu, P. Savage, M. Pichavant, 2013, Nature Medicine.

A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease

D. Umetsu, P. Savage, M. Pichavant, 2013, Nature medicine.

Early exposure to germs and the Hygiene Hypothesis

D. Umetsu, 2012, Cell Research.

T cells and NKT cells in the pathogenesis of asthma.

D. Umetsu, E. Meyer, R. DeKruyff, 2008, Annual review of medicine.

Induction of T helper type 1–like regulatory cells that express Foxp3 and protect against airway hyper-reactivity

G. Berry, G. Freeman, D. Umetsu, 2004, Nature Immunology.

Accessory cell requirements for lymphoma growth in vitro and in irradiated mice.

D. Umetsu, G. Thorbecke, S. Lerman, 1979, Cellular immunology.

Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivity.

T. Chatila, D. Umetsu, M. Noval Rivas, 2014, The Journal of allergy and clinical immunology.

Requirements for activation of human peripheral blood T cells by mouse monoclonal antibodies to CD3.

R. Geha, T. Chatila, D. Umetsu, 1987, Clinical immunology and immunopathology.

PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions

G. Freeman, A. Sharpe, D. Umetsu, 2010, Mucosal Immunology.

Homeostatic Survival Invariant NKT Cell Function and + CD4ICOS/ICOSL Interaction Is Required for

G. Freeman, A. Sharpe, D. Umetsu, 2008 .

ICOS/ICOSL Interaction Is Required for CD4+ Invariant NKT Cell Function and Homeostatic Survival1

G. Freeman, A. Sharpe, D. Umetsu, 2008, The Journal of Immunology.

Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40.

D. Umetsu, R. DeKruyff, R. Gieni, 1997, Journal of immunology.

Recognition by a human alloreactive T-cell clone of an HLA-DP-associated epitope on monocytes and fibroblasts but not on B cells

R. Geha, D. Umetsu, P. Hauschka, 1988, Journal of Clinical Immunology.

Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones.

W. Fiers, R. Geha, J. Pober, 1985, The Journal of clinical investigation.

Natural Killer T Cells Regulate the Development of Asthma

D. Umetsu, E. Meyer, R. DeKruyff, 2007, International reviews of immunology.

Heat-killed Listeria monocytogenes as an adjuvant converts established murine Th2-dominated immune responses into Th1-dominated responses.

D. Umetsu, R. DeKruyff, R. Gieni, 1998, Journal of immunology.

Interleukin-10: The missing link in asthma regulation?

D. Umetsu, R. DeKruyff, 1999, American journal of respiratory cell and molecular biology.

TIM-1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death

Paul, G. Freeman, D. Umetsu, 2013 .

Vaccination with Heat-Killed Listeria as Adjuvant Reverses Established Allergen-Induced Airway Hyperreactivity and Inflammation: Role of CD8+ T Cells and IL-181

G. Berry, D. Umetsu, R. DeKruyff, 2000, The Journal of Immunology.

Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation.

G. Berry, D. Umetsu, R. DeKruyff, 1999, The Journal of clinical investigation.

CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.

G. Berry, D. Umetsu, M. Kronenberg, 2006, The New England journal of medicine.

Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells.

G. Berry, S. Goya, D. Umetsu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

IL-18 Gene Transfer by Adenovirus Prevents the Development of and Reverses Established Allergen-Induced Airway Hyperreactivity1

G. Berry, S. Levy, D. Umetsu, 2001, The Journal of Immunology.

Flu strikes the hygiene hypothesis

D. Umetsu, 2004, Nature Medicine.

Allergen-Specific MHC Class II Tetramer+ Cells Are Detectable in Allergic, but Not in Nonallergic, Individuals1

D. Umetsu, G. Sønderstrup, W. Kwok, 2006, The Journal of Immunology.

Allergen-Specific MHC Class II Tetramer

D. Umetsu, G. Sønderstrup, T. Forsthuber, 2006 .

Nonallergic , Individuals Cells Are Detectable in Allergic , but Not in + Allergen-Specific MHC Class II Tetramer

D. Umetsu, G. Sønderstrup, W. Kwok, 2006 .

Myocardial specific creatine phosphokinase isoenzyme elevation in children with asthma treated with intravenous isoproterenol.

R. Geha, D. Umetsu, J. Maguire, 1986, The Journal of allergy and clinical immunology.

An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production.

S. Levy, H. Maecker, D. Umetsu, 1997, Journal of immunology.

A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients.

E. Blood, D. Umetsu, L. Schneider, 2013, The Journal of allergy and clinical immunology.

The safety and efficacy of ALLERVAX CAT in cat allergic patients.

D. Umetsu, D. Aaronson, C. Nicodemus, 1999, Clinical immunology.

Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes.

D. Umetsu, R. DeKruyff, M. Blotta, 1997, Journal of immunology.

Critical role of B cells in the development of T cell tolerance to aeroallergens.

D. Umetsu, R. DeKruyff, D. Tsitoura, 2002, International immunology.

Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity.

S. Akira, G. Besra, D. Umetsu, 2011, The Journal of clinical investigation.

Induction of immunoglobulin synthesis by CD4+ T cell clones.

D. Umetsu, L. Rizzo, R. DeKruyff, 1993, Seminars in immunology.

CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation.

G. Berry, D. Umetsu, Jae-Won Oh, 2002, The Journal of allergy and clinical immunology.

Natural killer T cells are important in the pathogenesis of asthma: the many pathways to asthma.

D. Umetsu, R. DeKruyff, 2010, The Journal of allergy and clinical immunology.

Functional heterogeneity among human inducer T cell clones.

R. Geha, D. Umetsu, A. Abbas, 1988, Journal of immunology.

CD8+ T cells regulate immune responses in a murine model of allergen‐induced sensitization and airway inflammation

U. Wahn, D. Umetsu, E. Hamelmann, 2004, European journal of immunology.

Respiratory Infection with Influenza A Virus Interferes with the Induction of Tolerance to Aeroallergens1

K. Dabbagh, D. Lewis, D. Umetsu, 2000, The Journal of Immunology.

Immunoglobulin A (IgA) Is a Natural Ligand of Hepatitis A Virus Cellular Receptor 1 (HAVCR1), and the Association of IgA with HAVCR1 Enhances Virus-Receptor Interactions

G. Freeman, D. Umetsu, C. Tami, 2007, Journal of Virology.

The kinetics of change in cytokine production by CD4 T cells during conventional allergen immunotherapy.

D. Umetsu, S. Benjaponpitak, V. Marinkovich, 1999, The Journal of allergy and clinical immunology.

Human alveolar macrophages induce functional inactivation in antigen-specific CD4 T cells.

D. Umetsu, R. Blumenthal, R. DeKruyff, 2001, The Journal of allergy and clinical immunology.

Restricted lymphokine synthesis in CD4+ Helper T cells : new insights into the regulation of IgE synthesis and the pathogenesis of allergic disease

D. Umetsu, R. DeKruyff, R. Bocian, 1992 .

Immune Homeostasis of the Lung: The Role of Regulatory NKT Cells in Asthma

D. Umetsu, R. DeKruyff, Ya‐Jen Chang, 2012 .

Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals.

D. Umetsu, E. Hoyte, J. McIntire, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis.

D. Umetsu, R. DeKruyff, M. Blotta, 1996, Journal of immunology.

TIM family of genes in immunity and tolerance.

V. Kuchroo, D. Umetsu, R. DeKruyff, 2006, Advances in immunology.

Immunotherapy for Allergic Diseases

D. Umetsu, R. DeKruyff, 2001 .

Allergen immunotherapy: novel approaches in the management of allergic diseases and asthma.

D. Umetsu, D. Campbell, R. DeKruyff, 2000, Clinical immunology.

Allergen-Induced Airway Hyperreactivity Adjuvant Reverses Established as Listeria Vaccination with Heat-Killed Umetsu

G. Berry, D. Umetsu, R. DeKruyff, 1999 .

Novel Genetic Regulation of T Helper 1 (Th1)/Th2 Cytokine Production and Encephalitogenicity in Inbred Mouse Strains

D. Umetsu, Z. Cao, I. Conboy, 1997, The Journal of experimental medicine.

Thl and Th2 CD4+ Cells in the Pathogenesis of Allergic Diseases (44109)

D. Umetsu, R. DeKruyff, 1997 .

Differential requirements of B cells from normal and allergic subjects for the induction of IgE synthesis by an alloreactive T cell clone

D. Umetsu, D. Leung, H. Jabara, 1985, The Journal of experimental medicine.

Aeroallergenswith the Induction of Tolerance to Respiratory Infection with Influenza A Virus

David Bruce Lewis, K. Dabbagh, D. Umetsu, 2013 .

NKT cells regulate the development of asthma

D. Umetsu, M. Kronenberg, M. Taniguchi, 2005 .

Editorial overview: novel concepts in the pathogenesis and therapy of allergy and asthma

D. Umetsu, R. DeKruyff, Dale T. Umetsu, 2004, Springer Seminars in Immunopathology.

Immunotherapy of asthma and allergic diseases

D. Umetsu, E. C. Tepas, Elizabeth C. TePas, 2000, Current opinion in pediatrics.

Current Perspectives: focused commentary: Key cells in asthma

D. Umetsu, R. DeKruyff, 2010 .

Allergen-Induced Airway Hyperreactivity Critical Role for IL-13 in the Development of

G. Berry, D. Umetsu, D. Donaldson, 2001 .

Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type

D. Umetsu, R. DeKruyff, H. Secrist, 1995, The Journal of experimental medicine.

In vitro synthesis of IL-4 by human CD4+ T cells requires repeated antigenic stimulation.

D. Umetsu, J. Abrams, Y. Wen, 1993, Cellular immunology.

This information is current as of Apoptotic Cells Phosphatidylserine and Mediate Phagocytosis Allelic Variants Differentially Recognize T Cell / Transmembrane , Ig , and Mucin-3

G. Freeman, D. Umetsu, J. Casasnovas, 2010 .

A role for natural killer T cells in asthma

D. Umetsu, R. DeKruyff, 2006, Nature Reviews Immunology.

Oral immunotherapy with omalizumab reverses the Th2 cell‐like programme of regulatory T cells and restores their function

T. Chatila, D. Umetsu, L. Schneider, 2018, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules.

G. Freeman, D. Umetsu, R. DeKruyff, 1995, The Journal of clinical investigation.

Tim‐1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells

V. Kuchroo, Hulin Jin, S. Xiao, 2011, European journal of immunology.

Respiratory tolerance in the protection against asthma.

D. Umetsu, C. Macaubas, R. DeKruyff, 2003, Current drug targets. Inflammation and allergy.

Airway Hyperreactivity 1 Resulting in - T Cell Ig-Like Mucin-Like Apoptotic Cells Activate NKT Cells through

G. Freeman, S. Goya, D. Umetsu, 2010 .

HSV : herpes simplex virus Reactivation : HSV DNA in sensory ganglia neurons directs synthesis of mRNA molecules that encode proteins required for HSV DNA replication and assembly of daughter virions

A. Ventura, S. Merajver, M. Shew, 2013 .

TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells

G. Freeman, D. Umetsu, N. Baumgarth, 2010, The Journal of Immunology.

This information is current as the Removal of Antigen-Specific T Cells Controls Adaptive Immunity by Regulating TIM-4 , a Receptor for Phosphatidylserine

G. Freeman, D. Umetsu, N. Baumgarth, 2010 .

Allergen-Induced Airway Hyperreactivity Is Diminished in CD81-Deficient Mice1

S. Levy, D. Umetsu, Jun Deng, 2000, The Journal of Immunology.

Diminished in CD 81-Deficient Mice Allergen-Induced Airway Hyperreactivity Is

S. Levy, D. Umetsu, Jun Deng, 2000 .

MyD88-Deficient Mice Invariant NKT Cell Effector Responses in Skewed by Impaired CD4 T Cell and Vaccine-Induced Antibody Isotypes Are

D. Umetsu, D. Nguyen, S. Behar, 2009 .

Presentation via Class II MHC Vaccination: Dependence on Antigen Cytotoxic T Cell Responses to DNA

S. Levy, H. Maecker, D. Umetsu, 2013 .

The costimulatory role of TIM molecules

V. Kuchroo, D. Umetsu, R. DeKruyff, 2009, Immunological reviews.

Anaphylactic reactions associated with omalizumab administration: Analysis of a case-control study.

P. Lieberman, D. Umetsu, G. Carrigan, 2016, The Journal of allergy and clinical immunology.

Generation of B cell memory and affinity maturation. Induction with Th1 and Th2 T cell clones.

D. Umetsu, L. Rizzo, R. DeKruyff, 1992, Journal of immunology.

Immunological mechanisms for desensitization and tolerance in food allergy

D. Umetsu, R. Rachid, 2012, Seminars in Immunopathology.

CD 1 d-Restricted NKT Cells in T-bet-Deficient Mice Requires The Development of Airway Hyperreactivity

D. Umetsu, P. Savage, M. Pichavant, 2009 .

iNKT Cells Require CCR4 to Localize to the Airways and to Induce Airway Hyperreactivity1

James J. Campbell, E. Butcher, D. Umetsu, 2007, The Journal of Immunology.

Signal 1 and Requires Costimulation to Tim-1 Signaling Substitutes for Conventional

V. Kuchroo, T. Strom, D. Umetsu, 2009 .

TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.

S. Nakae, D. Umetsu, H. Suto, 2007, Blood.

TIM-1 induces T cell activation and inhibits the development of peripheral tolerance

G. Berry, G. Freeman, D. Umetsu, 2005, Nature Immunology.

Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies.

K. Nadeau, D. Umetsu, H. Oettgen, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Anaphylaxis associated with omalizumab administration: Risk factors and patient characteristics.

P. Lieberman, D. Umetsu, R. Rajwanshi, 2017, The Journal of allergy and clinical immunology.

Production Lymphocytes by Inhibiting IL-12 + in CD4 Macrophages to Induce Th2 Cytokine Synthesis Corticosteroids Enhance the Capacity of

D. Umetsu, R. DeKruyff, Yu-song Fang, 1998 .

Vaccination with Allergen-IL-18 Fusion DNA Protects Against, and Reverses Established, Airway Hyperreactivity in a Murine Asthma Model1

S. Levy, H. Maecker, D. Umetsu, 2001, The Journal of Immunology.

In vitro production of antibody in cultures of human peripheral blood lymphocytes.

R. Geha, D. Umetsu, 1987, Methods in enzymology.

Pregnancy Outcomes in the Omalizumab Pregnancy Registry and a Disease-matched Comparator Cohort.

M. Cabana, E. Andrews, E. Andrews, 2020, The Journal of allergy and clinical immunology.

-Microglobulin-Deficient Mice 2 b in NK T Cells Induces Airway Hyperreactivity Activation of Nonclassical CD1d-Restricted

D. Umetsu, P. Savage, E. Meyer, 2008 .

Ly1- (CD5-) B cells produce interleukin (IL)-10.

D. Umetsu, R. DeKruyff, R. Gieni, 1997, Cellular immunology.

IL-12 inhibits the production of IL-4 and IL-10 in allergen-specific human CD4+ T lymphocytes.

D. Umetsu, S. Wolf, R. DeKruyff, 1995, Journal of immunology.

Revising the immunological theories of asthma and allergy

D. Umetsu, 2005, The Lancet.

Mechanisms preventing allergen-induced airways hyperreactivity: role of tolerance and immune deviation.

G. Berry, D. Umetsu, R. Blumenthal, 2000, The Journal of allergy and clinical immunology.

Antigen-primed T cells from B cell-deficient JHD mice fail to provide B cell help.

D. Umetsu, R. DeKruyff, A. Macaulay, 1998, Journal of immunology.

Hyperreactivityand to Induce Airway iNKT Cells Require CCR4 to Localize to the

E. Butcher, D. Umetsu, P. Savage, 2017 .

Hyperreactivity Airways and to Induce Airway iNKT Cells Require CCR 4 to Localize to the Campbell and

James J. Campbell, E. Butcher, D. Umetsu, 2007 .

Serum sickness triggered by anaphylaxis: a complication of immunotherapy.

J. Hahn, R. Geha, J. Hahn, 1985, The Journal of allergy and clinical immunology.

Analysis of antigen uptake and presentation by Epstein‐Barr virus‐transformed human lymphoblastoid B cells

R. Geha, D. Umetsu, E. Schneeberger, 1984, European journal of immunology.

Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses.

G. Freeman, S. Levy, D. Umetsu, 2002, International immunology.

Antigen-specific B cells preferentially induce CD4+ T cells to produce IL-4.

D. Umetsu, C. Goodnow, R. DeKruyff, 1997, Journal of immunology.

Synthesis of fungal glycolipid asperamide B and investigation of its ability to stimulate natural killer T cells.

D. Umetsu, P. Savage, L. Albacker, 2013, Organic letters.

hypomorphic RAG mutations Lack of iNKT cells in patients with combined immune deficiency due to

L. Notarangelo, S. Giliani, D. Umetsu, 2013 .

Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates.

Carrie A. Hendricks, D. Umetsu, P. Savage, 2008, The Journal of allergy and clinical immunology.

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals

D. Umetsu, H. Secrist, Y. Wen, 1993, The Journal of experimental medicine.

IL-4 synthesis byin vivo-primed memory CD4+ T Cells: II. Presence of IL-4 is not required for IL-4 synthesis in primed CD4+ T Cells

D. Umetsu, Yuni Fang, R. DeKruyff, 1995, Journal of Clinical Immunology.

Th 2-Dominated Immune Responses into Adjuvant Converts Established Murine as an Listeria monocytogenes Heat-Killed

D. Umetsu, R. DeKruyff, R. Gieni, 1998 .

IL-4 synthesis by in vivo primed keyhole limpet hemocyanin-specific CD4+ T cells. I. Influence of antigen concentration and antigen-presenting cell type.

D. Umetsu, R. DeKruyff, Y. Fang, 1992, Journal of immunology.

Tim-1 Signaling Substitutes for Conventional Signal 1 and Requires Costimulation to Induce T Cell Proliferation1

V. Kuchroo, T. Strom, D. Umetsu, 2009, The Journal of Immunology.

Food , drug , insect sting allergy , and anaphylaxis Omalizumab facilitates rapid oral desensitization for peanut allergy

K. Nadeau, D. Umetsu, L. Schneider, 2017 .

Oral immunotherapy and anti-IgE antibody treatment for food allergy

D. Umetsu, L. Schneider, R. Rachid, 2015, The World Allergy Organization journal.

Effects of IL‐12 in Memory CD4+ T Lymphocyte Responses a

D. Umetsu, R. DeKruyff, R. Gieni, 1996, Annals of the New York Academy of Sciences.

Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency.

D. Umetsu, F. Arredondo-Vega, M. Hershfield, 1994, American journal of human genetics.

T Cells by Functionally Disabled CD4 Induces Immunological Tolerance Mediated Intranasal Exposure to Protein Antigen

J. Lamb, D. Umetsu, R. DeKruyff, 1999 .

DNA vaccination with cytokine fusion constructs biases the immune response to ovalbumin.

S. Levy, H. Maecker, D. Umetsu, 1997, Vaccine.

Diminution by vesicular stomatitis virus of acute graft vs host mortality in mice.

D. Umetsu, B. Bloom, T. Romano, 1979, Cellular immunology.

Antigen presentation by human dermal fibroblasts: activation of resting T lymphocytes.

D. Umetsu, H. Jabara, R. Geha, 1986, Journal of immunology.

Immunological mechanisms for desensitization and tolerance in food allergy

D. Umetsu, R. Rachid, 2012, Seminars in Immunopathology.

Understanding microorganisms in the prevention of allergy.

D. Umetsu, 2022, Nature immunology.

EBV transformed B cell lines present to antigen specific T cell clones determinants different from those recognized by antibody in an HLA-DR linked restricted fashion.

D. Umetsu, E. Yunis, R. Geha, 1983, Human immunology.

Mice Fail to Provide B Cell Help Antigen-Primed T Cells from B Cell-Deficient

D. Umetsu, R. DeKruyff, A. Macaulay, 1998 .

The Development of Airway Hyperreactivity in T-bet-Deficient Mice Requires CD1d-Restricted NKT Cells1

D. Umetsu, P. Savage, M. Pichavant, 2009, The Journal of Immunology.

Follicular lymphoma: a model of lymphoid tumor progression in man.

L. Esserman, A. Zelenetz, D. Maloney, 1991, Annals of oncology : official journal of the European Society for Medical Oncology.

Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia.

L. Notarangelo, J. Walter, R. Geha, 2013, Clinical immunology.

Induction of proliferation of human follicular (B type) lymphoma cells by cognate interaction with CD4+ T cell clones.

L. Esserman, D. Umetsu, T. Donlon, 1990, Journal of immunology.

Mucosal Tolerance and Immunity: Regulating the Development of Allergic Disease and Asthma

D. Umetsu, P. Stock, O. Akbari, 2003, International Archives of Allergy and Immunology.

Oral Immunotherapy for Food Allergy: Towards a New Horizon

D. Umetsu, E. Khoriaty, 2012, Allergy, asthma & immunology research.

Changes in antigen-specific T cell number and function during oral desensitization in cow’s milk allergy enabled with omalizumab

K. Nadeau, D. Umetsu, A. K. Singh, 2012, Mucosal Immunology.

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

D. Umetsu, O. Akbari, R. DeKruyff, 2001, Nature Immunology.

Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.

D. Umetsu, C. Hug, S. Shore, 2014, American journal of physiology. Lung cellular and molecular physiology.

Blockade of RGMb inhibits allergen-induced airways disease.

G. Freeman, D. Umetsu, Hyun-Jun Lee, 2019, The Journal of allergy and clinical immunology.

Binding of hepatitis A virus to its cellular receptor 1 inhibits T-regulatory cell functions in humans.

G. Freeman, D. Umetsu, J. Casasnovas, 2012, Gastroenterology.

Natural killer T cells and the regulation of asthma

D. Umetsu, M. Pichavant, R. DeKruyff, 2009, Mucosal Immunology.

Critical Role for IL-13 in the Development of Allergen-Induced Airway Hyperreactivity1

D. Umetsu, A. McKenzie, D. Donaldson, 2001, The Journal of Immunology.

Proliferationto Induce T Cell Conventional Signal 1 and Requires Tim-1 Signaling Substitutes for

Terry B. Strom, Xin Xiao Zheng, Dale T. Umetsu, 2010 .

Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis.

L. Steinman, D. Umetsu, T. Guarino, 1996, The Journal of allergy and clinical immunology.

The regulation of allergy and asthma

D. Umetsu, R. DeKruyff, 2006, Immunological reviews.

A new player on the psoriasis block: IL-17A- and IL-22-producing innate lymphoid cells

D. Umetsu, N. Ward, 2014, The Journal of investigative dermatology.

Microbiota Therapy Acts Via a Regulatory T Cell MyD88/RORγt Pathway to Suppress Food Allergy

G. Gerber, E. Crestani, T. Chatila, 2019, Nature Medicine.

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

A. Rudensky, Ye Zheng, S. Josefowicz, 2012, Nature.

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

G. Barsh, G. Freeman, V. Kuchroo, 2001, Nature Immunology.

PDE4D plays a critical role in the control of airway smooth muscle contraction

D. Umetsu, M. Conti, C. Méhats, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The many paths to asthma: phenotype shaped by innate and adaptive immunity

D. Umetsu, Hye Young Kim, R. DeKruyff, 2010, Nature Immunology.

A natural killer T‐cell subset that protects against airway hyperreactivity

D. Umetsu, P. Savage, N. Baumgarth, 2018, The Journal of allergy and clinical immunology.

Innate immunity in the lung regulates the development of asthma

D. Umetsu, Hye Young Kim, R. DeKruyff, 2014, Immunological reviews.

IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

E. Israel, D. Umetsu, Y. Iwakura, 2014 .

News & Highlights

D. Umetsu, Dale T. Umetsu, 2010, Mucosal Immunology.

latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation

G. Berry, D. Umetsu, G. Thorbecke, 2000 .

CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation.

G. Berry, D. Umetsu, G. Thorbecke, 2000, The Journal of clinical investigation.

Annals of Oncology

Horton, R. A. Miller, A. Lister, 1991, Springer US.

TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

G. Freeman, G. Dranoff, A. Sharpe, 2007, Immunity.

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

G. Freeman, D. Umetsu, J. Casasnovas, 2010, Immunological reviews.

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease.

Lieping Chen, D. Umetsu, Y. Iwakura, 2009, Blood.

High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy

S. Elledge, K. Nadeau, Mamie Z. Li, 2021, Cell reports. Medicine.

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

Ya-Jen Chang, Dirk E. Smith, D. Umetsu, 2011, Nature Immunology.

Long-Term Outcome of Peanut Oral Immunotherapy Facilitated Initially by Omalizumab.

D. Umetsu, Sajjad Rezaei, L. Schneider, 2019, The journal of allergy and clinical immunology. In practice.

Cross-priming of murine B cells with TNP conjugates of hemocyanin and Ficoll: characteristics of primed B cells responding to both antigens.

D. Umetsu, G. Thorbecke, J. Chapman-Alexander, 1979, Journal of immunology.

Th1 and Th2 CD4+ Cells in the Pathogenesis of Allergic Diseases

D. Umetsu, R. DeKruyff, 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Activation of Nonclassical CD1d-Restricted NK T Cells Induces Airway Hyperreactivity in β2-Microglobulin-Deficient Mice1

D. Umetsu, P. Savage, M. Pichavant, 2008, The Journal of Immunology.

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

G. Freeman, D. Umetsu, Wenhui Li, 2013, PLoS pathogens.

Heterogeneity of phenotype in two siblings with adenosine deaminase deficiency.

H. Ochs, D. Umetsu, M. Hershfield, 1994, The Journal of allergy and clinical immunology.

Properties of reticulum cell sarcomas in SJL/J mice. VII. Nature of normal lymphoid cells proliferating in response to tumor cells.

D. Umetsu, G. Thorbecke, S. Lerman, 1979, Cellular immunology.

Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations.

L. Notarangelo, S. Giliani, D. Umetsu, 2008, Blood.

T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.

G. Freeman, D. Umetsu, P. Savage, 2013, The Journal of allergy and clinical immunology.

CHAPTER 32 – Immunology of the Asthmatic Response

D. Umetsu, P. Stock, C. Macaubas, 2010 .

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.

Dirk E. Smith, D. Umetsu, P. Savage, 2012, The Journal of allergy and clinical immunology.

Major histocompatibility restriction of antigen recognition by T cells in a recipient of haplotype mismatched human bone marrow transplantation.

F. Rosen, D. Umetsu, R. Geha, 1983, The Journal of clinical investigation.

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

V. Kuchroo, R. Sobel, S. Khoury, 2007, The Journal of experimental medicine.

Diff erential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and eff ector function

V. Kuchroo, R. Sobel, S. Khoury, 2007 .

Cytotoxic T cell responses to DNA vaccination: dependence on antigen presentation via class II MHC.

S. Levy, H. Maecker, D. Umetsu, 1998, Journal of immunology.

Natural killer T cells regulate the development of asthma

D. Umetsu, M. Pichavant, R. DeKruyff, 2009, Expert review of clinical immunology.

The regulatory role of natural killer T cells in the airways.

D. Umetsu, R. DeKruyff, 2010, The international journal of biochemistry & cell biology.

Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

S. Goya, D. Umetsu, P. Savage, 2008, The Journal of experimental medicine.

OR.49. INKt-Cells Require Ccr4 Binding of Ccl17 to Localize to the Airways Where They Are Necessary and Sufficient for Inducing Airway Hyperreactivity

E. Butcher, D. Umetsu, P. Savage, 2006 .

IL-12 inhibits IL-4 synthesis in keyhole limpet hemocyanin-primed CD4+ T cells through an effect on antigen-presenting cells.

D. Umetsu, S. Wolf, R. DeKruyff, 1995, Journal of immunology.

Budesonide nebulization added to systemic prednisolone in the treatment of acute asthma in children: a double-blind, randomized, controlled trial.

D. Umetsu, M. Mubasher, M. Al-Tannir, 2014, Chest.

Decreases in circulating CD4+CD25hiFOXP3+ cells and increases in intragraft FOXP3+ cells accompany allograft rejection in pediatric liver allograft recipients

D. Umetsu, N. Kambham, C. Esquivel, 2009, Pediatric transplantation.

TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells

G. Freeman, D. Umetsu, D. Bedoret, 2012, Mucosal Immunology.

Innate lymphoid cells and asthma.

D. Umetsu, Hye Young Kim, R. DeKruyff, 2014, The Journal of allergy and clinical immunology.

Innate lymphoid cells responding to IL-33 mediate airway- hyperreactivity independent of adaptive immunity

Dirk E. Smith, D. Umetsu, P. Savage, 2011 .

IL-17-Producing NKT Cells in Airway Inflammation

D. Umetsu, R. DeKruyff, 2011 .

Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D.

S. Jin, D. Umetsu, M. Conti, 2000, Proceedings of the National Academy of Sciences of the United States of America.

In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motif.

T. Chatila, D. Umetsu, H. Kim, 2010, The Journal of allergy and clinical immunology.

Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency.

T. Hope, D. Umetsu, T. Parslow, 1995, Cellular immunology.

Ia-restricted interaction between normal lymphoid cells and SJL lymphoma (RCS) leading to lymphokine production. I. Enhancement and suppression of antibody formation to TI antigens by supernatants and cells from cocultures of RCS and lymphoid cells.

D. Umetsu, T. Hayama, G. Thorbecke, 1983, Cellular immunology.

Immune dysregulation in asthma.

D. Umetsu, R. DeKruyff, 2006, Current opinion in immunology.

Natural killer T cells in the lungs of patients with asthma.

E. Israel, D. Umetsu, M. Pichavant, 2009, The Journal of allergy and clinical immunology.

Reconstitution of germinal center formation in nude mice with Th1 and Th2 clones.

D. Umetsu, E. Secord, G. Thorbecke, 1996, Cellular immunology.

Innate lymphoid cells in asthma: Will they take your breath away?

D. Umetsu, Hye Young Kim, R. DeKruyff, 2016, European journal of immunology.

Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

G. Berry, G. Freeman, A. Sharpe, 2002, Nature Medicine.

Mechanisms by which obesity impacts upon asthma

D. Umetsu, 2016, Thorax.

Allergen immunotherapy with heat‐killed Listeria monocytogenes alleviates peanut and food‐induced anaphylaxis in dogs

D. Umetsu, S. Teuber, B. Buchanan, 2005, Allergy.

IL-33 Drives Augmented Responses to Ozone in Obese Mice

Dirk E. Smith, B. Levy, D. Umetsu, 2016, Environmental health perspectives.

Targeting IgE to facilitate oral immunotherapy for food allergy: a potential new role for anti-IgE therapy?

D. Umetsu, 2014, Expert review of clinical immunology.

Inhibition of the allergic response by regulatory T cells

D. Umetsu, P. Stock, R. DeKruyff, 2006, Current opinion in allergy and clinical immunology.

When engineered to produce latent TGF-beta1, antigen specific T cells down regulate Th1 cell-mediated autoimmune and Th2 cell-mediated allergic inflammatory processes.

D. Umetsu, G. Thorbecke, G. Hochwald, 2000, Cytokine & growth factor reviews.

Reduced prevalence of allergic disease in patients with multiple sclerosis is associated with enhanced IL-12 production.

D. Umetsu, S. Benjaponpitak, R. DeKruyff, 1998, The Journal of allergy and clinical immunology.

A three-week-old infant with invasive pulmonary aspergillosis.

D. Umetsu, L. A. González, J. Kiff, 1994, Annals of allergy.

Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells

Jayoung Kim, D. Di Vizio, M. Freeman, 2014, Cancer biology & therapy.

TIM-1, hepatitis A virus and the hygiene theory of atopy: association of TIM-1 with atopy.

D. Umetsu, R. DeKruyff, J. McIntire, 2005, Journal of pediatric gastroenterology and nutrition.

Consequences of antibiotics and infections in infancy: bugs, drugs, and wheezing.

K. Mandl, D. Umetsu, Mei‐Sing Ong, 2014, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

HLA‐DR‐4‐associated alloreactivity of an HLA‐DR‐3‐ restricted human tetanus toxoid‐specific T cell clone: inhibition of both reactivities by an alloantiserum

R. Geha, D. Umetsu, E. Yunis, 1985, European journal of immunology.

Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice.

V. Kuchroo, Wenda Gao, T. Strom, 2008, The Journal of clinical investigation.

Invariant natural killer T cells in obstructive pulmonary diseases.

D. Umetsu, J. Faul, O. Akbari, 2007, New England Journal of Medicine.

Components Essential for the Generation of Germinal Centers

D. Umetsu, E. Secord, G. Thorbecke, 1998, Developmental immunology.

Abstract 1658: Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: Potential effects on the tumor microenvironment

Jayoung Kim, M. Freeman, D. Umetsu, 2014 .

IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

E. Israel, D. Umetsu, Y. Iwakura, 2013, Nature Medicine.

Reply to Natural killer T cells and CD8+ T cells are dispensable for T cell–dependent allergic airway inflammation

D. Umetsu, O. Akbari, 2006, Nature Network Boston.

Pulmonary Inflammation Induced by Subacute Ozone Is Augmented in Adiponectin-Deficient Mice: Role of IL-17A

D. Umetsu, C. Hug, S. Shore, 2012, The Journal of Immunology.

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia.

Bryanne E. Robson, D. Umetsu, K. Ye, 2009, Blood.

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

D. Umetsu, Wenhui Li, M. Farzan, 2013, PLoS pathogens.

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

D. Umetsu, J. Casasnovas, R. DeKruyff, 2010, Immunological reviews.

TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells

D. Umetsu, N. Baumgarth, O. Akbari, 2010, The Journal of Immunology.

c-Kit inhibitors prevent respiratory viral infection-induced acute asthma via the blockade of innate lymphoid cell activation

D. Umetsu, Alan Chuan-Ying Lai, Ya‐Jen Chang, 2016, The Journal of Immunology.