A. Csiszar

发表

Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

Grant R. Gordon, S. Tarantini, C. Tran, 2017, Experimental Gerontology.

Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by two-photon microscopy & optical coherence tomography.

T. Kiss, S. Tarantini, Z. Ungvari, 2021, American journal of physiology. Heart and circulatory physiology.

Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar.

Farzaneh A. Sorond, B. Merkely, S. Tarantini, 2020, Journal of the American College of Cardiology.

Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood

T. Kiss, J. Wren, S. Tarantini, 2020, GeroScience.

Mechanisms of Vascular Aging.

S. Tarantini, Z. Ungvari, A. Csiszar, 2018, Circulation research.

Monroe P. Turner, B. Rypma, S. Tarantini, 2020, Psychophysiology.

Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2019, GeroScience.

Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults

S. Tarantini, Z. Ungvari, A. Csiszar, 2018, GeroScience.

Cerebral microhemorrhages: mechanisms, consequences, and prevention.

S. Tarantini, Z. Ungvari, A. Csiszar, 2017, American journal of physiology. Heart and circulatory physiology.

Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.

L. Ferrucci, Z. Ungvari, A. Csiszar, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Insulin-like growth factor-1 in CNS and cerebrovascular aging

W. Freeman, F. Deák, Z. Ungvari, 2013, Front. Aging Neurosci..

Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.

Yong Woo Lee, A. Csiszar, T. Herman, 2011, American journal of physiology. Heart and circulatory physiology.

Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression

C. Bass, Z. Ungvari, A. Csiszar, 2011, Neuroscience.

Aging Impairs Myogenic Adaptation to Pulsatile Pressure in Mouse Cerebral Arteries

S. Tarantini, Z. Ungvari, A. Csiszar, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer’s disease using functional laser speckle contrast imaging

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Downregulation of Bone Morphogenetic Protein 4 Expression in Coronary Arterial Endothelial Cells: Role of Shear Stress and the cAMP/Protein Kinase A Pathway

H. Jo, Z. Ungvari, A. Csiszar, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Intramyocardial VEGF-B167 Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy

L. Zentilin, M. Giacca, F. Recchia, 2010, Circulation research.

Oxidative Stress and Endothelial Dysfunction in Pulmonary Arteries of Aged Rats

Z. Ungvari, A. Csiszar, P. Ballabh, 2010, American journal of physiology. Heart and circulatory physiology.

Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging.

Z. Ungvari, A. Csiszar, P. Pacher, 2005, Current vascular pharmacology.

Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries

Z. Ungvari, A. Csiszar, J. Edwards, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.

Z. Ungvari, A. Csiszar, J. Edwards, 2006, The American journal of pathology.

Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells

Z. Ungvari, A. Csiszar, J. Edwards, 2005 .

Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype

Cory B. Giles, J. Wren, S. Tarantini, 2017, Aging cell.

Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment

T. Kiss, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.

Z. Ungvari, A. Csiszar, Kira E Smith, 2007, The American journal of pathology.

Mitochondria and aging in the vascular system

Z. Ungvari, A. Csiszar, W. Sonntag, 2010, Journal of Molecular Medicine.

Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

Z. Ungvari, A. Csiszar, P. Pacher, 2009, American journal of physiology. Heart and circulatory physiology.

Resveratrol Inhibits Aggregation of Platelets from High-risk Cardiac Patients with Aspirin Resistance

Z. Ungvari, A. Csiszar, G. Veress, 2006, Journal of cardiovascular pharmacology.

Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?

Z. Ungvari, A. Csiszar, P. Pacher, 2002, Medical hypotheses.

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging

Shannon M. Conley, T. Kiss, S. Tarantini, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling?

Z. Ungvari, A. Csiszar, M. Wolin, 2006, Antioxidants & redox signaling.

Bone Morphogenetic Protein Inhibition Promotes Neurological Recovery after Intraventricular Hemorrhage

J. Brumberg, A. Csiszar, P. Mouton, 2011, The Journal of Neuroscience.

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.

Leonid Peshkin, Kevin G Becker, Nancy Pleshko, 2008, Cell metabolism.

Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases

T. Kiss, Z. Benyó, S. Tarantini, 2019, GeroScience.

W. Freeman, Z. Ungvari, A. Csiszar, 2018, Neurobiology of Aging.

Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

T. Kiss, S. Tarantini, Z. Ungvari, 2018, GeroScience.

Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection

Cory B. Giles, J. Wren, S. Tarantini, 2015, Aging cell.

Vascular aging and free radicals

Z. Ungvari, A. Csiszar, A. Koller, 2012 .

Impairing the Nrf2-Dependent Antioxidant Response: A Novel Model of Vascular Aging Liver-Specific Knockdown of IGF-1 Decreases Vascular Oxidative Stress Resistance by

D. Sosnowska, F. Recchia, K. Pearson, 2011 .

Age‐associated vascular oxidative stress, Nrf2 dysfunction and NF‐κB activation in the non‐human primate Macaca mulatta

E. Lakatta, D. Sosnowska, Mingyi Wang, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of Nrf2‐mediated antioxidant response

R. de Cabo, D. Sosnowska, Z. Ungvari, 2011, American journal of physiology. Heart and circulatory physiology.

Role of NAD(P)H Oxidase in Superoxide Generation and Endothelial Dysfunction in Goto-Kakizaki (GK) Rats as a Model of Nonobese NIDDM

Z. Ungvari, A. Csiszar, S. Gupte, 2010, PloS one.

Pulmonary Hypertension Resveratrol Prevents Monocrotaline-Induced Pulmonary Hypertension in Rats

R. Cabo, Z. Ungvari, A. Csiszar, 2009 .

Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.

S. Austad, Z. Ungvari, A. Csiszar, 2009, American journal of physiology. Heart and circulatory physiology.

Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging.

Z. Ungvari, A. Csiszar, Kira E Smith, 2007, The American journal of pathology.

Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity

S. Austad, Z. Ungvari, A. Csiszar, 2007, Aging cell.

Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.

Z. Ungvari, A. Csiszar, Kira E Smith, 2006, American journal of physiology. Heart and circulatory physiology.

Temporary opening of the blood-brain barrier with the nitrone compound OKN-007.

A. Csiszar, N. Smith, D. Saunders, 2021, American journal of nuclear medicine and molecular imaging.

Inhibition of NAD(P)H Oxidase Attenuates Aggregation of Platelets from High‐risk Cardiac Patients with Aspirin Resistance

P. Ferdinandy, Z. Ungvari, A. Csiszar, 2007, Pharmacological reports : PR.

Paucity of Pericytes in Germinal Matrix Vasculature of Premature Infants

M. Nedergaard, Z. Ungvari, A. Csiszar, 2007, The Journal of Neuroscience.

Increased interferon‐gamma (IFN‐γ), IL‐10 and decreased IL‐4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)

A. Csiszar, P. Gergely, É. Pócsik, 2000, Clinical and experimental immunology.

Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.

P. Ferdinandy, Z. Ungvari, A. Csiszar, 2007, American journal of physiology. Heart and circulatory physiology.

Endothelial Dysfunction and Vascular Inflammation in Type II Diabetes: Interaction of AGE/RAGE and TNF Signaling Comment on: "AGE/RAGE Produces Endothelial Dysfunction in Coronary Arterioles in Type II Diabetic Mice" by Gao X, Zhang H, Schmidt AM and Zhang C.

Z. Ungvari, A. Csiszar, 2008 .

Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling.

Z. Ungvari, A. Csiszar, 2008, American journal of physiology. Heart and circulatory physiology.

Endothelial dysfunction and vascular inﬂammation in Type 2 diabetes: interaction of AGE/RAGE and TNF- (cid:1) signaling

Z. Ungvari, A. Csiszar, 2008 .

Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions.

Z. Ungvari, A. Csiszar, A. Koller, 2002, American journal of physiology. Heart and circulatory physiology.

Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells Age-Related Decline of Autocrine Pituitary Adenylate Cyclase-Activating Polypeptide

D. Sosnowska, Z. Ungvari, A. Csiszar, 2015 .

promotes endothelial apoptosis in aging Proinflammatory phenotype of coronary arteries

Z. Ungvari, A. Csiszar, J. Edwards, 2013 .

Aging exacerbates obesity-induced impairment of neurovascular coupling and cerebromicrovascular rarefaction: implications for the pathomechanism of vascular cognitive impairment (665.2)

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014 .

Altered mitochondrial energy metabolism may play a role in vascular aging.

Z. Ungvari, A. Csiszar, N. Labinskyy, 2006, Medical hypotheses.

decreasing smooth muscle Ca myogenic tone of skeletal muscle arterioles by Selected Contribution: NO released to flow reduces

D. Sosnowska, Z. Ungvari, A. Csiszar, 2015 .

Aging exacerbates obesity‐induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation

D. Sosnowska, Z. Ungvari, A. Csiszar, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?

Alexandra B. Byrne, S. Austad, D. Sosnowska, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

The pattern of cytokine gene expression in human colorectal carcinoma

A. Balazs, A. Csiszar, T. Szentes, 2008, Pathology & Oncology Research.

CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.

K. Mackie, Z. Ungvari, A. Csiszar, 2007, American journal of physiology. Heart and circulatory physiology.

monocrotaline-induced pulmonary hypertension Role of inhibition of nitric oxide production in

R. Cabo, Z. Ungvari, A. Csiszar, 2015 .

The aging kidney: role of endothelial oxidative stress and inflammation.

Z. Ungvari, A. Csiszar, J. Peti-Peterdi, 2007, Acta physiologica Hungarica.

Cerebral venous congestion exacerbates cerebral microhemorrhages in mice

T. Kiss, S. Tarantini, Z. Ungvari, 2022, GeroScience.

Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014, American journal of physiology. Heart and circulatory physiology.

Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.

D. Sosnowska, Z. Ungvari, A. Csiszar, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Leonid Peshkin, Stuart Maudsley, Michel Bernier, 2014, Cell metabolism.

Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation.

Z. Ungvari, A. Csiszar, A. Koller, 2002, The American journal of pathology.

Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.

S. Austad, D. Sosnowska, P. Mcquary, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Vascular aging in the longest‐living rodent, the naked mole‐rat

Z. Ungvari, A. Csiszar, R. Buffenstein, 2007, American journal of physiology. Heart and circulatory physiology.

Comparison of endothelial function, O2.‐ and H2O2 production and vascular oxidative stress resistance between the longest‐living rodent, the naked mole‐rat and mice

Z. Ungvari, A. Csiszar, R. Buffenstein, 2006, American journal of physiology. Heart and circulatory physiology.

Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury

Z. Ungvari, A. Csiszar, P. Ballabh, 2010, Neuropathology and applied neurobiology.

D. Sosnowska, S. Tarantini, Z. Ungvari, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease.

D. Sosnowska, F. Deák, Z. Ungvari, 2013, American journal of physiology. Heart and circulatory physiology.

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass

T. Kiss, S. Tarantini, Z. Ungvari, 2018, Redox biology.

New Species Longevity Record for the Northern Quahog (=Hard Clam), Mercenaria mercenaria

Z. Ungvari, A. Csiszar, I. Ridgway, 2011 .

Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets.

Z. Ungvari, A. Csiszar, P. Pacher, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.

Z. Ungvari, A. Csiszar, A. Koller, 2004, The American journal of pathology.

Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone

M. Nedergaard, Z. Ungvari, A. Csiszar, 2008, Journal of neuroscience research.

Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role?

Z. Ungvari, A. Csiszar, D. Huffman, 2021, GeroScience.

Mechanisms of vascular aging: new perspectives.

R. de Cabo, Z. Ungvari, A. Csiszar, 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.

S. Tarantini, Z. Ungvari, A. Csiszar, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

CB2 cannabinoid receptor stimulation attenuates TNF‐alpha‐induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte‐endothelial adhesion.

Z. Ungvari, A. Csiszar, P. Pacher, 2008 .

Resveratrol attenuates TNFalfa‐induced activation of coronary arterial endothelial cells: role of NF‐kB inhibition

Z. Ungvari, A. Csiszar, N. Labinskyy, 2007 .

Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies

Dee H. Wu, Z. Ungvari, A. Csiszar, 2022, Oxidative medicine and cellular longevity.

Tumor Necrosis Factor-Increased Superoxide Production in Coronary Arteries in Hyperhomocysteinemia : Role Print

A. Csiszar, J. Edwards, P. Kaminski, 2003 .

Increased Superoxide Production in Coronary Arteries in Hyperhomocysteinemia : Role of TNF α , NAD ( P ) H Oxidase and iNOS

Z. Ungvari, A. Csiszar, J. Edwards, 2003 .

Vasoprotective effects of lifespan‐extending peripubertal GH replacement in Lewis dwarf rats

Z. Ungvari, A. Csiszar, P. Ballabh, 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

Decreased lifespan in female "Munchkin" actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity.

S. Austad, Z. Ungvari, A. Csiszar, 2022, GeroScience.

Vasoprotective effects of caloric restriction in aging

R. Cabo, Z. Ungvari, A. Csiszar, 2010 .

Obesity-induced Cognitive Impairment in Older Adults: a Microvascular Perspective.

T. Kiss, S. Tarantini, Z. Ungvari, 2020, American journal of physiology. Heart and circulatory physiology.

Studies on the antibodies to human herpesvirus type 6 among Hungarian patients with asymptomatic HIV infection

A. Csiszar, J. Ongrádi, K. Nagy, 2008, Pathology & Oncology Research.

Lysyl oxidases as driving forces behind age-related macrovascular rigidity.

A. Csiszar, P. Balasubramanian, 2019, American journal of physiology. Heart and circulatory physiology.

CD82-TRPM7-Numb signaling mediates age-related cognitive impairment

T. Kiss, Jing Shi, Z. Ungvari, 2020, GeroScience.

Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction

Joy W. Chang, R. de Cabo, Suresh Poosala, 2008, Proceedings of the National Academy of Sciences.

Free radicals in aging - An evolutionary perspective

Z. Ungvari, A. Csiszar, 2012 .

Ionizing radiation promotes the acquisition of a senescence‐associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosens (665.3)

D. Sosnowska, F. Deák, Z. Ungvari, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease.

Z. Ungvari, A. Csiszar, 2004, Medical hypotheses.

Systemic hypoxia reverses whole brain radiation‐induced microvascular rarefaction

A. Csiszar, T. Herman, Salahuddin Ahmad, 2011 .

Increased pulse wave velocity is related to impaired working memory and executive function in older adults with metabolic syndrome.

Z. Ungvari, A. Csiszar, D. Proctor, 2022, GeroScience.

A pilot study on the antibodies to HHV-6 variants and HHV-7 in CSF of MS patients.

L. Vécsei, A. Csiszar, J. Ongrádi, 1999, Journal of neurovirology.

Insulin-like growth factor 1 deﬁciency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype manifestation of

Cory B. Giles, J. Wren, S. Tarantini, 2017 .

Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.

H. Saito, Z. Ungvari, A. Csiszar, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Farzaneh A. Sorond, S. Tarantini, Z. Ungvari, 2021, Scientific Reports.

Angiogenic inhibition reduces germinal matrix hemorrhage

S. Goldman, Nanhong Lou, M. Nedergaard, 2007, Nature Medicine.

Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists.

M. Massett, Z. Ungvari, A. Csiszar, 2002, American journal of physiology. Heart and circulatory physiology.

Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions

Shannon M. Conley, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Increased Superoxide Production in Coronary Arteries in Hyperhomocysteinemia: Role of Tumor Necrosis Factor-&agr;, NAD(P)H Oxidase, and Inducible Nitric Oxide Synthase

Gabor Kaley, Z. Ungvari, A. Csiszar, 2003, Arteriosclerosis, thrombosis, and vascular biology.

HYPERHOMOCYSTEINEMIA-INDUCED PRO-INFLAMMATORY AND PRO-ATHEROSCLEROTIC CHANGES IN CORONARY ARTERIES

December, A. Csiszar, 2002 .

Caloric Restriction Confers Anti‐Oxidative, Pro‐Angiogenic, and Anti‐Inflammatory Effects and Promotes Anti‐Aging miRNA Expression Profile in Cerebromicrovascular Endothelial Cells of Aged Rats

Cory B. Giles, J. Wren, D. Sosnowska, 2014, American journal of physiology. Heart and circulatory physiology.

Resveratrol induces mitochondrial biogenesis in endothelial cells

Z. Ungvari, A. Csiszar, Hanrui Zhang, 2009, American journal of physiology. Heart and circulatory physiology.

Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.

R. de Cabo, Z. Ungvari, A. Csiszar, 2008, American journal of physiology. Heart and circulatory physiology.

What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol

J. Pezzuto, N. Nalini, T. Szekeres, 2011, PloS one.

Liver‐specific knockdown of IGF‐1 decreases vascular oxidative stress resistance by impairing the Nrf2‐dependent antioxidant response

D. Sosnowska, Z. Ungvari, A. Csiszar, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Endothelial function and vascular oxidative stress in long‐lived GH/IGF‐deficient Ames dwarf mice

S. Austad, Z. Ungvari, A. Csiszar, 2008, American journal of physiology. Heart and circulatory physiology.

Mitochondrial Protection by Resveratrol

R. de Cabo, J. Baur, Z. Ungvari, 2011, Exercise and sport sciences reviews.

Increased mitochondrial H2O2 production promotes endothelial NF- B activation in aged rat arteries

Z. Ungvari, A. Csiszar, N. Labinskyy, 2007 .

Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter

D. Boas, S. Sakadžić, S. Tarantini, 2023, GeroScience.

Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.

S. Tarantini, Z. Ungvari, A. Csiszar, 2017, American journal of physiology. Heart and circulatory physiology.

Obesity in aging exacerbates blood brain barrier disruption, neuroinflammation and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta‐amyloid generation and Alzheimer’s disease (665.1)

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Oxidative stress and accelerated vascular aging: implications for cigarette smoking.

Z. Ungvari, A. Csiszar, P. Pacher, 2009, Frontiers in bioscience.

Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline

Cory B. Giles, T. Kiss, W. Freeman, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice

S. Tarantini, Z. Ungvari, A. Csiszar, 2019, GeroScience.

Resveratrol attenuates TNF-α-induced activation of coronary arterial endothelial cells: role of NF-κB inhibition

Z. Ungvari, A. Csiszar, N. Labinskyy, 2006 .

Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype

Z. Benyó, S. Tarantini, Z. Ungvari, 2021, GeroScience.

Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects

T. Kiss, J. Wren, S. Tarantini, 2020, GeroScience.

Endothelial dysfunction and angiogenesis impairment in the ageing vasculature

Cory B. Giles, T. Kiss, J. Wren, 2018, Nature Reviews Cardiology.

Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice

P. Rabinovitch, S. Tarantini, Z. Ungvari, 2018, Aging cell.

Resveratrol Prevents Monocrotaline‐induced Pulmonary Hypertension in Rats

Z. Ungvari, A. Csiszar, R. Mathew, 2008, Hypertension.

Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain

T. Kiss, S. Tarantini, Z. Ungvari, 2022, GeroScience.

Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain

T. Kiss, S. Tarantini, Z. Ungvari, 2020, GeroScience.

Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.

A. Csiszar, T. Hintze, P. Pacher, 2005, American journal of physiology. Heart and circulatory physiology.

The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances.

Z. Ungvari, A. Csiszar, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Inflammation and Endothelial Dysfunction during Aging: Role of Nf-κb

E. Lakatta, Mingyi Wang, Z. Ungvari, 2022 .

Treatment with the cytochrome P450 ω‐hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats

D. Sosnowska, S. Tarantini, Z. Ungvari, 2013, British journal of pharmacology.

Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging

Shannon M. Conley, S. Tarantini, Z. Ungvari, 2022, Frontiers in Aging Neuroscience.

Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling

Shannon M. Conley, T. Kiss, J. Wren, 2022, GeroScience.

Cognitive decrement in older adults with symptomatic peripheral artery disease

S. Waldstein, Z. Ungvari, A. Csiszar, 2021, GeroScience.

Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice

M. Lindsey, S. Tarantini, Z. Ungvari, 2021, GeroScience.

Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment

Shannon M. Conley, P. Sótonyi, Z. Ungvari, 2021, GeroScience.

IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging

T. Kiss, Z. Benyó, S. Tarantini, 2021, GeroScience.

Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain

T. Kiss, S. Tarantini, Z. Ungvari, 2020, GeroScience.

T. Kiss, J. Wren, S. Tarantini, 2020, GeroScience.

Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging

T. Kiss, Z. Benyó, S. Tarantini, 2019, GeroScience.

Shannon M. Conley, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

T. Kiss, D. Sinclair, J. Baur, 2019, Redox biology.

T. Kiss, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

T. Kiss, S. Tarantini, Z. Ungvari, 2018, GeroScience.

Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults

S. Tarantini, Z. Ungvari, A. Csiszar, 2018, GeroScience.

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer’s disease using functional laser speckle contrast imaging

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan

Z. Ungvari, A. Csiszar, C. Georgescu, 2017, GeroScience.

The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer

Z. Ungvari, A. Csiszar, Richard A. Miller, 2017, GeroScience.

Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging

Cory B. Giles, J. Wren, S. Tarantini, 2016, AGE.

IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis

Cory B. Giles, J. Wren, S. Tarantini, 2016, AGE.

IGF‐1 Regulates Vertebral Bone Aging Through Sex‐Specific and Time‐Dependent Mechanisms

Z. Ungvari, A. Csiszar, Y. Ikeno, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.

J. Baur, S. Tarantini, Z. Ungvari, 2015, American journal of physiology. Heart and circulatory physiology.

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

S. Tarantini, Z. Ungvari, A. Csiszar, 2015, Aging cell.

IGF-1 Deficiency Impairs Cerebral Myogenic Autoregulation in Hypertensive Mice

D. Sosnowska, S. Tarantini, Z. Ungvari, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

D. Sosnowska, F. Deák, S. Tarantini, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Growth hormone and IGF‐1 deficiency exacerbate high fat diet‐induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging

D. Sosnowska, Z. Ungvari, A. Csiszar, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

High Pressure Induces Superoxide Production in Isolated Arteries Via Protein Kinase C–Dependent Activation of NAD(P)H Oxidase

Z. Ungvari, A. Csiszar, A. Koller, 2003, Circulation.

Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation–induced impairment of neurovascular coupling responses protecting cognitive function in mice

T. Kiss, S. Tarantini, Z. Ungvari, 2020, GeroScience.

Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice

F. Deák, S. Tarantini, Z. Ungvari, 2015, Journal of Cerebral Blood Flow and Metabolism.

Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.

Cory B. Giles, J. Wren, D. Sosnowska, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Cardiovascular and Cerebrovascular Aging–New Mechanisms and Insights: Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

D. Sosnowska, S. Tarantini, Z. Ungvari, 2014 .

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan

Z. Ungvari, A. Csiszar, C. Georgescu, 2017, GeroScience.

Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency

S. Austad, Z. Ungvari, A. Csiszar, 2008, AGE.

Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice

T. Kiss, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Role of endothelial NAD+ deficiency in age-related vascular dysfunction.

T. Kiss, J. Baur, S. Tarantini, 2019, American journal of physiology. Heart and circulatory physiology.

Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation

S. Tarantini, Z. Ungvari, A. Csiszar, 2019, Front. Genet..

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2019, American journal of physiology. Heart and circulatory physiology.

Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research

S. Tarantini, Z. Ungvari, A. Csiszar, 2019, GeroScience.

Gabor Nemeth, Andriy Yabluchanskiy, Shannon M. Conley, 2019, GeroScience.

Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats.

Z. Ungvari, A. Csiszar, S. Gupte, 2008, American journal of physiology. Heart and circulatory physiology.

Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice

T. Kiss, Z. Benyó, S. Tarantini, 2021, GeroScience.

Cerebral venous congestion exacerbates cerebral microhemorrhages in mice

T. Kiss, S. Tarantini, Z. Ungvari, 2022, GeroScience.

Hypertension-induced cognitive impairment: from pathophysiology to public health

Farzaneh A. Sorond, B. Merkely, S. Tarantini, 2021, Nature Reviews Nephrology.

Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice

T. Kiss, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2017, GeroScience.

Connective tissue growth factor (CTGF) in age-related vascular pathologies

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment

F. Deák, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Z. Ungvari, A. Csiszar, Richard A. Miller, 2017, GeroScience.

Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects

Cory B. Giles, T. Kiss, J. Wren, 2019, GeroScience.

Advances and challenges in geroscience research: An update.

S. Tarantini, Z. Ungvari, A. Csiszar, 2018, Physiology international.

Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer’s disease

S. Tarantini, Z. Ungvari, A. Csiszar, 2021, GeroScience.

Retinal biomarkers for Alzheimer’s disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

Shannon M. Conley, Z. Ungvari, A. Csiszar, 2020, GeroScience.

CD82-TRPM7-Numb signaling mediates age-related cognitive impairment

T. Kiss, Jing Shi, Z. Ungvari, 2020, GeroScience.

Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction

T. Kiss, S. Tarantini, Z. Ungvari, 2018, GeroScience.

Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Sleep deprivation alters task‐related changes in functional connectivity of the frontal cortex: A near‐infrared spectroscopy study

Farzaneh A. Sorond, S. Tarantini, Z. Ungvari, 2021, Brain and behavior.

Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction

T. Kiss, S. Tarantini, Z. Ungvari, 2018, GeroScience.

Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition

Farzaneh A. Sorond, S. Carmichael, V. Hachinski, 2021, GeroScience.

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2019, GeroScience.

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease

T. Kiss, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling

S. Tarantini, Z. Ungvari, A. Csiszar, 2020, GeroScience.

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

R. de Cabo, T. Kiss, F. Deák, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment

F. Deák, S. Tarantini, Z. Ungvari, 2017, GeroScience.

Whole Brain Radiation-Induced Vascular Cognitive Impairment: Mechanisms and Implications

Yong Woo Lee, Z. Ungvari, A. Csiszar, 2013, Journal of Vascular Research.

Whole Brain Radiation-Induced Impairments in Learning and Memory Are Time-Sensitive and Reversible by Systemic Hypoxia

Yong Woo Lee, A. Csiszar, M. Mitschelen, 2012, PloS one.

Effect of Prenatal Glucocorticoids on Cerebral Vasculature of the Developing Brain

Z. Ungvari, A. Csiszar, P. Ballabh, 2010, Stroke.

CORRIGENDUM: SRT1720 improves survival and healthspan of obese mice

E. Mercken, R. de Cabo, M. Gorospe, 2013, Scientific Reports.

Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.

W. Freeman, F. Deák, Z. Ungvari, 2016, The journals of gerontology. Series A, Biological sciences and medical sciences.

Companion animals likely do not spread COVID-19 but may get infected themselves

S. Tarantini, Z. Ungvari, A. Csiszar, 2020, GeroScience.

[Presence of antibodies to human herpesvirus type 6 and 7 in Hungarian children].

A. Csiszar, J. Sólyom, A. Horváth, 1999, Orvosi hetilap.

Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission

S. Tarantini, Z. Ungvari, A. Csiszar, 2021, GeroScience.

Extended Production of Cortical Interneurons into the Third Trimester of Human Gestation.

A. Csiszar, P. Ballabh, K. Yoshikawa, 2016, Cerebral cortex.

Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease

Z. Ungvari, A. Csiszar, A. Gardner, 2018, Angiology.

Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease

Z. Ungvari, A. Csiszar, A. Gardner, 2017, Journal of vascular surgery.

Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease

Z. Ungvari, A. Csiszar, A. Gardner, 2016, AGE.

Influence of diabetes on ambulation and inflammation in men and women with symptomatic peripheral artery disease

D. Sosnowska, Z. Ungvari, A. Csiszar, 2015, Journal of clinical & translational endocrinology.

Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.

D. Sosnowska, Z. Ungvari, A. Csiszar, 2015, Journal of vascular surgery.

Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease

Danuta Sosnowska, D. Sosnowska, Z. Ungvari, 2015, Angiology.

Impaired Vascular Endothelial Growth Factor A and Inflammation in Patients With Peripheral Artery Disease

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014, Angiology.

Greater Endothelial Apoptosis and Oxidative Stress in Patients with Peripheral Artery Disease

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014, International journal of vascular medicine.

Anti‐inflammatory effects of resveratrol: possible role in prevention of age‐related cardiovascular disease

A. Csiszar, 2011, Annals of the New York Academy of Sciences.

Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).

S. Austad, D. Sosnowska, P. Mcquary, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Inflammation and endothelial dysfunction during aging: role of NF-kappaB.

E. Lakatta, Mingyi Wang, Z. Ungvari, 2008, Journal of applied physiology.

Characterisation of cytokine mRNA expression in tumour-infiltrating mononuclear cells and tumour cells freshly isolated from human colorectal carcinomas.

A. Csiszar, D. Émilie, T. Szentes, 2001, European cytokine network.

Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?

F. Recchia, Z. Ungvari, A. Csiszar, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.

Z. Ungvari, A. Csiszar, S. Lehoux, 2009, Antioxidants & redox signaling.

Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.

H. Jo, Z. Ungvari, A. Csiszar, 2008, American journal of physiology. Heart and circulatory physiology.

Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.

Pál Pacher, B. Cravatt, Z. Ungvari, 2007 .

A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.

D. Sosnowska, Z. Ungvari, A. Csiszar, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

R. de Cabo, F. Recchia, A. Feher, 2010, American journal of physiology. Heart and circulatory physiology.

Oxidative–Nitrosative Stress in a Rabbit Pup Model of Germinal Matrix Hemorrhage: Role of NAD(P)H Oxidase

Z. Ungvari, A. Csiszar, P. Ballabh, 2009, Stroke.

Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar Function

Z. Ungvari, A. Csiszar, J. Edwards, 2002, Circulation research.

Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.

Z. Ungvari, A. Csiszar, J. Edwards, 2004, Physiological genomics.

Oxidative stress in vascular senescence: lessons from successfully aging species.

S. Austad, Z. Ungvari, A. Csiszar, 2008, Frontiers in bioscience : a journal and virtual library.

Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease

S. Tarantini, Z. Ungvari, A. Csiszar, 2022, Frontiers in Aging Neuroscience.

Pharmacological Strategies to Retard Cardiovascular Aging.

R. de Cabo, E. Lakatta, Z. Ungvari, 2016, Circulation research.

Caloric restriction and cardiovascular disease

R. Cabo, Z. Ungvari, A. Csiszar, 2010 .

Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.

D. Sosnowska, Z. Ungvari, A. Csiszar, 2013, American journal of physiology. Heart and circulatory physiology.

Mitochondria in Cardiovascular Physiology and Disease Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease : from mechanisms to therapeutics

A. Csiszar, C. Leeuwenburgh, R. Calvani, 2013 .

Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging

D. Sosnowska, R. Cabo, Z. Ungvari, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells Role of Nuclear Factor- (cid:1)(cid:2) Activation by Tumor Necrosis Factor- (cid:3) , H 2 O 2 , and High Intravascular Pressure

Z. Ungvari, A. Csiszar, A. Koller, 2005 .

Mechanisms Underlying Caloric Restriction and Lifespan Regulation: Implications for Vascular Aging

R. de Cabo, Z. Ungvari, A. Csiszar, 2008, Circulation research.

Vascular Inflammation in Aging

Z. Ungvari, A. Csiszar, G. Kaley, 2004, Herz.

Oxidative Stress in Vascular Aging

Z. Ungvari, A. Csiszar, 2010 .

Mechanisms Underlying Caloric Restriction and Lifespan Regulation: Implications for Vascular Aging

R. de Cabo, R. Cabo, Z. Ungvari, 2008, Circulation research.

Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.

E. Lakatta, D. Sosnowska, Mingyi Wang, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Premature death and age-related cardiac dysfunction in male eNOS-knockout mice.

A. Csiszar, S. Mital, T. Hintze, 2004, Journal of molecular and cellular cardiology.

SRT1720 improves survival and healthspan of obese mice

E. Mercken, R. de Cabo, M. Gorospe, 2011, Scientific reports.

The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach.

Z. Ungvari, A. Csiszar, M. Goligorsky, 2009, The American journal of pathology.

Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairment.

Farzaneh A. Sorond, S. Studenski, L. Lipsitz, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Resveratrol Increases Vascular Oxidative Stress Resistance

Z. Ungvari, A. Csiszar, Xiangmin Zhao, 2007, American journal of physiology. Heart and circulatory physiology.

Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.

Z. Ungvari, A. Csiszar, G. Veress, 2006, Current medicinal chemistry.

Pathophysiology of Hypertension Role of 20-HETE , TRPC channels , and BKCa in dysregulation of pressure-induced Ca 2 signaling and myogenic constriction of cerebral arteries in aged hypertensive mice

D. Sosnowska, Z. Ungvari, A. Csiszar, 2013 .

SRT1720 improves survival and healthspan of obese mice

E. Mercken, R. de Cabo, M. Gorospe, 2011, Scientific reports.

Small Vessels – Big Problems : Novel Insights into Microvascular Mechanisms of Diseases Purinergic glio-endothelial coupling during neuronal activity : role of P 2 Y 1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex

J. Baur, S. Tarantini, Z. Ungvari, 2015 .

Cyclosporin A does not block exercise-induced cardiac hypertrophy

A. Csiszar, J. Edwards, Shuangdan Sun, 2002 .

Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.

Z. Ungvari, A. Csiszar, K. Fung, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet

R. de Cabo, K. Pearson, J. Allard, 2016, Aging.

Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults

Farzaneh A. Sorond, S. Tarantini, Z. Ungvari, 2021, PloS one.

Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1

K. Pearson, R. Cabo, Z. Ungvari, 2009, Mechanisms of Ageing and Development.

Adaptive induction of NF‐E2–Related Factor‐2‐driven antioxidant genes in endothelial cells in response to hyperglycemia

Kevin Pearson, R. de Cabo, F. Recchia, 2011, American journal of physiology. Heart and circulatory physiology.

Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2018, GeroScience.

Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging : role of circulating factors and SIRT 1

K. Pearson, R. Cabo, Z. Ungvari, 2009 .

Circulating factors induced by caloric restriction in the non‐human primate Macaca mulatta activate angiogenic processes in endothelial cells

R. Weindruch, R. Colman, D. Sosnowska, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Cerebral small vessel disease pathology in COVID-19 patients: A systematic review

S. Tarantini, Z. Ungvari, A. Csiszar, 2023, Ageing Research Reviews.

Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.

S. Waldstein, P. Sótonyi, S. Tarantini, 2022, American journal of physiology. Heart and circulatory physiology.

Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor

J. Wren, Z. Ungvari, A. Csiszar, 2023, Cellular and Molecular Life Sciences.

Risk of HHV-6A primary and recurrent infections during the course of AIDS.

A. Csiszar, A. Horváth, J. Ongrádi, 1999, Journal of acquired immune deficiency syndromes.

Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin

Shannon M. Conley, S. Tarantini, Z. Ungvari, 2023, GeroScience.

Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer’s disease

T. Kiss, S. Tarantini, Z. Ungvari, 2020, GeroScience.

Psychological resilience and competence: key promoters of successful aging and flourishing in late life

Z. Ungvari, A. Csiszar, G. Purebl, 2023, GeroScience.

Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.

Z. Ungvari, A. Csiszar, P. Ballabh, 2010, Brain : a journal of neurology.

Identification of Rocks on Planetary Surface Using Husar-9 Rover Camera: Field Work Simulations with Hunveyor-9 Space Probe Model System at Eötvös High School, Tata, Hungary

A. Csiszar, S. Bérczi, T. Varga, 2009 .

The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms

Z. Ungvari, A. Csiszar, S. Kunutsor, 2023, GeroScience.

Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain

T. Kiss, S. Tarantini, Z. Ungvari, 2023, Aging cell.

Midlife Obesity Impairs Neurovascular Coupling Responses

S. Tarantini, Z. Ungvari, A. Csiszar, 2020, Obesity.

Biotin-conjugated fusogenic liposomes for high-quality cell purification

Z. Ungvari, A. Csiszar, N. Hersch, 2016, Journal of biomaterials applications.

Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.

Z. Ungvari, A. Csiszar, Á. Csiszár, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells: Role of Nuclear Factor-&kgr;&Bgr; Activation by Tumor Necrosis Factor-&agr;, H2O2, and High Intravascular Pressure

Z. Ungvari, A. Csiszar, J. Edwards, 2005, Circulation.

Farzaneh A. Sorond, T. Kiss, S. Tarantini, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Telomere Biology and Cardiovascular Disease Vascular Cell Senescence: Contribution to Atherosclerosis Stem Cells and the Regeneration of the Aging Cardiovascular System Mechanisms of Cardiovascular Disease in Accelerated Aging Syndromes Mechanisms Underlying Caloric Restriction and Lifespan Regulati

R. Cabo, Z. Ungvari, A. Csiszar, 2008 .

IGF‐1 Deficiency Exacerbates Hypertension‐Induced Cerebral Microhemorrhages in Mice, Mimicking the Aging Phenotype

S. Tarantini, Z. Ungvari, A. Csiszar, 2015 .

T. Kiss, J. Wren, S. Tarantini, 2020, GeroScience.

Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study

S. Tarantini, Z. Ungvari, A. Csiszar, 2023, PloS one.

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.

T. Kiss, D. Sinclair, J. Baur, 2020, The FASEB Journal.

MCI patients with COVID-19 Have Increased Progression to Dementia at 18 months (S39.010)

Z. Ungvari, A. Csiszar, C. Prodan, 2023, Wednesday, April 26.

Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice

Z. Ungvari, A. Csiszar, A. Richardson, 2018, GeroScience.

Vascular inflammation in aging: role of increased mitochondrial H2O2 production in endothelial NF‐kB activation

Z. Ungvari, A. Csiszar, N. Labinskyy, 2008 .

Resveratrol may attenuate vascular inflammation in aging

Z. Ungvari, A. Csiszar, N. Labinskyy, 2006 .

Galectin-1 as a marker for microglia activation in the aging brain

T. Kiss, A. Csiszar, G. Szebeni, 2023, Brain Research.

Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures

S. Tarantini, Z. Ungvari, A. Csiszar, 2023, GeroScience.

Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.

B. Cravatt, Z. Ungvari, A. Csiszar, 2007, American journal of physiology. Heart and circulatory physiology.

T. Kiss, S. Tarantini, Z. Ungvari, 2019, GeroScience.

Nicotinamide mononucleotide (NMN) supplementation promotes anti‐aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti‐atherogenic effects.

Cory B. Giles, T. Kiss, J. Wren, 2020, The FASEB Journal.

Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging

Cory B. Giles, J. Wren, S. Tarantini, 2016, AGE.

Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain

T. Kiss, Z. Benyó, S. Tarantini, 2023, GeroScience.

Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research

S. Tarantini, Z. Ungvari, A. Csiszar, 2019, GeroScience.

Supplemental Data Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

L. Peshkin, R. de Cabo, D. Ingram, 2008 .

Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice

Z. Ungvari, A. Csiszar, A. Richardson, 2018, GeroScience.

Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression

C. Bass, Z. Ungvari, A. Csiszar, 2011, Neuroscience.

Increased mitochondrial H2O2 production promotes endothelial NF-κB activation in aged rat arteries

Z. Ungvari, A. Csiszar, N. Labinskyy, 2007 .

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.

R. de Cabo, D. Sosnowska, Z. Ungvari, 2011, American journal of physiology. Heart and circulatory physiology.

R. Cabo, Z. Ungvari, A. Csiszar, 2008 .

Cerebral microhemorrhages: mechanisms, consequences, and prevention.

S. Tarantini, Z. Ungvari, A. Csiszar, 2017, American journal of physiology. Heart and circulatory physiology.

Z. Ungvari, A. Csiszar, 2008 .

Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury

Z. Ungvari, A. Csiszar, C. Chua, 2010, Neuropathology and applied neurobiology.

Cardiovascular and Cerebrovascular Aging—New Mechanisms and Insights: Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats

Cory B. Giles, J. Wren, D. Sosnowska, 2014 .

Supplemental Data Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

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