J. Grimsley

发表

Rational Enzyme Design: Computer Modeling and Site-directed Mutagenesis for the Modification of Catalytic Specificity in Organophosphorus Hydrolase

S. Harvey, K. Lai, J. Grimsley, 1996, CHIMIA.

Modification of near active site residues in organophosphorus hydrolase reduces metal stoichiometry and alters substrate specificity.

K. Lai, J. Grimsley, J. Wild, 1999, Biochemistry.

Rational design of organophosphorus hydrolase for altered substrate specificities.

K. Lai, J. Grimsley, J. Wild, 1999, Chemico-biological interactions.

Structural and mutational studies of organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site.

J. Grimsley, J. Wild, Barbara Calamini, 2005, Archives of biochemistry and biophysics.

Organophosphorus hydrolase is a remarkably stable enzyme that unfolds through a homodimeric intermediate.

C. Pace, J. M. Scholtz, J. Grimsley, 1997, Biochemistry.

Fluorescence-based sensing of p-nitrophenol and p-nitrophenyl substituent organophosphates.

Aleksandr Simonian, J. Grimsley, J. Wild, 2007, Analytica chimica acta.

Production of the bioscavenger butyrylcholinesterase in maize

J. Grimsley, Celine A. Hayden, J. Howard, 2017, Molecular Breeding.

Ancillary Function of Housekeeping Enzymes: Fortuitous Degradation of Environmental Contaminants

J. Grimsley, J. Wild, R. Gold, 2000 .

From Biological Diversity to Structure-Function Analysis: Protein Engineering in Aspartate Transcarbamoylase

J. Grimsley, J. Wild, M. Wales, 1990 .

Neurotoxic Organophosphate Degradation with Polyvinyl Alcohol Gel-Immobilized Microbial Cells

B. Dale, J. Grimsley, J. Wild, 1998 .

Subunit composition and domain structure of the Spo0A sporulation transcription factor of Bacillus subtilis.

J. Hoch, M. Strauch, G. Spiegelman, 1994, The Journal of biological chemistry.

Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol.

J. Grimsley, J. Wild, M. Wales, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Analysis of hydride transfer and cofactor fluorescence decay in mutants of dihydrofolate reductase: possible evidence for participation of enzyme molecular motions in catalysis.

J. Kraut, J. Grimsley, D. Magde, 1991, Biochemistry.

Analysis by pulsed-field gel electrophoresis of DNA double-strand breakage and repair in Deinococcus radiodurans and a radiosensitive mutant.

K. Minton, J. Grimsley, E. P. Clark, 1991, International journal of radiation biology.

Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase.

J. Hoch, J. Grimsley, J A Hoch, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Enzyme-based biosensor for the direct detection of fluorine-containing organophosphates

Joseph S. Schoeniger, Aleksandr Simonian, Tu-Chen Cheng, 2001 .

Dramatically stabilized phosphotriesterase-polymers for nerve agent degradation.

J. Grimsley, J. Wild, A. Russell, 1997, Biotechnology and bioengineering.

Active Site Modifications of Organophosphorus Hydrolase for Improved Detoxification of Organophosphorus Neurotoxins

J. Sacchettini, J. Grimsley, J. Wild, 2000 .

Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol.

J. Grimsley, J. Wild, M. Wales, 2010, Journal of controlled release : official journal of the Controlled Release Society.