Mitsunori Kato

发表

Electrostatic basis for enzyme catalysis.

A. Warshel, P. K. Sharma, Mitsunori Kato, 2006, Chemical reviews.

Modeling electrostatic effects in proteins.

Arieh Warshel, A. Warshel, W. W. Parson, 2006, Biochimica et biophysica acta.

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.

Christopher T. Jones, K. Hoffmaster, Mitsunori Kato, 2014, Bioorganic & medicinal chemistry letters.

Exploring the origin of the ion selectivity of the KcsA potassium channel

Arieh Warshel, A. Warshel, Mitsunori Kato, 2003, Proteins.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Dual Allosteric Inhibition of SHP2 Phosphatase.

Sarah L. Williams, S. Blacklow, M. Glick, 2018, ACS chemical biology.

Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.

Sarah L. Williams, Robert Koenig, Mitsunori Kato, 2019, Journal of medicinal chemistry.

Quantitative Phosphoproteomic Analysis of IRS1 in Skeletal Muscle from Men with Normal Glucose Tolerance or Type 2 Diabetes: A Case-Control Study.

Mitsunori Kato, J. Zierath, A. Krook, 2021, Metabolism: clinical and experimental.

Relativistic configuration interaction and coupled cluster methods using four-component spinors : Magnetic shielding constants of HX and CH3X (X = F, Cl, Br, I)

H. Nakatsuji, Mitsunori Kato, M. Hada, 2005 .

Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models.

Y. Yagi, Mitsunori Kato, Monish Jain, 2017, Journal of medicinal chemistry.

Small-molecule WNK inhibition regulates cardiovascular and renal function.

Y. Yagi, P. Hoffmann, Mitsunori Kato, 2016, Nature chemical biology.

Stopped-Flow Small-Angle X-Ray Scattering Study on the Acid-Denaturation of Taka-Amylase A

N. Kasai, Mitsunori Kato, Y. Hata, 1986 .

Structure-Activity Relationship Evaluation of Wasp Toxin β-PMTX Leads to Analogs with Superior Activity for Human Neuronal Sodium Channels.

Mitsunori Kato, Tejas P Pathak, Catherine E. Garrison, 2019, ACS medicinal chemistry letters.

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.

Sarah L. Williams, W. Sellers, Z. Deng, 2020, Journal of medicinal chemistry.

Through the channel and around the channel: Validating and comparing microscopic approaches for the evaluation of free energy profiles for ion penetration through ion channels.

A. Warshel, Mitsunori Kato, 2005, The journal of physical chemistry. B.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ping Zhu, Gang Liu, Peter Fekkes, 2016, Nature.

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.

Sarah L. Williams, Robert Koenig, Mitsunori Kato, 2019, Journal of medicinal chemistry.

Combined Free-Energy Calculation and Machine Learning Methods for Understanding Ligand Unbinding Kinetics

Pedro J. Buigues, Callum J. Dickson, S. Parsons, 2021, bioRxiv.

A small-molecule inhibitor of C5 complement protein

M. Schirle, Mitsunori Kato, G. Michaud, 2019, Nature Chemical Biology.

Human Carboxymethylenebutenolidase as a Bioactivating Hydrolase of Olmesartan Medoxomil in Liver and Intestine

Mitsunori Kato, T. Izumi, A. Kurihara, 2010, The Journal of Biological Chemistry.

Remodeling of the SCF complex‐mediated ubiquitination system by compositional alteration of incorporated F‐box proteins

K. Kito, K. Ota, Mitsunori Kato, 2010, Proteomics.

The barrier for proton transport in aquaporins as a challenge for electrostatic models: The role of protein relaxation in mutational calculations

Arieh Warshel, Andrei V. Pisliakov, Andrei V Pisliakov, 2006, Proteins.

Apparent NAC effect in chorismate mutase reflects electrostatic transition state stabilization.

Arieh Warshel, Avital Shurki, Marek Strajbl, 2003, Journal of the American Chemical Society.

Discovery and Characterization of Allosteric WNK Kinase Inhibitors.

Z. Deng, Y. Yagi, Mitsunori Kato, 2016, ACS chemical biology.

What are the roles of substrate-assisted catalysis and proximity effects in peptide bond formation by the ribosome?

A. Warshel, P. K. Sharma, Mitsunori Kato, 2005, Biochemistry.

Polarizable Force Fields: History, Test Cases, and Prospects.

Arieh Warshel, Mitsunori Kato, Andrei V. Pisliakov, 2007, Journal of chemical theory and computation.

Using a charging coordinate in studies of ionization induced partial unfolding.

A. Warshel, Mitsunori Kato, 2006, The journal of physical chemistry. B.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu

Eric Therrien, Mitsunori Kato, M. Lawrenz, 2023, J. Chem. Inf. Model..

FOCUS - Development of a Global Communication and Modeling Platform for Applied and Computational Medicinal Chemists

Peter Gedeck, Ruben Abagyan, Maxim Totrov, 2015, J. Chem. Inf. Model..