N. Savery

发表

An Orthogonal Multi-input Integration System to Control Gene Expression in Escherichia coli.

M. di Bernardo, L. Marucci, Fabio Annunziata, 2017, ACS synthetic biology.

A comparative analysis of synthetic genetic oscillators

M. di Bernardo, C. Grierson, N. Savery, 2010, Journal of The Royal Society Interface.

Entrainment and control of bacterial populations; an in silico approach over a spatially extended agent based model

M. Bernardo, K. Tsaneva-Atanasova, N. Savery, 2014 .

Temperature dependence of ssrA-tag mediated protein degradation

Mario di Bernardo, Oliver Purcell, Claire S Grierson, 2012, Journal of Biological Engineering.

Stalled transcription complexes promote DNA repair at a distance

N. Savery, Abigail J. Smith, Nia M Haines, 2014, Proceedings of the National Academy of Sciences.

Gene Transcription: DNA-binding proteins

S. Busby, N. Savery, T. Belyaeva, 1996 .

Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA

N. Savery, T. Strick, J. R. Portman, 2021, Proceedings of the National Academy of Sciences.

Transcription activation at class I FNR-dependent promoters: identification of the activating surface of FNR and the corresponding contact site in the C-terminal domain of the RNA polymerase alpha subunit.

S. Busby, N. Savery, S. Williams, 1997, Nucleic acids research.

Transcription activation at class II CRP-dependent promoters: the role of different activating regions.

S. Busby, N. Savery, V. Rhodius, 1997, Nucleic acids research.

Interactions between the cyclic AMP receptor protein and the alpha subunit of RNA polymerase at the Escherichia coli galactose operon P1 promoter.

N. Fujita, A. Ishihama, S. Busby, 1994, Nucleic acids research.

Mobility Shift Assays

S. Busby, N. Savery, 1998 .

De novo designed peptides for cellular delivery and subcellular localisation

D. Woolfson, B. Höcker, N. Savery, 2022, Nature Chemical Biology.

Protein-Interaction Modules for In-Cell Applications.

Woolfson, N. Savery, Abigail J. Smith, 2020 .

Initiation of transcription-coupled repair characterized at single-molecule resolution

N. Savery, S. Darst, L. Westblade, 2012, Nature.

Reconstruction of bacterial transcription-coupled repair at single-molecule resolution

N. Savery, T. Strick, Jun Fan, 2016, Nature.

Transcription coupled nucleotide excision repair in Escherichia coli can be affected by changing the arginine at position 529 of the beta subunit of RNA polymerase.

P. Hanawalt, N. Savery, A. Ganesan, 2007, DNA repair.

Prioritizing the repair of DNA damage that is encountered by RNA polymerase

N. Savery, 2011, Transcription.

Understanding bias in DNA repair

N. Savery, T. Strick, 2017, Proceedings of the National Academy of Sciences.

A reverse gear for transcription‐coupled DNA repair? (Comment on DOI 10.1002/bies.201400106)

N. Savery, 2015, BioEssays : news and reviews in molecular, cellular and developmental biology.

De novo designed peptides for cellular delivery and subcellular localisation

D. Woolfson, B. Höcker, N. Savery, 2022, Nature Chemical Biology.

From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles

D. Woolfson, D. M. Andrews, O. Weiner, 2022, bioRxiv.

Bacterial gene regulatory proteins: organisation and mechanism of action

S. Busby, N. Savery, V. Rhodius, 1998 .

Protein-protein interactions during transcription activation: the case of the Escherichia coli cyclic AMP receptor protein.

S. Busby, N. Savery, V. Rhodius, 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

D. Wigley, P. McGlynn, N. Savery, 2017, Nucleic acids research.

Assays for transcription factor activity.

Nigel Savery, Douglas Browning, Stephen Busby, 2009, Methods in molecular biology.

Structural Basis for Bacterial Transcription-Coupled DNA Repair

N. Savery, S. Darst, A. Hochschild, 2006, Cell.

RNA polymerase mutants defective in the initiation of transcription-coupled DNA repair

A. Smith, N. Savery, Abigail J. Smith, 2005, Nucleic acids research.

UP element-dependent transcription at the Escherichia coli rrnB P1 promoter: positional requirements and role of the RNA polymerase alpha subunit linker.

R. Gourse, S. Busby, N. Savery, 2001, Nucleic acids research.

The conflict between DNA replication and transcription

P. McGlynn, N. Savery, M. Dillingham, 2012, Molecular microbiology.

Transcription activation at bacterial promoters

S. Busby, N. Savery, 2007 .

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

N. Savery, F. Sobott, M. Dillingham, 2021, bioRxiv.

The molecular mechanism of transcription-coupled DNA repair.

N. Savery, 2007, Trends in microbiology.

The Conserved C-Terminus of the PcrA/UvrD Helicase Interacts Directly with RNA Polymerase

P. McGlynn, N. Savery, C. Guy, 2013, PloS one.

An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd

N. Savery, Kenneth M. Ralto, M. N. Murphy, 2009, Nucleic acids research.

Three Studies in Synthetic Biology

M. Bernardo, K. Edwards, Fabio Annunziata, 2019 .

ChipSeg: An Automatic Tool to Segment Bacterial and Mammalian Cells Cultured in Microfluidic Devices

Mario di Bernardo, Giansimone Perrino, Lucia Marucci, 2020, bioRxiv.

Multipartite control of the DNA translocase, Mfd

N. Savery, Abigail J. Smith, C. Pernstich, 2012, Nucleic acids research.

Regulation and Rate Enhancement during Transcription-Coupled DNA Repair

N. Savery, Abigail J. Smith, Young-In T. Kim, 2010, Molecular cell.

Controlling the motor activity of a transcription-repair coupling factor: autoinhibition and the role of RNA polymerase

N. Savery, M. Szczelkun, Abigail J. Smith, 2007, Nucleic acids research.

The bacterial transcription repair coupling factor.

N. Savery, S. Darst, A. Deaconescu, 2007, Current opinion in structural biology.

Effects of the bacterial transcription-repair coupling factor during transcription of DNA containing non-bulky lesions.

N. Savery, Abigail J. Smith, 2008, DNA repair.

A DNA translocation motif in the bacterial transcription--repair coupling factor, Mfd.

A. Smith, N. Savery, Abigail J. Smith, 2003, Nucleic acids research.

Transcription activation at Class II CRP‐dependent promoters: identification of determinants in the C‐terminal domain of the RNA polymerase α subunit

R. Ebright, R. Gourse, S. Busby, 1998, The EMBO journal.

Characterisation of the Escherichia coli mfd promoter

N. Savery, L. Stanley, 2003, Archives of Microbiology.

BSim 2.0: An Advanced Agent-Based Cell Simulator.

Mario di Bernardo, Lucia Marucci, Gianfranco Fiore, 2017, ACS synthetic biology.

BSim: An Agent-Based Tool for Modeling Bacterial Populations in Systems and Synthetic Biology

Thomas E. Gorochowski, Mario di Bernardo, Claire S. Grierson, 2012, PloS one.

In-Silico Analysis and Implementation of a Multicellular Feedback Control Strategy in a Synthetic Bacterial Consortium.

Mario di Bernardo, Lucia Marucci, Gianfranco Fiore, 2017, ACS synthetic biology.

DNA cleavage and methylation specificity of the single polypeptide restriction–modification enzyme LlaGI

J. Josephsen, N. Savery, M. Szczelkun, 2009, Nucleic acids research.

Guiding Biomolecular Interactions in Cells Using de Novo Protein-Protein Interfaces.

Derek N Woolfson, Nigel J Savery, D. Woolfson, 2019, ACS synthetic biology.

Guiding biomolecular interactions in cells using de novo protein-protein interfaces

D. Woolfson, N. Savery, D. Shoemark, 2018, bioRxiv.

Modelling emergence of oscillations in communicating bacteria: a structured approach from one to many cells

Krasimira Tsaneva-Atanasova, Mario di Bernardo, Nigel J. Savery, 2013, Journal of The Royal Society Interface.

Determinants of the C-Terminal Domain of the Escherichia coli RNA Polymerase α Subunit Important for Transcription at Class I Cyclic AMP Receptor Protein-Dependent Promoters

Mark S. Thomas, R. Ebright, R. Gourse, 2002, Journal of bacteriology.

The Escherichia coli RNA polymerase α subunit linker: length requirements for transcription activation at CRP‐dependent promoters

Mark S. Thomas, S. Busby, N. Savery, 2000, The EMBO journal.

Direct removal of RNA polymerase barriers to replication by accessory replicative helicases

Christian J. Rudolph, P. McGlynn, N. Savery, 2019, Nucleic acids research.

The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair

P. McGlynn, N. Savery, C. Guy, 2009, DNA repair.

Inhibiting translation elongation can aid genome duplication in Escherichia coli

R. G. Lloyd, P. McGlynn, N. Savery, 2016, Nucleic acids research.

Protein-DNA Interactions: A practical approach

N. Savery, A. Kolb, T. Belyaeva, 2000 .

A low cost, open source Turbidostat design for in-vivo control experiments in Synthetic Biology

Lucia Marucci, A. Guarino, M. di Bernardo, 2019, bioRxiv.

A low-cost, open-source Turbidostat design for in-vivo control experiments in Synthetic Biology

Mario di Bernardo, Claire S. Grierson, Lucia Marucci, 2019, IFAC-PapersOnLine.

Spacing requirements for interactions between the C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase and the cAMP receptor protein.

S. Busby, N. Savery, G. Lloyd, 1998, The Biochemical journal.

Rational Design of Phosphorylation-Responsive Coiled Coil-Peptide Assemblies

D. Woolfson, N. Savery, J. L. Beesley, 2023, ACS synthetic biology.

De novo designed protein-interaction modules for in-cell applications.

D. Woolfson, N. Savery, Abigail J. Smith, 2020, ACS synthetic biology.

Cheetah: A Computational Toolkit for Cybergenetic Control.

M. di Bernardo, L. Marucci, T. Gorochowski, 2021, ACS synthetic biology.

A Multi-Functional Synthetic Gene Network: A Frequency Multiplier, Oscillator and Switch

Oliver Purcell, Mario di Bernardo, Claire S. Grierson, 2011, PloS one.

In vivo Feedback Control of an Antithetic Molecular-Titration Motif in Escherichia coli using Microfluidics

L. Postiglione, M. di Bernardo, D. Salzano, 2020, bioRxiv.

Length heterogeneity at conserved sequence block 2 in human mitochondrial DNA acts as a rheostat for RNA polymerase POLRMT activity

N. Savery, M. Szczelkun, Benedict G. Tan, 2016, Nucleic acids research.

Interactions between the Escherichia coli cAMP receptor protein and the C-terminal domain of the alpha subunit of RNA polymerase at class I promoters.

S. Busby, N. Savery, E. C. Law, 1999, The Biochemical journal.

Analysis of interactions between Activating Region 1 of Escherichia coli FNR protein and the C‐terminal domain of the RNA polymerase α subunit: use of alanine scanning and suppression genetics

S. Busby, N. Savery, H. Wing, 2000, Molecular microbiology.

Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology

D. Woolfson, D. M. Andrews, N. Savery, 2023, ACS synthetic biology.

In vivo Feedback Control of an Antithetic Molecular-Titration Motif in Escherichia coli using Microfluidics.

Mario di Bernardo, Claire S. Grierson, Lucia Marucci, 2020, ACS synthetic biology.

Robust de novo designed homotetrameric coiled coils.

D. Woolfson, N. Savery, C. Edgell, 2020, Biochemistry.

Controlling gene expression in microbial populations using a multicellular architecture

L. Marucci, D. Salzano, N. Savery, 2022, IFAC-PapersOnLine.

Design of a multicellular feedback control strategy in a synthetic bacterial consortium

Mario di Bernardo, Claire S. Grierson, Lucia Marucci, 2016, 2016 IEEE 55th Conference on Decision and Control (CDC).

Cheetah: a computational toolkit for cybergenetic control

Thomas E. Gorochowski, Mario di Bernardo, Claire S. Grierson, 2020, bioRxiv.

An Orthogonal Multi-input Integration System to Control Gene Expression in Escherichia coli.

M. di Bernardo, L. Marucci, Fabio Annunziata, 2017, ACS synthetic biology.

(2016). Entrainment and Control of Bacterial Populations: An in Silico Study over a Spatially Extended Agent Based Model. ACS Synthetic Biology , 5 (7), 639–653.

M. Bernardo, K. Tsaneva-Atanasova, N. Savery, 2014 .

In-vivo distributed multicellular control of gene expression in microbial consortia

M. di Bernardo, L. Marucci, D. Salzano, 2024, bioRxiv.

ChipSeg: An Automatic Tool to Segment Bacterial and Mammalian Cells Cultured in Microfluidic Devices

M. di Bernardo, D. di Bernardo, L. Marucci, 2020, ACS omega.

Regulation of promoters by two transcription activators: evidence for a 'simultaneous touching' model.

S. Busby, N. Savery, T. Belyaeva, 1996, Biochemical Society transactions.