A. Soto

发表

Systems biology beyond networks: generating order from disorder through self-organization.

K. Saetzler, C. Sonnenschein, A. Soto, 2011, Seminars in cancer biology.

Endocrine disruptors and reproductive health: The case of bisphenol-A

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2006, Molecular and Cellular Endocrinology.

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.

Laura N. Vandenberg, T. Shioda, D. Jacobs, 2012, Endocrine reviews.

Endocrine-disrupting chemicals: an Endocrine Society scientific statement.

L. Giudice, R. Zoeller, G. Prins, 2009, Endocrine reviews.

Competing views on cancer

Prakash Kulkarni, C. Sonnenschein, A. Soto, 2014, Journal of Biosciences.

Fractal analysis in a systems biology approach to cancer.

A. Giuliani, M. Bizzarri, A. Cucina, 2011, Seminars in cancer biology.

Developmental effects of endocrine-disrupting chemicals in wildlife and humans.

A. Soto, T. Colborn, F. V. vom Saal, 1993, Environmental health perspectives.

Developmental effects of endocrine-disrupting chemicals in wildlife and humans

A. Soto, T. Colborn, F. V. Saal, 1994 .

p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.

C. Sonnenschein, A. Soto, H. Justicia, 1991, Environmental health perspectives.

Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.

H. Leffers, J. Sumpter, N. Olea, 1999 .

Environmental causes of cancer: endocrine disruptors as carcinogens

C. Sonnenschein, A. Soto, 2010, Nature Reviews Endocrinology.

Emergentism as a default: Cancer as a problem of tissue organization

C. Sonnenschein, A. Soto, 2005, Journal of Biosciences.

Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma.

C. Sonnenschein, A. Soto, M. Maffini, 2005, The American journal of pathology.

The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory

C. Sonnenschein, A. Soto, 2011, BioEssays : news and reviews in molecular, cellular and developmental biology.

The society of cells cancer and control of cell proliferation

C. Sonnenschein, A. Soto, 2013 .

The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique

C. Sonnenschein, A. Soto, 2013, Journal of Biosciences.

In search of principles for a Theory of Organisms

G. Longo, C. Sonnenschein, A. Soto, 2015, Journal of Biosciences.

Carcinogenesis explained within the context of a theory of organisms.

C. Sonnenschein, A. Soto, 2016, Progress in biophysics and molecular biology.

From the Century of the Gene to that of the Organism: Introduction to New Theoretical Perspectives

G. Longo, A. Soto, Maël Montévil, 2018 .

The role of estrogens on the proliferation of human breast tumor cells (MCF-7).

C Sonnenschein, C. Sonnenschein, A. Soto, 1985, Journal of steroid biochemistry.

The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants.

C Sonnenschein, Mariana F. Fernández, N. Olea, 1995, Environmental health perspectives.

Quantitative comparisons of in vitro assays for estrogenic activities.

H Fang, D M Sheehan, H. Fang, 2000, Environmental health perspectives.

Hormone replacement therapy, cancer, controversies, and women’s health: historical, epidemiological, biological, clinical, and advocacy perspectives

N. Krieger, K. Dickersin, I. Löwy, 2005, Journal of Epidemiology and Community Health.

Interpreting endocrine disruption from an integrative biology perspective

C. Sonnenschein, A. Soto, B. Rubin, 2009, Molecular and Cellular Endocrinology.

Neoplasia as development gone awry: the role of endocrine disruptors.

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2008, International journal of andrology.

The somatic mutation theory of cancer: growing problems with the paradigm?

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology.

Laura N. Vandenberg, T. Shioda, D. Jacobs, 2013, Reproductive toxicology.

Cancer-causing somatic mutations: they are neither necessary nor sufficient

C. Sonnenschein, A. Soto, 2018 .

Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A.

Laura N. Vandenberg, A. Soto, L. Vandenberg, 2006, Endocrinology.

In Vitro Endocrine Disruptor Screening

C. Sonnenschein, A. Soto, N. Prechtl, 1999 .

Science and policy on endocrine disrupters must not be mixed: a reply to a “common sense” intervention by toxicology journal editors

Laura N. Vandenberg, Olwenn V. Martin, L. Giudice, 2013, Environmental Health.

Estrogenic activity of polychlorinated biphenyls present in human tissue and the environment.

John D Spengler, Ana M Soto, Susan A Korrick, 2006, Environmental science & technology.

Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals.

A. Vinggaard, A. Soto, B. Térouanne, 2004, Environmental health perspectives.

Glycemia Regulation: From Feedback Loops to Organizational Closure

Leonardo Bich, M. Mossio, A. Soto, 2020, Frontiers in Physiology.

Biotransformations of bisphenol A in a mammalian model: answers and new questions raised by low-dose metabolic fate studies in pregnant CD1 mice.

D. Zalko, J. Cravedi, A. Soto, 2002, Environmental health perspectives.

Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.

C. Sonnenschein, A. Soto, J. Szelei, 1997, Endocrinology.

The proliferative effect of "anti-androgens" on the androgen-sensitive human prostate tumor cell line LNCaP.

N. Olea, C. Sonnenschein, A. Soto, 1990, Endocrinology.

The D13S171 marker, misannotated to BRCA2, links the AS3 gene to various cancers.

C. Sonnenschein, A. Soto, P. Geck, 2001, American journal of human genetics.

Alkylphenols and Bisphenol A as Environmental Estrogens

C. Sonnenschein, A. Soto, C. Michaelson, 2001 .

An Integrative Approach Toward Biology, Organisms, and Cancer.

C. Sonnenschein, A. Soto, 2018, Methods in molecular biology.

Cell proliferation of estrogen-sensitive cells: the case for negative control.

C. Sonnenschein, A. Soto, 1987, Endocrine reviews.

Correcting an error. Re: Dr. Harris's response to: Soto AM, Sonnenschein C. 2004. The somatic mutation theory of cancer: growing problems with the paradigm? BioEssays 26: 1097-1107.

C. Sonnenschein, A. Soto, 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.

New insights into fetal mammary gland morphogenesis: differential effects of natural and environmental estrogens

C. Sonnenschein, A. Soto, M. Mikkola, 2017, Scientific Reports.

Over a century of cancer research: Inconvenient truths and promising leads

C. Sonnenschein, A. Soto, 2020, PLoS biology.

Revisiting D.W. Smithers’s “Cancer: An Attack on Cytologism” (1962)

C. Sonnenschein, A. Soto, 2020, Biological Theory.

Misperceptions in cell and cancer biology. What pioneers and followers of cell culture bestowed on these fields

C. Sonnenschein, A. Soto, 2017 .

Estrogens in the wrong place at the wrong time: Fetal BPA exposure and mammary cancer.

C. Sonnenschein, A. Soto, Lucía Speroni, 2015, Reproductive toxicology.

The male mammary gland: a target for the xenoestrogen bisphenol A.

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2013, Reproductive toxicology.

The mouse uterotrophic assay: a reevaluation of its validity in assessing the estrogenicity of bisphenol A.

C. Sonnenschein, A. Soto, C. Michaelson, 2000, Environmental health perspectives.

p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.

C. Sonnenschein, A. Soto, H. Justicia, 1991, Environmental health perspectives.

Development of a marker of estrogenic exposure in human serum.

N. Olea, C. Sonnenschein, A. Soto, 1995, Clinical chemistry.

From evidence of harm to public health policy: is there light at the end of the tunnel? A Commentary on "Update on the health effects of bisphenol A: Overwhelming evidence of harm".

C. Sonnenschein, A. Soto, 2020, Endocrinology.

Pesticides in Human Fat and Serum Samples vs Total Effective Xenoestrogen Burden

N. Olea, C. Sonnenschein, A. Soto, 2006 .

Shining a light on sunscreens.

C. Sonnenschein, A. Soto, 2005, Endocrinology.

Environmental Disruptors of Sex Hormone Action

C. Sonnenschein, A. Soto, C. Markey, 2003 .

Reflections on Bioanalytical Techniques for Detecting Endocrine Disrupting Chemicals

C. Sonnenschein, A. Soto, 2001 .

disrupting chemicals and public health protection : A statement of principles from the Endocrine Society Permalink

N. Skakkebaek, T. Woodruff, A. Soto, 2012 .

Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D

C. Sonnenschein, A. Soto, M. F. Sweeney, 2018, Cancer Cell International.

Evidence of Absence: Estrogenicity Assessment of a New Food-Contact Coating and the Bisphenol Used in Its Synthesis.

C. Sonnenschein, A. Soto, M. Maffini, 2017, Environmental science & technology.

The Case for BPA as an Obesogen: Contributors to the Controversy

A. Soto, B. Rubin, C. Schaeberle, 2019, Front. Endocrinol..

Perinatal BPA exposure alters body weight and composition in a dose specific and sex specific manner: The addition of peripubertal exposure exacerbates adverse effects in female mice.

A. Soto, A. Greenberg, M. Obin, 2017, Reproductive toxicology.

Mechanism of estrogen action on cellular proliferation: evidence for indirect and negative control on cloned breast tumor cells.

C. Sonnenschein, A. Soto, 1984, Biochemical and biophysical research communications.

Control of cell proliferation: evidence for negative control on estrogen-sensitive T47D human breast cancer cells.

C. Sonnenschein, A. Soto, P. Siiteri, 1986, Cancer research.

Reductionism, Organicism, and Causality in the Biomedical Sciences: A Critique

C. Sonnenschein, A. Soto, 2019, Perspectives in biology and medicine.

In Utero Exposure to Bisphenol A Alters the Development and Tissue Organization of the Mouse Mammary Gland1

C. Sonnenschein, A. Soto, E. H. Luque, 2001, Biology of reproduction.

Long-Term Effects of Fetal Exposure to Low Doses of the Xenoestrogen Bisphenol-A in the Female Mouse Genital Tract1

C. Sonnenschein, A. Soto, B. Rubin, 2005, Biology of reproduction.

Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells

C. Sonnenschein, A. Soto, J. Szelei, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

Negative controls of cell proliferation: human prostate cancer cells and androgens.

N. Olea, C. Sonnenschein, A. Soto, 1989, Cancer research.

A plasma-borne specific inhibitor of the proliferation of human estrogen-sensitive breast tumor cells (estrocolyone-I)

C. Sonnenschein, A. Soto, Renée M. Silvia, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Estrogen-sensitive proliferation pattern of cloned Syrian hamster kidney tumor cells.

C. Sonnenschein, A. Soto, J. Bass, 1988, Cancer research.

Estrogenic effect of tamoxifen and its derivatives on the proliferation of MCF7 human breast tumor cells.

C. Sonnenschein, A. Soto, J. T. Papendorp, 1985, Life sciences.

Mechanism of estrogen action: indirect effect of estradiol-17 beta on proliferation of quail oviduct cells.

C. Sonnenschein, A. Soto, C. Laugier, 1983, Proceedings of the National Academy of Sciences of the United States of America.

But ... are estrogens per se growth-promoting hormones?

C. Sonnenschein, A. Soto, 1980, Journal of the National Cancer Institute.

Cell multiplication in metazoans: evidence for negative control of initiation in rat fibroblasts.

C. Sonnenschein, A. Soto, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Paradoxes in Carcinogenesis: There Is Light at the End of That Tunnel!

C. Sonnenschein, A. Soto, 2013, Disruptive science and technology.

In Utero Exposure to Bisphenol A Alters the Development and Tissue Organization of the Mouse Mammary Gland

C. Sonnenschein, A. Soto, E. H. Luque, 2001 .

Methods to screen estrogen-agonists and antagonists.

N. Olea, C. Sonnenschein, A. Soto, 1999, Journal of medicinal food.

Chemical Effects on Breast Development, Function, and Cancer Risk: Existing Knowledge and New Opportunities

Laura N. Vandenberg, L. Birnbaum, S. Christiansen, 2022, Current Environmental Health Reports.

Dynamic Metabolic Disruption in Rats Perinatally Exposed to Low Doses of Bisphenol-A

Nicolas J Cabaton, D. Zalko, F. Jourdan, 2015, PloS one.

Identification and characterization of membrane estrogen receptor from MCF7 estrogen-target cells

C. Sonnenschein, A. Soto, Charles E. Powell, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture.

C. Sonnenschein, A. Soto, J. Wong, 2011, Biomaterials.

Metaphysics: the proverbial elephant in the room

C. Sonnenschein, A. Soto, N. Perret, 2017 .

Perinatal BPA exposure and reproductive axis function in CD-1 mice.

A. Soto, N. Acevedo, B. Rubin, 2018, Reproductive toxicology.

Theoretical approach of ductal morphogenesis

C. Sonnenschein, A. Soto, Maël Montévil, 2016 .

Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.

C. Sonnenschein, A. Soto, M. Maffini, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Estrogen target cells. Establishment of a cell line derived from the rat pituitary tumor MtT/F4.

C. Sonnenschein, A. Soto, J. Colofiore, 1976, Experimental cell research.

A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study

A. Soto, S. Fenton, N. Acevedo, 2019, bioRxiv.

Safeguarding Female Reproductive Health Against Endocrine Disrupting Chemicals—The FREIA Project

E. B. Wedebye, S. Christiansen, A. Soto, 2020, International journal of molecular sciences.

Chapter 10 Characterization of Estrogen-Binding Proteins in Sex Steroid Target Cells Growing in Long-Term Culture

C. Sonnenschein, A. Soto, A. Rosner, 1976 .

Characterization of a plasma membrane-resident albumin-binding protein associated with the proliferation of estrogen-target, serum-sensitive cells

C. Sonnenschein, A. Soto, P. Verroust, 2003, Steroids.

Effects of interaction between estradiol‐17β and progesterone on the proliferation of cloned breast tumor cells (MCF‐7 and T47D)

C. Sonnenschein, A. Soto, R. Schatz, 1985, Journal of cellular physiology.

Estrogen-induced cell multiplication: direct or indirect effect on rat uterine cells?

C. Sonnenschein, A. Soto, R. Schatz, 1984, Endocrinology.

Information, programme, signal: dead metaphors that negate the agency of organisms

C. Sonnenschein, A. Soto, 2020, Interdisciplinary science reviews : ISR.

Endocrine disruptors — putting the mechanistic cart before the phenomenological horse

C. Sonnenschein, A. Soto, 2018, Nature Reviews Endocrinology.

Perinatal Exposure to Environmentally Relevant Levels of Bisphenol A Decreases Fertility and Fecundity in CD-1 Mice

Carlos Sonnenschein, Ana M. Soto, Gregory S. Whitt, 2010, Environmental health perspectives.

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.

Shuk-Mei Ho, Taisen Iguchi, Laura N. Vandenberg, 2007, Reproductive toxicology.

Is information a proper observable for biological organization?

G Longo, P-A Miquel, C Sonnenschein, 2012, Progress in biophysics and molecular biology.

The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells.

C Sonnenschein, C. Sonnenschein, A. Soto, 1994, Environmental health perspectives.

An updated review of environmental estrogen and androgen mimics and antagonists

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 1998, The Journal of Steroid Biochemistry and Molecular Biology.

Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice.

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2005, Endocrinology.

Endocrine disruptors: from Wingspread to environmental developmental biology

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

Emergentism by default: A view from the bench

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2006, Synthese.

Androgenic and estrogenic activity in water bodies receiving cattle feedlot effluent in Eastern Nebraska, USA.

Ana M Soto, Carlos Sonnenschein, Louis J Guillette, 2004, Environmental health perspectives.

An evaluation of evidence for the carcinogenic activity of bisphenol A.

P. Hunt, G. Prins, A. Soto, 2007, Reproductive toxicology.

Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society.

T J Woodruff, A C Gore, R Thomas Zoeller, 2012, Endocrinology.

Estrogenicity of resin-based composites and sealants used in dentistry.

F. Olea-Serrano, N. Olea, P. Perez, 1996, Environmental health perspectives.

Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption.

Ana M Soto, Carlos Sonnenschein, Laura N Vandenberg, 2009, Endocrine reviews.

Prenatal Exposure to Low Doses of Bisphenol A Alters the Periductal Stroma and Glandular Cell Function in the Rat Ventral Prostate1

C. Sonnenschein, A. Soto, E. H. Luque, 2001, Biology of reproduction.

Estrogens, Xenoestrogens, and the Development of Neoplasms

C. Sonnenschein, A. Soto, 2004 .

Environmental endocrine disruptors: Effects on the human male reproductive system

Michael F. Sweeney, C. Sonnenschein, A. Soto, 2015, Reviews in Endocrine and Metabolic Disorders.

A novel pathogenic classification of cancers

C. Sonnenschein, A. Soto, B. Davis, 2014, Cancer Cell International.

Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors

C. Brisken, C. Sonnenschein, A. Soto, 2013, Journal of Mammary Gland Biology and Neoplasia.

The death of the cancer cell.

C. Sonnenschein, A. Soto, 2011, Cancer research.

Theories of carcinogenesis: an emerging perspective.

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2008, Seminars in cancer biology.

Keywords Cancer theories Carcinogenesis Cell proliferation Downward causation Organicism Reductionism

C. Sonnenschein, A. Soto, G. Sonnenschein, 2006 .

On the role of 17 alpha‐estradiol and 17 beta‐estradiol in the proliferation of MCF7 and T47D‐A11 human breast tumor cells

C. Sonnenschein, A. Soto, John T. Papendorp, 1985, Journal of cellular physiology.

From Wingspread to CLARITY: a personal trajectory

C. Sonnenschein, A. Soto, C. Schaeberle, 2021, Nature Reviews Endocrinology.

Characterization of an estrogen-sensitive cell line established from normal rat endometrium.

C. Sonnenschein, A. Soto, R. Farookhi, 1974, Cancer research.

Control of growth of estrogen-sensitive cells: role for alpha-fetoprotein.

C. Sonnenschein, A. Soto, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Age-dependent growth inhibition of estrogen-sensitive rat mammary tumors. Probable role of alpha-fetoprotein.

C. Sonnenschein, A. Soto, A. Ucci, 1980, Journal of the National Cancer Institute.

Growth inhibition of estrogen-sensitive rat mammary tumors. Effect of an alpha-fetoprotein-secreting hepatoma.

C. Sonnenschein, A. Soto, A. Ucci, 1980, Journal of the National Cancer Institute.

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies

R. Zoeller, G. Prins, A. Soto, 2020, Reproductive Toxicology.

APRIN is a unique Pds5 paralog with features of a chromatin regulator in hormonal differentiation

C. Sonnenschein, A. Soto, M. Maffini, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

Control of Cell Proliferation: Is the Default State of Cells Quiescence or Proliferation?

C. Sonnenschein, A. Soto, 2021 .

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

L. Giudice, S. Swan, N. Skakkebaek, 2008, Fertility and sterility.

Endocrine Disruption and the Female

C. Sonnenschein, A. Soto, B. Rubin, 2007 .

The stroma as a crucial target in rat mammary gland carcinogenesis

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2004, Journal of Cell Science.

Estrogen receptor levels in estrogen sensitive cells in culture.

C. Sonnenschein, A. Soto, 1979, Journal of steroid biochemistry.

Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats

B. Kramer, J. Potter, S. Baker, 2009, BMC Cancer.

Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development

T. Shioda, C. Sonnenschein, A. Soto, 2014, PloS one.

A complex 3D human tissue culture system based on mammary stromal cells and silk scaffolds for modeling breast morphogenesis and function.

D. Kaplan, C. Sonnenschein, A. Soto, 2010, Biomaterials.

Are times a' changin' in carcinogenesis?

C. Sonnenschein, A. Soto, 2005, Endocrinology.

A review of the carcinogenic potential of bisphenol A.

G. Prins, A. Soto, R. Keri, 2016, Reproductive toxicology.

Cancer as development gone awry: the case for bisphenol-A as a carcinogen

C. Sonnenschein, A. Soto, B. Rubin, 2011, Journal of Developmental Origins of Health and Disease.

Early Life Exposure to Bisphenol A and Breast Neoplasia

C. Sonnenschein, A. Soto, M. Maffini, 2011 .

Does breast cancer start in the womb?

C. Sonnenschein, A. Soto, L. Vandenberg, 2008, Basic & clinical pharmacology & toxicology.

The mammary gland response to estradiol: Monotonic at the cellular level, non-monotonic at the tissue-level of organization?

Laura N. Vandenberg, Ana M. Soto, A. Soto, 2006, The Journal of Steroid Biochemistry and Molecular Biology.

Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow.

Ana M Soto, Megan K Horton, Louis J Guillette, 2003, Environmental health perspectives.

A novel 3D in vitro culture model to study stromal-epithelial interactions in the mammary gland.

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2008, Tissue engineering. Part C, Methods.

Matrix composition modulates vitamin D3's effects on 3D collagen fiber organization by MCF10A cells.

I. Georgakoudi, C. Sonnenschein, A. Soto, 2021, Tissue engineering. Part A.

3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model.

Yang Zhang, Irene Georgakoudi, Ana M Soto, 2018, Biomaterials.

Modeling mammary organogenesis from biological first principles: Cells and their physical constraints.

Maël Montévil, Ana M Soto, Carlos Sonnenschein, 2016, Progress in biophysics and molecular biology.

From Single Cells to Tissues: Interactions between the Matrix and Human Breast Cells in Real Time

C. Stephen Downes, Irene Georgakoudi, Mael Montevil, 2014, PloS one.

Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model.

Irene Georgakoudi, Ana M Soto, Carlos Sonnenschein, 2014, Tissue engineering. Part C, Methods.

Low-Dose BPA Exposure Alters the Mesenchymal and Epithelial Transcriptomes of the Mouse Fetal Mammary Gland

Nicolas J Cabaton, T. Shioda, C. Sonnenschein, 2013, PloS one.

The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2010, BMC Cancer.

Prenatal Bisphenol A Exposure Induces Preneoplastic Lesions in the Mammary Gland in Wistar Rats

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2006, Environmental health perspectives.

Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.

Ana M Soto, Carlos Sonnenschein, Laura N Vandenberg, 2007, Endocrinology.

Somatic mutation theory of carcinogenesis: Why it should be dropped and replaced

C. Sonnenschein, A. Soto, 2000, Molecular carcinogenesis.

Why systems biology and cancer?

C. Sonnenschein, A. Soto, 2011, Seminars in cancer biology.

Minireview: Endocrine Disruptors: Past Lessons and Future Directions.

Ana M Soto, Carlos Sonnenschein, Louis J Guillette, 2016, Molecular endocrinology.

Low dose effects of bisphenol A

Laura N. Vandenberg, Patricia A Hunt, Ana M Soto, 2013 .

Histological analysis of low dose NMU effects in the rat mammary gland

C. Sonnenschein, A. Soto, M. Maffini, 2009, BMC Cancer.

Preface to "From the century of the genome to the century of the organism: New theoretical approaches".

Denis Noble, Giuseppe Longo, Ana M Soto, 2016, Progress in biophysics and molecular biology.

Cell proliferation in metazoans: negative control mechanisms.

C. Sonnenschein, A. Soto, 1991, Cancer treatment and research.

The biological default state of cell proliferation with variation and motility, a fundamental principle for a theory of organisms.

Giuseppe Longo, Maël Montévil, Ana M Soto, 2016, Progress in biophysics and molecular biology.

Toward a theory of organisms: Three founding principles in search of a useful integration.

Giuseppe Longo, Ana M Soto, Carlos Sonnenschein, 2016, Progress in biophysics and molecular biology.

Evaluating cell matrix mechanics using an integrated nonlinear optical tweezer-confocal imaging system

Mark Cronin-Golomb, Carlos Sonnenschein, Lucia Speroni, 2013, Optics & Photonics - NanoScience + Engineering.

Cancer Metastases: So Close and So Far.

C. Sonnenschein, A. Soto, 2015, Journal of the National Cancer Institute.

Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus

C. Sonnenschein, A. Soto, J. Szelei, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

Is systems biology a promising approach to resolve controversies in cancer research?

C. Sonnenschein, A. Soto, 2012, Cancer Cell International.

Dual regulation of breast tubulogenesis using extracellular matrix composition and stromal cells.

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2012, Tissue engineering. Part A.

The role of collagen reorganization on mammary epithelial morphogenesis in a 3D culture model.

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2010, Biomaterials.

Vitamin D3 constrains estrogen’s effects and influences mammary epithelial organization in 3D cultures

C. Sonnenschein, A. Soto, N. Hasan, 2019, Scientific Reports.

Vitamin D3 regulates estrogen’s action and affects mammary epithelial organization in 3D cultures

C. Sonnenschein, A. Soto, N. Hasan, 2018, bioRxiv.

Title (120 characters or less): Vitamin D3 regulates estrogen’s action and affects mammary epithelial organization in cultures

C. Sonnenschein, A. Soto, N. Hasan, 2018 .

Estrogen induction of progesterone receptor and its relationship to cell multiplication rate in the rat pituitary tumor cell line C29RAP.

C. Sonnenschein, A. Soto, H. Lee, 1981, Endocrinology.

Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer

C. Sonnenschein, A. Soto, J. Szelei, 2000, The Journal of Steroid Biochemistry and Molecular Biology.

Assays to measure estrogen and androgen agonists and antagonists.

C Sonnenschein, F. Olea-Serrano, N. Olea, 1998, Advances in experimental medicine and biology.

The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique

C. Sonnenschein, A. Soto, 2013, Journal of Biosciences.

Developing a marker of exposure to xenoestrogen mixtures in human serum.

C. Sonnenschein, A. Soto, M. F. Luizzi, 1997, Environmental health perspectives.

Bisphenol A alters the development of the rhesus monkey mammary gland

Patricia A Hunt, Ana M Soto, Carlos Sonnenschein, 2012, Proceedings of the National Academy of Sciences.

Perinatal exposure to the xenoestrogen bisphenol-A induces mammary intraductal hyperplasias in adult CD-1 mice.

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2008, Reproductive toxicology.

Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate.

C. Sonnenschein, A. Soto, M. Maffini, 2002, Endocrinology.

Rapid three-dimensional quantification of voxel-wise collagen fiber orientation.

Irene Georgakoudi, Ana M Soto, Carlos Sonnenschein, 2015, Biomedical optics express.

Bisphenol A: Perinatal exposure and body weight

A. Soto, B. Rubin, 2009, Molecular and Cellular Endocrinology.

Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals

H. Leffers, J. Sumpter, N. Olea, 1999, Environmental health perspectives.

Perinatal Bisphenol A Exposure Increases Estrogen Sensitivity of the Mammary Gland in Diverse Mouse Strains

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2007, Environmental health perspectives.

Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2013, Environmental health perspectives.

Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure.

C. Sonnenschein, A. Soto, M. Maffini, 2007, Reproductive toxicology.

Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels.

J. King, A. Soto, B. Rubin, 2001, Environmental health perspectives.

The two faces of janus: sex steroids as mediators of both cell proliferation and cell death.

C Sonnenschein, C. Sonnenschein, A. Soto, 2001, Journal of the National Cancer Institute.

Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone.

Michael J. Schlicht, A. Soto, N. Acevedo, 2023, Toxicology.

Effects of Low Doses of Bisphenol A on the Metabolome of Perinatally Exposed CD-1 Mice

Nicolas J Cabaton, D. Zalko, J. Cravedi, 2013, Environmental health perspectives.

Effects of Low Doses of Bisphenol A on the Metabolome of Perinatally Exposed CD1 Mice

Nicolas J Cabaton, D. Zalko, J. Cravedi, 2013 .

Why Public Health Agencies Cannot Depend on Good Laboratory Practices as a Criterion for Selecting Data: The Case of Bisphenol A

Koji Arizono, Taisen Iguchi, Laura N. Vandenberg, 2008, Environmental health perspectives.

Science and policy on endocrine disrupters must not be mixed : a reply to a “ common sense ” intervention

L. Giudice, J. Toppari, S. Swan, 2015 .

Human serum albumin shares the properties of estrocolyone-I, the inhibitor of the proliferation of estrogen-target cells

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

Strengths and weaknesses of in vitro assays for estrogenic and androgenic activity.

C. Sonnenschein, A. Soto, M. Maffini, 2006, Best practice & research. Clinical endocrinology & metabolism.

Mammalian development in a changing environment: exposure to endocrine disruptors reveals the developmental plasticity of steroid‐hormone target organs

Ana M Soto, Carlos Sonnenschein, C. Sonnenschein, 2003, Evolution & development.

The cancer puzzle: Welcome to organicism.

C. Sonnenschein, A. Soto, 2021, Progress in biophysics and molecular biology.

Why is it that despite signed capitulations, the war on cancer is still on?

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2017 .

Endocrine disruptors: DDT, endocrine disruption and breast cancer

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2015, Nature Reviews Endocrinology.

Unanticipated Trends Stemming from Initial Events in the History of Cell Culture: Vitalism in 2013?

Carlos Sonnenschein, Ana M. Soto, C. Sonnenschein, 2013 .

Response to “In defense of the somatic mutation theory of cancer” DOI: 10.1002/bies.201100022

C. Sonnenschein, A. Soto, 2011, BioEssays : news and reviews in molecular, cellular and developmental biology.

On physicalism and Downward Causation in Developmental and Cancer Biology

C Sonnenschein, C. Sonnenschein, A. Soto, 2008, Acta biotheoretica.

Estrogen induction of progestophilins in rat estrogen-sensitive cells grown in media supplemented with sera from castrated rats and from rats bearing an alpha-fetoprotein-secreting hepatoma.

C. Sonnenschein, A. Soto, P. Siiteri, 1984, Experimental cell research.

Pituitary uterotrophic effect in the estrogen-dependent growth of the rat uterus.

C. Sonnenschein, A. Soto, 1978, Journal of steroid biochemistry.

SAMA: A Method for 3D Morphological Analysis

Maël Montévil, Carlos Sonnenschein, Lucia Speroni, 2016, PloS one.

A Hormone-responsive 3D Culture Model of the Human Mammary Gland Epithelium.

C. Sonnenschein, A. Soto, Lucía Speroni, 2016, Journal of visualized experiments : JoVE.

SAMA : A Method for 3 D Morphological Analysis

C. Sonnenschein, A. Soto, Lucía Speroni, 2016 .

Competing views on cancer

Prakash Kulkarni, C. Sonnenschein, A. Soto, 2014, Journal of Biosciences.

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research.

Laura N. Vandenberg, Patricia A Hunt, Cheryl S Watson, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Regulation of Cell Proliferation: The Negative Control Perspective a

C Sonnenschein, C. Sonnenschein, A. Soto, 1991, Annals of the New York Academy of Sciences.

Importance of dosage standardization for interpreting transcriptomal signature profiles: Evidence from studies of xenoestrogens

K. Coser, J. Chesnes, J. Hur, 2006, Proceedings of the National Academy of Sciences.

Preadipocytes stimulate ductal morphogenesis and functional differentiation of human mammary epithelial cells on 3D silk scaffolds.

D. Kaplan, C. Sonnenschein, A. Soto, 2009, Tissue engineering. Part A.

Breast epithelial tissue morphology is affected in 3D cultures by species-specific collagen-based extracellular matrix.

C. Sonnenschein, A. Soto, Eugen Dhimolea, 2012, Journal of biomedical materials research. Part A.

Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats

C. Sonnenschein, A. Soto, M. Maffini, 2008, Cancer Cell International.

Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D

Michael F. Sweeney, C. Sonnenschein, A. Soto, 2018, Cancer Cell International.

Biological effects of sex hormone-binding globulin on androgen-induced proliferation and androgen metabolism in LNCaP prostate cells.

C. Sonnenschein, A. Soto, D. Damassa, 1991, Endocrinology.

Predictive Value of the Uterotrophic Assay for Genistein Carcinogenicity in the Neonatal Mouse: Relevance to Infants Consuming Soy-Based Formula

C. Sonnenschein, A. Soto, C. Michaelson, 2001 .

Why do we need theories?

Giuseppe Longo, Ana M Soto, G. Longo, 2016, Progress in biophysics and molecular biology.

Variants of the human prostate LNCaP cell line as tools to study discrete components of the androgen-mediated proliferative response.

N. Olea, C. Sonnenschein, A. Soto, 1995, Oncology research.

Bisphenol A Exposure Disrupts Neurotransmitters Through Modulation of Transaminase Activity in the Brain of Rodents.

Fabien Jourdan, Ana M Soto, Cecile Canlet, 2016, Endocrinology.

p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.

C. Sonnenschein, A. Soto, H. Justicia, 1991, Environmental health perspectives.

Late lessons from early warnings: science, precaution, innovation

P. Grandjean, T. Tsuda, S. Hove, 2013 .

Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society.

R. Zoeller, T. Woodruff, N. Skakkebæk, 2012, Endocrinology.

Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption.

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2009, Endocrine reviews.

A novel 3D in vitro culture model to study stromal-epithelial interactions in the mammary gland.

C. Sonnenschein, A. Soto, M. Maffini, 2008, Tissue engineering. Part C, Methods.

The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells.

C. Sonnenschein, A. Soto, K. L. Chung, 1994, Environmental health perspectives.

Correcting an error

C. Sonnenschein, A. Soto, 2006 .

Developmental effects of endocrine-disrupting chemicals in wildlife and humans.

A. Soto, T. Colborn, F. Saal, 1993, Environmental health perspectives.

Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model.

I. Georgakoudi, G. S. Whitt, C. Sonnenschein, 2014, Tissue engineering. Part C, Methods.

Does breast cancer start in the womb?

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2008, Basic & clinical pharmacology & toxicology.

Vitamin D3 constrains estrogen’s effects and influences mammary epithelial organization in 3D cultures

C. Sonnenschein, A. Soto, Nafis Hasan, 2019, Scientific Reports.

Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.

Laura N. Vandenberg, C. Sonnenschein, A. Soto, 2007, Endocrinology.

Why systems biology and cancer?

C. Sonnenschein, A. Soto, 2011, Seminars in cancer biology.

Carcinogenesis and metastasis now in the third dimension--what's in it for pathologists?

C. Sonnenschein, A. Soto, 2006, The American journal of pathology.

Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow.

L. Gray, A. Soto, L. Guillette, 2003, Environmental health perspectives.

Systems biology and cancer.

D. Noble, P. Maini, C. Sonnenschein, 2011, Progress in biophysics and molecular biology.

Forum: Artificial Intelligence, Artificial Agency and Artificial Life

Kenneth Payne, Ana M Soto, Raymond Noble, 2019, The RUSI Journal.

3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model.

C. Alonzo, I. Georgakoudi, C. Sonnenschein, 2018, Biomaterials.

European Medicines Agency Conflicts With the European Food Safety Authority (EFSA) on Bisphenol A Regulation

P. Hunt, L. Birnbaum, A. Kortenkamp, 2023, Journal of the Endocrine Society.

Evidence of Absence: Estrogenicity Assessment of a New Food-Contact Coating and the Bisphenol Used in Its Synthesis.

C. Sonnenschein, A. Soto, M. Maffini, 2017, Environmental science & technology.

Is systems biology a promising approach to resolve controversies in cancer research?

C. Sonnenschein, A. Soto, 2012, Cancer Cell International.

[Endocrine disruptors: a very personal story with multiple personalities].

C. Sonnenschein, A. Soto, 2002, Gaceta sanitaria.