P. Portincasa

发表

(13)C-octanoic acid breath test (OBT) with a new test meal (EXPIROGer): Toward standardization for testing gastric emptying of solids.

F. Perri, M. Bellini, P. Portincasa, 2010, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Biochemical mechanisms in drug-induced liver injury: certainties and doubts.

Ignazio Grattagliano, Piero Portincasa, P. Portincasa, 2009, World journal of gastroenterology.

Upper Endoscopy in Patients with Extra-Oesophageal Reflux Symptoms: A Multicentre Study

A. Zullo, P. Portincasa, G. Bassotti, 2020, GE - Portuguese Journal of Gastroenterology.

Gaining Back What Is Lost: Recovering the Sense of Smell in Mild to Moderate Patients After COVID-19

P. Portincasa, N. Quaranta, M. Gelardi, 2020, Chemical senses.

Synergistic and Detrimental Effects of Alcohol Intake on Progression of Liver Steatosis

M. Krawczyk, G. Frühbeck, P. Portincasa, 2022, International journal of molecular sciences.

Oxidative and Nitrosative Stress in Chronic Cholestasis

P. Portincasa, P. Oliveira, I. Grattagliano, 2017 .

Oxidized LDL Receptor 1 gene polymorphism in patients with Metabolic Syndrome

P. Portincasa, I. Grattagliano, G. Palasciano, 2013, European journal of clinical investigation.

Red blood cells (RBC) deformability and aggregability: alterations in alcoholism.

P. Portincasa, I. Grattagliano, G. Palasciano, 2006, Advances in experimental medicine and biology.

Update on pathological platelet activation in coronary thrombosis

P. Portincasa, F. Montecucco, F. Carbone, 2018, Journal of cellular physiology.

A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes.

P. Portincasa, P. Oliveira, I. Grattagliano, 2013, World journal of gastroenterology.

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease.

G. Frühbeck, P. Portincasa, P. Oliveira, 2019, Biochemical pharmacology.

New insights into the role of Lith genes in the formation of cholesterol-supersaturated bile

B. Neuschwander‐Tetri, P. Portincasa, D. Ford, 2017, Liver research.

Molecular pathophysiology and physical chemistry of cholesterol gallstones.

P. Portincasa, Helen H. Wang, D. Q. Wang, 2008, Frontiers in Bioscience.

Relevance of hereditary defects in lipid transport proteins for the pathogenesis of cholesterol gallstone disease

P. Portincasa, A. Groen, A. Kosters, 2004, Scandinavian journal of gastroenterology. Supplement.

Impact of Endocrine Disorders on the Liver

F. Lammert, M. Krawczyk, P. Portincasa, 2020, Endocrinology.

Impact of Endocrine Disorders on the Liver

F. Lammert, M. Krawczyk, P. Portincasa, 2020, Endocrinology.

Improvement of MEFV gene variants classification to aid treatment decision making in familial Mediterranean fever

M. Accetturo, P. Portincasa, A. M. D’Uggento, 2019, Rheumatology.

The grandfather’s fever

P. Portincasa, A. Stella, G. Scaccianoce, 2019, Clinical Rheumatology.

A novel cluster of patients with Familial Mediterranean Fever (FMF) in southern Italy

E. Ben-Chetrit, P. Portincasa, G. Palasciano, 2017, European journal of clinical investigation.

Novel Therapeutics for the Treatment of Familial Mediterranean Fever: From Colchicine to Biologics

P. Portincasa, I. Grattagliano, V. Ruggiero, 2013, Clinical pharmacology and therapeutics.

Familial Mediterranean Fever: From Pathogenesis to Treatment

P. Portincasa, L. Bonfrate, D. Wang, 2014 .

Familial mediterranean fever: a fascinating model of inherited autoinflammatory disorder

P. Portincasa, G. Palasciano, G. Scaccianoce, 2013, European journal of clinical investigation.

Increased Colonic Permeability and Lifestyles as Contributing Factors to Obesity and Liver Steatosis

P. Portincasa, G. Garruti, M. De Angelis, 2020, Nutrients.

Familial Mediterranean Fever and COVID-19: Friends or Foes?

P. Portincasa, M. Lamkanfi, A. Stella, 2020, Frontiers in Immunology.

Hereditary Nephrogenic Diabetes Insipidus: Molecular Basis of the Defect and Potential Novel Strategies for Treatment

P. Portincasa, M. Svelto, L. Bonfrate, 2014 .

Nitrogen dioxide pollution increases vulnerability to COVID-19 through altered immune function

A. Dell'Acqua, P. Portincasa, F. Fiermonte, 2022, Environmental Science and Pollution Research.

Comment: Esomeprazole-Induced Central Fever with Severe Myalgia

P. Portincasa, I. Grattagliano, S. Su, 2005, The Annals of pharmacotherapy.

The dangerous link between childhood and adulthood predictors of obesity and metabolic syndrome

Piero Portincasa, G. Frühbeck, P. Portincasa, 2016, Internal and Emergency Medicine.

Time to Consider the “Exposome Hypothesis” in the Development of the Obesity Pandemic

G. Frühbeck, P. Portincasa, V. Catalán, 2022, Nutrients.

Bile Acids and GPBAR-1: Dynamic Interaction Involving Genes, Environment and Gut Microbiome

P. Portincasa, G. Garruti, M. De Angelis, 2020, Nutrients.

Cross-Talk Between Bile Acids and Gastro-Intestinal and Thermogenic Hormones: Clues from Bariatric Surgery

P. Portincasa, G. Garruti, Helen H. Wang, 2017, Annals of hepatology.

Experimental observations and clinical implications of fasting and diet supplementation in fatty livers.

P. Portincasa, P. Caraceni, I. Grattagliano, 2003, European review for medical and pharmacological sciences.

Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin.

P. Portincasa, I. Grattagliano, G. Paradies, 2007, Biochimica et biophysica acta.

Interleukins 1 beta and 6 induce functional alteration of rat colonic motility: an in vitro study

P. Portincasa, A. Moschetta, A. Marzullo, 2003, European journal of clinical investigation.

Chocolate, “Food of the Gods”: History, Science, and Human Health

P. Portincasa, M. Montagna, G. Diella, 2019, International journal of environmental research and public health.

Non-alcoholic fatty liver disease in non-obese individuals: Prevalence, pathogenesis and treatment.

F. Lammert, M. Krawczyk, P. Portincasa, 2019, Clinics and research in hepatology and gastroenterology.

Intestinal absorption, hepatic synthesis, and biliary secretion of cholesterol: Where are we for cholesterol gallstone formation?

P. Portincasa, David Q.‐H. Wang, 2012, Hepatology.

Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease

S. Costanzo, L. Iacoviello, C. Cerletti, 2019, British Journal of Nutrition.

Unraveling the beneficial effects of herbal Lebanese mixture “Za’atar”. History, studies, and properties of a potential healthy food ingredient

P. Portincasa, L. Vergani, M. De Angelis, 2022, Journal of Functional Foods.

Chemical Characterization, Gastrointestinal Motility and Sensory Evaluation of Dark Chocolate: A Nutraceutical Boosting Consumers’ Health

A. Logrieco, P. Portincasa, M. Lorusso, 2020, Nutrients.

A systematic review and meta-analysis of the role of Helicobacter pylori eradication in preventing gastric cancer

P. Portincasa, T. Rokkas, Androniki Rokka, 2017, Annals of gastroenterology.

Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.

P. Portincasa, I. Grattagliano, G. Palasciano, 2006, Clinical science.

Physical Activity Modulating Lipid Metabolism in Gallbladder Diseases.

P. Portincasa, G. Garruti, M. Faienza, 2020, Journal of gastrointestinal and liver diseases : JGLD.

Beneficial effects of oral tilactase on patients with hypolactasia

P. Portincasa, G. Palasciano, A. Di Ciaula, 2008, European journal of clinical investigation.

Altered distribution of caveolin‐1 in early liver steatosis

G. Calamita, P. Portincasa, M. Mastrodonato, 2011, European journal of clinical investigation.

Fecal calprotectin in assessing inflammatory bowel disease endoscopic activity: a diagnostic accuracy meta-analysis.

P. Portincasa, T. Rokkas, I. Koutroubakis, 2018, Journal of gastrointestinal and liver diseases : JGLD.

Methodology and Indications of H2‐Breath Testing in Gastrointestinal Diseases: the Rome Consensus Conference

A. Gasbarrini, G. Corazza, F. Perri, 2009, Alimentary pharmacology & therapeutics.

Relationship between Liver Stiffness and Steatosis in Obesity Conditions: In Vivo and In Vitro Studies

A. Bartolozzi, M. Vassalli, P. Portincasa, 2022, Biomolecules.

Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease – a double‐blind, randomised, placebo‐controlled study

P. Portincasa, A. Tursi, S. Danese, 2013, Alimentary pharmacology & therapeutics.

The Involvement of Human Papilloma Virus in Gastrointestinal Cancers

M. Dobrzynski, P. Portincasa, J. Flieger, 2022, Cancers.

Modifiable Factors and Genetic Predisposition Associated with Gallbladder Cancer. A Concise Review.

M. Krawczyk, P. Portincasa, P. Milkiewicz, 2015, Journal of gastrointestinal and liver diseases : JGLD.

Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin.

P. Portincasa, L. Vergani, P. Oliveira, 2019, International journal of molecular medicine.

Polyphenolic extract attenuates fatty acid-induced steatosis and oxidative stress in hepatic and endothelial cells

B. Aliakbarian, P. Portincasa, L. Vergani, 2018, European Journal of Nutrition.

Eradication rates in Italian subjects heterogeneously managed for Helicobacter pylori infection. Time to abandon empiric treatments in Southern Europe.

A. Zullo, P. Portincasa, T. Rokkas, 2017, Journal of gastrointestinal and liver diseases : JGLD.

Clinical and Metabolomic Effects of Lactiplantibacillus plantarum and Pediococcus acidilactici in Fructose Intolerant Patients

G. Celano, P. Portincasa, D. Dumitrascu, 2022, Nutrients.

Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients

G. Celano, P. Portincasa, M. Gobbetti, 2020, European journal of clinical investigation.

Oxidative stress in symptom‐free HCV carriers: relation with ALT flare‐up

P. Portincasa, I. Grattagliano, G. Vendemiale, 2001, European journal of clinical investigation.

The role of microbiota in nonalcoholic fatty liver disease

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2022, European journal of clinical investigation.

The Cardiovascular Disease (CVD) Risk Continuum from Prenatal Life to Adulthood: A Literature Review

P. Portincasa, P. Giordano, G. Lassandro, 2022, International journal of environmental research and public health.

Increase of the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes after Roux-en-Y Gastric Bypass

G. Frühbeck, P. Portincasa, V. Catalán, 2019, Nutrients.

Colon neoplasia in patients with type 2 diabetes on metformin: A meta-analysis.

P. Portincasa, T. Rokkas, Theodore Rokkas, 2016, European journal of internal medicine.

Endocrinology and Systemic Diseases

H. Nathoe, G. Frühbeck, P. Portincasa, 2020, Endocrinology.

The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice.

P. Portincasa, Helen H. Wang, Helen H Wang, 2015, Biochimica et biophysica acta.

Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice

P. Portincasa, Min Liu, O. de Bari, 2015, Journal of Lipid Research.

Ezetimibe prevents the formation of oestrogen‐induced cholesterol gallstones in mice

P. Portincasa, C. Paik, Helen H. Wang, 2014, European journal of clinical investigation.

Gallstone prevalence and gallbladder volume in children and adolescents: an epidemiological ultrasonographic survey and relationship to body mass index.

A. Velardi, P. Portincasa, G. Palasciano, 1989, The American journal of gastroenterology.

In situ characterization of O-linked glycans of Muc2 in mouse colon.

P. Portincasa, S. Desantis, M. Mastrodonato, 2012, Acta histochemica.

Indomethacin Enhances Bile Salt Detergent Activity: Relevance for NSAIDs-Induced Gastrointestinal Mucosal Injury

P. Portincasa, A. Moschetta, W. Renooij, 2006, Digestive Diseases and Sciences.

High-fat diet alters the oligosaccharide chains of colon mucins in mice

G. Calamita, P. Portincasa, M. Mastrodonato, 2014, Histochemistry and Cell Biology.

Gallbladder volume in adults, and relationship to age, sex, body mass index, and gallstones: a sonographic population study.

G. Serio, A. Velardi, P. Portincasa, 1992, The American journal of gastroenterology.

Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol

B. Neuschwander‐Tetri, P. Portincasa, G. Garruti, 2013, European journal of clinical investigation.

Ezetimibe: Its Novel Effects on the Prevention and the Treatment of Cholesterol Gallstones and Nonalcoholic Fatty Liver Disease

B. Neuschwander‐Tetri, P. Portincasa, Min Liu, 2011, Journal of lipids.

Genetic Analysis of ABCB4 Mutations and Variants Related to the Pathogenesis and Pathophysiology of Low Phospholipid-Associated Cholelithiasis

P. Portincasa, Helen H. Wang, Helen H Wang, 2022, Genes.

Functional Relationship between Leptin and Nitric Oxide in Metabolism

G. Frühbeck, P. Portincasa, V. Catalán, 2019, Nutrients.

Circulating CRP Levels Are Associated with Epicardial and Visceral Fat Depots in Women with Metabolic Syndrome Criteria

P. Portincasa, F. Montecucco, F. Carbone, 2019, International journal of molecular sciences.

Gallbladder volume and emptying in diabetics: the role of neuropathy and obesity

R. Giorgino, P. Portincasa, M. Cignarelli, 1992, Journal of internal medicine.

Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile

P. Portincasa, K. V. van Erpecum, W. Renooij, 1996, European journal of clinical investigation.

Adipocyte hypertrophy parallels alterations of mitochondrial status in a cell model for adipose tissue dysfunction in obesity.

H. Zischka, P. Portincasa, L. Vergani, 2020, Life sciences.

Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation

G. Frühbeck, P. Portincasa, V. Catalán, 2017, Scientific Reports.

Oxidative stress, aging, antioxidant supplementation and their impact on human health: An overview

P. Portincasa, A. Ciaula, A. D’Alessandro, 2022, Mechanisms of Ageing and Development.

Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells.

P. Portincasa, L. Vergani, I. Grattagliano, 2016, World journal of gastroenterology.

Improving nonalcoholic fatty liver disease management by general practitioners: a critical evaluation and impact of an educational training program.

P. Portincasa, A. Moschetta, I. Grattagliano, 2008, Journal of gastrointestinal and liver diseases : JGLD.

Severe liver steatosis correlates with nitrosative and oxidative stress in rats

G. Calamita, P. Portincasa, P. Caraceni, 2008, European journal of clinical investigation.

Anti‐ApoA‐1 IgGs predict resistance to waist circumference reduction after Mediterranean diet

P. Portincasa, S. Pagano, F. Montecucco, 2020, European journal of clinical investigation.

Relationships between Obstructive Sleep Apnea Syndrome and cardiovascular risk in a naïve population of southern Italy

O. Resta, P. Portincasa, S. Dragonieri, 2021, International journal of clinical practice.

Malignant hypertension and hyperreninemia: primary or secondary hypertension? A case report

P. Portincasa, V. Palmieri, A. Belfiore, 2021 .

Biomarkers and Genetic Markers of Hepatocellular Carcinoma and Cholangiocarcinoma—What Do We Already Know

P. Portincasa, M. Furtak-Niczyporuk, J. Flieger, 2022, Cancers.

Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function Published, JLR Papers in Press, October 13, 2005.

G. Calamita, P. Portincasa, A. Moschetta, 2006, Journal of Lipid Research.

An update on the pathogenesis of cholesterol gallstone disease

P. Portincasa, A. Di Ciaula, D. Q. Wang, 2017, Current opinion in gastroenterology.

Smooth muscle function and dysfunction in gallbladder disease

P. Portincasa, A. Ciaula, G. P. vanBerge-Henegouwen, 2004, Current gastroenterology reports.

The nuclear hormone receptor ERα plays a critical role in determining estrogen-induced cholesterol gallstones

P. Portincasa, D. Q. Wang, H. H. Wang, 2009 .

Targeting the liver in the metabolic syndrome: evidence from animal models.

P. Portincasa, A. Moschetta, G. Lo Sasso, 2007, Current pharmaceutical design.

Sphingomyelin Protects Against Apoptosis and Hyperproliferation Induced by Deoxycholate: Potential Implications for Colon Cancer

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2003, Digestive Diseases and Sciences.

FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes.

G. Frühbeck, P. Portincasa, V. Catalán, 2020, Metabolism: clinical and experimental.

Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats

P. Portincasa, A. Moschetta, I. Grattagliano, 2004, Experimental Gerontology.

Bile Formation and Pathophysiology of Gallstones

P. Portincasa, Helen H. Wang, Helen H Wang, 2019 .

Cholecystectomy: a way forward and back to metabolic syndrome?

P. Portincasa, G. Garruti, A. Di Ciaula, 2018, Laboratory Investigation.

Lack of endogenous cholecystokinin promotes cholelithogenesis in mice

P. Portincasa, P. Tso, Min Liu, 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Symptoms and diagnosis of gallbladder stones

P. Portincasa, A. Moschetta, A. Ciaula, 2006 .

Activation of Estrogen Receptor G Protein–Coupled Receptor 30 Enhances Cholesterol Cholelithogenesis in Female Mice

P. Portincasa, Helen H. Wang, Helen H Wang, 2020, Hepatology.

Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones.

P. Portincasa, M. Uribe, N. Méndez-Sánchez, 2008, Gastroenterology.

The Potential of the Mediterranean Diet to Improve Mitochondrial Function in Experimental Models of Obesity and Metabolic Syndrome

G. Frühbeck, P. Portincasa, J. Gómez-Ambrosi, 2022, Nutrients.

Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome.

A. Zhernakova, M. Netea, M. Camilleri, 2018, Gastroenterology.

Cholesterol saturation rather than phospholipid/bile salt ratio or protein content affects crystallization sequences in human gallbladder bile

P. Portincasa, K. V. van Erpecum, N. Venneman, 2004, European journal of clinical investigation.

The role of dietary approach in irritable bowel syndrome.

G. Calamita, P. Portincasa, O. de Bari, 2019, Current medicinal chemistry.

The two congested failing giants: heart and liver

P. Portincasa, 2019, Internal and Emergency Medicine.

Increased Prevalence of Rare Sucrase-isomaltase (SI) Pathogenic Variants in Irritable Bowel Syndrome Patients

W. Chey, M. Camilleri, G. Boeckxstaens, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Bile Acid Physiology.

P. Portincasa, G. Garruti, L. Bonfrate, 2017, Annals of hepatology.

The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: a multicenter study.

P. Portincasa, F. Basile, A. Biondi, 2007, Transplantation proceedings.

[Efficacy and tolerability of cinitapride in the treatment of functional dyspepsia and delayed gastric emptying].

P. Portincasa, F. Mearin, J. Heras, 2009, Gastroenterologia y hepatologia.

Pathogenic role of oxidative and nitrosative stress in primary biliary cirrhosis.

G. Calamita, P. Portincasa, I. Grattagliano, 2014, World journal of gastroenterology.

Long-term ursodeoxycholate improves circulating redox changes in primary biliary cirrhotic patients.

P. Portincasa, I. Grattagliano, G. Palasciano, 2011, Clinical biochemistry.

Mutual changes of thioredoxin and nitrosothiols during biliary cirrhosis: Results from humans and cholestatic rats

P. Portincasa, I. Grattagliano, G. Palasciano, 2007, Hepatology.

Breath tests with novel 13C-substrates for clinical studies of liver mitochondrial function in health and disease.

A. Ascensão, A. Buzoianu, P. Portincasa, 2013, European review for medical and pharmacological sciences.

Chronic Ethanol Administration Induces Oxidative Alterations and Functional Impairment of Pancreatic Mitochondria in the Rat

P. Portincasa, I. Grattagliano, G. Palasciano, 1999, Digestion.

Familial Mediterranean fever: breaking all the (genetic) rules

P. Portincasa, B. Pivetta, A. Stella, 2018, Rheumatology.

Longer Walking Distance, More Fat, Better Survival: Prognostic Indicators of Liver Cirrhosis.

P. Portincasa, A. Di Ciaula, D. Q. Wang, 2021, Journal of gastrointestinal and liver diseases : JGLD.

The unsolved mystery of MEFV variants variable expressivity in Familial Mediterranean Fever

P. Portincasa, A. Stella, 2022, Internal and Emergency Medicine.

Comment on: Improvement of MEFV gene variants classification to aid treatment decision making in familial Mediterranean fever-reply.

P. Portincasa, A. Stella, 2019, Rheumatology.

‘Obesities’: Position statement on a complex disease entity with multifaceted drivers

G. Frühbeck, P. Portincasa, Camilo Silva, 2022, European journal of clinical investigation.

Mitochondrial oxidative damage and myocardial fibrosis in rats chronically intoxicated with moderate doses of ethanol.

P. Portincasa, I. Grattagliano, G. Palasciano, 2001, Toxicology letters.

Influence of Simulated In Vitro Gastrointestinal Digestion on the Phenolic Profile, Antioxidant, and Biological Activity of Thymbra spicata L. Extracts

G. Damonte, P. Portincasa, L. Vergani, 2022, Antioxidants.

Overview on the mechanisms of drug-induced liver cell death.

P. Portincasa, I. Grattagliano, G. Palasciano, 2002, Annals of hepatology.

Indomethacin‐induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model

P. Portincasa, I. Grattagliano, A. Marzullo, 2005, European journal of clinical investigation.

Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

P. Portincasa, G. Garruti, R. Maciejewski, 2020, Cells.

Effects of long-term orall-arginine on esophageal motility and gallbladder dynamics in healthy humans.

B. Weusten, R. van der Meer, P. Portincasa, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Effects of long-term oral L-arginine on esophageal motility and gallbladder dynamics in healthy humans.

B. Weusten, R. van der Meer, P. Portincasa, 1998, The American journal of physiology.

Research update for articles published in EJCI in 2017

N. Goswami, G. Ndrepepa, C. Schernthaner, 2019, European journal of clinical investigation.

Helicobacter pylori infection: association with dietary habits and socioeconomic conditions.

P. Trerotoli, P. Portincasa, E. Ierardi, 2019, Clinics and research in hepatology and gastroenterology.

Caveolin‐1 and mitochondrial alterations in regenerating rat liver

P. Portincasa, M. Mastrodonato, L. Resta, 2012, Microscopy research and technique.

Parallel intestinal and liver injury during early cholestasis in the rat: modulation by bile salts and antioxidants.

M. Vacca, G. Calamita, P. Portincasa, 2007, Free radical biology & medicine.

Adaptation of subcellular glutathione detoxification system to stress conditions in choline-deficient diet induced rat fatty liver

P. Portincasa, F. Trevisani, P. Caraceni, 2003, Cell Biology and Toxicology.

Mitochondrial glutathione content determines the rate of liver regeneration after partial hepatectomy in eu- and hypothyroid rats.

P. Portincasa, M. Caruso, A. Valentini, 2003, Journal of hepatology.

Application of a Decision Tree Model to Predict the Outcome of Non-Intensive Inpatients Hospitalized for COVID-19

P. Trerotoli, P. Portincasa, M. Montagna, 2022, International journal of environmental research and public health.

Novel insights into the pathogenic impact of diabetes on the gastrointestinal tract

G. Frühbeck, P. Portincasa, G. Garruti, 2022, European journal of clinical investigation.

Cholesterol gallstone disease

P. Portincasa, A. Moschetta, G. Palasciano, 2006, The Lancet.

An Update on the Lithogenic Mechanisms of Cholecystokinin a Receptor (CCKAR), an Important Gallstone Gene for Lith13

P. Portincasa, P. Tso, Helen H. Wang, 2020, Genes.

Update on the Molecular Mechanisms Underlying the Effect of Cholecystokinin and Cholecystokinin-1 Receptor on the Formation of Cholesterol Gallstones.

P. Portincasa, Helen H. Wang, Helen H Wang, 2019, Current medicinal chemistry.

Gallbladder Disease: Relevance of Oxidative Stress

P. Portincasa, I. Grattagliano, Saverio A. Ciampi, 2017 .

Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice.

P. Portincasa, P. Tso, L. Samuelson, 2010, Biochimica et biophysica acta.

Biliary proteins and their redox status changes in gallstone patients

P. Portincasa, I. Grattagliano, A. Ciaula, 2009, European journal of clinical investigation.

Water handling and aquaporins in bile formation: recent advances and research trends.

G. Calamita, P. Portincasa, A. Moschetta, 2003, Journal of hepatology.

Measurements of gallbladder motor function by ultrasonography: towards standardization.

P. Portincasa, A. Moschetta, A. Colecchia, 2003, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Cholesterol crystallization in model biles: effects of bile salt and phospholipid species composition.

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2001, Journal of lipid research.

Review article: agents affecting gall‐bladder motility – role in treatment and prevention of gallstones

P. Portincasa, K. V. van Erpecum, N. Venneman, 2000, Alimentary pharmacology & therapeutics.

Apolipoprotein E4 genotype and gallbladder motility influence speed of gallstone clearance and risk of recurrence after extracorporeal shock‐wave lithotripsy

P. Portincasa, T. D. de Bruin, K. V. van Erpecum, 1996, Hepatology.

Behavior of various cholesterol crystals in bile from patients with gallstones

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 1996, Hepatology.

Gallbladder motor function in gallstone patients: sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation.

P. Portincasa, G. Palasciano, A. Cimmino, 1994, Journal of hepatology.

Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice

G. Calamita, G. Frühbeck, P. Portincasa, 2015, Scientific Reports.

Altered membrane glycoprotein targeting in cholestatic hepatocytes

G. Calamita, P. Portincasa, M. Mastrodonato, 2010, European journal of clinical investigation.

Alteredmembraneglycoproteintargetingin cholestatic hepatocytes

G. Calamita, P. Portincasa, M. Mastrodonato, 2010 .

Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.

P. Portincasa, I. Grattagliano, C. Marulli, 2013, Annals of hepatology.

The Potential of Lamiaceae Herbs for Mitigation of Overweight, Obesity, and Fatty Liver: Studies and Perspectives

L. Vergani, P. Portincasa, Francesca Baldini, 2022, Molecules.

Incorporation of cholesterol in sphingomyelin- phosphatidylcholine vesicles has profound effects on detergent-induced phase transitions DOI 10.1194/jlr.M100355-JLR200

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2002, Journal of Lipid Research.

INCORPORATION OF CHOLESTEROL IN SPHINGOMYELIN- EGG YOLK PHOSPHATIDYLCHOLINE VESICLES HAS PROFOUND EFFECTS ON DETERGENT-INDUCED PHASE TRANSITIONS: A TIME-COURSE STUDY BY CRYO-TRANSMISSION ELECTRON MICROSCOPY

P. Portincasa, P. Frederik, K. Erpecum, 2002 .

Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo.

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2001, Journal of hepatology.

Non-alcoholic steatohepatitis (NASH): approaching more tailored and effective therapies.

P. Portincasa, 2007, Journal of gastrointestinal and liver diseases : JGLD.

A paradigm shift in bariatric surgery outcome evaluation?

G. Frühbeck, P. Portincasa, X. Unamuno, 2019, The lancet. Diabetes & endocrinology.

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Mitochondrial Transport in Glycolysis and Gluconeogenesis: Achievements and Perspectives

P. Portincasa, S. Passarella, A. Schurr, 2021, International journal of molecular sciences.

Glutathione peroxidase, thioredoxin, and membrane protein changes in erythrocytes predict ribavirin‐induced anemia

P. Portincasa, I. Grattagliano, S. Russmann, 2005, Clinical pharmacology and therapeutics.

The cholecystokinin‐1 receptor antagonist devazepide increases cholesterol cholelithogenesis in mice

P. Portincasa, Helen H. Wang, D. Q. Wang, 2016, European journal of clinical investigation.

Effects of Ursodeoxycholic Acid Therapy on In Vitro Gallbladder Contractility in Patients with Cholesterol Gallstones

F. Hoebers, H. Doornewaard, P. Portincasa, 2004, Digestive Diseases and Sciences.

Effects of simvastatin and cholestyramine on bile lipid composition and gall bladder motility in patients with hypercholesterolaemia.

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 1995, Gut.

Gallbladder emptying in vivo, bile composition, and nucleation of cholesterol crystals in patients with cholesterol gallstones.

P. Portincasa, K. V. van Erpecum, W. Renooij, 1995, Gastroenterology.

Effects of bile salt and phospholipid hydrophobicity on lithogenicity of human gallbladder bile

P. Portincasa, W. Renooij, K. Erpecum, 1994, European journal of clinical investigation.

Special article Water handling and aquaporins in bile formation: recent advances and research trends

G. Calamita, P. Portincasa, A. Moschetta, 2003 .

Current pharmacological treatment of nonalcoholic fatty liver.

P. Portincasa, I. Grattagliano, G. Palasciano, 2006, Current medicinal chemistry.

Medicinal treatments of cholesterol gallstones: old, current and new perspectives.

P. Portincasa, A. Moschetta, Helen H. Wang, 2009, Current medicinal chemistry.

Sourdough Fermented Breads are More Digestible than Those Started with Baker’s Yeast Alone: An In Vivo Challenge Dissecting Distinct Gastrointestinal Responses

P. Portincasa, M. Montemurro, M. Lorusso, 2019, Nutrients.

Sensitive response to ingestion of lipids in dyspepsia

P. Portincasa, M. Montagna, F. Caponio, 2018 .

Environmental health, COVID-19, and the syndemic: internal medicine facing the challenge

P. Portincasa, H. Moshammer, P. Lauriola, 2022, Internal and Emergency Medicine.

The "hemolysis model" for the study of cyto-toxicity and cyto-protection by bile salts and phospholipids.

M. Vacca, M. Krawczyk, P. Portincasa, 2006, Advances in experimental medicine and biology.

Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease.

P. Portincasa, L. Bonfrate, R. Ribeiro, 2022, European journal of internal medicine.

Overcoming Ductal Block: Emergency ERCP and Sphincterotomy Plus Common Bile Duct Stenting Improves Therapeutic Outcomes in Severe Gallstone Pancreatitis

P. Portincasa, P. Tso, Min Liu, 2021, Digestive Diseases and Sciences.

Recent Advances in the Digestive, Metabolic and Therapeutic Effects of Farnesoid X Receptor and Fibroblast Growth Factor 19: From Cholesterol to Bile Acid Signaling

P. Portincasa, G. Garruti, F. Stellaard, 2022, Nutrients.

Taurodeoxycholate-induced intestinal injury is modulated by oxidative stress-dependent pre-conditioning like mechanisms.

P. Portincasa, A. Moschetta, I. Grattagliano, 2008, Toxicology letters.

Lipid transport into bile and role in bile formation.

G. Calamita, P. Portincasa, M. Svelto, 2005 .

Gallstones

P. Portincasa, David Q.‐H. Wang, 2022, Yamada's Textbook of Gastroenterology.

The Dyspeptic Syndrome in Migraine: Morphofunctional Evaluation on 53 Patients

P. Portincasa, O. Albano, F. Doronzo, 1996, Headache.

Non-alcoholic fatty liver disease in the metabolic syndrome.

P. Portincasa, A. Moschetta, I. Grattagliano, 2007, Current pharmaceutical design.

Cholesterol crystallisation in bile

P. Portincasa, K. V. van Erpecum, G. P. vanBerge-Henegouwen, 1997, Gut.

Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect.

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 1995, Scandinavian journal of gastroenterology. Supplement.

Liver function as assessed by breath tests in patients with hepatocellular carcinoma.

P. Portincasa, I. Grattagliano, G. Palasciano, 2009, The Journal of surgical research.

Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer.

P. Portincasa, F. Pellegrini, G. Piccinni, 2003, World journal of gastroenterology.

P. Portincasa, P. Tso, Helen H. Wang, 2018, Liver research.

Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts.

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2000, Journal of lipid research.

The Role of Environmental Pollution in Endocrine Diseases

P. Portincasa, A. Ciaula, 2020, Endocrinology.

An Innovative Synbiotic Formulation Decreases Free Serum Indoxyl Sulfate, Small Intestine Permeability and Ameliorates Gastrointestinal Symptoms in a Randomized Pilot Trial in Stage IIIb-IV CKD Patients

L. Gesualdo, P. Portincasa, Simone Corciulo, 2021, Toxins.

Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis.

G. Calamita, P. Portincasa, M. Svelto, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall‐bladder epithelium

G. Calamita, P. Portincasa, M. Paulmichl, 2005, Biology of the cell.

Micellar lipid composition profoundly affects LXR‐dependent cholesterol transport across CaCo2 cells

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2009, FEBS letters.

Effects of Aramchol on in vitro bile cholesterol crystallization and bile acid detergency

P. Portincasa, M. Petruzzelli, N. Venneman, 2008 .

Quantitation of cholesterol crystallization from supersaturated model bile.

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2002, Journal of lipid research.

Impact of adipokines and myokines on fat browning

G. Frühbeck, P. Portincasa, V. Catalán, 2020, Journal of Physiology and Biochemistry.

Distinct Effects of two Almond Cultivars on Agreeability and Gastrointestinal Motility in Healthy Subjects: more than mere Nutraceuticals.

P. Portincasa, M. Lorusso, M. Montagna, 2018, Journal of gastrointestinal and liver diseases : JGLD.

The effect of silymarin on plasma levels of malon-dialdehyde in patients receiving long-term treatment with psychotropic drugs

P. Portincasa, G. Palasciano, G. Vendemiale, 1994 .

Evidence of lipid peroxidation in patients taking neuroleptic drugs

P. Portincasa, G. Palasciano, G. Vendemiale, 1994 .

New insights into the molecular mechanism of intestinal fatty acid absorption

P. Portincasa, David Q.‐H. Wang, Min Liu, 2013, European journal of clinical investigation.

Primary sclerosing cholangitis: updates in diagnosis and therapy.

M. Vacca, P. Portincasa, A. Moschetta, 2005, World journal of gastroenterology.

COVID‐19, internists and resilience: the north‐south Italy outbreak

P. Portincasa, V. Palmieri, A. Di Ciaula, 2020, European journal of clinical investigation.

COVID‐19: Focus on the lungs but do not forget the gastrointestinal tract

Maciej K. Janik, F. Lammert, M. Krawczyk, 2020, European journal of clinical investigation.

Novel insights in health-promoting properties of sweet cherries

M. L. Clodoveo, P. Portincasa, F. Corbo, 2020, Journal of functional foods.

Cholesterol cholelithiasis: part of a systemic metabolic disease, prone to primary prevention

P. Portincasa, A. Di Ciaula, D. Q. Wang, 2018, Expert review of gastroenterology & hepatology.

Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study

G. Celano, P. Portincasa, M. Gobbetti, 2019, Nutrients.

Aquaporins as Targets of Dietary Bioactive Phytocompounds

G. Calamita, P. Portincasa, G. Tamma, 2018, Front. Mol. Biosci..

The Biliary System: Second Edition

B. Neuschwander‐Tetri, P. Portincasa, D. Q. Wang, 2016 .

Pathophysiology of cholesterol gallstone disease

P. Portincasa, A. Moschetta, A. Ciaula, 2008 .

Nucleation behaviour of various cholesterol (xol) crystals in bile from gallstone patients

P. Portincasa, W. Renooij, M. Gadellaa, 1995 .

Effects of Biliary Phospholipids on Cholesterol Crystallization and Growth in Gallstone Formation

P. Portincasa, Min Liu, D. Q. Wang, 2023, Advances in Therapy.

Lith genes and genetic analysis of cholesterol gallstone formation.

P. Portincasa, N. Afdhal, Helen H. Wang, 2010, Gastroenterology clinics of North America.

Pathways of cholesterol crystallization in model bile and native bile.

G. Calamita, P. Portincasa, A. Moschetta, 2003, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Cholesterol crystallization in human gallbladder bile: Relation to gallstone number, bile composition, and apolipoprotein E4 isoform

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 1998, Hepatology.

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome.

A. Gasbarrini, P. Portincasa, N. Caporaso, 2016, Journal of gastrointestinal and liver diseases : JGLD.

Prolonged consumption of moderate doses of alcohol and in vitro gastro‐duodenal and ileal contractility in the rat

P. Portincasa, A. Ciaula, G. Palasciano, 1995, European journal of clinical investigation.

Increased gall bladder volume in primary sclerosing cholangitis.

P. Portincasa, K. V. van Erpecum, G. P. vanBerge-Henegouwen, 1996, Gut.

Efficacy of bio-optimized extracts of turmeric and essential fennel oil on the quality of life in patients with irritable bowel syndrome

P. Portincasa, A. Albert, A. Di Ciaula, 2018, Annals of gastroenterology.

A Mitochondrial Approach to Cardiovascular Risk and Disease.

P. Portincasa, Luciana L. Ferreira, P. Oliveira, 2019, Current protein & peptide science.

Transverse leukonychia in severe hypocalcemia.

C. Foti, G. Vena, P. Portincasa, 2004, European journal of dermatology : EJD.

COVID-19: Specific and Non-Specific Clinical Manifestations and Symptoms: The Current State of Knowledge

H. Karakuła-Juchnowicz, P. Portincasa, R. Maciejewski, 2020, Journal of clinical medicine.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

H. Zischka, A. Dobrzyń, P. Portincasa, 2018, International review of cell and molecular biology.

Bovine Pericardium Patch Wrapping Intestinal Anastomosis Improves Healing Process and Prevents Leakage in a Pig Model

P. Portincasa, F. Staffieri, A. Crovace, 2014, PloS one.

Contractility In Vitro and Mitochondrial Response in Small and Large Rabbit Bowel after Anastomosis

P. Portincasa, G. Piccinni, M. Testini, 2002, World Journal of Surgery.

Fat, epigenome and pancreatic diseases. Interplay and common pathways from a toxic and obesogenic environment.

P. Portincasa, A. Di Ciaula, 2014, European journal of internal medicine.

The food-gut human axis: the effects of diet on gut microbiota and metabolome.

Marco Gobbetti, Piero Portincasa, P. Portincasa, 2019, Current medicinal chemistry.

Bile Acid Physiology.

P. Portincasa, G. Garruti, L. Bonfrate, 2017, Annals of hepatology.

Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial.

I. de Sio, A. Floreani, I. Sporea, 2012, Free radical biology & medicine.

Water channel proteins in bile formation and flow in health and disease: when immiscible becomes miscible.

G. Calamita, P. Portincasa, 2012, Molecular aspects of medicine.

The Biliary System

B. Neuschwander‐Tetri, P. Portincasa, D. Q. Wang, 2012 .

Hepatic consequences of COVID-19 infection. Lapping or biting?

F. Lammert, M. Krawczyk, P. Portincasa, 2020, European Journal of Internal Medicine.

Cholesterol cholelithiasis in pregnant women: pathogenesis, prevention and treatment.

P. Portincasa, C. Paik, Min Liu, 2014, Annals of hepatology.

Liver Glycerol Permeability and Aquaporin-9 Are Dysregulated in a Murine Model of Non-Alcoholic Fatty Liver Disease

G. Calamita, G. Frühbeck, P. Portincasa, 2013, PloS one.

Effects of dietary education, followed by a tailored fructose-restricted diet in adults with fructose malabsorption

F. Lammert, M. Krawczyk, P. Portincasa, 2015, European journal of gastroenterology & hepatology.

Gender-dependent impact of COVID-19 lockdown on metabolic and psychological aspects

P. Portincasa, G. Vilahur, L. Bonfrate, 2023, Internal and Emergency Medicine.

How best to manage chronic cholestasis.

A. Floreani, P. Portincasa, I. Grattagliano, 2018, The Journal of family practice.

Adefovir Dipivoxyl for the Treatment of Delta-Related Liver Cirrhosis

P. Portincasa, I. Grattagliano, G. Palasciano, 2006, The Annals of Pharmacotherapy.

The Controversial Role of Human Gut Lachnospiraceae

G. Celano, P. Portincasa, M. Gobbetti, 2020, Microorganisms.

Models of non-Alcoholic Fatty Liver Disease and Potential Translational Value: the Effects of 3,5-L-diiodothyronine.

P. Portincasa, L. Vergani, L. Canesi, 2017, Annals of hepatology.

Concordance of genetic and breath tests for lactose intolerance in a tertiary referral centre.

F. Lammert, M. Krawczyk, T. Sauerbruch, 2008, Journal of gastrointestinal and liver diseases : JGLD.

Ribavirin-induced anemia: mechanisms, risk factors and related targets for future research.

P. Portincasa, I. Grattagliano, S. Russmann, 2006, Current medicinal chemistry.

EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones.

F. Lammert, P. Portincasa, G. Ercolani, 2016, Journal of hepatology.

Clinical Practice Guidelines on the prevention , diagnosis and treatment of gallstones q European Association for the Study of the Liver ( EASL ) ⇑

P. Portincasa, G. Ercolani, K. Gurusamy, 2016 .

Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis

M. Sperandio, P. Portincasa, M. De Angelis, 2022, International journal of molecular sciences.

Dissecting the Genetic Heterogeneity of Gallbladder Stone Formation

F. Lammert, M. Krawczyk, P. Portincasa, 2011, Seminars in liver disease.

New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation.

Piero Portincasa, P. Portincasa, D. Clegg, 2009, Biochimica et biophysica acta.

MicroRNA in colorectal cancer: new perspectives for diagnosis, prognosis and treatment.

P. Portincasa, M. Rotelli, D. Altomare, 2013, Journal of gastrointestinal and liver diseases : JGLD.

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

Laurent F. Thomas, G. Abecasis, A. Auton, 2021, Nature Genetics.

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

P. Portincasa, I. Korona-Głowniak, J. Baj, 2020, Cells.

Mouse models of gallstone disease

P. Portincasa, P. Tso, Min Liu, 2017, Current opinion in gastroenterology.

Diagnostic value of calprotectin in irritable bowel syndrome and in inflammatory bowel disease.

P. Portincasa, D. Dumitrascu, C. Grad, 2012, Romanian journal of internal medicine = Revue roumaine de medecine interne.

Fecal microRNA profile in patients with colorectal carcinoma before and after curative surgery

P. Portincasa, M. Rotelli, D. Altomare, 2015, International Journal of Colorectal Disease.

Microbiota in health and irritable bowel syndrome: current knowledge, perspectives and therapeutic options

P. Portincasa, R. Cuomo, J. Tack, 2013, Scandinavian journal of gastroenterology.

Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis.

P. Portincasa, A. Moschetta, I. Grattagliano, 2008, The Journal of nutritional biochemistry.

Effects of diets on adipose tissue.

G. Frühbeck, P. Portincasa, Amaia Rodríguez, 2019, Current medicinal chemistry.

Gut Microbiota between Environment and Genetic Background in Familial Mediterranean Fever (FMF)

P. Portincasa, L. Bonfrate, A. Stella, 2020, Genes.

Current Views on Genetics and Epigenetics of Cholesterol Gallstone Disease

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2013, Cholesterol.

Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study

S. Passaretti, E. Buscarini, M. Bellini, 2017, BMC Gastroenterology.

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Casey S. Greene, Marco Carbone, Andrew Fraser, 2015, Nature Communications.

Intestinal Barrier and Permeability in Health, Obesity and NAFLD

M. D’Amato, P. Portincasa, F. Calabrese, 2021, Biomedicines.

Liver Steatosis, Gut-Liver Axis, Microbiome and Environmental Factors. A Never-Ending Bidirectional Cross-Talk

G. Celano, P. Portincasa, G. Garruti, 2020, Journal of clinical medicine.

The environment as a determinant of successful aging or frailty

P. Portincasa, A. Di Ciaula, 2020, Mechanisms of Ageing and Development.

Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease

G. Calamita, P. Portincasa, M. Svelto, 2007, European journal of clinical investigation.

FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes

G. Frühbeck, P. Portincasa, V. Catalán, 2021, Cellular & Molecular Immunology.

Immunological Aspects of the Tumor Microenvironment and Epithelial-Mesenchymal Transition in Gastric Carcinogenesis

P. Portincasa, J. Baj, Alicja Forma, 2020, International journal of molecular sciences.

X chromosome contribution to the genetic architecture of primary biliary cholangitis.

Aaron M. King, Elizabeth G. Atkinson, K. Siminovitch, 2021, Gastroenterology.

Gastrointestinal symptoms and motility disorders in patients with systemic scleroderma

P. Portincasa, M. Covelli, G. Lapadula, 2008, BMC gastroenterology.

Multiplying effects of COVID‐19 lockdown on metabolic risk and fatty liver

P. Portincasa, G. Garruti, M. Faienza, 2021, European journal of clinical investigation.

Ultrasonographic study of postcibal gastro-esophageal reflux and gastric emptying in infants with recurrent respiratory disease.

P. Portincasa, G. Palasciano, A. Di Ciaula, 2005, World journal of gastroenterology.

Unexpected discovery of massive liver echinococcosis. A clinical, morphological, and functional diagnosis.

F. Giuliante, P. Portincasa, G. Palasciano, 2013, Annals of hepatology.

The rationale for targeting TGF‐β in chronic liver diseases

S. Dooley, P. Winter, G. Giannelli, 2016, European journal of clinical investigation.

Obesity and the risk and prognosis of gallstone disease and pancreatitis.

P. Portincasa, G. Garruti, L. Bonfrate, 2014, Best practice & research. Clinical gastroenterology.

Coordinate Regulation of Gallbladder Motor Function in the Gut-liver Axis

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2022 .

Recent advances in understanding and managing cholesterol gallstones

P. Portincasa, A. Di Ciaula, 2018, F1000Research.

An update on the pathogenesis and treatment of cholesterol gallstones.

P. Portincasa, K. V. van Erpecum, G. Palasciano, 1997, Scandinavian journal of gastroenterology. Supplement.

Motilin induces gall bladder emptying and antral contractions in the fasted state in humans

P. Portincasa, I. Depoortere, L. Akkermans, 1998, Gut.

Changes of gallbladder and gastric dynamics in patients with acute hepatitis A

P. Portincasa, M. Milella, A. Moschetta, 2001, European journal of clinical investigation.

The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study

P. Portincasa, A. Moschetta, A. Ciaula, 2000, American Journal of Gastroenterology.

Intestinal permeability in patients with chronic liver diseases: Its relationship with the aetiology and the entity of liver damage.

P. Portincasa, A. Federico, C. Loguercio, 2010, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Total thyroidectomy is improved by loupe magnification

P. Portincasa, G. Piccinni, M. Nacchiero, 2004, Microsurgery.

The Apposition of a Resorbable Pericardial Bovine Patch (Tutomesh®) on Intestinal Anastomoses Improves Functional Mucosal Recovery in Pig Ileum and Colon Assessed by Ussing Chamber Electrophysiological Studies

P. Portincasa, F. Staffieri, A. Crovace, 2011 .

Contractility in vitro and mitochondrial response in small and large anastomized rabbit bowel.

P. Portincasa, G. Piccinni, M. Testini, 2000 .

Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling.

P. Portincasa, P. Oliveira, P. Pinton, 2013, The international journal of biochemistry & cell biology.

Absence of apolipoprotein E4 genotype, good gallbladder motility and presence of solitary stones delay rather than prevent gallstone recurrence after extracorporeal shock wave lithotripsy.

P. Portincasa, K. V. van Erpecum, N. Venneman, 2000, Journal of hepatology.

Critical Care Aspects of Gallstone Disease

P. Portincasa, G. Garruti, D. Q. Wang, 2019, Journal of critical care medicine.

Does Mediastinal Extension of the Goiter Increase Morbidity of Total Thyroidectomy? A Multicenter Study of 19,662 Patients

P. Portincasa, C. Lombardi, R. Bellantone, 2011, Annals of Surgical Oncology.

Bile Acids and Cancer: Direct and Environmental-Dependent Effects.

G. Calamita, P. Portincasa, V. Palmieri, 2017, Annals of hepatology.

Helicobacter pylori Infection and Extragastric Diseases—A Focus on the Central Nervous System

P. Portincasa, G. Garruti, Izabela Morawska, 2021, Cells.

A novel therapeutic effect of statins on nephrogenic diabetes insipidus

P. Portincasa, M. Svelto, L. Bonfrate, 2015, Journal of cellular and molecular medicine.

Irritable bowel syndrome and diet

P. Portincasa, A. Lembo, S. Ballou, 2017, Gastroenterology report.

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

G. Calamita, B. Ogunjimi, P. Portincasa, 2020, Annals of the Rheumatic Diseases.

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

Fabio Macciardi, Angelo Andriulli, Nicola Caporaso, 2010, Nature Genetics.

Role of Sumac (Rhus coriaria L.) in the management of metabolic syndrome and related disorders: Focus on NAFLD-atherosclerosis interplay

P. Portincasa, N. Khalil, M. Calasso, 2021, Journal of Functional Foods.

Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation

G. Frühbeck, P. Portincasa, V. Catalán, 2017, Scientific Reports.

PNPLA3-Associated Steatohepatitis: Toward a Gene-Based Classification of Fatty Liver Disease

F. Lammert, M. Krawczyk, P. Portincasa, 2013, Seminars in Liver Disease.

PNPLA 3-Associated Steatohepatitis : Toward a Gene-Based Classi fi cation of Fatty Liver Disease

F. Lammert, M. Krawczyk, P. Portincasa, 2013 .

Loss-of-function of the voltage-gated sodium channel NaV1.5 (channelopathies) in patients with irritable bowel syndrome.

M. Gazouli, M. Camilleri, D. Tester, 2014, Gastroenterology.

Predictive value of the Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the outcome of diverticular disease of the colon: An international study

S. Bonovas, K. Søreide, G. Rotondano, 2016, United European gastroenterology journal.

Nonalcoholic steatohepatitis: recent advances from experimental models to clinical management.

P. Portincasa, I. Grattagliano, G. Palasciano, 2005, Clinical biochemistry.

Bile Acids and Cancer: Direct and Environmental-Dependent Effects.

G. Calamita, P. Portincasa, V. Palmieri, 2017, Annals of hepatology.

Sequential therapy for first-line Helicobacter pylori eradication: 10- or 14-day regimen?

A. Zullo, A. Amato, P. Portincasa, 2019, Journal of gastrointestinal and liver diseases : JGLD.

Low membrane protein sulfhydrils but not G6PD deficiency predict ribavirin‐induced hemolysis in hepatitis C

P. Portincasa, I. Grattagliano, S. Russmann, 2004, Hepatology.

Mitochondria in Liver Diseases

P. Portincasa, P. Oliveira, I. Grattagliano, 2018 .

The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women

P. Portincasa, G. Furtado, A. Bachi, 2021, European journal of clinical investigation.

Gallbladder motility and functional gastrointestinal disorders.

P. Portincasa, A. Colecchia, D. Festi, 2003, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Steatosis in the liver.

B. Neuschwander‐Tetri, P. Portincasa, David Q.‐H. Wang, 2013, Comprehensive Physiology.

Bismuth-based quadruple therapy following H. pylori eradication failures: a multicenter study in clinical practice.

A. Zullo, P. Portincasa, R. Sacco, 2017, Journal of gastrointestinal and liver diseases : JGLD.

Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.

C. Hassan, A. Zullo, P. Portincasa, 2013, Clinics and research in hepatology and gastroenterology.

Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome

G. Frühbeck, P. Portincasa, V. Catalán, 2017, Scientific Reports.

Management of gallstones and its related complications

P. Portincasa, G. Garruti, A. Ciaula, 2016, Expert review of gastroenterology & hepatology.

Obesity phenotypes and their paradoxical association with cardiovascular diseases.

G. Frühbeck, P. Portincasa, F. Montecucco, 2017, European journal of internal medicine.

Impaired gallbladder motility and delayed orocecal transit contribute to pigment gallstone and biliary sludge formation in beta-thalassemia major adults.

M. Vacca, P. Portincasa, A. Moschetta, 2004, World journal of gastroenterology.

Aging and nutrition. Paving the way to better health

P. Portincasa, G. Garruti, I. Grattagliano, 2020, Romanian journal of internal medicine = Revue roumaine de medecine interne.

Long-Term Functional Assessment of Antegrade Colonic Enema for Combined Incontinence and Constipation Using a Modified Marsh and Kiff Technique

P. Portincasa, G. Rubini, V. Memeo, 2007, Diseases of the colon and rectum.

Drug‐induced enterocolitis: Prevention and management in primary care

P. Portincasa, I. Grattagliano, E. Ubaldi, 2018, Journal of digestive diseases.

Reproducibility and validity of the Italian version of the International Physical Activity Questionnaire in obese and diabetic patients

G. Biolo, F. Pigozzi, D. Lucini, 2018, Journal of Endocrinological Investigation.

Present and future therapeutic strategies in non-alcoholic fatty liver disease

G. Calamita, P. Portincasa, 2007, Expert opinion on therapeutic targets.

ff ects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms : A Randomised , Double-Blind , Cross-Over Study

G. Celano, P. Portincasa, M. Gobbetti, 2019 .

Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome

M. Camilleri, A. Franke, M. D’Amato, 2016, Gut.

Relationships between emissions of toxic airborne molecules and type 1 diabetes incidence in children: An ecologic study

P. Portincasa, A. Di Ciaula, 2021, World journal of diabetes.

Role of mitochondria in nonalcoholic fatty liver disease--from origin to propagation.

P. Portincasa, P. Oliveira, I. Grattagliano, 2012, Clinical biochemistry.

Effects of temporary sacral nerve stimulation on gastrointestinal motility and function in patients with chronic refractory slow-transit constipation

P. Portincasa, M. De Fazio, D. Altomare, 2020, Techniques in Coloproctology.

Colchicine, Biologic Agents and More for the Treatment of Familial Mediterranean Fever. The Old, the New, and the Rare.

P. Portincasa, 2016, Current medicinal chemistry.

Defective in vitro contractility of ureteropelvic junction in children with functional and obstructive urine flow impairment.

P. Portincasa, G. Palasciano, A. Di Ciaula, 2006, Journal of pediatric surgery.

Pan-enteric dysmotility, impaired quality of life and alexithymia in a large group of patients meeting ROME II criteria for irritable bowel syndrome.

P. Portincasa, A. Moschetta, G. Palasciano, 2003, World journal of gastroenterology.

Slow-transit constipation

P. Portincasa, A. Ciaula, A. Amoruso, 1999, Diseases of the colon and rectum.

Isolation and functional characterization of rat pancreatic acini.

A. Velardi, P. Portincasa, G. Palasciano, 1990, Bollettino della Societa italiana di biologia sperimentale.

Diet and contaminants: driving the rise to obesity epidemics?

P. Portincasa, A. Di Ciaula, 2019, Current medicinal chemistry.

Fatty Acid Oxidation and Cardiovascular Risk during Menopause: A Mitochondrial Connection?

P. Portincasa, P. Oliveira, L. Bonfrate, 2012, Journal of lipids.

Impact of Endocrine Disorders on Gastrointestinal Diseases

P. Portincasa, A. Ciaula, T. Sommers, 2020, Endocrinology.

Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition.

G. Damonte, G. Calamita, P. Portincasa, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Nonalcoholic Fatty Liver Disease (NAFLD). Mitochondria as Players and Targets of Therapies?

P. Portincasa, S. Passarella, L. Bonfrate, 2021, International journal of molecular sciences.

Mitochondria Matter: Systemic Aspects of Nonalcoholic Fatty Liver Disease (NAFLD) and Diagnostic Assessment of Liver Function by Stable Isotope Dynamic Breath Tests

G. Calamita, P. Portincasa, G. Baffy, 2021, International journal of molecular sciences.

Review article: in vitro studies of gall‐bladder smooth muscle function. Relevance in cholesterol gallstone disease

P. Portincasa, A. Moschetta, N. Venneman, 2000, Alimentary pharmacology & therapeutics.

Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome

P. Portincasa, Helen H Wang, Min Liu, 2020, Pediatric gastroenterology, hepatology & nutrition.

High-fat diet alters the oligosaccharide chains of colon mucins in mice

G. Calamita, P. Portincasa, M. Mastrodonato, 2014, Histochemistry and Cell Biology.

COVID‐19 and non‐alcoholic fatty liver disease: Two intersecting pandemics

Marcin Krawczyk, Piero Portincasa, F. Lammert, 2020, European journal of clinical investigation.

Diagnostic delay in adult coeliac disease: An Italian multicentre study.

A. Gasbarrini, A. Vanoli, G. Corazza, 2022, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Standards for diagnosis gastrointestinal motility disorders. Section: ultrasonography position statement from the Gruppo Italiano di Studio Motilità Apparato Digerente (GISMAD)

P. Portincasa, A. Ciaula, M. Muraca, 2000 .

Long-term management of chronic heart failure patients in internal medicine

P. Portincasa, V. Palmieri, E. Settimo, 2019, Internal and Emergency Medicine.

Small intestinal bacterial overgrowth produces symptoms in irritable bowel syndrome which are improved by rifaximin. A pilot study.

P. Portincasa, M. Diculescu, D. Dumitrascu, 2013, Romanian journal of internal medicine = Revue roumaine de medecine interne.

Small Intestinal Bacterial Overgrowth is Associated to Symptoms in Irritable Bowel Syndrome. Evidence from a Multicentre Study in Romania. Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome

I. Hațieganu, P. Portincasa, M. Diculescu, 2014 .

Small intestinal bacterial overgrowth is associated to symptoms in irritable bowel syndrome. Evidence from a multicentre study in Romania.

P. Portincasa, M. Diculescu, D. Dumitrascu, 2014, Romanian journal of internal medicine = Revue roumaine de medecine interne.

Bacterial flora, gas and antibiotics

P. Portincasa, V. Ruggiero, E. Scaioli, 2009 .

Constipation after hysterectomy: fact or fiction?

P. Portincasa, D. Altomare, M. Rinaldi, 2000, The European journal of surgery = Acta chirurgica.

Managing nonalcoholic fatty liver disease: recommendations for family physicians.

P. Portincasa, I. Grattagliano, G. Palasciano, 2007, Canadian family physician Medecin de famille canadien.

The Role Of Diet In The Pathogenesis Of Cholesterol Gallstones.

F. Lammert, G. Frühbeck, P. Portincasa, 2019, Current medicinal chemistry.

Biomechanics of cultured hepatic cells during different steatogenic hits.

A. Bartolozzi, M. Vassalli, P. Portincasa, 2019, Journal of the mechanical behavior of biomedical materials.

Childhood obesity, cardiovascular and liver health: a growing epidemic with age

F. Lammert, M. Krawczyk, P. Portincasa, 2020, World Journal of Pediatrics.

Nonalcoholic fatty liver disease.

M. Krawczyk, P. Portincasa, L. Bonfrate, 2010, Best practice & research. Clinical gastroenterology.

The physical presence of gallstone modulates ex vivo cholesterol crystallization pathways of human bile

P. Portincasa, K. V. van Erpecum, A. Di Ciaula, 2018, Gastroenterology report.

OP-GAST180045 32..41

P. Portincasa, A. Ciaula, K. Erpecum, 2019 .

Higher protein intake is associated with improved muscle strength in elite senior athletes.

G. Biolo, F. Pigozzi, D. Lucini, 2017, Nutrition.

Mitochondria in chronic liver disease.

P. Portincasa, P. Oliveira, I. Grattagliano, 2011, Current drug targets.

Post COVID-19 irritable bowel syndrome

M. Zoli, U. Ghoshal, M. Bellini, 2022, Gut.

Pulmonary Artery Filling Defects in COVID-19 Patients Revealed Using CT Pulmonary Angiography: A Predictable Complication?

P. Portincasa, A. Scardapane, G. Angarano, 2021, BioMed research international.

S1839 Effect of Silybin in Patients With Chronic Hepatitis: Preliminary Results of a Multicentre Randomized Controlled Trial vs Placebo

A. Floreani, I. Sporea, S. Milani, 2010 .

Recurrence of COVID-19 after recovery: a case report from Italy

P. Portincasa, F. Centrone, M. Chironna, 2020, Infection.

Protocols for Mitochondria as the Target of Pharmacological Therapy in the Context of Nonalcoholic Fatty Liver Disease (NAFLD).

P. Portincasa, G. Garruti, I. Grattagliano, 2021, Methods in molecular biology.

Effects of cholestyramine on gallbladder and gastric emptying in obese and lean subjects

P. Portincasa, A. Ciaula, G. Palasciano, 1995, European journal of clinical investigation.

Is It Possible to Predict the Clinical Course of Gallstone Disease? Usefulness of Gallbladder Motility Evaluation in a Clinical Setting

P. Portincasa, A. Colecchia, D. Festi, 2006, The American Journal of Gastroenterology.

Gallbladder and gastric motility in obese newborns, pre‐adolescents and adults

P. Portincasa, A. Di Ciaula, D. Q. Wang, 2012, Journal of gastroenterology and hepatology.

Therapy of gallstone disease: What it was, what it is, what it will be.

P. Portincasa, A. Ciaula, L. Bonfrate, 2012, World journal of gastrointestinal pharmacology and therapeutics.

Targets for current pharmacologic therapy in cholesterol gallstone disease.

P. Portincasa, L. Bonfrate, D. Q. Wang, 2010, Gastroenterology clinics of North America.

Gallstone disease: Symptoms and diagnosis of gallbladder stones.

P. Portincasa, A. Moschetta, M. Petruzzelli, 2006, Best practice & research. Clinical gastroenterology.

Faculty Opinions recommendation of Systematic review and meta-analysis of randomized clinical trials comparing single-incision versus conventional laparoscopic cholecystectomy.

P. Portincasa, L. Bonfrate, 2013 .

Noncommunicable diseases, climate change and iniquities: What COVID‐19 has taught us about syndemic

M. Krawczyk, P. Portincasa, A. Geier, 2021, European journal of clinical investigation.

The morphology and application of stem cells in digestive system surgery.

P. Portincasa, C. Grochowski, J. Baj, 2020, Folia morphologica.

Effect of tauroursodeoxycholic acid on serum liver enzymes and dyspeptic symptoms in patients with chronic active hepatitis

P. Portincasa, C. Sabbà, G. Palasciano, 1993 .

Recent Advances in the Critical Role of the Sterol Efflux Transporters ABCG5/G8 in Health and Disease.

P. Portincasa, Helen H Wang, Min Liu, 2020, Advances in experimental medicine and biology.

Cholesterol and Lipoprotein Metabolism and Atherosclerosis: Recent Advances In reverse Cholesterol Transport.

P. Portincasa, G. Garruti, Helen H Wang, 2017, Annals of hepatology.

Management of liver cirrhosis between primary care and specialists.

Ignazio Grattagliano, Piero Portincasa, P. Portincasa, 2011, World journal of gastroenterology.

Assessing gastrointestinal symptoms and perception, quality of life, motility, and autonomic neuropathy in clinical studies.

P. Portincasa, D. Dumitrascu, O. Todarello, 2009, Journal of gastrointestinal and liver diseases : JGLD.

Cholecystectomy and risk of metabolic syndrome.

P. Portincasa, G. Garruti, A. Di Ciaula, 2018, European journal of internal medicine.

A Pleiotropic Role for the Orphan Nuclear Receptor Small Heterodimer Partner in Lipid Homeostasis and Metabolic Pathways

P. Portincasa, G. Garruti, L. Bonfrate, 2012, Journal of lipids.

Covid-19 and ex-smokers: an underestimated prognostic factor?

P. Portincasa, S. Dragonieri, P. Carratù, 2020, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.

Contribution of the microbiome for better phenotyping of people living with obesity

P. Portincasa, G. Garruti, L. Bonfrate, 2023, Reviews in Endocrine and Metabolic Disorders.

From lipid secretion to cholesterol crystallization in bile. Relevance in cholesterol gallstone disease.

P. Portincasa, A. Moschetta, G. Palasciano, 2002, Annals of hepatology.

Systemic oxidative alterations are associated with visceral adiposity and liver steatosis in patients with metabolic syndrome.

P. Portincasa, I. Grattagliano, G. Palasciano, 2006, The Journal of nutrition.

Regulation of Cholesterol Metabolism by Bioactive Components of Soy Proteins: Novel Translational Evidence

P. Portincasa, M. De Angelis, A. Di Ciaula, 2020, International journal of molecular sciences.

Transintestinal cholesterol excretion: A secondary, nonbiliary pathway contributing to reverse cholesterol transport

P. Portincasa, P. Tso, D. Q. Wang, 2017, Hepatology.

The Vibrio cholerae Cytolysin Promotes Chloride Secretion from Intact Human Intestinal Mucosa

P. Portincasa, R. Fiorotto, M. de Bernard, 2009, PloS one.

Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples.

P. Portincasa, A. De Girolamo, A. Visconti, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Basolateral Ca2+‐dependent K+‐channels play a key role in Cl—secretion induced by taurodeoxycholate from colon mucosa

G. Calamita, P. Portincasa, A. Moschetta, 2003, Biology of the cell.

Analysis of the common vasoactive intestinal peptide receptor 1 polymorphism in gallstone patients.

F. Lammert, M. Krawczyk, P. Portincasa, 2010, Journal of gastrointestinal and liver diseases : JGLD.

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia.

P. Mazzanti, C. Mussi, D. Cucinotta, 2020, Journal of the American Medical Directors Association.

Adipocyte-hepatocyte crosstalk in cellular models of obesity: Role of soluble factors.

A. Diaspro, P. Portincasa, L. Vergani, 2023, Life sciences.

Low membrane protein sulfhydrils but not glucose‐6‐phosphate dehydrogenase deficiency predict ribavirin‐induced hemolysis

P. Portincasa, I. Grattagliano, S. Russmann, 2004 .

Adiponectin involved in portal flow hepatic extraction of 13C-metacethin in obesity and non-alcoholic fatty liver.

P. Portincasa, F. Montecucco, F. Carbone, 2021, European journal of internal medicine.

(13C)-Methacetin breath test provides evidence of subclinical liver dysfunction linked to fat storage but not lifestyle

P. Portincasa, I. Grattagliano, V. Palmieri, 2020, JHEP reports : innovation in hepatology.

Exploring Liver Mitochondrial Function by 13C-Stable Isotope Breath Tests: Implications in Clinical Biochemistry.

P. Portincasa, I. Grattagliano, E. Molina-Molina, 2021, Methods in molecular biology.

The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression

K. Cortese, P. Portincasa, L. Vergani, 2017, Front. Nutr..

Modulation of Aquaporins by dietary patterns and plant bioactive compounds.

G. Calamita, P. Portincasa, G. Tamma, 2017, Current medicinal chemistry.

Phytocompounds modulating Aquaporins: Clinical benefits are anticipated.

G. Calamita, P. Portincasa, 2019, Food chemistry.

An innovative methodology for the automated morphometric and quantitative estimation of liver steatosis.

D Cascella, G. Calamita, P. Portincasa, 2009, Histology and histopathology.

Modulation of hepatic redox status and mitochondrial metabolism by exercise: therapeutic strategy for liver diseases.

A. Ascensão, P. Portincasa, P. Oliveira, 2013, Mitochondrion.

Exercising the hepatobiliary‐gut axis. The impact of physical activity performance

M. Krawczyk, P. Portincasa, O. de Bari, 2018, European journal of clinical investigation.

Intestinal mucosal damage caused by non-steroidal anti-inflammatory drugs: role of bile salts.

M. Vacca, P. Portincasa, A. Moschetta, 2007, Clinical biochemistry.

Management of chronic liver disease by general practitioners in southern Italy: unmet educational needs.

P. Portincasa, I. Grattagliano, C. Loguercio, 2013, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Exploring liver mitochondrial function by ¹³C-stable isotope breath tests: implications in clinical biochemistry.

P. Portincasa, M. Lorusso, I. Grattagliano, 2015, Methods in molecular biology.

13C‐breath tests for clinical investigation of liver mitochondrial function

P. Portincasa, I. Grattagliano, G. Palasciano, 2010, European journal of clinical investigation.

Biliary pronucleating proteins and apolipoprotein E in cholesterol and pigment stone patients.

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 2003, Journal of hepatology.

Increased risk of cholesterol gallstone formation in subjects with apolipoprotein E4 genotype: Its relation to bile composition and crystalization

P. Portincasa, A. Groen, E. Eckhardt, 1998 .

Reduced COVID-19 mortality linked with early antibodies against SARS-CoV-2, irrespective of age

P. Trerotoli, P. Portincasa, M. Montagna, 2022, European Journal of Internal Medicine.

Preventing a Mass Disease: The Case of Gallstones Disease: Role and Competence for Family Physicians

P. Portincasa, I. Grattagliano, A. Di Ciaula, 2016, Korean journal of family medicine.

Risk factors of morbidity in thyroid surgery: analysis of the last 5 years of experience in a general surgery unit.

P. Portincasa, G. Piccinni, M. Nacchiero, 2004, International surgery.

Simvastatin increases AQP2 urinary excretion in hypercholesterolemic patients: A pleiotropic effect of interest for patients with impaired AQP2 trafficking

P. Portincasa, M. Svelto, F. Addabbo, 2016, Clinical pharmacology and therapeutics.

Drugs affecting biliary lipid secretion and gallbladder motility: their potential role in gallstone treatment and prevention.

P. Portincasa, K. V. van Erpecum, N. Venneman, 2005, Current drug targets. Immune, endocrine and metabolic disorders.

Severe impairment of postprandial cholecystokinin release and gall‐bladder emptying and high risk of gallstone formation in acromegalic patients during Sandostatin LAR

J. Rehfeld, P. Portincasa, A. Moschetta, 2001, Alimentary pharmacology & therapeutics.

Enhancement of gallbladder emptying in gallstone patients after oral cholestyramine.

P. Portincasa, G. Palasciano, V. Palmieri, 1994, The American journal of gastroenterology.

Doing better with functional gastrointestinal disorders? Profiling gut microbiota and circulating antibodies to CdtB and vinculin

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2021, European journal of clinical investigation.

The assessment of the nutritional status predicts the long term risk of major events in older individuals

P. Portincasa, I. Grattagliano, T. Mastronuzzi, 2017 .

Assessing the nutritional status of older individuals in family practice: Evaluation and implications for management.

P. Portincasa, I. Grattagliano, T. Mastronuzzi, 2015, Clinical nutrition.

Portal Hypertension in Nonalcoholic Fatty Liver Disease: Challenges and Paradigms

P. Portincasa, Emilie K. Mitten, G. Baffy, 2023, Journal of clinical and translational hepatology.

Esomeprazole-Induced Central Fever with Severe Myalgia

P. Portincasa, I. Grattagliano, G. Palasciano, 2005, The Annals of pharmacotherapy.

Ramadan intermittent fasting reduces visceral fat and improves gastrointestinal motility

P. Portincasa, G. Garruti, L. Bonfrate, 2023, European journal of clinical investigation.

Faculty Opinions recommendation of Cost-effectiveness of emergency versus delayed laparoscopic cholecystectomy for acute gallbladder pathology.

P. Portincasa, 2018, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

Correction to: NAFLD, MAFLD, and beyond: one or several acronyms for better comprehension and patient care

P. Portincasa, 2023, Internal and Emergency Medicine.

Chronic alcoholics retain dyspeptic symptoms, pan‐enteric dysmotility, and autonomic neuropathy before and after abstinence

P. Portincasa, I. Grattagliano, A. Di Ciaula, 2016, Journal of digestive diseases.

NAFLD, MAFLD, and beyond: one or several acronyms for better comprehension and patient care

P. Portincasa, 2023, Internal and Emergency Medicine.

The Impact of Za’atar Antioxidant Compounds on the Gut Microbiota and Gastrointestinal Disorders: Insights for Future Clinical Applications

P. Portincasa, M. De Angelis, M. Calasso, 2023, Antioxidants.

Physical exercise antagonizes clinical and anatomical features characterizing Lieber-DeCarli diet-induced obesity and related metabolic disorders.

A. Ascensão, P. Portincasa, J. Magalhães, 2015, Clinical nutrition.

Dynamic carbon 13 breath tests for the study of liver function and gastric emptying

P. Portincasa, I. Grattagliano, G. Palasciano, 2014, Gastroenterology report.

Re-wiring the circuit: mitochondria as a pharmacological target in liver disease.

P. Portincasa, P. Oliveira, I. Grattagliano, 2011, Current medicinal chemistry.

Impaired gallbladder and gastric motility and pathological gastro‐oesophageal reflux in gallstone patients

A. Velardi, P. Portincasa, G. Palasciano, 1997, European journal of clinical investigation.

CLINICAL INVESTIGATION OF LIVER MITOCHONDRIAL FUNCTION: A ROLE FOR 13 C-STABLE ISOTOPE BREATH TESTS?

P. Portincasa, V. Ruggiero, G. Palasciano, 2010 .

Probiotics in Psychosocial Stress and Anxiety. A Systematic Review.

P. Portincasa, D. Dumitrascu, M. De Angelis, 2020, Journal of gastrointestinal and liver diseases : JGLD.

Impaired intestinal cholecystokinin secretion, a fascinating but overlooked link between coeliac disease and cholesterol gallstone disease

P. Portincasa, Helen H Wang, Min Liu, 2017, European journal of clinical investigation.

Ion transport across the gallbladder epithelium.

G. Calamita, P. Portincasa, M. Paulmichl, 2005, Current Drug Targets - Immune, Endocrine & Metabolic Disorders.

Opposite effects of cholestyramine and loxiglumide on gallbladder dynamics in humans.

P. Portincasa, G. Palasciano, O. Albano, 1992, Gastroenterology.

Ursodeoxycholic acid reduces protein levels and nucleation-promoting activity in human gallbladder bile.

P. Portincasa, K. V. van Erpecum, A. Groen, 1996, Gastroenterology.

Beneficial Effects of Carvacrol on In Vitro Models of Metabolically-Associated Liver Steatosis and Endothelial Dysfunction: A Role for Fatty Acids in Interfering with Carvacrol Binding to Serum Albumin.

P. Portincasa, L. Vergani, G. Lupidi, 2022, Current medicinal chemistry.

Faster Detection of Helicobacter pylori Infection by 13 C-Urea Breath Test. Comparing Short versus Standard Sampling Time.

P. Portincasa, M. Lorusso, T. Rokkas, 2019, Journal of gastrointestinal and liver diseases : JGLD.

T16189C mitochondrial DNA variant is associated with metabolic syndrome in Caucasian subjects.

P. Portincasa, Domenico de Rasmo, A. Signorile, 2011, Nutrition.

Cholesterol and Lipoprotein Metabolism and Atherosclerosis: Recent Advances in Reverse Cholesterol Transport.

P. Portincasa, G. Garruti, Helen H Wang, 2017, Annals of hepatology.

Systematic review with meta‐analysis: Branched‐chain amino acid supplementation in liver disease

F. Vleggaar, P. Portincasa, K. V. van Erpecum, 2022, European journal of clinical investigation.

Metabolic dysfunction-associated gallstone disease: expecting more from critical care manifestations

P. Portincasa, G. Garruti, L. Bonfrate, 2023, Internal and Emergency Medicine.

Gastrointestinal defects in gallstone and cholecystectomized patients

P. Portincasa, D. Dumitrascu, L. Bonfrate, 2019, European journal of clinical investigation.

Effect of Inhibition of Intestinal Cholesterol Absorption on the Prevention of Cholesterol Gallstone Formation.

P. Portincasa, David Q.‐H. Wang, 2017, Medicinal chemistry.

The Relationship between Prebiotic Supplementation and Anthropometric and Biochemical Parameters in Patients with NAFLD—A Systematic Review and Meta-Analysis of Randomized Controlled Trials

P. Portincasa, K. Skonieczna-Żydecka, E. Stachowska, 2020, Nutrients.

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

P.02.12 PREDICTIVE VALUE OF THE “DICA” ENDOSCOPIC CLASSIFICATION ON THE OUTCOME OF DIVERTICULAR DISEASE OF THE COLON: A 1-YEAR ANALYSIS FROM THE INTERNATIONAL, MULTICENTER, PROSPECTIVE STUDY

F. Lammert, M. Franceschi, A. Zullo, 2019, Digestive and Liver Disease.

Genetic and clinical features of familial mediterranean fever (FMF) in a homogeneous cohort of patients from South-Eastern Italy.

P. Portincasa, G. Lopalco, F. Iannone, 2023, European journal of internal medicine.

Stopped-flow Light Scattering Analysis of Red Blood Cell Glycerol Permeability.

G. Calamita, P. Portincasa, M. Rützler, 2020, Bio-protocol.

Predictive Serum Markers of Gallstone Disease: Gazing Into a Crystal Ball.

F. Lammert, M. Krawczyk, P. Portincasa, 2017, Journal of pediatric gastroenterology and nutrition.

The power of science diplomacy, a lesson from the Nobel laureate Peter Agre

G. Calamita, P. Portincasa, 2016, European journal of clinical investigation.

Re-Evaluation of MEFV Gene Variants: Utility of a Gene Specific Threshold in Reducing the Number of Variants of Unknown Significance

M. Accetturo, P. Portincasa, A. M. D’Uggento, 2019, bioRxiv.

Histopathological characteristics of synovitis in Familial Mediterranean Fever (FMF).

P. Portincasa, G. Lopalco, F. Iannone, 2021, Joint bone spine.

Raising the curtain: from the gut lumen to human health and disease—the point of interest for internal medicine

P. Portincasa, R. Ciccocioppo, 2023, Internal and Emergency Medicine.

Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.

P. Portincasa, P. Simoni, E. Vitacolonna, 2005, World journal of gastroenterology.

and 13 C-phenylalanine breath tests in chronic liver disease: Comparison with Child-Pugh score and serum bile acid levels

P. Portincasa, P. Simoni, E. Vitacolonna, 2005 .

Methacetin Breath Test

P. Portincasa, P. Simoni, E. Vitacolonna, 2004 .

Current treatments of primary sclerosing cholangitis.

M. Krawczyk, P. Portincasa, A. Moschetta, 2007, Current medicinal chemistry.

Drug reaction with eosinophilia and systemic symptoms caused by lenalidomide.

C. Foti, P. Portincasa, A. Mazzocca, 2012, European journal of dermatology : EJD.

Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

K. Siminovitch, C. Amos, M. Seldin, 2013, Genes and Immunity.

Efficacy of a new nutraceutical formulation: L-tryptophan, probiotics, charcoal, chamomile, mint, and licorice (COLONIR®) in the improvement of gastrointestinal symptoms in subjects with irritable bowel syndrome.

P. Portincasa, C. Borghi, Emiliano De Vergori, 2023, Minerva gastroenterology.

Linking Metallic Micronutrients and Toxic Xenobiotics to Atherosclerosis and Fatty Liver Disease—Postmortem ICP-MS Analysis of Selected Human Tissues

P. Portincasa, J. Flieger, D. Majerek, 2023, Nutrients.

Different Variation of Intra-familial Body Mass Index subjected to Covid-19 Lockdown.

P. Portincasa, F. Corbo, M. Faienza, 2022, Journal of gastrointestinal and liver diseases : JGLD.

Faculty Opinions recommendation of Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial).

P. Portincasa, 2018, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

The pros and cons of biological effects of herbs and herb-derived compounds on liver tumorigenesis

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2022, Hepatoma Research.

Prevention of oxidative stress and diseases by antioxidant supplementation.

P. Portincasa, A. D’Alessandro, G. Martemucci, 2022, Medicinal chemistry.

Phenotyping the obesities: reality or utopia?

G. Frühbeck, P. Portincasa, 2023, Reviews in Endocrine and Metabolic Disorders.

Modulation of cholesterol crystallization in bile. Implications for non-surgical treatment of cholesterol gallstone disease.

M. Vacca, G. Calamita, P. Portincasa, 2005, Current drug targets. Immune, endocrine and metabolic disorders.

Pathobiology of cholesterol gallstone disease: from equilibrium ternary phase diagram to agents preventing cholesterol crystallization and stone formation.

G. Calamita, P. Portincasa, A. Moschetta, 2003, Current drug targets. Immune, endocrine and metabolic disorders.

Liver disease: early signs you may be missing.

P. Portincasa, I. Grattagliano, G. Palasciano, 2009, The Journal of family practice.

Contribution of canalicular glutathione efflux to bile formation. From cholestasis associated alterations to pharmacological intervention to modify bile flow.

P. Portincasa, I. Grattagliano, G. Palasciano, 2005, Current drug targets. Immune, endocrine and metabolic disorders.

The interaction of bile acids and gut inflammation influences the pathogenesis of inflammatory bowel disease

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2023, Internal and Emergency Medicine.

Nuclear and chromatin rearrangement associate to epigenome and gene expression changes in a model of in vitro adipogenesis and hypertrophy.

A. Diaspro, P. Portincasa, L. Vergani, 2023, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Extent and features of liver steatosis in vitro pave the way to endothelial dysfunction without physical cell-to-cell contact.

P. Portincasa, L. Vergani, Francesca Baldini, 2021, NMCD. Nutrition Metabolism and Cardiovascular Diseases.

Effects of MBOAT7 polymorphism and steatosis on liver function assessed by methacetin breath test

M. Krawczyk, P. Portincasa, L. Bonfrate, 2023, European journal of clinical investigation.

The Biliary System: Second Edition

B. Neuschwander‐Tetri, P. Portincasa, D. Q. Wang, 2016 .

Bile Acids and Cancer: Direct and Environmental-Dependent Effects.

G. Calamita, P. Portincasa, V. Palmieri, 2017, Annals of hepatology.

Consequences of Disturbing Manganese Homeostasis

P. Portincasa, J. Flieger, G. Buszewicz, 2023, International journal of molecular sciences.

Therapeutic reflections in cholesterol homeostasis and gallstone disease: a review.

P. Portincasa, G. Garruti, I. Grattagliano, 2014, Current medicinal chemistry.

MITOCHONDRIA TARGETING TO OPPOSE THE PROGRESSION OF NONALCOHOLIC FATTY LIVER DISEASE

G. Frühbeck, P. Portincasa, M. Wieckowski, 2021 .

Altered membrane glycoprotein targeting in cholestatic hepatocytes

G. Calamita, P. Portincasa, M. Mastrodonato, 2010, European journal of clinical investigation.

MicroRNA in colorectal cancer: new perspectives for diagnosis, prognosis and treatment.

P. Portincasa, M. Rotelli, D. Altomare, 2013, Journal of gastrointestinal and liver diseases : JGLD.

The fatty liver as testimonial of systemic diseases. Further evidence from rheumatoid arthritis and confirmation for a leading role of internal medicine.

P. Portincasa, L. Bonfrate, A. Di Ciaula, 2023, European journal of internal medicine.

Models of non-Alcoholic Fatty Liver Disease and Potential Translational Value: the Effects of 3,5-L-diiodothyronine.

P. Portincasa, L. Vergani, L. Canesi, 2017, Annals of hepatology.

Gut microbes in metabolic disturbances. Promising role for therapeutic manipulations?

P. Portincasa, G. Garruti, L. Bonfrate, 2023, European journal of internal medicine.

Randomized trial of chronic supplementation with a nutraceutical mixture to subjects with Non Alcoholic Fatty Liver Disease (NAFLD)

S. Costanzo, G. Gaetano, A. Castelnuovo, 2019 .

Management of gallstones and its related complications

P. Portincasa, G. Garruti, A. Ciaula, 2016, Expert review of gastroenterology & hepatology.

Use of GELSECTAN® in Patients with Irritable Bowel Syndrome (IBS): an Italian Experience

M. Bellini, P. Portincasa, L. Bonfrate, 2021, Patient preference and adherence.

Impact of adipokines and myokines on fat browning

G. Frühbeck, P. Portincasa, V. Catalán, 2020, Journal of Physiology and Biochemistry.

Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol

B. Neuschwander‐Tetri, P. Portincasa, G. Garruti, 2013, European journal of clinical investigation.

Liver function as assessed by breath tests in patients with hepatocellular carcinoma.

P. Portincasa, I. Grattagliano, G. Palasciano, 2009, The Journal of surgical research.

Coordinate regulation of gallbladder motor function in the gut‐liver axis

P. Portincasa, A. Moschetta, K. V. van Erpecum, 2008, Hepatology.

The Pivotal Role of Microbiota in Obesity

P. Portincasa, L. Bonfrate, 2015 .

Effects of simvastatin and cholestyramine on bile lipid composition and gall bladder motility in patients with hypercholesterolaemia.

P. Portincasa, K. V. van Erpecum, G. P. van Berge‐Henegouwen, 1995, Gut.

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia.

P. Mazzanti, C. Mussi, D. Cucinotta, 2020, Journal of the American Medical Directors Association.

Water channel proteins in bile formation and flow in health and disease: when immiscible becomes miscible.

G. Calamita, P. Portincasa, 2012, Molecular aspects of medicine.