C. Blancher

发表

The genetic architecture of type 2 diabetes

Stephen C. J. Parker, Taylor J. Maxwell, Mauricio O. Carneiro, 2016, Nature.

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

D. Gauguier, J. Trygg, J. Lindon, 2005, Analytical chemistry.

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

M. McCarthy, D. Gauguier, J. Lindon, 2006, Proceedings of the National Academy of Sciences.

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Mauricio O. Carneiro, Tanya M. Teslovich, Kyle J. Gaulton, 2017, Diabetes.

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

Tom R. Gaunt, P. Elliott, P. Tsai, 2016, Nature.

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.

Tom R. Gaunt, P. Elliott, M. Jarvelin, 2015, The lancet. Diabetes & endocrinology.

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

Jiannis Ragoussis, Richard R. Copley, J. Ragoussis, 2009, The Journal of Biological Chemistry.

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

E. O’Neill, D. Vavoulis, C. Verrill, 2020, bioRxiv.

The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target

A. Harris, C. Blancher, 1998, Cancer and Metastasis Reviews.

ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix

I G Campbell, C. Blancher, I. Campbell, 2006, Oncogene.

Cloning and characterization of a novel transcription factor involved in cellular proliferation arrest: PATF

A. Mamoune, C. Blancher, B. Néron, 2001, Oncogene.

Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control

Julian E. Fuchs, R. Glen, D. Gauguier, 2018, bioRxiv.

Association of ARNT splice variants with estrogen receptor-negative breast cancer, poor induction of vascular endothelial growth factor under hypoxia, and poor prognosis.

A. Harris, S. Safe, C. Blancher, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

Borivoj Vojnovic, Mircea Ivan, Jiannis Ragoussis, 2010, PloS one.

The genetic architecture of type 2 diabetes

Stephen C. J. Parker, Taylor J. Maxwell, Mauricio O. Carneiro, 2016, Nature.

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

Nicola L. Beer, Pablo Cingolani, Mark I. McCarthy, 2015, PLoS genetics.

Sodium dodecyl sulphate-polyacrylamide denaturing gel electrophoresis and Western blotting techniques.

C. Blancher, Robert A. Mc Cormick, 2012, Methods in molecular biology.

SDS -PAGE and Western Blotting Techniques.

C. Blancher, A. Jones, 2001, Methods in molecular medicine.

Genome-wide association study identifies a novel variant in RAD51B associated with male breast cancer risk

A. Ashworth, S. Novaković, M. Zvelebil, 2012, Nature Genetics.

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

Dominique Gauguier, Jeremy K Nicholson, M. Bihoreau, 2007, Nature Genetics.

Nectinepsin: A New Extracellular Matrix Protein of the Pexin Family

C. Blancher, L. Bidou, B. Pessac, 1996, The Journal of Biological Chemistry.

The landscape of copy number variations in Finnish families with autism spectrum disorders

H. Lähdesmäki, G. Buck, Chakravarthi Kanduri, 2016, Autism research : official journal of the International Society for Autism Research.

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes.

E. O’Neill, D. Vavoulis, C. Verrill, 2021, Gastroenterology.

Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.

A. Harris, C. Blancher, John W. Moore, 2001, Cancer research.

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

M. Bihoreau, M. Farrall, H. Parving, 2009, BMC Medical Genomics.

The genome-wide landscape of copy number variations in the MUSGEN study provides evidence for a founder effect in the isolated Finnish population

H. Lähdesmäki, G. Buck, Chakravarthi Kanduri, 2013, European Journal of Human Genetics.

Genome-Wide Copy Number Variation Analysis in Extended Families and Unrelated Individuals Characterized for Musical Aptitude and Creativity in Music

H. Lähdesmäki, G. Buck, Chakravarthi Kanduri, 2013, PloS one.

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity Authors

Tom R. Gaunt, Christa, Federica, 2016 .

Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines.

A. Harris, C. Blancher, K. Talks, 2000, Cancer research.

Identification and Functional Characterization of G 6 PC 2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G 6 PC 2-ABCB 11 Locus

Kyle J. Gaulton, Tanya, T. Spector, 2015 .

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice

J. K. Nicholson, M. I. McCarthy, M. McCarthy, 2007, Diabetologia.

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

Quan Gu, Jeremy K. Nicholson, Dominique Gauguier, 2017, Cell reports.

Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice

D. Gauguier, S. Wilder, J. Nicholson, 2008, PloS one.

Epigenome-wide association reveals extensive perturbations in DNA methylation associated with adiposity and its adverse metabolic consequences. Authors

Tom R. Gaunt, P. Elliott, M. Jarvelin, 2015 .

Glycomics investigation into insulin action.

S. Richardson, D. Gauguier, K. Siddle, 2006, Biochimica et biophysica acta.

A novel cDNA corresponding to transcripts expressed in retina post-mitotic neurons

C. Blancher, L. Bidou, B. Pessac, 1993, Mechanisms of Development.

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Taesung Park, Christian Gieger, Tien Yin Wong, 2017, Scientific Data.

Universal latent axes capturing Parkinson’s patient deep phenotypic variation reveals patients with a high genetic risk for Alzheimer’s disease are more likely to develop a more aggressive form of Parkinson’s

J. Marchini, C. Webber, N. Williams, 2019, bioRxiv.

Submitted 28/12/18 Title: Universal continuous severity traits underlying hundreds of Parkinson’s disease clinical features Short running title: Parkinson’s disease phenotypic axes

C. Webber, N. Williams, C. Sandor, 2019 .

Retinal dysplasia in mice lacking p56lck

C. Blancher, B. Pessac, B. Néron, 1998, Oncogene.

The landscape of copy number variations in Finnish families with autism spectrum disorders

H. Lähdesmäki, G. Buck, Chakravarthi Kanduri, 2016, Autism research : official journal of the International Society for Autism Research.