T. Madhusudhan

发表

The emerging role of coagulation proteases in kidney disease

T. Madhusudhan, B. Kerlin, B. Isermann, 2016, Nature Reviews Nephrology.

An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor.

T. Madhusudhan, B. Isermann, J. Oldenburg, 2009, Chemistry & biology.

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy.

T. Madhusudhan, B. Isermann, Hongjie Wang, 2017, Journal of the American Society of Nephrology : JASN.

Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy

T. Madhusudhan, B. Isermann, Hongjie Wang, 2015, Nature Communications.

nephropathy podocyte apoptosis: protective effect of factor V Leiden in diabetic Low but sustained coagulation activation ameliorates glucose-induced

T. Madhusudhan, B. Isermann, Hongjie Wang, 2014 .

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

K. Reymann, T. Madhusudhan, B. Isermann, 2014, Kidney international.

Nuclear Factor Erythroid-derived 2 (Nfe2) Regulates JunD DNA-binding Activity via Acetylation

T. Madhusudhan, B. Isermann, Hongjie Wang, 2011, The Journal of Biological Chemistry.

Human RAGE antibody protects against AGE-mediated podocyte dysfunction.

T. Madhusudhan, B. Isermann, M. Zeier, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation

T. Madhusudhan, Wen Dong, Y. Liu, 2021, International journal of biological sciences.

Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy.

T. Madhusudhan, B. Isermann, Hongjie Wang, 2016, Journal of the American Society of Nephrology : JASN.

protease-activated receptor-3 in podocytes Cytoprotective signaling by activated protein C requires

C. Esmon, J. Griffin, T. Madhusudhan, 2012 .

Pharmacologic IRE1α kinase inhibition alleviates aortic dissection by decreasing vascular smooth muscle cells apoptosis

T. Madhusudhan, Wanjun Liu, Xingwei He, 2022, International journal of biological sciences.

ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1

T. Madhusudhan, Tao Wang, Xingwei He, 2022, The Journal of biological chemistry.

Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis

C. Esmon, T. Madhusudhan, B. Isermann, 2007, Nature Medicine.

Podocyte Integrin-β 3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.

C. Esmon, T. Madhusudhan, B. Isermann, 2020, Journal of the American Society of Nephrology : JASN.

Coagulation Signalling and Metabolic Disorders: Lessons Learned from Animal Models

T. Madhusudhan, W. Ruf, 2018, Hämostaseologie.

Hypercoagulability Inhibits Monocyte Transendothelial Migration Through Protease-Activated Receptor-1–, Phospholipase-Cβ–, Phosphoinositide 3-Kinase–, and Nitric Oxide–Dependent Signaling in Monocytes and Promotes Plaque Stability

D. Frommhold, T. Madhusudhan, B. Isermann, 2009, Circulation.

Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy

T. Madhusudhan, Hongjie Wang, S. Karnati, 2022, Pharmaceuticals.

Lipid presentation by the protein C receptor links coagulation with autoimmunity

C. Esmon, K. Lackner, T. Madhusudhan, 2021, Science.

Negative Interactions and Feedback Regulations Are Required for Transient Cellular Response

Tilo Beyer, Burkhart Schraven, T. Madhusudhan, 2014, Scientific Reports.

Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes.

C. Esmon, J. Griffin, T. Madhusudhan, 2012, Blood.

The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition

T. Madhusudhan, B. Isermann, Hongjie Wang, 2012, Thrombosis and Haemostasis.

Homeostatic nuclear RAGE–ATM interaction is essential for efficient DNA repair

H. Hammes, P. Reynolds, S. Herzig, 2017, Nucleic acids research.

Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination.

C. Esmon, T. Madhusudhan, B. Isermann, 2015, Journal of the American Society of Nephrology : JASN.

Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target

N. Weissmann, T. Madhusudhan, S. Ergün, 2021, Frontiers in Cardiovascular Medicine.

Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc

K. Reymann, P. Pelicci, C. Esmon, 2012, Proceedings of the National Academy of Sciences.

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.

C. Esmon, T. Madhusudhan, B. Isermann, 2017, Blood.

Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy.

T. Madhusudhan, B. Isermann, Hongjie Wang, 2011, Blood.

Zhang et al. IRE1α inhibition alleviates AD by decreasing VSMCs apoptosis

T. Madhusudhan, H. Zeng, Shiliang Li, 2022 .

At the cutting edge: conformational PARtiality

T. Madhusudhan, B. Isermann, Berend Isermann, 2012, Journal of thrombosis and haemostasis : JTH.

Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy.

T. Madhusudhan, B. Isermann, Hongjie Wang, 2016, Journal of the American Society of Nephrology : JASN.

Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy.

T. Madhusudhan, B. Isermann, Hongjie Wang, 2011, Blood.

Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis

T. Madhusudhan, Tao Wang, Hongjie Wang, 2021, Frontiers in Cardiovascular Medicine.