J. Natarajan

发表

Knowledge Discovery in Biology and Biotechnology Texts: A Review of Techniques, Evaluation Strategies, and Applications

J. Natarajan, D. Berrar, C. Hack, 2005, Critical reviews in biotechnology.

Multi-targeted therapy for leprosy: insilico strategy to overcome multi drug resistance and to improve therapeutic efficacy.

J. Natarajan, Shanmugam Anusuya, 2012, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Leveraging big data bioinformatics approaches to extract knowledge from Staphylococcus aureus public omics data

J. Natarajan, D. Subramanian, Devika Subramanian, 2022, Critical reviews in microbiology.

Combination of site directed mutagenesis and secondary structure analysis predicts the amino acids essential for stability of M. leprae MurE

J. Natarajan, Anusuya Shanmugam, 2014, Interdisciplinary Sciences: Computational Life Sciences.

Classification and Domain Analysis of Protein Kinases in Hominids

J. Natarajan, Saranya Jayapalan, 2016 .

The eradication of leprosy: molecular modeling techniques for novel drug discovery

J. Natarajan, Shanmugam Anusuya, 2013, Expert opinion on drug discovery.

Text mining and network analysis to find functional associations of genes in high altitude diseases

Jeyakumar Natarajan, Devika Subramanian, Balu Bhasuran, 2018, Comput. Biol. Chem..

The potential role of procyanidin as a therapeutic agent against SARS-CoV-2: a text mining, molecular docking and molecular dynamics simulation approach

J. Natarajan, P. Kolandaivel, Balu Bhasuran, 2020, Journal of biomolecular structure & dynamics.

MicroRNA mediated network motifs in autoimmune diseases and its crosstalk between genes, functions and pathways.

J. Natarajan, Archana Prabahar, 2017, Journal of immunological methods.

Substrate specificities in Salmonella typhi outer membrane protease (PgtE) from Omptin family – An in silico proteomic approach

J. Natarajan, Gopinath Samykannu, P. Vijayababu, 2018 .

Genomic analysis of RNA-Seq and sRNA-Seq data identifies potential regulatory sRNAs and their functional roles in Staphylococcus aureus.

J. Natarajan, D. Subramanian, Balu Bhasuran, 2019, Genomics.

Computational Identification of Alzheimer's Disease Specific Transcription Factors using Microarray Gene Expression Data

J. Natarajan, V. Krishnamurthy, Nicy Sweety Issac, 2009 .

Salivary Biomarkers in Gastric Cancer: A Non-Invasive Biomarkers for Early Detection and Diagnostics

J. Natarajan, 2020, Advances in Cancer Research & Clinical Imaging.

Prioritization of potential drug targets and antigenic vaccine candidates against Klebsiella aerogenes using the computational subtractive proteome-driven approach

J. Natarajan, Anusuya Shanmugam, Vijina Chakkyarath, 2021, Journal of Proteins and Proteomics.

Computational identification and analysis of neurodegenerative disease associated protein kinases in hominid genomes

J. Natarajan, D. Subramanian, Saranya Jayapalan, 2016, Genes & diseases.

Network analysis of MicroRNA transcripts revealed relevant MicroRNAs and gene candidates for angiogenesis in gastric cancer

J. Natarajan, Anju R. Nath, 2020 .

Discovering mycobacterial lectins as potential drug targets and vaccine candidates for tuberculosis treatment: a theoretical approach

J. Natarajan, Shanmughavel Piramanayagam, Shobana Sundar, 2021, Journal of Proteins and Proteomics.

Multiscale Laplacian graph kernel combined with lexico-syntactic patterns for biomedical event extraction from literature

J. Natarajan, Balu Bhasuran, Sabenabanu Abdulkadhar, 2020, Knowledge and Information Systems.

Combination of site directed mutagenesis and secondary structure analysis predicts the amino acids essential for stability of M. leprae MurE

J. Natarajan, Anusuya Shanmugam, 2014, Interdisciplinary Sciences: Computational Life Sciences.

Synthesis, In Vitro Cytotoxicity, and DFT Studies of Novel 2‐Amino Substituted Benzonaphthyridines as PDK1 Inhibitors

J. Natarajan, R. Satheeshkumar, K. Prabha, 2022, ChemistrySelect.

In Silico Characterization of B Cell and T Cell Epitopes for Subunit Vaccine Design of Salmonella typhi PgtE: A Molecular Dynamics Simulation Approach

Jeyakumar Natarajan, Sundarabaalaji Narayanan, Gopinath Samykannu, 2019, J. Comput. Biol..

Screening of FDA-approved compound library identifies potential small-molecule inhibitors of SARS-CoV-2 non-structural proteins NSP1, NSP4, NSP6 and NSP13: molecular modeling and molecular dynamics studies

J. Natarajan, K. Sekar, Shanmughavel Piramanayagam, 2021, Journal of Proteins and Proteomics.

Functional gene clustering via gene annotation sentences, MeSH and GO keywords from biomedical literature

Jeyakumar Natarajan, Jawahar Ganapathy, J. Natarajan, 2007, Bioinformation.

A review on structural genomics approach applied for drug discovery against three vector-borne viral diseases: Dengue, Chikungunya and Zika

J. Natarajan, Shanmughavel Piramanayagam, Shobana Sundar, 2022, Virus Genes.

GalNAc-siRNA conjugates: Prospective tools on the frontier of anti-viral therapeutics

J. Natarajan, B. Balasubramanian, Shanmughavel Piramanayagam, 2021, Pharmacological Research.

Bioinformatics Applications in Fungal Siderophores: Omics Implications

J. Natarajan, Vijina Chakkyarath, Devika Subramanian, 2021 .

Prediction of microRNAs involved in immune system diseases through network based features

Jeyakumar Natarajan, Archana Prabahar, J. Natarajan, 2017, J. Biomed. Informatics.

EXPRESSION-BASED NETWORK BIOLOGY IDENTIFIES HIGH SCORE SUB-NETWORKS AND THEIR ROLES IN RETT SYNDROME

J. Natarajan, Saravanakumar Selvaraj, 2013 .

RNA-seq analysis reveals resistome genes and signalling pathway associated with vancomycin-intermediate Staphylococcus aureus

J. Natarajan, Devika Subramanian, 2019, Indian journal of medical microbiology.

Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

Jeyakumar Natarajan, Werner Dubitzky, Daniel P. Berrar, 2006, BMC Bioinformatics.

Text Mining Perspectives in Microarray Data Mining

Jeyakumar Natarajan, J. Natarajan, 2013 .

Automated Extraction and Visualization of Protein-Protein Interaction Networks and Beyond: A Text-Mining Protocol

Kalpana Raja, Jeyakumar Natarajan, Ian Ross, 2020, Protein-Protein Interaction Networks.

HPIminer: A text mining system for building and visualizing human protein interaction networks and pathways

Kalpana Raja, Jeyakumar Natarajan, Pankaj Moses Monickaraj, 2015, J. Biomed. Informatics.

The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer's disease

J. Natarajan, Saranya Jayapalan, 2013, Bioinformation.

Multiscale Laplacian graph kernel combined with lexico-syntactic patterns for biomedical event extraction from literature

Jeyakumar Natarajan, Sabenabanu Abdulkadhar, Balu Bhasuran, 2020, Knowl. Inf. Syst..

Classifying protein-protein interaction articles from biomedical literature using many relevant features and context-free grammar

Jeyakumar Natarajan, Sabenabanu Abdulkadhar, Gurusamy Murugesan, 2017, J. King Saud Univ. Comput. Inf. Sci..

Automatic extraction of gene-disease associations from literature using joint ensemble learning

Balu Bhasuran, Jeyakumar Natarajan, J. Natarajan, 2018, PloS one.

Distributed smoothed tree kernel for protein-protein interaction extraction from the biomedical literature

Jeyakumar Natarajan, Sabenabanu Abdulkadhar, Gurusamy Murugesan, 2017, PloS one.

BCC-NER: bidirectional, contextual clues named entity tagger for gene/protein mention recognition

Jeyakumar Natarajan, Sabenabanu Abdulkadhar, Balu Bhasuran, 2017, EURASIP J. Bioinform. Syst. Biol..

Stacked ensemble combined with fuzzy matching for biomedical named entity recognition of diseases

Jeyakumar Natarajan, Sabenabanu Abdulkadhar, Balu Bhasuran, 2016, J. Biomed. Informatics.

Integrated meta-analysis and machine learning approach identifies acyl-CoA thioesterase with other novel genes responsible for biofilm development in Staphylococcus aureus.

J. Natarajan, Devika Subramanian, 2020, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Text Mining of Full Text Articles and Creation of a Knowledge Base for Analysis of Microarray Data

Jeyakumar Natarajan, Werner Dubitzky, Yonghong Zhang, 2004, KELSI.

Microarray Data Analysis and Mining Tools

Jeyakumar Natarajan, J. Natarajan, Saravanakumar Selvaraj, 2011, Bioinformation.

Probing intermolecular interactions and binding stability of antimicrobial peptides with beta-lactamase of Klebsiella aerogenes by comparing FDA approved beta-lactam drugs: a docking and molecular dynamics approach

J. Natarajan, Vijina Chakkyarath, 2021, Journal of biomolecular structure & dynamics.

Molecular Mechanism of T-2 Toxin-Induced Cerebral Edema by Aquaporin-4 Blocking and Permeation

Balu Bhasuran, Jeyakumar Natarajan, Nikhil Maroli, 2019, J. Chem. Inf. Model..

Network analysis of S. aureus response to ramoplanin reveals modules for virulence factors and resistance mechanisms and characteristic novel genes.

J. Natarajan, Devika Subramanian, 2015, Gene.

Identification of Ideal Multi-targeting Bioactive Compounds Against Mur Ligases of Enterobacter aerogenes and Its Binding Mechanism in Comparison with Chemical Inhibitors

J. Natarajan, Vijina Chakkyarath, 2017, Interdisciplinary Sciences: Computational Life Sciences.

Mining protein phosphorylation information from biomedical literature using NLP parsing and Support Vector Machines

Kalpana Raja, Jeyakumar Natarajan, J. Natarajan, 2018, Comput. Methods Programs Biomed..

Virtual screening of phenylsulfonamido-3-morpholinopropan-2-yl dihydrogen phosphate derivatives as novel inhibitors of MurC–MurF ligases from Mycobacterium leprae

J. Natarajan, Anusuya Shanmugam, V. Anbazhagan, 2012, Medicinal Chemistry Research.

A Grid Infrastructure for Text Mining of Full Text Articles and Creation of a Knowledge Base of Gene Relations

Jeyakumar Natarajan, Werner Dubitzky, Eric G. Bremer, 2005, ISBMDA.

Overview of the interactive task in BioCreative V

Jeyakumar Natarajan, Shruti Rao, Zhiyong Lu, 2015, Database J. Biol. Databases Curation.

ProNormz - An integrated approach for human proteins and protein kinases normalization

Kalpana Raja, Jeyakumar Natarajan, Suresh Subramani, 2014, J. Biomed. Informatics.

HomoKinase: A Curated Database of Human Protein Kinases

Jeyakumar Natarajan, Suresh Subramani, J. Natarajan, 2013 .

Analysis of disordered regions in protein kinase subfamilies of Homo sapiens and Coenorhabditis elegans

J. Natarajan, K. Kurup, 2010 .

Distant Supervision for Large-Scale Extraction of Gene–Disease Associations from Literature Using DeepDive

Jeyakumar Natarajan, Balu Bhasuran, J. Natarajan, 2018, International Conference on Innovative Computing and Communications.

Analysis of Chromate Transporters in Bacterial Species for Cr(VI) Reduction Isolated from Tannery Effluent Contaminated Site of Dindigul District, Tamil Nadu, India

J. Natarajan, Prabagaran Solai Ramatchandirane, Devika Subramanian, 2021 .

A Long Short-Term Memory Deep Learning Network for MRI Based Alzheimer’s Disease Dementia Classification

J. Natarajan, B. Bhasuran, Sneha Mirulalini Gnanasegar, 2020 .

An overview of the BioCreative 2012 Workshop Track III: interactive text mining task

Jeyakumar Natarajan, Zhiyong Lu, K. Bretonnel Cohen, 2013, Database J. Biol. Databases Curation.

Identification of potent inhibitors for Salmonella typhimurium quorum sensing via virtual screening and pharmacophore modeling.

J. Natarajan, S. Mohamed, S. Gnanendra, 2013, Combinatorial chemistry & high throughput screening.

Molecular modeling and active site analysis of SdiA homolog, a putative quorum sensor for Salmonella typhimurium pathogenecity reveals specific binding patterns of AHL transcriptional regulators

J. Natarajan, Shanmugam Anusuya, S. Gnanendra, 2012, Journal of Molecular Modeling.

DisGeReExT: a knowledge discovery system for exploration of disease–gene associations through large-scale literature-wide analysis study

J. Natarajan, Balu Bhasuran, B. Bhasuran, 2023, Knowledge and Information Systems.

PPInterFinder—a mining tool for extracting causal relations on human proteins from literature

Kalpana Raja, Suresh Subramani, Jeyakumar Natarajan, 2013, Database J. Biol. Databases Curation.

Transcriptomic Approaches in Understanding SARS-CoV-2 Infection

J. Natarajan, Sona Charles, 2021, Integrated Omics Approaches to Infectious Diseases.

Homology modeling and docking analyses of M. leprae Mur ligases reveals the common binding residues for structure based drug designing to eradicate leprosy

J. Natarajan, Anusuya Shanmugam, 2012, Journal of Molecular Modeling.

Comparative modeling of UDP-N-acetylmuramoyl-glycyl-D-glutamate-2, 6-diaminopimelate ligase from Mycobacterium leprae and analysis of its binding features through molecular docking studies

J. Natarajan, Anusuya Shanmugam, 2011, Journal of Molecular Modeling.

Integrated regulatory network based on lncRNA-miRNA-mRNA-TF reveals key genes and sub-networks associated with dilated cardiomyopathy

Jeyakumar Natarajan, Sona Charles, J. Natarajan, 2021, Comput. Biol. Chem..

Pancreatic Lipase Related Protein 1 as a potential target in triglyceride breakdown: A molecular docking studies with in vitro appraisal

J. Natarajan, N. Das, Subrata Shaw, 2023, Results in Chemistry.

A hybrid named entity tagger for tagging human proteins/genes

J. Natarajan, Kalpana Raja, S. Subramani, 2014, Int. J. Data Min. Bioinform..

Design, Synthesis and Evaluation of Antimicrobial Database-Derived Peptides Against Drug-Resistant Gram-Positive and Gram-Negative Pathogens

J. Natarajan, Vijina Chakkyarath, Brindha Priyadarisini Venkatesan, 2021, International Journal of Peptide Research and Therapeutics.

Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease

J. Natarajan, Veerankutty Subaida Shafna Asmy, 2022, Genomics & informatics.

Screening of Mycobacterium tuberculosis genes as putative drug targets for treatment of HIV-TB and lung cancer-TB comorbidities: An in silico analysis

J. Natarajan, Shanmughavel Piramanayagam, Shobana Sundar, 2021 .

Phylogeny and domain examination of two-component regulatory systems across staphylococcal species

J. Natarajan, Devika Subramanian, 2017 .

SPP1, a potential therapeutic target and biomarker for lung cancer: functional insights through computational studies.

J. Natarajan, Arunkumar Malaisamy, Shanmughavel Piramanayagam, 2023, Journal of Biomolecular Structure and Dynamics.

A comprehensive review on human disease—causing bacterial proteases and their impeding agents

J. Natarajan, Shanmughavel Piramanayagam, Shobana Sundar, 2023, Archives of Microbiology.

Network analysis of S. aureus response to ramoplanin reveals modules for virulence factors and resistance mechanisms and characteristic novel genes.

J. Natarajan, Devika Subramanian, 2015, Gene.

Prediction of microRNAs involved in immune system diseases through network based features

J. Natarajan, Archana Prabahar, 2017, J. Biomed. Informatics.

MicroRNA mediated network motifs in autoimmune diseases and its crosstalk between genes, functions and pathways.

J. Natarajan, Archana Prabahar, 2017, JIM - Journal of Immunological Methods.

A hybrid text mining system for chemical entity recognition and classification using dictionary look-up and pattern matching @ BeCalm challenge evaluation workshop

J. Natarajan, Kalpana Raja, L. Tsoi, 2017 .

Literature Based Discovery (LBD): Towards Hypothesis Generation and Knowledge Discovery in Biomedical Text Mining

J. Natarajan, Balu Bhasuran, Gurusamy Murugesan, 2023, ArXiv.