R. Wallis

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Structural and functional aspects of complement activation by mannose-binding protein.

R. Wallis, 2002, Immunobiology.

Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway

R. Wallis, 2007, Immunobiology.

The Hemopexin and O-Glycosylated Domains Tune Gelatinase B/MMP-9 Bioavailability via Inhibition and Binding to Cargo Receptors*

R. Dwek, S. Moestrup, M. Wormald, 2006, Journal of Biological Chemistry.

Pathways of Complement Complexes of the Classical and Lectin Analogous Interactions in Initiating

Anthony H Keeble, J. Toth, Robert B Sim, 2009 .

Analogous Interactions in Initiating Complexes of the Classical and Lectin Pathways of Complement1

Anthony H Keeble, J. Toth, Robert B Sim, 2009, The Journal of Immunology.

Characterization and membrane assembly of the TatA component of the Escherichia coli twin-arginine protein transport system.

B. Wallace, B. Berks, R. Wallis, 2002, Biochemistry.

Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis

R. Wallis, P. Barthe, W. Vollmer, 2018, Cell reports.

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation

R. Wallis, D. Wright, S. Perkins, 2017, Structure.

Surface properties: Immune attack on nanoparticles.

Robert B Sim, R. Wallis, 2011, Nature nanotechnology.

H‐ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses

R. Wallis, D. Sexton, D. Armstrong-James, 2015, Immunology.

Site-directed conjugation of "clicked" glycopolymers to form glycoprotein mimics: binding to mammalian lectin and induction of immunological function.

S. Evans, Lei Tao, R. Wallis, 2007, Journal of the American Chemical Society.

Sequence-controlled multi-block glycopolymers via cu(0) mediated living radical polymerization

R. Wallis, D. Haddleton, Qiang Zhang, 2014 .

Structure-function mapping of BbCRASP-1, the key complement factor H and FHL-1 binding protein of Borrelia burgdorferi.

C. Ponting, F. Cordes, L. Goodstadt, 2006, International journal of medical microbiology : IJMM.

Microsoft Word-final manuscript.docx

S. Moestrup, J. B. Moeller, U. Holmskov, 2015 .

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role

R. Wallis, S. Fumagalli, M. Oggioni, 2020, Acta neuropathologica communications.

Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis

R. Wallis, P. Barthe, W. Vollmer, 2018, Cell reports.

The Crystal Structure of Pneumolysin at 2.0 Å Resolution Reveals the Molecular Packing of the Pre-pore Complex

Md. Arif Sheikh, P. Andrew, R. Wallis, 2015, Scientific Reports.

Light Scattering By Optically-Trapped Vesicles Affords Unprecedented Temporal Resolution Of Lipid-Raft Dynamics

B. Wood, P. Andrew, R. Wallis, 2017, Scientific Reports.

The effect of recombinant hirudin on arterial thrombosis.

R. Wallis, 1993, Advances in experimental medicine and biology.

Interactions of Candida tropicalis pH-related antigen 1 with complement proteins C3, C3b, factor-H, C4BP and complement evasion.

R. Wallis, H. Yesilkaya, U. Kishore, 2022, Immunobiology.

Synthetic glycopolypeptides as potential inhibitory agents for dendritic cells and HIV-1 trafficking.

R. Wallis, D. Haddleton, A. Heise, 2013, Macromolecular rapid communications.

Dendritic cell lectin-targeting sentinel-like unimolecular glycoconjugates to release an anti-HIV drug.

R. Wallis, D. Haddleton, Guosong Chen, 2014, Journal of the American Chemical Society.

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation

H. Kettenmann, R. Wallis, E. Weihe, 2009, Journal of neuroscience research.

High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein

R. Wallis, J. Geng, D. Haddleton, 2010, Journal of the American Chemical Society.

The site at which 4-iodoacetamidosalicylate reacts with glutamate dehydrogenases.

J. Holbrook, R. Wallis, P. A. Roberts, 1973, The Biochemical journal.

The reaction of a histidine residue in glutamate dehydrogenase with diethyl pyrocarbonate.

J. Holbrook, R. Wallis, 1973, The Biochemical journal.

The effect of modifying lysine-126 on the physical, catalytic and regulatory properties of bovine liver glutamate dehydrogenase.

J. Holbrook, R. Wallis, 1973, The Biochemical journal.

Dominant Effects of Mutations in the Collagenous Domain of Mannose-Binding Protein1

R. Wallis, 2002, The Journal of Immunology.

Sequence-controlled multi-block glycopolymers to inhibit DC-SIGN-gp120 binding.

R. Wallis, D. Haddleton, Qiang Zhang, 2013, Angewandte Chemie.

The lytic transglycosylase, LtgG, controls cell morphology and virulence in Burkholderia pseudomallei

R. Wallis, G. Mukamolova, M. Richards, 2019, Scientific Reports.

l‐Fucose prevention of renal ischaemia/reperfusion injury in Mice

R. Wallis, C. Farrar, S. Sacks, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

Md. Arif Sheikh, P. Gál, R. Wallis, 2013, Proceedings of the National Academy of Sciences.

Near-planar Solution Structures of Mannose-binding Lectin Oligomers Provide Insight on Activation of Lectin Pathway of Complement

R. Wallis, Ami Miller, S. Perkins, 2011, The Journal of Biological Chemistry.

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation.

R. Wallis, P. Moody, A. Gingras, 2011, Structure.

Paths reunited: Initiation of the classical and lectin pathways of complement activation.

R. Wallis, R. Schmid, W. Schwaeble, 2010, Immunobiology.

Crystal structure of the CUB1‐EGF‐CUB2 region of mannose‐binding protein associated serine protease‐2

W. Weis, Joost C. M. Uitdehaag, R. Wallis, 2003, The EMBO journal.

Interaction of Mannose-binding Protein with Associated Serine Proteases

R. Wallis, R. Dodd, 2000, The Journal of Biological Chemistry.

Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97

P. Simpson, C. Robinson, P. Freemont, 2004, The EMBO journal.

High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus.

H. Randeva, H. Lehnert, Robert B Sim, 2011, Immunobiology.

Hirudins and the role of thrombin: lessons from leeches.

R. Wallis, 1988, Trends in pharmacological sciences.

Rationale for targeting complement in COVID‐19

R. Wallis, L. Klavinskis, C. Farrar, 2020, EMBO molecular medicine.

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

N. Samani, T. Fujita, R. Wallis, 2011, Proceedings of the National Academy of Sciences.

A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

Nilesh J Samani, Russell Wallis, Allan J Beveridge, 2012, Proteins.

Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN

H. Randeva, H. Lehnert, R. Wallis, 2017, Chemical science.

Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 2. Cognate and noncognate interactions that span the millimolar to femtomolar affinity range.

H Videler, A. Pommer, G. Moore, 1995, Biochemistry.

The structurome of a Clostridium difficile phage and the remarkable accurate prediction of its novel phage receptor-binding protein

T. Sicheritz-Pontén, Bent Petersen, R. Wallis, 2021, bioRxiv.

Identification of the receptor-binding protein of Clostridium difficile phage CDHS-1 reveals a new class of receptor-binding domains

R. Wallis, G. Xia, M. Clokie, 2021 .

An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria

R. Wallis, H. O’Hare, Wen Yin, 2018, mBio.

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation*

S. Moestrup, J. B. Moeller, U. Holmskov, 2015, The Journal of Biological Chemistry.

Syddansk Universitet Characterization of Microfibrillar-associated Protein 4 ( MFAP 4 ) as a Tropoelastin-and Fibrillin-binding Protein Involved in Elastic Fiber Formation

S. Moestrup, J. B. Moeller, U. Holmskov, 2015 .

Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome

R. Wallis, P. Moody, A. Gingras, 2015, BMC Biology.

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

P. Andrew, T. Fujita, Y. Endo, 2012, PLoS pathogens.

Lectin pathway effector enzyme mannan‐binding lectin‐associated serine protease‐2 can activate native complement C3 in absence of C4 and/or C2

P. Andrew, T. Fujita, Robert B Sim, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Molecular Determinants of Oligomer Formation and Complement Fixation in Mannose-binding Proteins*

R. Wallis, K. Drickamer, Kurt Drickamer, 1999, The Journal of Biological Chemistry.

Stoichiometry of Complexes between Mannose-binding Protein and Its Associated Serine Proteases

R. Wallis, Ce-Belle Chen, 2001, The Journal of Biological Chemistry.

Localization and Characterization of the Mannose-Binding Lectin (MBL)-Associated-Serine Protease-2 Binding Site in Rat Ficolin-A: Equivalent Binding Sites within the Collagenous Domains of MBLs and Ficolins1

R. Wallis, K. Reid, A. Dodds, 2007, The Journal of Immunology.

Mannose-Binding Lectins Associated with MASP-2 Autoactivation in Variant Decoupling of Carbohydrate Binding and

B. Reid, Wilhelm J. Schwaeble, Russell Wallis, 2013 .

Decoupling of Carbohydrate Binding and MASP-2 Autoactivation in Variant Mannose-Binding Lectins Associated with Immunodeficiency1

R. Wallis, K. Reid, N. Lynch, 2005, The Journal of Immunology.

Simultaneous Activation of Complement and Coagulation by MBL-Associated Serine Protease 2

A. Krarup, P. Gál, Robert B Sim, 2007, PloS one.

The Recognition Unit of FIBCD1 Organizes into a Noncovalently Linked Tetrameric Structure and Uses a Hydrophobic Funnel (S1) for Acetyl Group Recognition*

S. Moestrup, J. B. Moeller, U. Holmskov, 2009, The Journal of Biological Chemistry.

Protein Collagenous Domain of Mannose-Binding Dominant Effects of Mutations in the Russell Wallis

R. Wallis, 2002 .

Molecular defects in variant forms of mannose-binding protein associated with immunodeficiency.

R. Wallis, J. Cheng, 1999, Journal of immunology.

Mannan binding lectin‐associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells

K. Shakesheff, R. Wallis, R. Brown, 2013, Clinical and experimental immunology.

Tandem overproduction and characterisation of the nuclease domain of colicin E9 and its cognate inhibitor protein Im9.

G. Moore, C. Kleanthous, R. Wallis, 1994, European journal of biochemistry.

Explorer Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP 1 domain

R. Wallis, Ashfaq Ghumraa, Ahmed Razaa, 2017 .

Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain

D. Czajkowsky, R. Wallis, J. Rowe, 2015, Molecular and biochemical parasitology.

Title: Identification of the Minimal Binding Region of a Plasmodium Falciparum Igm Binding Pfemp1 Domainidentification of the Minimal Binding Region of a Plasmodium Falciparum Igm Binding Pfemp1 Domain.molecular and Biochemical Parasitology Identification of the Minimal Binding Region of a Plasmodiu

D. Czajkowsky, R. Wallis, J. Rowe, 2015 .

Conformational changes in the AAA ATPase p97–p47 adaptor complex

R. Isaacson, P. Freemont, J. Ladbury, 2006, The EMBO journal.

Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein.

R. Wallis, K. Drickamer, 1997, The Biochemical journal.

Crystal structure of an inulosucrase from Halalkalicoccus jeotgali B3T, a halophilic archaeal strain

R. Wallis, T. Pijning, M. A. Ghauri, 2021, The FEBS journal.

Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1.

R. Wallis, H. Yesilkaya, U. Kishore, 2022, Immunobiology.

Localization of MASP-2 binding site in rat ficolin-A: Equivalent binding sites in MBLs and ficolins

R. Wallis, K. Reid, A. Dodds, 2007 .

Two Mechanisms for Mannose-binding Protein Modulation of the Activity of Its Associated Serine Proteases*

R. Wallis, Ce-Belle Chen, 2004, Journal of Biological Chemistry.

A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity.

H Videler, G. Moore, C. Kleanthous, 1998, The Biochemical journal.

Carbohydrate recognition and complement activation by rat ficolin-B

R. Wallis, D. Mitchell, U. V. Girija, 2010, European journal of immunology.

Complement in Infections

R. Wallis, Youssif M. Ali, N. Lynch, 2011 .

Impaired Secretion of Rat Mannose-Binding Protein Resulting from Mutations in the Collagen-Like Domain1

R. Wallis, Charles T. Heise, James Nicholls, 2000, The Journal of Immunology.

Lysyl Hydroxylase 3 Modifies Lysine Residues to Facilitate Oligomerization of Mannan-Binding Lectin

U. Bergmann, R. Wallis, R. Myllylä, 2014, PloS one.

Localization of the Serine Protease-binding Sites in the Collagen-like Domain of Mannose-binding Protein

R. Wallis, K. Drickamer, J. Uitdehaag, 2004, Journal of Biological Chemistry.

Structure of the C1r–C1s interaction of the C1 complex of complement activation

R. Wallis, P. Moody, Farah Badakshi, 2018, Proceedings of the National Academy of Sciences.

Reply to Mortensen et al.: The zymogen form of complement component C1

R. Wallis, P. Moody, Farah Badakshi, 2018, Proceedings of the National Academy of Sciences.

Molecular Interactions between MASP-2, C4, and C2 and Their Activation Fragments Leading to Complement Activation via the Lectin Pathway*

Robert B Sim, R. Wallis, K. Reid, 2007, Journal of Biological Chemistry.

Specificity in protein-protein recognition: conserved Im9 residues are the major determinants of stability in the colicin E9 DNase-Im9 complex.

C. Kleanthous, R. Wallis, G. Moore, 1998, Biochemistry.

Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?

R. Dwek, Robert B Sim, R. Wallis, 2006, The Journal of biological chemistry.

In vivo and in vitro characterization of overproduced colicin E9 immunity protein.

C. Kleanthous, R. Wallis, G. Moore, 1992, European journal of biochemistry.

Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 1. Diffusion-controlled association and femtomolar binding for the cognate complex.

G. Moore, C. Kleanthous, R. Wallis, 1995, Biochemistry.

Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain

D. Czajkowsky, R. Wallis, A. Raza, 2015, Molecular and Biochemical Parasitology.

MBLs and Ficolins Sites within the Collagenous Domains of Site in Rat Ficolin-A : Equivalent Binding ( MBL )-Associated-Serine Protease-2 Binding Mannose-Binding Lectin Localization and Characterization of the Roscher ,

R. Wallis, K. Reid, A. Dodds, 2007 .

Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP 1 domain

R. Wallis, Ashfaq Ghumraa, Ahmed Razaa, 2015 .

Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP 1 domain

R. Wallis, Ashfaq Ghumraa, Ahmed Razaa, 2015 .

Engineering Novel Complement Activity into a Pulmonary Surfactant Protein*

J. Toth, R. Wallis, W. Schwaeble, 2010, The Journal of Biological Chemistry.

Engineering Complement Activity into a Pulmonary-surfactant Protein 1

J. Toth, R. Wallis, W. Schwaeble, 2009 .

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation*

S. Moestrup, J. B. Moeller, U. Holmskov, 2015, The Journal of Biological Chemistry.

A novel fold for the factor H–binding protein BbCRASP-1 of Borrelia burgdorferi

F. Cordes, P. Zipfel, P. Roversi, 2005, Nature Structural &Molecular Biology.

Structure‐function analysis for the development of peptide inhibitors for a Gram‐positive quorum sensing system

P. Andrew, R. Wallis, I. T. Abdullah, 2022, Molecular microbiology.

Formation of pre-pore complexes of pneumolysin is accompanied by a decrease in short-range order of lipid molecules throughout vesicle bilayers

P. Andrew, R. Wallis, A. J. Hudson, 2020, Scientific Reports.

Interaction of Mannan Binding Lectin with α2 Macroglobulin via Exposed Oligomannose Glycans

R. Dwek, Robert B Sim, R. Wallis, 2006, Journal of Biological Chemistry.