S. Pillai

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Cellular and Molecular Immunology

A. Abbas, A. Lichtman, S. Pillai, 1991 .

IgG4-related disease

J. Stone, S. Pillai, Y. Zen, 2015, The Lancet.

IgG4-related disease.

J. Stone, V. Deshpande, S. Pillai, 2014, Annual review of pathology.

Viewing Siglecs through the lens of tumor immunology

S. Pillai, Isabella Fraschilla, Isabella Fraschilla, 2017, Immunological reviews.

Naive recirculating B cells mature simultaneously in the spleen and bone marrow.

S. Pillai, Haoyuan Liu, P. Russell, 2007, Blood.

Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis

M. Whitfield, S. Pillai, D. Khanna, 2021, Arthritis Research & Therapy.

Molecular cloning of a human macrophage lectin specific for galactose.

S. Pillai, B. Cherayil, C. Wong, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the murine Mac-2 gene. Splice variants encode proteins lacking functional signal peptides.

S. Pillai, C. Chiodino, I. Rosenberg, 1993, The Journal of biological chemistry.

Activation of bone marrow–resident memory T cells by circulating, antigen-bearing dendritic cells

M. Starnbach, R. Bonasio, C. Halin, 2005, Nature Immunology.

The follicular versus marginal zone B lymphocyte cell fate decision

S. Pillai, A. Cariappa, 2009, Nature Reviews Immunology.

Marginal zone B cells.

S. Pillai, A. Cariappa, Stewart T. Moran, 2005, Annual review of immunology.

Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation in WEHI 231 B cells.

S. Pillai, T. J. Kim, L. Chen, 1998, Molecular immunology.

Birth pangs: the stressful origins of lymphocytes.

S. Pillai, 2005, The Journal of clinical investigation.

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

M. Altfeld, B. Walker, N. Kelleher, 2016, Mucosal Immunology.

Predictors of disease relapse in IgG4-related disease following rituximab.

J. Stone, Hyon K. Choi, V. Deshpande, 2016, Rheumatology.

Mer tyrosine kinase (MerTK) as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease.

J. Stone, S. Pillai, C. Doglioni, 2021, Rheumatology.

The Loss of Bcl-6 Expressing T Follicular Helper Cells and the Absence of Germinal Centers in COVID-19.

Kelsey K. Finn, B. Walker, Xu G. Yu, 2020, SSRN.

Suboptimal Humoral Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Viral Variant Generation

S. Pillai, 2021, Clinics in laboratory medicine.

Sub-optimal Humoral immunity in SARS CoV-2 infection and viral variant generation

S. Pillai, 2021, Clinics in Laboratory Medicine.

PROPERTIES AND OVERVIEW OF IMMUNE RESPONSES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

B lymphocytes directly contribute to tissue fibrosis in IgG4-Related Disease.

Simona Baghai Sain, J. Stone, M. Falconi, 2020, The Journal of allergy and clinical immunology.

ATP activation of protein degradation by extracts of crude and purified lysosomal preparations.

S. Pillai, J. Zull, 1985, Biochimica et biophysica acta.

Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management

D. Furst, E. Lee, S. Pillai, 2020, Annals of the Rheumatic Diseases.

DISEASES CAUSED BY IMMUNE RESPONSES: HYPERSENSITIVITY AND AUTOIMMUNITY

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Accelerated Proteasomal Degradation of Membrane Ig Heavy Chains1

S. C. Ho, S. Pillai, Subhra Chaudhuri, 2000, The Journal of Immunology.

Membrane anchoring of calnexin facilitates its interaction with its targets.

S. C. Ho, S. Pillai, M. Brenner, 1999, Molecular immunology.

The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene.

K. Isselbacher, J. Wands, S. Pillai, 1992, Proceedings of the National Academy of Sciences of the United States of America.

ANTIBODIES AND ANTIGENS

A. Abbas, A. Lichtman, S. Pillai, 2010 .

B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers

S. Pillai, A. Cariappa, V. Mahajan, 2020, Nature Communications.

ANTIGEN RECEPTORS AND ACCESSORY MOLECULES OF T LYMPHOCYTES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin.

K. Isselbacher, S. Pillai, I. Rosenberg, 1991, The Journal of biological chemistry.

EFFECTOR MECHANISMS OF CELL-MEDIATED IMMUNITY

A. Abbas, A. Lichtman, S. Pillai, 2010 .

The Activation and Differentiation of Mature T Lymphocytes

S. Pillai, 2000 .

M89V Sialic Acid Acetyl Esterase (SIAE) and All Other Non-Synonymous Common Variants of This Gene Are Catalytically Normal

S. Pillai, A. Cariappa, K. Taylor, 2013, PloS one.

Development of Peripheral B Cells or for The CD9 Tetraspanin Is Not Required for the

S. Pillai, Haoyuan Liu, C. Boucheix, 2017 .

The CD9 Tetraspanin Is Not Required for the Development of Peripheral B Cells or for Humoral Immunity1

S. Levy, S. Pillai, Haoyuan Liu, 2005, The Journal of Immunology.

THE MAJOR HISTOCOMPATIBILITY COMPLEX

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Effects of ATP, vanadate, and molybdate on cathepsin D-catalyzed proteolysis.

S. Pillai, J. Zull, 1985, The Journal of biological chemistry.

Two lymphoid roads diverge--but does antigen bade B cells to take the road less traveled?

S. Pillai, 2005, Immunity.

Positive selection and lineage commitment during peripheral B‐lymphocyte development

S. Pillai, A. Cariappa, Stewart T. Moran, 2004, Immunological reviews.

Antigen-dependent B-cell development.

S. Pillai, A. Cariappa, 2002, Current opinion in immunology.

Immunoglobulin transport in B cell development.

S. Pillai, 1991, International review of cytology.

S. Mallal, J. Stone, J. Meiler, 2019, Molecular genetics & genomic medicine.

Circulating Th2 memory cells in IgG4‐related disease are restricted to a defined subset of subjects with atopy

J. Stone, S. Pillai, E. Della-Torre, 2014, Allergy.

Clonally expanded cytotoxic CD4+ T cells and the pathogenesis of IgG4-related disease

J. Stone, S. Pillai, H. Mattoo, 2017, Autoimmunity.

Case Records of the Massachusetts General Hospital. Case 31-2016. A 53-Year-Old Man with Diplopia, Polydipsia, and Polyuria.

J. Stone, V. Deshpande, S. Pillai, 2016, The New England journal of medicine.

Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations

J. Stone, V. Deshpande, S. Pillai, 2014, Annals of the rheumatic diseases.

Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells

S. Pittaluga, V. Kanderova, L. Notarangelo, 2022, Nature Immunology.

Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes.

D. Sgroi, C. Boboila, S. Pillai, 2007, Journal of immunology.

The effects of vanadate and molybdate on cathepsin D; relationship to ATP activation of lysosomal proteolysis.

S. Pillai, J. Zull, 1985, Cell biology international reports.

A Catalytically Inactive Form of Protein Kinase C-Associated Kinase/Receptor Interacting Protein 4, a Protein Kinase Cβ-Associated Kinase That Mediates NF-κB Activation, Interferes with Early B Cell Development1

S. Pillai, A. Cariappa, M. Tang, 2003, The Journal of Immunology.

Myristoylation and the post-translational acquisition of hydrophobicity by the membrane immunoglobulin heavy-chain polypeptide in B lymphocytes.

D. Baltimore, S. Pillai, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Development of Peripheral B Cells or for The CD9 Tetraspanin Is Not Required for the

S. Pillai, Haoyuan Liu, C. Boucheix, 2017 .

Editorial: Cytotoxic CD4+ T Cells in Viral Infections

J. Zaunders, S. Pillai, Chansavath Phetsouphanh, 2017, Frontiers in Immunology.

JAKing up resistance to immunotherapy

S. Pillai, Faisal Alsufyani, 2017, Science Immunology.

Regulation of Nuclear Localization and Transcriptional Activity of TFII-I by Bruton’s Tyrosine Kinase

S. Pillai, A. Roy, C. Novina, 1999, Molecular and Cellular Biology.

Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome.

H. Kayserili, S. Pillai, A. Cansu, 2012, American journal of human genetics.

CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease.

N. Yosef, J. Stone, Xiuwei Zhang, 2020, The Journal of allergy and clinical immunology.

Tetrameric cell-surface MHC class I molecules

P. Benaroch, S. Pillai, Sudhir Krishna, 1992, Nature.

ACTIVATION OF T LYMPHOCYTES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Preferential expansion of cross-reactive pre-existing switched memory B cells that recognize the SARS-CoV-2 Omicron variant Spike protein

S. Pillai, V. Naranbhai, A. Balazs, 2022, medRxiv.

Clonal expansion of CD4 + Cytotoxic T Lymphocytes in IgG4-related disease

Jefte M. Drijvers, J. Stone, V. Deshpande, 2016 .

Neutralizing Anti-Interleukin-1 Receptor-Antagonist Autoantibodies Induce Inflammatory and Fibrotic Mediators in IgG4-Related Disease.

J. Stone, W. Robinson, S. Pillai, 2021, The Journal of allergy and clinical immunology.

T Lymphocyte Development

S. Pillai, 2000 .

SARS-CoV-2 epitope-specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability

Michael D Healy, Kelsey K. Finn, Han Liu, 2022, Science Immunology.

The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

J. Stone, S. Pillai, Hidetaka Yamamoto, 2018, Life Science Alliance.

Treating life-threatening TAFRO syndrome with interleukin-1 inhibition.

S. Pillai, M. Ponzoni, M. Lanzillotta, 2021, European journal of internal medicine.

Protein kinase C-associated kinase is not required for the development of peripheral B lymphocyte populations.

C. Boboila, S. Pillai, J. Peschon, 2006, Molecular immunology.

Tec kinase pathways in lymphocyte development and transformation.

S. Pillai, Stewart T. Moran, 2002, Biochimica et biophysica acta.

CELLS AND TISSUES OF THE ADAPTIVE IMMUNE SYSTEM

A. Abbas, A. Lichtman, S. Pillai, 2010 .

NK T cells provide lipid antigen-specific cognate help for B cells

G. Besra, S. Pillai, M. Brenner, 2008, Proceedings of the National Academy of Sciences.

Cytotoxic CD4+ T cells in Fibrosing Mediastinitis linked to Histoplasma capsulatum

Cory, S. Pillai, G. Deepe, 2021 .

CD4+CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum

S. Pillai, J. Loyd, G. Deepe, 2020, The Journal of Immunology.

B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease

J. Stone, R. Chung, V. Deshpande, 2014, Annals of the rheumatic diseases.

Cytotoxic CD8+ T cells may be drivers of tissue destruction in Sjögren’s syndrome

J. Stone, S. Pillai, M. Moriyama, 2022, Scientific Reports.

Alterations in sialic-acid O-acetylation glycoforms during murine erythrocyte development

S. Pillai, I. Rosenberg, V. Mahajan, 2018, bioRxiv.

Chapter 121 – IgG4-Related Disease

J. Stone, S. Pillai, 2017 .

The Development of Natural Killer Cells

S. Pillai, 2000 .

The major histocompatibility complex class I antigen-binding protein p 88 is the product of the calnexin gene ( human calneidn / chaperone / lmmngbuflns / endoplauic reiculm )

K. Isselbacher, J. Wands, S. Pillai, 2022 .

Polymorphisms involving the transmembrane domains of human TAP2

K. Isselbacher, S. Pillai, Y. Aoki, 2004, Immunogenetics.

ATP activation of parathyroid hormone cleavage catalyzed by cathepsin D from bovine kidney.

S. Pillai, J. Zull, R. Botti, 1983, The Journal of biological chemistry.

Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19

Gaurav D. Gaiha, B. Walker, M. Lichterfeld, 2021, medRxiv.

The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development

J. Avruch, Dawang Zhou, S. Pillai, 2018, Front. Immunol..

Neutralizing anti–IL-1 receptor antagonist autoantibodies induce inflammatory and fibrotic mediators in IgG4-related disease

Han Liu, J. Stone, W. Robinson, 2021 .

Esterases and autoimmunity: the sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance.

S. Pillai, A. Cariappa, Stephan P. Pirnie, 2009, Trends in immunology.

The omega/lambda 5 surrogate immunoglobulin light chain is expressed on the surface of transitional B lymphocytes in murine bone marrow

S. Pillai, B. Cherayil, 1991, The Journal of experimental medicine.

A Lymphocyte-specific Ltk Tyrosine Kinase Isoform Is Retained in the Endoplasmic Reticulum in Association with Calnexin*

S. C. Ho, S. Pillai, A. Snijders, 1997, The Journal of Biological Chemistry.

Tyrosine phosphorylation of Blk and Fyn Src homology 2 domain-binding proteins occurs in response to antigen-receptor ligation in B cells and constitutively in pre-B cells.

K. Isselbacher, S. Pillai, B. Cherayil, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The chosen few? Positive selection and the generation of naive B lymphocytes.

S. Pillai, Shiv Pillai, 1999, Immunity.

The Recirculating B Cell Pool Contains Two Functionally Distinct, Long-Lived, Posttransitional, Follicular B Cell Populations1

C. Boboila, S. Pillai, Haoyuan Liu, 2007, The Journal of Immunology.

Defective proliferative responses in B lymphocytes and thymocytes that lack neurofibromin.

T. Jacks, S. Pillai, J. Iacomini, 2002, Molecular immunology.

LYMPHOCYTE DEVELOPMENT AND THE REARRANGEMENT AND EXPRESSION OF ANTIGEN RECEPTOR GENES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Turning Charon around on the Styx?

S. Pillai, H. Allard-Chamard, 2017, Science Immunology.

Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes.

U. V. von Andrian, S. Pillai, Haoyuan Liu, 2005, Immunity.

Neutrophil Profiles of Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children

M. Sade-Feldman, W. Haas, G. Alter, 2022, Cell Reports Medicine.

bone marrow Naive recirculating B cells mature simultaneously in the spleen and

S. Pillai, Haoyuan Liu, P. Russell, 2013 .

Distinct intracellular fates of membrane and secretory immunoglobulin heavy chains in a pre-B cell line

S. Pillai, A. Bachhawat, 1991, The Journal of cell biology.

Suboptimal Humoral Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Viral Variant Generation

S. Pillai, 2021, Clinics in laboratory medicine.

Attenuated Cd8+ T Cell Activation and Infiltration of the Lungs in Severe COVID-19

B. Walker, Xu G. Yu, S. Pillai, 2021, SSRN Electronic Journal.

Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells.

S. Pillai, J. Zull, 1986, The Journal of biological chemistry.

J. Stone, V. Deshpande, S. Pillai, 2015, Arthritis & rheumatology.

Emerging Treatment Models in Rheumatology: IgG4‐Related Disease: Insights Into Human Immunology and Targeted Therapies

J. Stone, S. Pillai, Z. Wallace, 2017, Arthritis & rheumatology.

Emerging Treatment Models in Rheumatology: IgG4‐Related Disease: Insights Into Human Immunology and Targeted Therapies

J. Stone, S. Pillai, Z. Wallace, 2017, Arthritis & rheumatology.

Clinical features and mechanistic insights regarding IgG4-related dacryoadenitis and sialoadenitis: a review.

J. Stone, S. Pillai, S. Nakamura, 2019, International journal of oral and maxillofacial surgery.

Plasmablasts as a biomarker for IgG 4-related disease , independent of serum IgG 4 concentrations

J. Stone, V. Deshpande, S. Pillai, 2014 .

"ILC2 it, but I can't promise anything".

S. Pillai, D. Ditoro, 2022, Science immunology.

Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children

M. Sade-Feldman, W. Haas, G. Alter, 2022, Cell Reports Medicine.

The Mac-2 antigen is a galactose-specific lectin that binds IgE

S. Weiner, S. Pillai, B. Cherayil, 1989, The Journal of experimental medicine.

CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Surface transport and internalization of the membrane IgM H chain in the absence of the Mb-1 and B29 proteins.

S. Pillai, B. Cherayil, K. MacDonald, 1993, Journal of immunology.

The bone marrow perisinusoidal niche for recirculating B cells and the positive selection of bone marrow‐derived B lymphocytes

S. Pillai, A. Cariappa, 2009, Immunology and cell biology.

Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain.

A. Varki, R. Morris, S. Pillai, 2016, Cell reports.

Comprar Cellular and Molecular Immunology | Shiv Pillai | 9781416031222 | Saunders

A. Abbas, A. Lichtman, S. Pillai, 2007 .

Innate immunity.

S. Pillai, Shiv Pillai, Shiv Pillai, 1996, Current opinion in immunology.

Nondysenteric intestinal amebiasis colonic morphology and search forEntamoeba histolytica adherence and invasion

S. Pillai, W. Costerton, H. Ward, 1989, Digestive Diseases and Sciences.

Peripheral B cell subsets.

S. Pillai, D. Allman, 2008, Current opinion in immunology.

Galectins: A family of animal β-galactoside-binding lectins

Richard D. Cummings, Jun Hirabayashi, Reuben Lotan, 1994, Cell.

B cells and autoimmunity.

S. Pillai, A. Cariappa, H. Mattoo, 2011, Current opinion in immunology.

SnapShot: COVID-19

Aditya Achanta, S. Pillai, J. Said, 2020, Cell.

Lesional CD4+ IFN-γ+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis

Jefte M. Drijvers, J. Stone, S. Pillai, 2016, Annals of the rheumatic diseases.

A unique B2 B cell subset in the intestine

S. Pillai, Y. Shimomura, H. Shi, 2008, The Journal of experimental medicine.

Histocompatibility Antigens and Transplant Rejection

S. Pillai, 2001 .

Rethinking mechanisms of autoimmune pathogenesis.

S. Pillai, 2013, Journal of autoimmunity.

Accelerated emigration of B lymphocytes in the Xid mouse.

S. Pillai, T. J. Kim, A. Cariappa, 1999, Journal of immunology.

Winning with the B team?

S. Pillai, Faisal Alsufyani, 2020, Science Immunology.

Now you know your ABCs.

S. Pillai, 2011, Blood.

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression

Capucine Van Rechem, G. Getz, J. Joung, 2015, Genes & development.

B lymphocytes and cancer: a love-hate relationship.

S. Pillai, Grace J. Yuen, Ezana Demissie, 2016, Trends in cancer.

Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes

S. Pillai, 2000 .

Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection

Aly A. Khan, S. Pillai, Donald Wolfgeher, 2021, Nature Communications.

Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection

Aly A. Khan, S. Pillai, Donald Wolfgeher, 2020 .

Integrating Current Thinking on Peripheral B-Cell Tolerance in Lupus

Jefte M. Drijvers, S. Pillai, 2016 .

Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis.

L. Notarangelo, J. Walter, Karin Chen, 2015, The Journal of allergy and clinical immunology.

SARS-CoV-2 viral load is associated with increased disease severity and mortality

Michael D Healy, Kelsey K. Finn, David A. Drew, 2020, Nature Communications.

Formation of disulphide-linked µ2ω2 tetramers in pre-B cells by the 18K ω-immunoglobulin light chain

D. Baltimore, S. Pillai, 1987, Nature.

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

Kelsey K. Finn, B. Walker, Xu G. Yu, 2020, Cell.

Molecular Mechanisms of Lymphocyte Apoptosis

S. Pillai, 2000 .

Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis

D. Plichta, H. Vlamakis, H. Lähdesmäki, 2021, Genome Medicine.

Network-based integration of epigenetic landscapes unveils molecular programs underlying human T follicular helper cell differentiation

Jishnu Das, S. Pillai, V. Mahajan, 2021, bioRxiv.

Synergism between NF-κB1/p50 and Notch2 during the Development of Marginal Zone B Lymphocytes1

D. Sgroi, C. Boboila, S. Pillai, 2007, The Journal of Immunology.

Surrogate Immunoglobulin Light Chain Is Expressed on the Surface of Transitional B Lymphocytes in Murine Bone Marrow

S. Pillai, B. Cherayil, 2003 .

The w / X 5 Surrogate Immunoglobulin Light Chain Is Expressed on the Surface of Transitional B Lymphocytes in Murine Bone Marrow By

S. Pillai, B. Cherayil, 2003 .

V(D)J Recombination and the Generation of Diversity

S. Pillai, 2000 .

B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma

M. Falconi, V. Deshpande, S. Pillai, 2020, Oncoimmunology.

De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease.

J. Stone, V. Deshpande, S. Pillai, 2014, The Journal of allergy and clinical immunology.

Identification of galectin‐3 as an autoantigen in patients with IgG4‐related disease

J. Stone, W. Haas, S. Pillai, 2019, The Journal of allergy and clinical immunology.

Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.

Jefte M. Drijvers, V. Deshpande, S. Pillai, 2016, The Journal of allergy and clinical immunology.

A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4‐Related Disease and Decreases Following Glucocorticoid Treatment

J. Stone, D. Lazarević, M. Falconi, 2018, Arthritis & rheumatology.

IgG 4 -Related Disease

J. Stone, S. Pillai, 2017 .

IgG4-related midline destructive lesion

J. Stone, V. Deshpande, S. Pillai, 2014, Annals of the rheumatic diseases.

Neutrophil Profiles of Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children

D. Irimia, M. Sade-Feldman, W. Haas, 2021, bioRxiv.

IκB Kinase β (IKBKB) Mutations in Lymphomas That Constitutively Activate Canonical Nuclear Factor κB (NFκB) Signaling*

J. Joung, D. Reyon, S. Pillai, 2014, The Journal of Biological Chemistry.

Nuclear Factor κb Is Required for the Development of Marginal Zone B Lymphocytes

Bruce H. Horwitz, S. Pillai, B. Horwitz, 2000, The Journal of experimental medicine.

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Annette Lee, P. Gregersen, T. Gillis, 2010, Nature.

Only pregnant moms can do it….

S. Pillai, 2022, Science immunology.

Sialic acids and autoimmune disease

S. Pillai, V. Mahajan, 2016, Immunological reviews.

Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19

Gaurav D. Gaiha, Han Liu, B. Walker, 2022, Clinical Immunology.

Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2

Michael D Healy, Kelsey K. Finn, Benjamin P. Roscoe, 2021, Science Immunology.

Association of Activated Phosphatidylinositol 3-Kinase with p120cbl in Antigen Receptor-ligated B Cells (*)

S. Pillai, Yong‐Tae Kim, Tae Jin Kim, 1995, The Journal of Biological Chemistry.

Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier.

D. Walt, W. Haas, R. Morris, 2021, The Journal of clinical investigation.

Idiopathic pulmonary fibrosis and systemic sclerosis: pathogenic mechanisms and therapeutic interventions

S. Pillai, H. Mattoo, 2021, Cellular and Molecular Life Sciences.

Induction of metabolic quiescence defines the transitional to follicular B cell switch

A. Shalek, R. Gerszten, J. Walter, 2019, Science Signaling.

Protein Kinase C-associated Kinase Can Activate NFκB in Both a Kinase-dependent and a Kinase-independent Manner*

S. Pillai, Yongkai Ow, Luojing Chen, 2003, Journal of Biological Chemistry.

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

Andrew D. Luster, Gordon J. Freeman, Christian Brander, 2009, Journal of Virology.

The omega and iota surrogate immunoglobulin light chains.

D. Baltimore, S. Pillai, D. Baltimore, 1988, Current topics in microbiology and immunology.

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8+ T Cell Compartment by Negatively Regulating Tonic TCR Triggering

D. Irvine, Sudha Kumari, S. Pillai, 2019, The Journal of Immunology.

Compléments : De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG 4 -related disease

J. Stone, V. Deshpande, S. Pillai, 2014 .

Siglecs and immune regulation.

S. Pillai, A. Cariappa, H. Mattoo, 2012, Annual review of immunology.

9-O-acetyl sialic acid levels identify committed progenitors of plasmacytoid dendritic cells.

W. Haining, K. Yates, S. Pillai, 2019, Glycobiology.

Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis.

J. Stone, S. Pillai, D. Khanna, 2020, The Journal of clinical investigation.

IMMUNITY TO TUMORS

A. Abbas, A. Lichtman, S. Pillai, 2010 .

ANTIGEN PROCESSING AND PRESENTATION TO T LYMPHOCYTES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C 57 BL / 6 Strain Citation Mahajan

A. Varki, R. Morris, S. Pillai, 2016 .

Suboptimal Humoral Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Viral Variant Generation

S. Pillai, 2021, Clinics in laboratory medicine.

IMMUNITY TO MICROBES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

B CELL ACTIVATION AND ANTIBODY PRODUCTION

A. Abbas, A. Lichtman, S. Pillai, 2010 .

SARS-CoV-2 vaccination washes away original antigenic sin

S. Pillai, 2022, Trends in Immunology.

LECTIN THAT BINDS IgE

S. Pillai, 1989 .

Response to SARS-CoV-2 Initial Series and Additional Dose Vaccine in Patients with Predominant Antibody Deficiency

Kristin E. Burke, A. Iafrate, S. Pillai, 2022, The Journal of Allergy and Clinical Immunology: In Practice.

T and B lymphocytes in fibrosis and systemic sclerosis.

S. Pillai, 2019, Current opinion in rheumatology.

Marginal Zone B Cell Development

S. Pillai, I. Rosenberg, Ezana Demissie, 2016 .

B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase

A. Varki, H. Takematsu, C. Boboila, 2009, The Journal of experimental medicine.

Protein Kinase C-associated Kinase (PKK), a Novel Membrane-associated, Ankyrin Repeat-containing Protein Kinase*

S. Pillai, A. Cariappa, Luojing Chen, 2001, The Journal of Biological Chemistry.

Abatacept in IgG4-related disease: a prospective, open-label, single-arm, single-centre, proof-of-concept study.

Han Liu, J. Stone, S. Pillai, 2021, The Lancet. Rheumatology.

Distinct disease-specific Tfh cell populations in two different fibrotic diseases: IgG4-related disease and Kimura's disease.

J. Stone, S. Pillai, Hidetaka Yamamoto, 2022, The Journal of allergy and clinical immunology.

Faculty Opinions recommendation of ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.

S. Pillai, 2003 .

Is it bad, is it good, or is IgG4 just misunderstood?

S. Pillai, 2023, Science Immunology.

Luring T cells into a gray area

S. Pillai, Faisal Alsufyani, 2019, Science Immunology.

Does the SARS-CoV-2 spike really have an Achilles heel?

S. Pillai, 2023, The Journal of clinical investigation.

Ig Knock-In Mice Producing Anti-Carbohydrate Antibodies: Breakthrough of B Cells Producing Low Affinity Anti-Self Antibodies1

S. Pillai, L. Benatuil, J. Iacomini, 2008, The Journal of Immunology.

Affinity Anti-Self Antibodies Breakthrough of B Cells Producing Low Anti-Carbohydrate Antibodies: Ig Knock-In Mice Producing

S. Pillai, L. Benatuil, J. Iacomini, 2008 .

Comprar Cellular and Molecular Immunology, Updated Edition, 6th Edition With STUDENT CONSULT Online Access | Abul K. Abbas | 9781416031239 | Saunders

A. Abbas, A. Lichtman, S. Pillai, 2009 .

Disease Severity Linked to Increase in Autoantibody Diversity in IgG4‐Related Disease

J. Stone, S. Pillai, Z. Wallace, 2020, Arthritis & rheumatology.

S. Pillai, C. Perugino, Hang Liu, 2020 .

Immune mechanisms of fibrosis and inflammation in IgG4-related disease.

S. Pillai, N. Kaneko, C. Perugino, 2019, Current opinion in rheumatology.

The Generation of Naive B Lymphocytes

S. Pillai, 2000 .

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

T. Ndung’u, S. Kazer, A. Shalek, 2018, Front. Immunol..

Individuals with IgG4-related Disease Do Not Have an Increased Frequency of the K409 Variant of IgG4 that Compromises Fab-arm Exchange

J. Stone, S. Pillai, V. Mahajan, 2014, The Journal of Rheumatology.

Faculty Opinions recommendation of p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.

S. Pillai, 2003 .

Tetramer data reinterpreted

P. Benaroch, S. Pillai, Sudhir Krishna, 1993, Nature.

Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes

K. Siminovitch, C. Amos, B. Bacon, 2012, Genes and Immunity.

Aiolos regulates B cell activation and maturation to effector state.

B. Morgan, S. Pillai, K. Georgopoulos, 1998, Immunity.

Prevalence of atopy, eosinophilia, and IgE elevation in IgG4‐related disease

J. Stone, S. Pillai, E. Della Torre, 2014, Allergy.

The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21.

S. Pillai, C. Parng, K. Georgopoulos, 2001, Immunity.

Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children

D. Irimia, W. Haas, G. Alter, 2022, Cell Reports Medicine.

Analysis of MHC class II DP, DQ and DR alleles in Crohn’s disease

D. Finkelstein, B. Sands, S. Pillai, 1998, Gut.

Commitment to a Lymphoid Fate

S. Pillai, 2000 .

Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

B. Walker, M. Lichterfeld, S. Pillai, 2023, Cell reports.

Naturally Occurring Disorders of Lymphocyte Development

S. Pillai, 2000 .

Recognition of Antigens

A. Abbas, A. Lichtman, S. Pillai, 2010 .

T-B Collaboration in Autoimmunity, Infection, and Transplantation.

S. Pillai, D. Ditoro, N. Murakami, 2023, Transplantation.

OP0167 B LYMPHOCYTES DIRECTLY CONTRIBUTE TO TISSUE FIBROSIS IN IGG4-RELATED DISEASE

J. Stone, M. Falconi, S. Pillai, 2019, Oral Presentations.

OP0204 Clonal Expansion of CD4+ Cytotoxic T Lymphocytes in IGG4-Related Disease

J. Stone, V. Deshpande, S. Pillai, 2016 .

Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial

Han Liu, S. Pillai, D. Zack, 2023, The Lancet Rheumatology.

Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

B. Walker, M. Lichterfeld, S. Pillai, 2023, Cell Reports.

ANTIGEN PROCESSING AND PRESENTATION TO T LYMPHOCYTES

A. Abbas, A. Lichtman, S. Pillai, 2010 .

Comprar Cellular and Molecular Immunology, International Edition, 7th Edition | Abul K. Abbas | 9780808924258 | Saunders

A. Abbas, A. Lichtman, S. Pillai, 2011 .

Love the one you're with: the HIV, B cell and TFH cell triangle

S. Pillai, 2013, Nature Medicine.

Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis

R. Lafyatis, S. Pillai, L. Tsoi, 2024, Nature communications.

The Enzyme-Linked Immunosorbent Assay: The Application of ELISA in Clinical Research

Jefte M. Drijvers, Imad M. Awan, Cory A. Perugino, 2016 .

Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis.

L. Notarangelo, J. Walter, Karin Chen, 2015, The Journal of allergy and clinical immunology.

Lymphocyte Homing and the Generation of Secondary Lymphoid Organs

S. Pillai, 2000 .