Robert Landsiedel

发表

A protocol to determine dermal absorption of xenobiotica through human skin in vitro

Eric Fabian, Franz Oesch, Katharina Ott, 2017, Archives of Toxicology.

t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials.

Thomas Hartung, Robert Landsiedel, Ellen K Silbergeld, 2011, ALTEX.

The 3Rs as a framework to support a 21st century approach for nanosafety assessment

Shareen H. Doak, Qasim Chaudhry, Robert Landsiedel, 2017 .

The way forward for risk assessment of nanomaterials in solid media.

Robert Landsiedel, Koen Oorts, Janeck J Scott-Fordsmand, 2016, Environmental pollution.

Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward.

Robert Landsiedel, Lan Ma-Hock, Hans-Juergen Haussmann, 2012, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Skin sensitisation--moving forward with non-animal testing strategies for regulatory purposes in the EU.

Silvia Casati, Robert Landsiedel, David Basketter, 2013, Regulatory toxicology and pharmacology : RTP.

Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh.

Robert Landsiedel, Susanne N Kolle, R. Landsiedel, 2020, Handbook of experimental pharmacology.

Integrated Testing Strategies (ITS) for safety assessment.

Thomas Hartung, Andreas Schepky, Mardas Daneshian, 2015, ALTEX.

A critical appraisal of existing concepts for the grouping of nanomaterials.

Reinhard Kreiling, Robert Landsiedel, Thomas Petry, 2014, Regulatory toxicology and pharmacology : RTP.

KnowTox: pipeline and case study for confident prediction of potential toxic effects of compounds in early phases of development

Miriam Mathea, Andrea Volkamer, Robert Landsiedel, 2020, Journal of Cheminformatics.

Genotoxicity investigations on nanomaterials

Franz Oesch, Robert Landsiedel, 2012, Archives of Toxicology.

A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment.

Jo Anne Shatkin, Eileen Kuempel, Robert Landsiedel, 2013, ACS nano.

Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.

Markus Schulz, Franz Oesch, Robert Landsiedel, 2009, Mutation research.

The impact of precision uncertainty on predictive accuracy metrics of non-animal testing methods.

Silke Gabbert, Robert Landsiedel, Maria Leontaridou, 2019, ALTEX.

Toxicological evaluation of Cd-based fluorescent nanoprobes by means of in vivo studies

Robert Landsiedel, Bennard van Ravenzwaay, Lan Ma-Hock, 2018, BiOS.

Automatic sorting of toxicological information into the IUCLID (International Uniform Chemical Information Database) endpoint-categories making use of the semantic search engine Go3R.

Thomas Wächter, Robert Landsiedel, Matthias Zschunke, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

Decision tree models to classify nanomaterials according to the DF4nanoGrouping scheme

Katarzyna Odziomek, Tomasz Puzyn, Andreas Luch, 2018, Nanotoxicology.

Using the Go3R Search Engine to Collect Toxicological Data and Three Rs-relevant Information for REACH Registration Dossiers

Barbara Grune, Thomas Wächter, Michael Schroeder, 2012 .

Go3R - Intelligent internet searches for alternatives to animal testing

Horst Spielmann, Barbara Grune, Michael Schroeder, 2009 .

Performance standards and alternative assays: practical insights from skin sensitization.

Silvia Casati, Judy Strickland, Robert Landsiedel, 2013, Regulatory toxicology and pharmacology : RTP.

Evaluation of Non-animal Methods for Assessing Skin Sensitisation Hazard: A Bayesian Value-of-Information Analysis

Silke Gabbert, Robert Landsiedel, Andrew P Worth, 2016, Alternatives to laboratory animals : ATLA.

Rationale and decision rules behind the ECETOC NanoApp to support registration of sets of similar nanoforms within REACH

Robert Landsiedel, Gemma Janer, Wendel Wohlleben, 2020, Nanotoxicology.

Improving Quality of In vitro Methods: A GIVIMP Certification Program

Robert Landsiedel, Susanne N. Kolle, Erin Hill, 2021, Toxicology Letters.

ChemBioSim: Enhancing Conformal Prediction of In Vivo Toxicity by Use of Predicted Bioactivities

Ulf Norinder, Johannes Kirchmair, Andrea Volkamer, 2021, J. Chem. Inf. Model..

Assessing Experimental Uncertainty in Defined Approaches: Borderline Ranges for In Chemico and In Vitro Skin Sensitization Methods Determined from Ring Trial Data

Robert Landsiedel, Andreas Natsch, Miriam Mathea, 2021 .

The borderline range of toxicological methods: Quantification and implications for evaluating precision.

Silke Gabbert, Katharina Ott, Robert Landsiedel, 2017, ALTEX.

Predictive Toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data

Oded Maimon, Robert Landsiedel, Roni Romano, 2013, Particle and Fibre Toxicology.

Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials

Antonio Marcomini, Robert Landsiedel, Araceli Sánchez Jiménez, 2015, International journal of environmental research and public health.

Read-across for Hazard Assessment: The Ugly Duckling is Growing Up

Robert Landsiedel, R. Landsiedel, W. Teubner, 2015, Alternatives to laboratory animals : ATLA.

Erratum to "Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies" [Regul. Toxicol. Pharmacol. (2012) 402-414].

Robert Landsiedel, Annette Mehling, Bennard van Ravenzwaay, 2013, Regulatory toxicology and pharmacology : RTP.

Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.

Robert Landsiedel, Lynn L Bergeson, Vicki Stone, 2015, ACS nano.

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I): Phase I xenobiotic metabolism in human skin and in vitro skin models

Jean Krutmann, Robert Landsiedel, Ellen Fritsche, 2012 .

Elastic CNT-polyurethane nanocomposite: synthesis, performance and assessment of fragments released during use.

Robert Landsiedel, Wendel Wohlleben, W. Wohlleben, 2013, Nanoscale.

Organ burden of inhaled nanoceria in a 2-year low-dose exposure study: dump or depot?

Peter Laux, Andreas Luch, Robert Landsiedel, 2020, Nanotoxicology.

No genotoxicity in rat blood cells upon 3- or 6-month inhalation exposure to CeO2 or BaSO4 nanomaterials

Markus Schulz, Robert Landsiedel, Lan Ma-Hock, 2017, Mutagenesis.

Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance.

Andrew Worth, Robert Landsiedel, Julien Burton, 2013, Regulatory toxicology and pharmacology : RTP.

Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements

Robert Landsiedel, David Basketter, D. Basketter, 2012, Journal of applied toxicology : JAT.

Safety assessment of nanomaterials using an advanced decision-making framework, the DF4nanoGrouping

Robert Landsiedel, Wendel Wohlleben, Ursula G. Sauer, 2017, Journal of Nanoparticle Research.

Concern-driven integrated approaches for the grouping, testing and assessment of nanomaterials.

Robert Landsiedel, R. Landsiedel, 2016, Environmental pollution.

The Bovine Corneal Opacity and Permeability Test in Routine Ocular Irritation Testing and its Improvement within the Limits of OECD Test Guideline 437

Hans Raabe, Robert Landsiedel, Bennard van Ravenzwaay, 2011, Alternatives to laboratory animals : ATLA.

Putting the parts together: combining in vitro methods to test for skin sensitizing potentials.

Robert Landsiedel, Annette Mehling, Bennard van Ravenzwaay, 2012, Regulatory toxicology and pharmacology : RTP.

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte‐based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I)

Jean Krutmann, Robert Landsiedel, Ellen Fritsche, 2012, Experimental dermatology.

Assessing skin sensitization hazard in mice and men using non-animal test methods.

Petra S Kern, Robert Landsiedel, Annette Mehling, 2015, Regulatory toxicology and pharmacology : RTP.

Testing Metal‐Oxide Nanomaterials for Human Safety

Alexandra Kroll, Jürgen Schnekenburger, Robert Landsiedel, 2010 .

Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation.

Robert Landsiedel, Wendel Wohlleben, Ursula G Sauer, 2014, Toxicology and applied pharmacology.

Concern-Driven Safety Assessment of Nanomaterials: An Integrated Approach Using Material Properties, Hazard, Biokinetic, and Exposure Data and Considerations on Grouping and Read-Across

Robert Landsiedel, Peter M.J. Bos, Agnes Oomen, 2014 .

Acute and chronic effects of nano- and non-nano-scale TiO(2) and ZnO particles on mobility and reproduction of the freshwater invertebrate Daphnia magna.

Robert Landsiedel, Sabine Zok, Wendel Wohlleben, 2009, Chemosphere.

Genotoxicity of nanomaterials: Refining strategies and tests for hazard identification

Robert Landsiedel, Masamitsu Honma, Shareen H Doak, 2013, Environmental and molecular mutagenesis.

Linking energy metabolism to dysfunctions in mitochondrial respiration--a metabolomics in vitro approach.

Robert Landsiedel, S N Kolle, H. Kamp, 2011, Toxicology letters.

Influence of dispersive agent on nanomaterial agglomeration and implications for biological effects in vivo or in vitro.

Robert Landsiedel, Wendel Wohlleben, Ursula G Sauer, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

LuSens: a keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification.

Robert Landsiedel, Annette Mehling, Ben van Ravenzwaay, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

Alternatives for skin sensitisation: Hazard identification and potency categorisation: Report from an EPAA/CEFIC LRI/Cosmetics Europe cross sector workshop, ECHA Helsinki, April 23rd and 24th 2015.

Andrew Worth, Silvia Casati, Robert Landsiedel, 2015, Regulatory toxicology and pharmacology : RTP.

Experience with local lymph node assay performance standards using standard radioactivity and non-radioactive cell count measurements

Robert Landsiedel, Susanne N. Kolle, David A. Basketter, 2011 .

Testing Metal‐Oxide Nanomaterials for Human Safety

Alexandra Kroll, Jürgen Schnekenburger, Robert Landsiedel, 2010, Advanced materials.

Toxico-/biokinetics of nanomaterials

Robert Landsiedel, Franz Oesch, Wendel Wohlleben, 2012, Archives of Toxicology.

Acute Oral Toxicity Testing: Scientific Evidence and Practicability Should Govern Three Rs Activities

Robert Landsiedel, Roland Buesen, Ursula G Sauer, 2016, Alternatives to laboratory animals : ATLA.

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

Robert Landsiedel, Antje Vennemann, Ursula G. Sauer, 2016, Journal of Nanobiotechnology.

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping).

Reinhard Kreiling, Robert Landsiedel, Wendel Wohlleben, 2015, Regulatory toxicology and pharmacology : RTP.

Non-animal test methods for predicting skin sensitization potentials

Robert Landsiedel, Bennard van Ravenzwaay, Annette Mehling, 2012, Archives of Toxicology.

Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies.

Robert Landsiedel, Annette Mehling, Bennard van Ravenzwaay, 2012, Regulatory toxicology and pharmacology : RTP.

Effects of SiO2, ZrO2, and BaSO4 nanomaterials with or without surface functionalization upon 28-day oral exposure to rats

Robert Landsiedel, Roland Buesen, Hennicke Kamp, 2014, Archives of Toxicology.

Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance.

Robert Landsiedel, Bennard van Ravenzwaay, Karin Wiench, 2009, Inhalation toxicology.

The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies.

Monika Herrchen, Dana Kühnel, Michael Stintz, 2019, Nanoscale.

Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.

Robert Landsiedel, Bennard van Ravenzwaay, Susanne N Kolle, 2011, Regulatory toxicology and pharmacology : RTP.

Abiotic dissolution rates of 24 (nano)forms of 6 substances compared to macrophage-assisted dissolution and in vivo pulmonary clearance: Grouping by biodissolution and transformation

Robert Landsiedel, Antje Vennemann, Wendel Wohlleben, 2018, NanoImpact.

In-house Validation of the EpiOcular™ Eye Irritation Test and its Combination with the Bovine Corneal Opacity and Permeability Test for the Assessment of Ocular Irritation

Robert Landsiedel, Susanne N. Kolle, Helena Kandárová, 2011, Alternatives to laboratory animals : ATLA.

Experience with the HET-CAM Method in the Routine Testing of a Broad Variety of Chemicals and Formulations

Robert Landsiedel, Ben van Ravenzwaay, B. van Ravenzwaay, 2010 .

Local Tolerance Testing under REACH: Accepted Non-animal Methods are Not on Equal Footing with Animal Tests

Robert Landsiedel, Annette Mehling, Susanne N. Kolle, 2016, Alternatives to laboratory animals : ATLA.

Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice.

Reinhard Kreiling, Robert Landsiedel, Wendel Wohlleben, 2016, Regulatory toxicology and pharmacology : RTP.

In Vitro and In Vivo Short-Term Pulmonary Toxicity of Differently Sized Colloidal Amorphous SiO2

Robert Landsiedel, Antje Vennemann, Wendel Wohlleben, 2018, Nanomaterials.

Comparing fate and effects of three particles of different surface properties: nano-TiO(2), pigmentary TiO(2) and quartz.

Robert Landsiedel, Ben van Ravenzwaay, Lan Ma-Hock, 2009, Toxicology letters.

Experience with local lymph node assay performance standards using standard radioactivity and nonradioactive cell count measurements

Robert Landsiedel, David Basketter, D. Basketter, 2012, Journal of applied toxicology : JAT.

Refinement and Reduction of Acute Oral Toxicity Testing: A Critical Review of the Use of Cytotoxicity Data

Markus Schulz, Robert Landsiedel, Bennard van Ravenzwaay, 2011, Alternatives to laboratory animals : ATLA.

Nanosafety in Europe 2015-2025: Towards Safe and Sustainable Nanomaterials and Nanotechnology Innovations. Finnish Institute of Occupational Health

Bengt Fadeel, Teresa F. Fernandes, D. Brouwer, 2013 .

Feasibility Assessment of Micro-Electrode Chip Assay as a Method of Detecting Neurotoxicity in vitro

Antonio Novellino, Robert Landsiedel, Maurice Whelan, 2011, Front. Neuroeng..

Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies

Robert Landsiedel, Christoph L. Klein, Karin Wiench, 2012, Archives of Toxicology.

Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.

Robert Landsiedel, Bennard van Ravenzwaay, Susanne N Kolle, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Regulatory accepted but out of domain: In vitro skin irritation tests for agrochemical formulations

Robert Landsiedel, Bennard van Ravenzwaay, Susanne N Kolle, 2017, Regulatory toxicology and pharmacology : RTP.

Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency.

Emanuela Corsini, Janine Ezendam, Robert Landsiedel, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

A short-term inhalation study protocol: designed for testing of toxicity and fate of nanomaterials.

Robert Landsiedel, Thomas Hofmann, Bennard van Ravenzwaay, 2014, Methods in molecular biology.

Drug-Metabolizing Enzymes in the Skin of Man, Rat, and Pig

Robert Landsiedel, Franz Oesch, F. Oesch, 2007, Drug metabolism reviews.

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

Hugh J. Byrne, Antonio Marcomini, Peter Wick, 2013, Nanotoxicology.

t 4 Workshop Report * State-ofthe-Art of 3 D Cultures ( Organs-ona-Chip ) in Safety Testing and Pathophysiology

Mardas Daneshian, Thomas Hartung, Robert Landsiedel, 2014 .

A multi‐laboratory evaluation of microelectrode array‐based measurements of neural network activity for acute neurotoxicity testing

Sergio Martinoia, Michela Chiappalone, Antonio Novellino, 2017, Neurotoxicology.

Intra- and inter-laboratory reproducibility and accuracy of the LuSens assay: A reporter gene-cell line to detect keratinocyte activation by skin sensitizers.

Sebastian Hoffmann, Robert Landsiedel, Annette Mehling, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Nanosafety in Europe 2015-2020: Towards Safe and Sustainable Nanomaterials and Nanotechnology Innovations

Bengt Fadeel, D. Brouwer, Robert Landsiedel, 2013 .

Environmental Risk Assessment Strategy for Nanomaterials

Antonio Marcomini, Lang Tran, Bernd Nowack, 2017, International journal of environmental research and public health.

Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?

Qasim Chaudhry, Robert Landsiedel, Helinor Johnston, 2017, Regulatory toxicology and pharmacology : RTP.

Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies.

Jürgen Schnekenburger, Robert Landsiedel, Ursula G Sauer, 2014, Nanomedicine.

Assessment of the oxidative potential of nanoparticles by the cytochrome c assay: assay improvement and development of a high-throughput method to predict the toxicity of nanoparticles

Robert Landsiedel, Wendel Wohlleben, Sonja Boland, 2016, Archives of Toxicology.

In vivo-in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems.

Robert Landsiedel, Bennard van Ravenzwaay, Lan Ma-Hock, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Lacking applicability of in vitro eye irritation methods to identify seriously eye irritating agrochemical formulations: Results of bovine cornea opacity and permeability assay, isolated chicken eye test and the EpiOcular™ ET‐50 method to classify according to UN GHS

Robert Landsiedel, Susanne N. Kolle, Bennard van Ravenzwaay, 2017, Regulatory toxicology and pharmacology : RTP.