M. Covarrubias

发表

Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate

L. Salkoff, M. Covarrubias, A. Wei, 1994, Neuron.

The Neuronal Kv4 Channel Complex

M. Covarrubias, Aditya Bhattacharji, J. A. Santiago-Castillo, 2008, Neurochemical Research.

Molecular physiology and modulation of somatodendritic A-type potassium channels

M. Covarrubias, H. Jerng, P. Pfaffinger, 2004, Molecular and Cellular Neuroscience.

K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

L. Salkoff, M. Covarrubias, A. Wei, 1990, Science.

An essential ‘set’ of K+ channels conserved in flies, mice and humans

Lawrence Salkoff, Aguan Wei, L. Salkoff, 1992, Trends in Neurosciences.

Novel Activation of Voltage-gated K+ Channels by Sevoflurane*

Annika F. Barber, M. Covarrubias, Qiansheng Liang, 2012, The Journal of Biological Chemistry.

Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels

M. Covarrubias, Manuel Covarrubias, Jeffrey D. Fineberg, 2012, The Journal of general physiology.

Kv3.4 channel function and dysfunction in nociceptors

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2015, Channels.

Dysregulation of Kv3.4 Channels in Dorsal Root Ganglia Following Spinal Cord Injury

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2015, The Journal of Neuroscience.

A Dipeptidyl Aminopeptidase–like Protein Remodels Gating Charge Dynamics in Kv4.2 Channels

M. Covarrubias, Kevin Dougherty, 2006, The Journal of general physiology.

Excision of membrane patches reduces the mean open time of nicotinic acetylcholine receptors

J. Steinbach, M. Covarrubias, 1990, Pflügers Archiv.

Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes and prolongs cardiac action potential duration

W. Koch, M. Covarrubias, C. Peers, 2018, The Journal of Biological Chemistry.

A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of γ-Aminobutyric Acid, Type A (GABAA), Receptor Subunit Binding Selectivity in Synaptosomes*

B. Garcia, R. Eckenhoff, J. Hénin, 2016, The Journal of Biological Chemistry.

Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation.

B. Garcia, R. Eckenhoff, M. Covarrubias, 2017, ACS chemical biology.

CALCIUM‐DEPENDENT BINDING OF BRAIN GLUTAMATE DECARBOXYLASE TO PHOSPHOLIPID VESICLES

M. Covarrubias, R. Tapia, 1978, Journal of neurochemistry.

Glutamate Decarboxylase, Properties and the Synaptic Function of GABA

M. Covarrubias, R. Tapia, 1978 .

Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

M. Covarrubias, A. Fernández-Cid, L. Delemotte, 2021, Nature Communications.

Electrophysiological Analysis of Voltage-Gated Ion Channel Modulation by General Anesthetics.

M. Covarrubias, Lianteng Zhi, Qiansheng Liang, 2018, Methods in enzymology.

Closed-state inactivation involving an internal gate in Kv4.1 channels modulates pore blockade by intracellular quaternary ammonium ions

M. Covarrubias, G. Panyi, T. Szanto, 2016, Scientific Reports.

Dipeptidyl‐peptidase‐like proteins cast in a new role: enabling scorpion toxin block of A‐type K+ channels

M. Covarrubias, 2013, The Journal of physiology.

The Dipeptidyl-Peptidase-Like Protein DPP6 Determines the Unitary Conductance of Neuronal Kv4.2 Channels

B. Rudy, M. Covarrubias, M. Nadal, 2009, The Journal of Neuroscience.

Inhalational anaesthetics and n‐alcohols share a site of action in the neuronal Shaw2 Kv channel

M. Covarrubias, Aditya Bhattacharji, R. C. V. Go, 2010, British journal of pharmacology.

Inactivation Gating of Kv4 Potassium Channels Molecular Interactions Involving the Inner Vestibule of the Pore

M. Covarrubias, H. Jerng, M. Shahidullah, 1999 .

Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels

R. Eckenhoff, M. Covarrubias, P. Loll, 2018, Molecular Neurobiology.

Novel Activation of Voltage-gated K (cid:1) Channels by Sevoflurane *

Annika F. Barber, M. Covarrubias, Qiansheng Liang, 2020 .

Shaker, Shal, Shab, and Shaw express independent K+ current systems

Lawrence Salkoff, Aguan Wei, L. Salkoff, 1991, Neuron.

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2018, Front. Mol. Neurosci..

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2018, Front. Mol. Neurosci..

Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic Action

M. Covarrubias, Caio S. Souza, W. Treptow, 2015, PloS one.

Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K+ Channel Dysfunction in DRG Neurons

M. Covarrubias, Stephen R. Tymanskyj, Benjamin M Zemel, 2017, The Journal of Neuroscience.

A mouse brain homolog of the Drosophila Shab K+ channel with conserved delayed-rectifier properties

L. Salkoff, M. Covarrubias, M. Pak, 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites

M. Klein, R. Eckenhoff, V. Carnevale, 2018, The Journal of general physiology.

Low molecular weight poly(A)+ mRNA species encode factors that modulate gating of a non-Shaker A-type K+ channel

M. Covarrubias, N. Bakry, L. D. Chabala, 1993, The Journal of general physiology.

Cortactin Is Required for N-cadherin Regulation of Kv1.5 Channel Function*

M. Covarrubias, G. Radice, Lan Cheng, 2011, The Journal of Biological Chemistry.

Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K+ Channel

M. Covarrubias, Guangyu Wang, 2006, The Journal of general physiology.

Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2005, The Journal of general physiology.

Remodelling inactivation gating of Kv4 channels by KChIP1, a small‐molecular‐weight calcium‐binding protein

K. Rhodes, M. Covarrubias, M. Bowlby, 2002, The Journal of physiology.

Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain

P. Distefano, K. Rhodes, M. Covarrubias, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Functionally Active T 1T 1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv 4 Channels

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2005 .

Zn2+-dependent Redox Switch in the Intracellular T1-T1 Interface of a Kv Channel*

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2007, Journal of Biological Chemistry.

Permeation Properties and Differential Expression across the Auditory Receptor Epithelium of an Inward Rectifier K+ Channel Cloned from the Chick Inner Ear (*)

M. Covarrubias, J. Oberholtzer, D. Navaratnam, 1995, The Journal of Biological Chemistry.

A high-affinity, partial antagonist effect of 3,4-diaminopyridine mediates action potential broadening and enhancement of transmitter release at NMJs

Evan W. Miller, M. Covarrubias, S. D. Meriney, 2021, The Journal of biological chemistry.

Ethanol selectively blocks a noninactivating K+ current expressed in Xenopus oocytes.

M. Covarrubias, E. Rubin, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Interactions between Multiple Phosphorylation Sites in the Inactivation Particle of a K+ Channel

M. Covarrubias, S. Slater, R. Sorensen, 1998, The Journal of general physiology.

Potent inhibition of the aortic smooth muscle maxi-K channel by clinical doses of ethanol.

M. Covarrubias, J. S. Ellingson, F. S. Walters, 2000, American journal of physiology. Cell physiology.

The Concerted Contribution of the S4-S5 Linker and the S6 Segment to the Modulation of a Kv Channel by 1-Alkanols

M. Covarrubias, Aditya Bhattacharji, M. Germann, 2006, Molecular Pharmacology.

Alcohols Inhibit a Cloned Potassium Channel at a Discrete Saturable Site

M. Covarrubias, A. Wei, T. Vyas, 1995, The Journal of Biological Chemistry.

NMR Analysis of KChIP4a Reveals Structural Basis for Control of Surface Expression of Kv4 Channel Complexes*

B. Fakler, M. Covarrubias, H. Kalbacher, 2008, Journal of Biological Chemistry.

PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity‐dependent manner

M. Covarrubias, Lianteng Zhi, Stephen R. Tymanskyj, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role for the propofol hydroxyl in anesthetic protein target molecular recognition.

R. Eckenhoff, M. Covarrubias, Brian P. Weiser, 2015, ACS chemical neuroscience.

Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate

H. Kalbitzer, J. Ruppersberg, B. Fakler, 1999, Nature Structural Biology.

Inhibitors of asparagine-linked oligosaccharide processing alter the kinetics of the nicotinic acetylcholine receptor

J. Steinbach, M. Covarrubias, C. Kopta, 1989, The Journal of general physiology.

Mechanisms of closed‐state inactivation in voltage‐gated ion channels

M. Covarrubias, R. Bähring, 2011, The Journal of physiology.

A procedure for detecting changes in the internal ca2+ concentration in isolated nerve endings using the metallochromic dye arsenazo III

M. Covarrubias, R. Tapia, 1982, Neuroscience.

The dipeptidyl-aminopeptidase-like protein 6 is an integral voltage sensor-interacting β-subunit of neuronal KV4.2 channels

M. Covarrubias, Kevin Dougherty, C. Deutsch, 2009, Channels.

Ternary Kv4.2 channels recapitulate voltage‐dependent inactivation kinetics of A‐type K+ channels in cerebellar granule neurons

B. Rudy, M. Covarrubias, Y. Amarillo, 2008, The Journal of physiology.

Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation

M. Covarrubias, Kevin Dougherty, J. A. De Santiago-Castillo, 2008, The Journal of general physiology.

Mechanism of the modulation of Kv4:KChIP-1 channels by external K+.

M. Covarrubias, Y. Kaulin, J. A. De Santiago-Castillo, 2008, Biophysical journal.

The link between ion permeation and inactivation gating of Kv4 potassium channels.

M. Covarrubias, M. Shahidullah, 2003, Biophysical journal.

Kv4 channels exhibit modulation of closed-state inactivation in inside-out patches.

M. Covarrubias, E. Beck, Edward J. Beck, 2001, Biophysical journal.

Dysregulation of Kv 3 . 4 channels in dorsal root ganglia following spinal cord injury

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2017 .

Regulation of Nociceptive Glutamatergic Signaling by Presynaptic Kv3.4 Channels in the Rat Spinal Dorsal Horn

M. Covarrubias, B. Ghosh, A. Lepore, 2018, The Journal of Neuroscience.

Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation

R. Eckenhoff, V. Carnevale, M. Covarrubias, 2018, The Journal of general physiology.

The Dipeptidyl-peptidase-like-protein DPP6 Determines the Unitary Conductance of Neuronal Kv4.2 Channels

B. Rudy, M. Covarrubias, M. Nadal, 2009 .

A novel N-terminal motif of dipeptidyl peptidase-like proteins inactivates KV4.2 channels by a pore-blocking mechanism

M. Covarrubias, Kevin Dougherty, H. Jerng, 2009, Channels.

Ligand‐specific state transitions of the membrane‐bound acetylcholine receptor

A. Maelicke, M. Covarrubias, H. Prinz, 1984, FEBS letters.

Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors

R. Eckenhoff, K. Miller, M. Covarrubias, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mechanistic Insights into the Modulation of Voltage-Gated Ion Channels by Inhalational Anesthetics.

Annika F. Barber, R. Eckenhoff, V. Carnevale, 2015, Biophysical journal.

Modulation of a voltage-gated Na+ channel by sevoflurane involves multiple sites and distinct mechanisms

Annika F. Barber, M. Klein, R. Eckenhoff, 2014, Proceedings of the National Academy of Sciences.

Molecular mapping of general anesthetic sites in a voltage-gated ion channel.

Annika F. Barber, M. Covarrubias, W. Treptow, 2011, Biophysical journal.

Function of Mammalian Nicotinic Acetylcholine Receptors

J. Steinbach, S. Sine, M. Covarrubias, 1986 .

Alcohol and anesthetic action at the gate of a voltage-dependent K+ channel

M. Covarrubias, Aditya Bhattacharji, M. Germann, 2005 .

General Anesthetic Action at an Internal Protein Site Involving the S4-S5 Cytoplasmic Loop of a Neuronal K+Channel*

M. Covarrubias, M. Shahidullah, J. S. Ellingson, 2000, The Journal of Biological Chemistry.

Azi-isoflurane, a Photolabel Analog of the Commonly Used Inhaled General Anesthetic Isoflurane

R. Eckenhoff, M. Shimaoka, M. Covarrubias, 2009, ACS chemical neuroscience.

Insight into the modulation of Shaw2 Kv channels by general anesthetics: structural and functional studies of S4-S5 linker and S6 C-terminal peptides in micelles by NMR.

M. Covarrubias, M. Germann, Xiaoguang Qu, 2013, Biochimica et biophysica acta.

mShal, a subfamily of A-type K+ channel cloned from mammalian brain.

L. Salkoff, M. Covarrubias, A. Butler, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Kv4 Channels Underlie the Subthreshold-Operating A-type K+-current in Nociceptive Dorsal Root Ganglion Neurons

M. Covarrubias, Thanawath Ratanadilok Na Phuket, 2009, Front. Mol. Neurosci..

Modulation of Kv3.4 channel N‐type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons

M. Covarrubias, Cojen Ho, D. Ritter, 2012, The Journal of physiology.

Inactivation Gating of Kv4 Potassium Channels

M. Covarrubias, H. Jerng, M. Shahidullah, 1999, The Journal of general physiology.

Binding Sites and the Mechanism of Action of Propofol and a Photoreactive Analogue in Prokaryotic Voltage-Gated Sodium Channels.

R. Eckenhoff, V. Carnevale, M. Covarrubias, 2021, ACS chemical neuroscience.

Dysregulation of Kv3.4 Channels in Dorsal Root Ganglia Following Spinal Cord Injury

M. Covarrubias, D. Ritter, Benjamin M Zemel, 2015, The Journal of Neuroscience.

K+ channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains.

M. Covarrubias, H. Jerng, M Covarrubias, 1997, Biophysical journal.

Cumulative Activation of Voltage-Dependent KVS-1 Potassium Channels

L. Salkoff, M. Covarrubias, P. Rojas, 2008, The Journal of Neuroscience.

Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate.

M. Covarrubias, T. Harris, Andrew R Graber, 2003, American journal of physiology. Cell physiology.