A. Arason

发表

High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.

D. Easton, Å. Borg, O. Johannsson, 1996, Cancer research.

Identification of the breast cancer susceptibility gene BRCA2

D. Bentley, A. Ashworth, S. Seal, 1995, Nature.

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.

J Chang-Claude, M. Stratton, J. Chang-Claude, 1998, American journal of human genetics.

High Prevalence of the 999 del 5 Mutation in Icelandic Breast and Ovarian Cancer Patients 1

D. Easton, Å. Borg, J. Gudmundsson, 2006 .

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus.

E. Gillanders, D. Stephan, H. Grönberg, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Jane E. Carpenter, Jaana M. Hartikainen, W. Chung, 2019, Nature Genetics.

High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

M. Ringnér, P. Malmström, Å. Borg, 2010, Breast Cancer Research.

Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

M. Ringnér, Å. Borg, N. Loman, 2010, Breast Cancer Research.

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Christiana Kartsonaki, Mads Thomassen, Julian Peto, 2010, Nature Genetics.

High expression of the vacuole membrane protein 1 (VMP1) is a potential marker of poor prognosis in HER2 positive breast cancer

O. Johannsson, B. Agnarsson, R. Barkardottir, 2019, PloS one.

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Jack A. Taylor, W. Chung, S. Cross, 2019, bioRxiv.

Replication error in human breast cancer: comparison with clinical variables and family history of cancer.

G. Eiriksdottir, A. Arason, S. Ingvarsson, 1999, Oncology reports.

Frequent Occurrence of BRCA 2 Linkage in Icelandic Breast Cancer Families and Segregation of a Common BRCA 2 Haplotype

J. Gudmundsson, J. Bergthórsson, R. Barkardottir, 2007 .

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

Annette Lee, W. Chung, R. Nussbaum, 2018, Human mutation.

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3

W. Chung, R. Nussbaum, F. Couch, 2016, Breast Cancer Research and Treatment.

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

D. Altshuler, P. Fasching, P. Hall, 2013, PLoS genetics.

The BRCA1 c.4096+3A>G Variant Displays Classical Characteristics of Pathogenic BRCA1 Mutations in Hereditary Breast and Ovarian Cancers, But Still Allows Homozygous Viability

B. Agnarsson, R. Barkardottir, I. Reynisdottir, 2019, Genes.

Identification of a novel splice‐site mutation of the BRCA1 gene in two breast cancer families: Screening reveals low frequency in Icelandic breast cancer patients

A. Jonasdottir, Å. Borg, J. Bergthórsson, 1998, Human mutation.

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

M. Daly, D. Altshuler, F. Couch, 2010, PLoS Genetics.

Male breast cancer in BRCA1 and BRCA2 mutation carriers

R. Nussbaum, D. Steinemann, F. Couch, 2018 .

Polymorphism of the c‐Ha‐ras‐1 proto‐oncogene in sporadic and familial breast cancer

V. Gudnason, R. Barkardottir, O. Johannsson, 1989, International journal of cancer.

Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations.

J. Gudmundsson, R. Barkardottir, G. Eiriksdottir, 1995, British Journal of Cancer.

Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.

J. Gudmundsson, R. Barkardottir, G. Johannesdottir, 1995, Cancer research.

The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients

B. Agnarsson, R. Barkardottir, I. Reynisdottir, 2012, BMC Cancer.

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Päivi Heikkilä, Mads Thomassen, Stephen Fox, 2011, Cancer Epidemiology, Biomarkers & Prevention.

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

Stefania Tommasi, Laura Cortesi, Mads Thomassen, 2019, Cancer research.

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

R. Nussbaum, D. Steinemann, F. Couch, 2016, Breast Cancer Research.

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

R. Nussbaum, D. Steinemann, V. Pankratz, 2014, Breast Cancer Research.

Transcriptome ‐ wide association study of breast cancer risk by estrogen ‐ receptor status

Jack A. Taylor, W. Chung, S. Cross, 2020 .

High allele loss rates at I7q I2‐q2I in breast and ovarian tumors from BRCAI‐linked families

J. Chang-Claude, B. Ponder, C. Larsson, 1995 .

A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland.

A. Jonasdottir, D. Easton, J. Bergthórsson, 1998, Journal of medical genetics.

Identification of subtypes in human epidermal growth factor receptor 2--positive breast cancer reveals a gene signature prognostic of outcome.

Johan Staaf, Mårten Fernö, Markus Ringnér, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Jane E. Carpenter, Jack A. Taylor, W. Chung, 2019, Nature Genetics.

Haplotype analysis in Icelandic and Finnish BRCA2 999del5 breast cancer families

J. Kere, O. Kallioniemi, R. Barkardottir, 2001, European Journal of Human Genetics.

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

M. Daly, D. Altshuler, F. Couch, 2010, PLoS genetics.

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.

F. Couch, O. Olopade, T. Rebbeck, 2007, American journal of human genetics.

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Mads Thomassen, Nina Ditsch, Muhammad Usman Rashid, 2015, JAMA.

Molecular and Cellular Pathobiology The Retinoblastoma Gene Undergoes Rearrangements in BRCA 1-De fi cient Basal-like Breast Cancer

M. Ringnér, L. Saal, M. Fernö, 2012 .

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Jane E. Carpenter, Jack A. Taylor, W. Chung, 2019, Nature Communications.

Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors

Å. Borg, B. Agnarsson, R. Barkardottir, 2006, International journal of cancer.

High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer

M. Ringnér, Å. Borg, O. Johannsson, 2013, Cancer medicine.

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies

J. Kere, L. Aaltonen, P. Møller, 2006, Journal of Medical Genetics.

The effect of a single BRCA2 mutation on cancer in Iceland

R. Barkardottir, J. Eyfjord, A. Arason, 2002, Journal of medical genetics.

Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways

B. Agnarsson, R. Barkardottir, I. Reynisdottir, 2021, PloS one.

Molecular and Cellular Pathobiology The Retinoblastoma Gene Undergoes Rearrangements in BRCA 1-De fi cient Basal-like Breast Cancer

L. Saal, Å. Borg, N. Loman, 2012 .

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

F. Couch, O. Olopade, J. Benítez, 2021, Journal of the National Cancer Institute.

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

D. Steinemann, F. Couch, O. Olopade, 2017, Journal of Clinical Oncology.

A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes

Heli Nevanlinna, Therese Sandberg, Dietrich A. Stephan, 2002, Human Genetics.

Chromosome imbalance at the 3p14 region in human breast tumours: high frequency in patients with inherited predisposition due to BRCA2.

A. Jonasdottir, R. Barkardottir, G. Eiriksdottir, 1998, European journal of cancer.

Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours

M. Ringnér, Å. Borg, R. Barkardottir, 2012, Breast Cancer Research and Treatment.

Pathology of Breast andOvarian Cancers among BRCA 1 and BRCA 2 Mutation Carriers : Results from the Consortium of Investigators of Modi fi ers of BRCA 1 / 2 ( CIMBA )

R. Nussbaum, V. Pankratz, F. Couch, 2011 .

Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

W. Chung, V. Pankratz, F. Couch, 2012, Cancer Epidemiology, Biomarkers & Prevention.

The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

W. Chung, F. Couch, O. Olopade, 2021, Genetics in Medicine.

Oestrogen receptor status, treatment and breast cancer prognosis in Icelandic BRCA2 mutation carriers

O. Johannsson, B. Agnarsson, R. Barkardottir, 2016, British Journal of Cancer.

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

Jane E. Carpenter, A. Whittemore, S. Cross, 2016, Breast Cancer Research.

Syddansk Universitet Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12 p 11 locus

Jane E. Carpenter, S. Cross, P. Fasching, 2016 .

Title Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA 1 and BRCA 2 mutation carriers

R. Nussbaum, D. Steinemann, V. Pankratz, 2015 .

Chromosome 17q-linkage seems to be infrequent in Icelandic families at risk of breast cancer.

A. Jonasdottir, J. Gudmundsson, R. Barkardottir, 1995, Acta oncologica.

Linkage analysis and allelic imbalance in human breast cancer kindreds using microsatellite markers from the short arm of chromosome 3

J. Bergthórsson, R. Barkardottir, G. Eiriksdottir, 1995, Human Genetics.

Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype.

J. Gudmundsson, R. Barkardottir, G. Johannesdottir, 1996, American journal of human genetics.

Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer.

R. Barkardottir, A. Arason, V. Egilsson, 1993, American journal of human genetics.

Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables.

Å. Borg, H. Olsson, B. Agnarsson, 2004, Anticancer research.

Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families

E. Gillanders, P. Møller, Å. Borg, 2010, Breast Cancer Research.

Evidence against PALB2 involvement in Icelandic breast cancer susceptibility

E. Gillanders, B. Agnarsson, R. Barkardottir, 2008, Journal of Negative Results in Biomedicine.

Candidate Genetic Modifiers for Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

W. Chung, R. Nussbaum, D. Steinemann, 2014, Cancer Epidemiology, Biomarkers & Prevention.

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers

R. Barkardottir, J. Bergthorsson, A. Arason, 2001, Breast Cancer Research.

Analysis of HPC1, HPCX, and PCaP in Icelandic hereditary prostate cancer

E. Gillanders, J. Trent, J. Bergthórsson, 2000, Human Genetics.

High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.

B. Ponder, P. Tonin, D. Kelsell, 1995, Genes, chromosomes & cancer.

Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non‐polyposis colon cancer trait

J. Gudmundsson, J. Bergthórsson, A. Arason, 1995, Clinical genetics.

Mutation analysis of the CHK 2 gene in breast carcinoma and other cancers

R. Barkardottir, J. Bergthorsson, A. Arason, 2002 .

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

A. Whittemore, B. Karlan, E. John, 2023, British Journal of Cancer.

The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers

F. Couch, D. Easton, K. Offit, 2012, Breast Cancer Research and Treatment.

The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714predict adverse outcome for breast cancer patients

B. Agnarsson, R. Barkardottir, I. Reynisdottir, 2012, BMC Cancer.

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

Joshua M. Korn, Debra, M. Daly, 2010, PLoS genetics.

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

Jane E. Carpenter, A. Whittemore, S. Cross, 2016, Breast Cancer Research.

High Atlastin 2-2 (ATL2-2) Expression Associates with Worse Prognosis in Estrogen-Receptor-Positive Breast Cancer

B. Agnarsson, R. Barkardottir, I. Reynisdottir, 2023, Genes.

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

V. Pankratz, F. Couch, T. Rebbeck, 2012, Breast Cancer Research and Treatment.

University of Groningen Identification of a BRCA 2-Specific Modifier Locus at 6 p 24 Related to Breast Cancer

D. Altshuler, V. Pankratz, F. Couch, 2017 .

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

A. Whittemore, F. Couch, B. Bonanni, 2015 .

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers

R. Barkardottir, J. Bergthorsson, A. Arason, 2002, Breast Cancer Research.