C. Humpel

C. Humpel, M. Pirchl, 2009, Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater.

Intranasal neprilysin rapidly eliminates amyloid-beta plaques, but causes plaque compensations: the explanation why the amyloid-beta cascade may fail?

C. Humpel, 2022, Neural regeneration research.

Platelet and Plasma Phosphatidylcholines as Biomarkers to Diagnose Cerebral Amyloid Angiopathy

C. Humpel, J. Marksteiner, H. Oberacher, 2020, Frontiers in Neurology.

Saliva tau and phospho-tau-181 measured by Lumipulse in patients with Alzheimer’s disease

C. Humpel, J. Marksteiner, M. Defrancesco, 2022, Frontiers in Aging Neuroscience.

Preparation of organotypic brain slice cultures for the study of Alzheimer’s disease

C. Humpel, W. Noble, S. Barnett, 2018, F1000Research.

Effects of Ischemia on the Migratory Capacity of Microglia Along Collagen Microcontact Prints on Organotypic Mouse Cortex Brain Slices

C. Humpel, Katharina Steiner, 2022, Frontiers in Cellular Neuroscience.

Effect of noradrenergic denervation by neonatal DSP-4 on peptide neurotransmitter systems in the rat brain

C. Humpel, A. Saria, J. Donnerer, 1992, Neuropeptides.

Neuropeptide Levels after Pentylenetetrazol Kindling in the Rat

G. Sperk, H. Lassmann, C. Humpel, 1990, The European journal of neuroscience.

Catestatin-like immunoreactivity in the rat eye

F. Grus, C. Humpel, K. Lorenz, 2014, Neuropeptides.

Serpinin in the Skin

M. Nolano, V. Provitera, C. Humpel, 2022, Biomedicines.

Clusters of Cortical Spreading Depolarizations in a Patient with Intracerebral Hemorrhage: A Multimodal Neuromonitoring Study

C. Humpel, R. Helbok, I. Unterberger, 2015, Neurocritical Care.

Brain capillary endothelial cells proliferate in response to NGF, express NGF receptors and secrete NGF after inflammation

C. Humpel, I. Blasig, M. Reindl, 2004, Brain Research.

Protein Kinase C and Phosphoinositol-3-Kinase Mediate Differentiation or Proliferation of Slice-Derived Rat Microglia

C. Humpel, B. Zassler, Christine Schermer, 2003, Pharmacology.

Effects of oxidative stress on amyloid precursor protein processing in rat and human platelets

C. Humpel, T. Hochstrasser, D. Ehrlich, 2013, Platelets.

Chronic treatment with five vascular risk factors causes cerebral amyloid angiopathy but no Alzheimer pathology in C57BL6 mice

C. Humpel, Bettina M. Foidl, 2019, Brain, Behavior, and Immunity.

Urea enhances the nerve growth factor-induced neuroprotective effect on cholinergic neurons in organotypic rat brain slices

C. Humpel, G. Dechant, B. Zassler, 2005, Neuroscience.

Organotypic Brain Slices of ADULT Transgenic Mice: A Tool to Study Alzheimer's Disease.

C. Humpel, 2019, Current Alzheimer research.

Down-regulation of complement receptor 3 and major histocompatibility complex I and II antigen-like immunoreactivity accompanies ramification in isolated rat microglia

C. Humpel, K. Salimi, 2002, Brain Research.

Pronounced increases in brain levels of calcitonin gene-related peptide after kainic acid induced seizures

G. Sperk, C. Humpel, J. Marksteiner, 1989, Regulatory Peptides.

VIP, PACAP‐38, BDNF and ADNP in NMDA‐induced excitotoxicity in the rat retina

C. Humpel, J. Waschek, E. Schmid, 2009, Acta ophthalmologica.

Effects of ethanol on aggregation, serotonin release, and amyloid precursor protein processing in rat and human platelets

C. Humpel, D. Ehrlich, 2014, Platelets.

Elevated levels of substance P in intraocular fluid in proliferative vitreoretinopathy

C. Humpel, A. Saria, C. Kunze, 1991, Peptides.

Antidepressants and Anti-Inflammatory Drugs Differentially Reduce the Release of NGF and BDNF from Rat Platelets

C. Humpel, B. Sperner-Unterweger, T. Hochstrasser, 2012, Pharmacopsychiatry.

Neurokinin a is a main constituent of sensory neurons innervating the anterior segment of the eye.

A. Laslop, C. Humpel, Johannes Leierer, 2005, Investigative ophthalmology & visual science.

Brain Extracellular Interleukin-6 Levels Decrease Following Antipyretic Therapy with Diclofenac in Patients with Spontaneous Subarachnoid Hemorrhage.

C. Humpel, W. Hackl, R. Helbok, 2019, Therapeutic hypothermia and temperature management.

Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b+ microglial-like cell type in vitro

C. Humpel, Bianca Hutter-Schmid, 2018, Experimental Gerontology.

Cell death of adult pyramidal CA1 neurons after intraventricular injection of a novel peptide derived from trkA

C. Humpel, T. Ebendal, R. Schneider, 1997, Journal of neuroscience research.

Cerebrovascular damage as a cause for Alzheimer's disease.

C. Humpel, J. Marksteiner, 2005, Current neurovascular research.

Circulating nerve growth factor in primary and secondary Raynaud's syndrome - results of a pilot study.

C. Humpel, G. Riemekasten, P. Klein-Weigel, 2009, VASA. Zeitschrift fur Gefasskrankheiten.

Differential Changes in Tachykinins in the Rat Brain after Drug‐induced Seizures a

G. Sperk, C. Humpel, J. Marksteiner, 1991, Annals of the New York Academy of Sciences.

Differential changes in tachykinins after kainic acid-induced seizures in the rat

G. Sperk, C. Humpel, J. Marksteiner, 1990, Neuroscience.

Differential changes in mRNAs encoding for preprotachykinin A and B after kainic acid‐induced seizures in the rat

G. Sperk, C. Humpel, J. Marksteiner, 1991, Synapse.

Organotypic Brain Slice Cultures

C. Humpel, 2018, Current protocols in immunology.

Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses

Nina Daschil, C. Humpel, 2014, Brain Research.

Organotypic vibrosections: Novel whole sagittal brain cultures

Nina Daschil, C. Humpel, C. Ullrich, 2011, Journal of Neuroscience Methods.

Margatoxin and iberiotoxin, two selective potassium channel inhibitors, induce c-fos like protein and mRNA in rat organotypic dorsal striatal slices

C. Humpel, A. Saria, H. S. Fischer, 2000, Amino Acids.

Influence of patient-related variables on clozapine plasma levels.

W. Fleischhacker, C. Humpel, A. Saria, 1990, The American journal of psychiatry.

MDMA (‘ecstasy’) enhances basal acetylcholine release in brain slices of the rat striatum

C. Humpel, A. Saria, G. Zernig, 2000, The European journal of neuroscience.

The Organic Cation Transporter 2 Inhibitor Quinidine Modulates the Neuroprotective Effect of Nerve Growth Factor and Memantine on Cholinergic Neurons of the Basal Nucleus of Meynert in Organotypic Brain Slices

C. Humpel, S. Sahin, T. Gulsun, 2021, Pharmacology.

Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas.

C. Humpel, W. Philipp, L. Speicher, 2000, Investigative ophthalmology & visual science.

Retinoic acid treatment enhances the acetylcholine contents in the human teratocarcinoma cell line NTera-2

C. Humpel, A. Saria, I. Berti, 2000, Regulatory Peptides.

Chronic Infusion of Nerve Growth Factor into Rat Striatum Increases Cholinergic Markers and Inhibits Striatal Neuronal Discharge Rate

I. Strömberg, C. Humpel, P. Förander, 1996, The European journal of neuroscience.

Increase of basic fibroblast growth factor (bFGF, FGF-2) messenger RNA and protein following implantation of a microdialysis probe into rat hippocampus

K. Fuxe, D. Ganten, L. Olson, 2004, Experimental Brain Research.

Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models

I. Strömberg, Nina Daschil, C. Humpel, 2014, Molecular and Cellular Neuroscience.

Therapeutic efficacy of glial cell-derived neurotrophic factor loaded collagen scaffolds in ex vivo organotypic brain slice Parkinson’s disease models

C. Humpel, Buket Ucar, 2019, Brain Research Bulletin.

Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits

C. Humpel, C. Ullrich, M. Pirchl, 2010, Molecular and Cellular Neuroscience.

Short- and Long-Term Treatment of Mouse Cortical Primary Astrocytes with β-Amyloid Differentially Regulates the mRNA Expression of L-Type Calcium Channels

Nina Daschil, C. Humpel, G. Obermair, 2014, Pharmacology.

Organotypic brain slice cultures as a model to study angiogenesis of brain vessels

C. Humpel, Kathrin M. Kniewallner, Bianca Hutter-Schmid, 2015, Front. Cell Dev. Biol..

L-type calcium channel CaV 1.2 in transgenic mice overexpressing human AbetaPP751 with the London (V717I) and Swedish (K670M/N671L) mutations.

F. Hofmann, C. Humpel, J. Marksteiner, 2010, Journal of Alzheimer's disease : JAD.

Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells

C. Humpel, M. Sortino, S. Merlo, 2023, Biomolecules.

Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert

C. Humpel, C. Weis, J. Marksteiner, 2001, Neuroscience.

Sphingomyelin SM(d18:1/18:0) is significantly enhanced in cerebrospinal fluid samples dichotomized by pathological amyloid-β42, tau, and phospho-tau-181 levels.

G. Kemmler, C. Humpel, T. Koal, 2015, Journal of Alzheimer's disease : JAD.

Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo

L. Olson, I. Strömberg, B. Hoffer, 1993, Experimental Neurology.

Telomere length is age-dependent and reduced in monocytes of Alzheimer patients

C. Humpel, J. Marksteiner, T. Hochstrasser, 2012, Experimental Gerontology.

Alpha-Smooth Muscle Actin mRNA and Protein Are Increased in Isolated Brain Vessel Extracts of Alzheimer Mice

C. Humpel, Bianca Hutter-Schmid, 2016, Pharmacology.

Intravenous Infusion of Monocytes Isolated from 2-Week-Old Mice Enhances Clearance of Beta-Amyloid Plaques in an Alzheimer Mouse Model

C. Humpel, Lindsay A. Hohsfield, 2015, PloS one.

Migration of blood cells to β-amyloid plaques in Alzheimer’s disease

C. Humpel, Lindsay A. Hohsfield, 2015, Experimental Gerontology.

The ratio of phosphatidylcholines to lysophosphatidylcholines in plasma differentiates healthy controls from patients with Alzheimer's disease and mild cognitive impairment

G. Kemmler, C. Humpel, J. Marksteiner, 2015, Alzheimer's & dementia.

Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease

G. Kemmler, C. Humpel, J. Marksteiner, 2017, Metabolomics.

Platelets in the Alzheimer's Disease Brain: do they Play a Role in Cerebral Amyloid Angiopathy?

C. Humpel, J. Marksteiner, D. Ehrlich, 2015, Current neurovascular research.

Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice

P. Gressens, C. Humpel, G. Simbruner, 2008, Neurobiology of Disease.

Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?

Christian Humpel, C. Humpel, 2011, Experimental Gerontology.

Growth factors and cytokines/chemokines as surrogate biomarkers in cerebrospinal fluid and blood for diagnosing Alzheimer’s disease and mild cognitive impairment

L. Olson, C. Humpel, 2010, Experimental Gerontology.

Cholinergic neurons degenerate when exposed to conditioned medium of primary rat brain capillary endothelial cells: Counteraction by NGF, MK-801 and inflammation

C. Humpel, Petra Stöckl, K. Moser, 2006, Experimental Gerontology.

Cerebrospinal Fluid Levels of 14-3-3 Gamma: What Does It Tell Us About Sporadic Creutzfeldt-Jakob Disease?

C. Humpel, T. Benke, 2017, Pharmacology.

Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices

C. Humpel, M. Pirchl, D. Ehrlich, 2012, Brain Research.

Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats

C. Humpel, M. Pirchl, D. Ehrlich, 2012, Neuroscience.

Regulation of brain-derived neurotrophic factor messenger RNA and protein at the cellular level in pentylenetetrazol-induced epileptic seizures

L. Olson, C. Humpel, L. Olson, 1993, Neuroscience.

Effects of GABA and l-glutamic acid on the potassium-evoked in vitro release of substance P- and neurokinin A-like immunoreactivities are different in the rat striatum and substantia nigra

C. Humpel, A. Saria, 1989, Neuroscience Letters.

Collagen hydrogels loaded with fibroblast growth factor-2 as a bridge to repair brain vessels in organotypic brain slices

C. Humpel, Buket Ucar, Sedef Yusufogullari, 2020, Experimental Brain Research.

CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-β plaques in an Alzheimer's disease mouse model.

Nina Daschil, C. Humpel, G. Obermair, 2013, Journal of Alzheimer's disease : JAD.

Platelet dysfunction in hypercholesterolemia mice, two Alzheimer’s disease mouse models and in human patients with Alzheimer’s disease

C. Humpel, J. Marksteiner, B. Plagg, 2015, Biogerontology.

Intranasal Delivery of Collagen-Loaded Neprilysin Clears Beta-Amyloid Plaques in a Transgenic Alzheimer Mouse Model

C. Humpel, 2021, Frontiers in Aging Neuroscience.

Platelet-derived secreted amyloid-precursor protein-β as a marker for diagnosing Alzheimer's disease.

C. Humpel, J. Marksteiner, 2013, Current neurovascular research.

Matrix metalloproteinase-2 and epidermal growth factor are decreased in platelets of Alzheimer patients.

C. Humpel, J. Marksteiner, B. Sperner-Unterweger, 2012, Current Alzheimer research.

Spreading of Beta-Amyloid in Organotypic Mouse Brain Slices and Microglial Elimination and Effects on Cholinergic Neurons

C. Humpel, Kurt Moelgg, Faryal Jummun, 2021, Biomolecules.

Platelets: Their Potential Contribution to the Generation of Beta-amyloid Plaques in Alzheimer's Disease.

C. Humpel, 2017, Current neurovascular research.

Thiazine Red+ platelet inclusions in Cerebral Blood Vessels are first signs in an Alzheimer’s Disease mouse model

C. Humpel, D. Wenzel, Kathrin M. Kniewallner, 2016, Scientific Reports.

Green-Fluorescent Protein+ Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis

Nina Daschil, C. Humpel, 2016, Front. Aging Neurosci..

Platelets in Alzheimer’s Disease

C. Humpel, B. Plagg, 2015 .

Acyl-Alkyl-Phosphatidlycholines are Decreased in Saliva of Patients with Alzheimer's Disease as Identified by Targeted Metabolomics.

C. Humpel, J. Marksteiner, H. Oberacher, 2019, Journal of Alzheimer's disease : JAD.

Platelets isolated from an Alzheimer mouse damage healthy cortical vessels and cause inflammation in an organotypic ex vivo brain slice model

C. Humpel, Bettina M. Foidl, Kathrin M. Kniewallner, 2018, Scientific Reports.

Targeted Metabolomic Analysis of Soluble Lysates from Platelets of Patients with Mild Cognitive Impairment and Alzheimer's Disease Compared to Healthy Controls: Is PC aeC40:4 a Promising Diagnostic Tool?

C. Humpel, C. Linhart, J. Marksteiner, 2017, Journal of Alzheimer's disease : JAD.

Differential changes in platelet reactivity induced by acute physical compared to persistent mental stress

C. Humpel, P. Malik, J. Giesinger, 2015, Physiology & Behavior.

Cerebrospinal fluid and blood biomarkers in Alzheimer's disease.

C. Humpel, T. Hochstrasser, 2011, World journal of psychiatry.

Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid

C. Humpel, Bettina M. Foidl, 2018, Front. Aging Neurosci..

Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood–brain barrier leakage in rats in vivo

Christian Humpel, C. Humpel, Daniela Ehrlich, 2012, Journal of the Neurological Sciences.

Effects of acidosis on brain capillary endothelial cells and cholinergic neurons: relevance to vascular dementia and Alzheimer's disease

C. Humpel, J. Marksteiner, M. Pirchl, 2006, Neurological research.

L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model

Nina Daschil, C. Humpel, G. Obermair, 2015, Neurobiology of Aging.

Analysis of 27 vascular-related proteins reveals that NT-proBNP is a potential biomarker for Alzheimer's disease and mild cognitive impairment: A pilot-study

G. Kemmler, C. Humpel, J. Marksteiner, 2014, Experimental Gerontology.

Brain capillaries and cholinergic neurons persist in organotypic brain slices in the absence of blood flow

R. Schmidt-Kastner, H. Hinterhuber, C. Humpel, 2003, The European journal of neuroscience.

Beta-amyloid expression, release and extracellular deposition in aged rat brain slices

C. Humpel, J. Marksteiner, Josef Marksteiner, 2008, Molecular Psychiatry.

Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light

G. Kemmler, C. Humpel, M. Pirchl, 2010 .

Plasma phosphatidylcholines and vitamin B12/folate levels are possible prognostic biomarkers for progression of Alzheimer's disease

G. Kemmler, C. Humpel, J. Marksteiner, 2021, Experimental Gerontology.

Chromogranin B and Secretogranin II in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations and in Alzheimer patients.

C. Humpel, J. Marksteiner, S. Mahata, 2008, Journal of Alzheimer's disease : JAD.

Chromogranin peptides in Alzheimer's disease

Christian Humpel, K. Jellinger, C. Humpel, 2004, Experimental Gerontology.

W. Fleischhacker, H. Hinterhuber, C. Humpel, 2004, Psychopharmacology.

The Alzheimer’s Association external quality control program for cerebrospinal fluid biomarkers

Giovanni B. Frisoni, José Luis Molinuevo, Aase Handberg, 2011, Alzheimer's & Dementia.

Synaptic proteins in Alzheimer’s disease

C. Humpel, J. Marksteiner, W. Kaufmann, 2002, Journal of Molecular Neuroscience.

Serum Tau as a predictor for neurological outcome after cardiopulmonary resuscitation.

H. Ulmer, C. Humpel, R. Helbok, 2020, Resuscitation.

Differential effects of phencyclidine application on secretogranin II expression in organotypic slices of rat prefrontal cortex

W. Fleischhacker, C. Humpel, J. Marksteiner, 2003, Journal of neurochemistry.

First localization and biochemical identification of chromogranin B- and secretoneurin-like immunoreactivity in the fetal human vagal/nucleus solitary complex

C. Humpel, J. Marksteiner, M. Bitsche, 2006, Regulatory Peptides.

Microcontact Printing of Cholinergic Neurons in Organotypic Brain Slices

C. Humpel, K. Steiner, 2021, Frontiers in Neurology.

Synaptic loss reflected by secretoneurin‐like immunoreactivity in the human hippocampus in Alzheimer's disease

H. Hinterhuber, C. Humpel, J. Marksteiner, 1998, The European journal of neuroscience.

Mesencephalic grafts increase preprotachykinin-A mRNA expression in striatal grafts in an in oculo co-graft model

I. Strömberg, C. Humpel, J. Marksteiner, 1995, Regulatory Peptides.

Stress Enhances Proinflammatory Platelet Activity: the Impact of Acute and Chronic Mental Stress

C. Humpel, J. Giesinger, B. Sperner-Unterweger, 2020, Journal of Neuroimmune Pharmacology.

β‐Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti‐inflammatory drugs

C. Humpel, B. Sperner-Unterweger, T. Hochstrasser, 2012, Journal of neuroscience research.

Early brain injury after aneurysmal subarachnoid hemorrhage: a multimodal neuromonitoring study

Christian Humpel, C. Humpel, W. Hackl, 2015, Critical Care.

Rotenone Induces Cell Death of Cholinergic Neurons in an Organotypic Co-Culture Brain Slice Model

C. Humpel, C. Ullrich, 2009, Neurochemical Research.

Cerebrospinal beta-amyloid peptides(1-40) and (1-42) in severe preeclampsia and HELLP syndrome – a pilot study

C. Humpel, W. Lederer, G. Putz, 2020, Scientific Reports.

Cerebrospinal fluid levels of tau and phospho-tau-181 proteins during pregnancy.

C. Humpel, W. Lederer, M. Popovscaia, 2016, Pregnancy hypertension.

Platelet-derived Growth Factor Receptor-beta is Differentially Regulated in Primary Mouse Pericytes and Brain Slices.

C. Humpel, Bianca Hutter-Schmid, 2016, Current neurovascular research.

Inflammatory status of transmigrating primary rat monocytes in a novel perfusion model simulating blood flow

C. Humpel, C. Ammann, Lindsay A. Hohsfield, 2013, Journal of Neuroimmunology.

Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1.

C. Humpel, Lindsay A. Hohsfield, 2010, Current neurovascular research.

Differential effects of short‐ and long‐term hyperhomocysteinaemia on cholinergic neurons, spatial memory and microbleedings in vivo in rats

C. Humpel, C. Ullrich, M. Pirchl, 2010, The European journal of neuroscience.

Rapid and sensitive determination of clozapine in human plasma using high-performance liquid chromatography and amperometric detection.

C. Humpel, A. Saria, C. Haring, 1989, Journal of chromatography.

W. Fleischhacker, C. Humpel, A. Saria, 1989, Journal of clinical psychopharmacology.

Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system

L. Olson, I. Strömberg, B. Hoffer, 1996, Cell and Tissue Research.

Platelet TAU is Associated with Changes in Depression and Alzheimer's Disease.

B. Sarg, C. Humpel, J. Marksteiner, 2022, Frontiers in Bioscience.

Clozapine plasma levels determined by high-performance liquid chromatography with ultraviolet detection.

W. Fleischhacker, H. Hinterhuber, C. Humpel, 1988, Journal of chromatography.

Expression of BDNF and trkB mRNAs in comparison to dopamine D1 and D2 receptor mRNAs and tyrosine hydroxylase-immunoreactivity in nigrostriatal in oculo co-grafts.

I. Strömberg, C. Humpel, 1995, Brain research. Developmental brain research.

Receptors for NGF and GDNF are highly expressed in human peripheral nerve neuroma

C. Humpel, C. Harpf, J. Dabernig, 2002, Muscle & nerve.

Spreading of Aggregated α-Synuclein in Sagittal Organotypic Mouse Brain Slices

C. Humpel, N. Stefanova, Buket Ucar, 2022, Biomolecules.

Co-distribution patterns of chromogranin B-like immunoreactivity with chromogranin A and secretoneurin within the human brainstem

C. Humpel, J. Marksteiner, A. Schrott-Fischer, 2000, Brain Research.

Fast and widespread increase of basic fibroblast growth factor messenger RNA and protein in the forebrain after kainate-induced seizures

K. Fuxe, D. Ganten, C. Humpel, 1993, Neuroscience.

Measurement of Thirteen Biological Markers in CSF of Patients with Alzheimer’s Disease and Other Dementias

H. Hinterhuber, G. Kemmler, C. Humpel, 2005, Dementia and Geriatric Cognitive Disorders.

W. Fleischhacker, H. Hinterhuber, C. Humpel, 1989 .

Peripheral Biomarkers in Dementia and Alzheimer's Disease

C. Humpel, J. Marksteiner, 2009 .

Bioprofiling of platelets in medicated patients with depression.

C. Humpel, P. Malik, J. Giesinger, 2015, Journal of affective disorders.

Two Blood Monocytic Biomarkers (CCL15 and p21) Combined with the Mini-Mental State Examination Discriminate Alzheimer's Disease Patients from Healthy Subjects

G. Kemmler, C. Humpel, J. Marksteiner, 2011, Dementia and Geriatric Cognitive Disorders Extra.

Failure of Neuroprotection by Embryonic Striatal Grafts in a Double Lesion Rat Model of Striatonigral Degeneration (Multiple System Atrophy)

M. Levivier, C. Scherfler, W. Poewe, 2000, Experimental Neurology.

Analysis of Cerebrospinal Fluid of Alzheimer Patients

H. Hinterhuber, C. Humpel, J. Marksteiner, 2008, Pharmacology.

Matrix metalloproteinases-2 and -3 are reduced in cerebrospinal fluid with low beta-amyloid1–42 levels

C. Humpel, R. Mlekusch, Reinhilde Mlekusch, 2009, Neuroscience Letters.

Evidence that toxicity of lipopolysaccharide upon cholinergic basal forebrain neurons requires the presence of glial cells in vitro

C. Humpel, C. Weis, 2002, Brain Research Bulletin.

Tumor necrosis factor-alpha triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons.

C. Humpel, C. Weis, B. Zassler, 2003, Brain research. Molecular brain research.

5-HT3 receptor antagonists inhibit sensory neuropeptide release from the rat spinal cord.

C. Humpel, A. Saria, R. Gamse, 1990, Neuroreport.

Dkk‐3 is elevated in CSF and plasma of Alzheimer’s disease patients

C. Humpel, J. Marksteiner, P. Berger, 2009, Journal of neurochemistry.

Brain microdialysate tau dynamics predict functional and neurocognitive recovery after poor-grade subarachnoid haemorrhage

C. Scherfler, A. Djamshidian, L. Zamarian, 2023, Brain communications.

Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release After Spontaneous Subarachnoid Hemorrhage.

C. Humpel, R. Helbok, R. Beer, 2017, Current drug targets.

Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome

Margarete Delazer, Thomas Benke, Christian Humpel, 2014, Journal of Neurology, Neurosurgery & Psychiatry.

Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro

C. Humpel, J. Marksteiner, A. Saria, 1996, Cell and Tissue Research.

Platelets isolated from an Alzheimer mouse damage healthy cortical vessels and cause inflammation in an organotypic ex vivo brain slice model

C. Humpel, Bettina M. Foidl, Kathrin M. Kniewallner, 2018, Scientific Reports.

Melatonin Supports the Survival of Cholinergic Neurons in Organotypic Brain Slices of the Basal Nucleus of Meynert

C. Humpel, Grazia Ilaria Caruso, Dhwani S Korde, 2023, Pharmacology.

Total Tau-Protein as Investigated by Cerebral Microdialysis Increases in Hypothermic Cardiac Arrest: A Pig Study.

P. Mair, C. Humpel, R. Helbok, 2020, Therapeutic hypothermia and temperature management.

Detection of nerve growth factor mRNA in rodent salivary glands with digoxigenin- and 33P-labeled oligonucleotides: effects of castration and sympathectomy.

L. Olson, C. Humpel, E. Lindqvist, 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Dopamine neurons in a simple GDNF-treated meso-striatal organotypic co-culture model

C. Humpel, W. Kaufmann, A. Saria, 1999, Experimental Brain Research.

Transplantation of NGF secreting primary monocytes counteracts NMDA-induced cell death of rat cholinergic neurons in vivo

C. Humpel, B. Zassler, 2006, Experimental Neurology.

Saliva: a challenging human fluid to diagnose brain disorders with a focus on Alzheimer’s disease

C. Humpel, Christine Zürcher, 2023, Neural regeneration research.

Salivary Flow and Composition

C. Humpel, Christine Zürcher, 2023 .

Ubiquitin enzymes, ubiquitin and proteasome activity in blood mononuclear cells of MCI, Alzheimer and Parkinson patients.

C. Humpel, J. Marksteiner, C. Ullrich, 2010, Current Alzheimer research.

Injection of tachykinins and selective neurokinin receptor ligands into the substantia nigra reticulata increases striatal dopamine and 5-hydroxytryptamine metabolism.

C. Humpel, A. Saria, D. Regoli, 1991, European journal of pharmacology.

Magnetic stimulation induces neuronal c-fos via tetrodotoxin-sensitive sodium channels in organotypic cortex brain slices of the rat

H. Hinterhuber, C. Humpel, A. Hausmann, 2001, Neuroscience Letters.

Distribution of chromogranin B-like immunoreactivity in the human hippocampus and its changes in Alzheimer’s disease

K. Jellinger, C. Humpel, J. Marksteiner, 2000, Acta Neuropathologica.

Primary rat monocytes migrate through a BCEC-monolayer and express microglia-markers at the basolateral side

C. Humpel, K. Moser, 2007, Brain Research Bulletin.

Mini-Ruby is Rapidly Taken up by Neurons and Astrocytes in Organotypic Brain Slices

C. Humpel, C. Ullrich, 2011, Neurochemical Research.

Blood-Derived Serum Albumin Contributes to Neurodegeneration via Astroglial Stress Fiber Formation

C. Humpel, K. Moser, 2007, Pharmacology.

Editorial: Platelets as Players in Neuropathologies: Novel Diagnostic and Therapeutic Targets

C. Humpel, J. Orian, S. Wassmer, 2021, Frontiers in Immunology.

Acetylcholine, Drug Reward and Substance Use Disorder Treatment: Intra- and Interindividual Striatal and Accumbal Neuron Ensemble Heterogeneity May Explain Apparent Discrepant Findings

C. Humpel, G. Zernig, G. Dechant, 2012, Pharmacology.

Chronic repetitive transcranial magnetic stimulation (rTMS) does not affect tyrosine hydroxylase (TH) and dopamine‐β‐hydroxylase (DBH) expression in rats in vivo

H. Hinterhuber, C. Humpel, A. Hausmann, 2002, Synapse.

Compartmentation of alpha 1 and alpha 2 GABAA receptor subunits within rat extended amygdala: implications for benzodiazepine action

G. Alheid, C. Humpel, J. Marksteiner, 2003, Brain Research.

Galanin and galanin receptors in human gliomas

C. Humpel, M. Huemer, A. Berger, 2003, Acta Neuropathologica.

Lipid-Mediated In Vivo Gene Transfer Replaces the Loss of Choline Acetyltransferase Activity after Unilateral Fimbria-Fornix Aspiration

C. Humpel, C. Weis, W. Kaufmann, 2001, Cell transplantation.

Glial Cells: Astrocytes and Oligodendrocytes during Normal Brain Aging

C. Humpel, I. Blasko, B. Grubeck‐Loebenstein, 2009 .

Soluble cell adhesion molecules in monocytes of Alzheimer’s disease and mild cognitive impairment

C. Humpel, E. Weiss, J. Marksteiner, 2010, Experimental Gerontology.

Monocytes deliver bioactive nerve growth factor through a brain capillary endothelial cell-monolayer in vitro and counteract degeneration of cholinergic neurons

C. Humpel, C. Ullrich, Danny Böttger, 2010, Brain Research.

Galactose Counteracts Hypoglycemia-Induced Decline of Cholinergic Neurons at Low pH in Organotypic Rat Brain Slices of the Basal Nucleus of Meynert

C. Humpel, M. Pirchl, 2011, Pharmacology.

L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model

Nina Daschil, C. Humpel, G. Obermair, 2015, Neurobiology of Aging.

Pentylenetetrazol kindling decreases N-methyl-d-aspartate and kainate but increases gamma-aminobutyric acid-A receptor binding in discrete rat brain areas

C. Humpel, J. Luthman, 1997, Neuroscience Letters.

Analysis of Cerebrospinal Fluid of Alzheimer Patients

H. Hinterhuber, C. Humpel, J. Marksteiner, 2008, Pharmacology.

Endogenous 5‐Hydroxytryptamine Modulates the Release of Tachykinins and Calcitonin Gene—related Peptide from the Rat Spinal Cord via 5‐HT3 Receptors

C. Humpel, A. Saria, R. Gamse, 1991, Annals of the New York Academy of Sciences.