C. Knauf

发表

Apelin, a promising target for type 2 diabetes treatment?

I. Castan-Laurell, C. Dray, C. Knauf, 2012, Trends in Endocrinology & Metabolism.

Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin.

B. Viollet, F. Tronche, C. Knauf, 2006, Endocrinology.

Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

J. Ferrières, J. Tanti, C. Knauf, 2007, Diabetes.

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

R. Bibiloni, C. Knauf, Patrice D Cani, 2008, Diabetes.

Glucosensing in the gastrointestinal tract: Impact on glucose metabolism.

Carla Cirillo, C. Knauf, Patrice D Cani, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.

G. Rutter, G. Kelsey, W. Dean, 2004, The Journal of clinical investigation.

Altered Gut Microbiota and Endocannabinoid System Tone in Obese and Diabetic Leptin-Resistant Mice: Impact on Apelin Regulation in Adipose Tissue

P. François, J. Schrenzel, W. D. de Vos, 2011, Front. Microbio..

Maternal hypertension induced by NO blockade does not program adult metabolic diseases in growth-restricted rat fetuses.

S. Mayeur, J. Lesage, L. Storme, 2013, Metabolism: Clinical and Experimental.

Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes

C. Knauf, M. Iglesias, G. Gibson, 2007 .

Improvement of Glucose Tolerance and Hepatic Insulin Sensitivity by Oligofructose Requires a Functional Glucagon-Like Peptide 1 Receptor

D. Drucker, C. Knauf, Patrice D Cani, 2006, Diabetes.

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917

C. Knauf, É. Oswald, J. Galano, 2017, Nature Communications.

Camu-Camu Reduces Obesity and Improves Diabetic Profiles of Obese and Diabetic Mice: A Dose-Ranging Study

C. Knauf, Patrice D Cani, N. Delzenne, 2022, Metabolites.

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis

Andreas Zimmer, Sophie Lotersztajn, Alexandre Louvet, 2009, PloS one.

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.

C. Kahn, D. Drucker, J. Tanti, 2005, The Journal of clinical investigation.

Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure.

C. Dray, C. Knauf, P. Valet, 2008, Endocrinology.

Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice

J. Lesage, C. Knauf, P. Valet, 2016, Scientific Reports.

Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.

C. Knauf, P. Valet, C. Perrin, 2007, Endocrinology.

Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety

B. Katzenellenbogen, J. Foidart, J. Katzenellenbogen, 2018, Journal of the American Heart Association.

Inflammation and Gut-Brain Axis During Type 2 Diabetes: Focus on the Crosstalk Between Intestinal Immune Cells and Enteric Nervous System

C. Knauf, Patrice D Cani, E. Meunier, 2018, Front. Neurosci..

Elabela and Apelin actions in healthy and pathological pregnancies.

J. Lesage, C. Knauf, C. Breton, 2019, Cytokine & growth factor reviews.

GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion

J. Holst, D. Drucker, C. Knauf, 2007, Molecular and Cellular Endocrinology.

Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing

R. Seeley, D. Drucker, C. Knauf, 2008, Diabetes.

Glucagon-like peptide-1 and energy homeostasis.

C. Knauf, Patrice D Cani, R. Burcelin, 2007, The Journal of nutrition.

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

J. Tanti, C. Knauf, M. Iglesias, 2007, Diabetologia.

Central Insulin Regulates Heart Rate and Arterial Blood Flow

C. Sartori, C. Knauf, Patrice D Cani, 2007, Diabetes.

Hypothalamic Actions of Apelin on Energy Metabolism: New Insight on Glucose Homeostasis and Metabolic Disorders

C. Knauf, P. Valet, A. Fournel, 2013, Hormone and Metabolic Research.

Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.

W. Wahli, S. Kersten, C. Knauf, 2006, Endocrinology.

Targeting the Enteric Nervous System to Treat Metabolic Disorders? “Enterosynes” as Therapeutic Gut Factors

C. Knauf, Patrice D Cani, A. Abot, 2019, Neuroendocrinology.

Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis.

C. Knauf, C. Perrin, R. Burcelin, 2004, Endocrinology.

Glucagon-Like Peptide-1 and Energy Homeostasis 1 – 3

C. Knauf, Patrice D Cani, R. Burcelin, 2007 .

Pharmacological inhibition of the F1‐ATPase/P2Y1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation

C. Knauf, Marcelo González, C. Aguayo, 2019, Acta physiologica.

Peroxisome Proliferator-Activated Receptor-- Null Mice Have Increased White Adipose Tissue Glucose Utilization , GLUT 4 , and Fat Mass : Role in Liver and Brain

W. Wahli, S. Kersten, C. Knauf, 2006 .

Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice

C. Knauf, D. Withers, Patrice D Cani, 2006, Diabetologia.

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

T. Horvath, C. Knauf, A. Zorzano, 2017, Cell metabolism.

A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion.

C. Knauf, Patrice D Cani, 2021, Cell metabolism.

Critical role of PCYT2 in muscle health and aging

G. Superti-Furga, J. Penninger, C. Knauf, 2022, bioRxiv.

5/6 nephrectomy affects enteric glial cells and promotes impaired antioxidant defense in the colonic neuromuscular layer.

C. Knauf, D. C. Magliano, Ágatha Cristie Menezes, 2022, Life sciences.

Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.

N. Chassaing, J. Schanstra, M. Pontoglio, 2017, Journal of the American Society of Nephrology : JASN.

Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis

J. Penninger, C. Knauf, T. Gustafsson, 2021, bioRxiv.

How does apelin affect LH levels? An investigation at the level of GnRH and KNDy neurons

P. Froment, C. Knauf, A. Abot, 2022, Molecular and Cellular Endocrinology.

Endothelin-1 Exhibiting Pro-Nociceptive and Pro-Peristaltic Activities Is Increased in Peritoneal Carcinomatosis

C. Knauf, L. Basso, A. Fournel, 2021, Frontiers in Pain Research.

Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing

C. Knauf, A. Galinier, C. Magnan, 2018, Molecular metabolism.

In Vivo Assessment of Antioxidant Potential of Human Milk Treated by Holder Pasteurization or High Hydrostatic Pressure Processing: A Preliminary Study on Intestinal and Hepatic Markers in Adult Mice

J. Lesage, C. Knauf, L. Carneiro, 2022, Antioxidants.

Prenatal fasudil exposure alleviates fetal growth but programs hyperphagia and overweight in the adult male rat.

I. Fajardy, S. Mayeur, J. Lesage, 2012, European journal of pharmacology.

Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice

J. Lesage, C. Knauf, Patrice D Cani, 2020, Gut.

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia

C. Knauf, Patrice D Cani, R. Burcelin, 2007, Diabetologia.

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

B. Katzenellenbogen, J. Foidart, J. Katzenellenbogen, 2014, EMBO molecular medicine.

Bisphenol S exposure affects gene expression related to intestinal glucose absorption and glucose metabolism in mice

C. Knauf, A. Abot, R. Rezg, 2018, Environmental Science and Pollution Research.

Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics.

C. Knauf, Patrice D Cani, A. Neyrinck, 2014, Beneficial microbes.

Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate

Karin Aumayr, O. Wagner, G. Dietzl, 2010, Cell.

Influence of acute and chronic administration of benzylamine on glucose tolerance in diabetic and obese mice fed on very high-fat diet

F. Milagro, C. Knauf, R. Burcelin, 2007, Journal of Physiology and Biochemistry.

Impact of Intestinal Peptides on the Enteric Nervous System: Novel Approaches to Control Glucose Metabolism and Food Intake

C. Knauf, Patrice D Cani, A. Abot, 2018, Front. Endocrinol..

Relation between colonic proglucagon expression and metabolic response to oligofructose in high fat diet-fed mice.

C. Knauf, Patrice D Cani, R. Burcelin, 2006, Life sciences.

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis

C. Knauf, É. Oswald, Patrice D Cani, 2020, Gut.

Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders

C. Knauf, Patrice D Cani, Claude Knauf, 2018, Obesity.

Apelin, diabetes, and obesity

I. Castan-Laurell, C. Dray, C. Knauf, 2011, Endocrine.

Reactive Oxygen Species / Reactive Nitrogen Species as Messengers in the Gut: Impact on Physiology and Metabolic Disorders.

C. Knauf, Patrice D Cani, A. Abot, 2021, Antioxidants & redox signaling.

Impact of hypothalamic reactive oxygen species in the regulation of energy metabolism and food intake

C. Knauf, P. Valet, A. Fournel, 2015, Front. Neurosci..

Gut microbiome, endocrine control of gut barrier function and metabolic diseases.

C. Knauf, Patrice D Cani, M. Van Hul, 2020, The Journal of endocrinology.

The gut microbiome influences host endocrine functions.

C. Knauf, Patrice D Cani, Marialetizia Rastelli, 2019, Endocrine reviews.

Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat

M. Febbraio, J. Penninger, C. Knauf, 2012, Cell.

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice.

I. Castan-Laurell, C. Dray, C. Knauf, 2008, Cell metabolism.

Apelin receptors: From signaling to antidiabetic strategy.

I. Castan-Laurell, C. Dray, C. Knauf, 2015, European journal of pharmacology.

Apelin targets gut contraction to control glucose metabolism via the brain

C. Knauf, P. Valet, Patrice D Cani, 2015, Gut.

Apelin and the proopiomelanocortin system: a new regulatory pathway of hypothalamic α-MSH release.

C. Knauf, P. Valet, L. Jeandel, 2011, American journal of physiology. Endocrinology and metabolism.

Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes.

J. Lesage, D. Vieau, C. Knauf, 2014, Antioxidants & redox signaling.

The apelinergic system: Sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice

J. Lesage, L. Storme, C. Knauf, 2013, Peptides.

Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes

P. Bénit, C. Kahn, I. Ebersberger, 2007, Cell.

Critical role of PCYT2 in muscle health and aging

G. Superti-Furga, J. Penninger, C. Knauf, 2023, bioRxiv.

Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

Julian J. Emmanuel, A. Ashworth, Mark A. Smith, 2011, Diabetes.

Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism

J. Tanti, C. Knauf, Patrice D Cani, 2017, Molecular systems biology.

Variation of Endothelial Nitric Oxide Synthase Synthesis in the Median Eminence during the Rat Estrous Cycle: An Additional Argument for the Implication of Vascular Blood Vessel in the Control of GnRH Release.

C. Knauf, V. Prévot, J. Beauvillain, 2001, Endocrinology.

How gut microbes talk to organs: The role of endocrine and nervous routes

C. Knauf, Patrice D Cani, 2016, Molecular metabolism.

Glucose Stimulates Gut Motility in Fasted and Fed Conditions: Potential Involvement of a Nitric Oxide Pathway

J. Lesage, C. Knauf, Patrice D Cani, 2022, Nutrients.

p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice.

Céline Guilbeau-Frugier, Philippe Valet, C. Knauf, 2013, Antioxidants & redox signaling.

Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

V. Routh, C. Knauf, P. Valet, 2009, Diabetes.

Interactions between the microbiota and enteric nervous system during gut-brain disorders

C. Knauf, Patrice D Cani, Eve Wemelle, 2021, Neuropharmacology.

Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity

C. Knauf, P. Valet, J. Roncalli, 2015, Scientific Reports.

Galanin enhances systemic glucose metabolism through enteric Nitric Oxide Synthase-expressed neurons

C. Knauf, P. Valet, Patrice D Cani, 2018, Molecular metabolism.

Apelin Controls Fetal and Neonatal Glucose Homeostasis and Is Altered by Maternal Undernutrition

S. Mayeur, J. Lesage, D. Vieau, 2015, Diabetes.

Involvement of NPY Y2 receptor subtype in the control of the spontaneous NO/GnRH release at the rat median eminence

C. Knauf, Myriam Mariot Tran Van Chuoï, Jean-Luc Jirou-Najou, 2001, Neuroreport.

Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat

S. Mayeur, J. Lesage, D. Vieau, 2012, Peptides.

Maternal obesity alters the apelinergic system at the feto-maternal interface.

J. Lesage, L. Storme, C. Knauf, 2016, Placenta.

Evidence for a Spontaneous Nitric Oxide Release from the Rat Median Eminence: Influence on Gonadotropin-Releasing Hormone Release.

C. Knauf, V. Prévot, J. Beauvillain, 2001, Endocrinology.

Variation of endothelial nitric oxide synthase synthesis in the median eminence during the rat estrous cycle: an additional argument for the implication of vascular blood vessel in the control of GnRH release.

C. Knauf, V. Prévot, J. Beauvillain, 2001, Endocrinology.

Pancreatic alpha-cell dysfunction in diabetes.

C. Knauf, Patrice D Cani, R. Burcelin, 2008, Diabetes & metabolism.

PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

G. Superti-Furga, J. Penninger, C. Knauf, 2023, Nature Metabolism.

Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice.

I. Leclercq, I. Castan-Laurell, C. Knauf, 2011, Antioxidants & redox signaling.

Prebiotics and Modulation of Gastrointestinal Peptides

C. Knauf, Patrice D Cani, R. Burcelin, 2008 .

Central Effects of Beta-Blockers May Be Due to Nitric Oxide and Hydrogen Peroxide Release Independently of Their Ability to Cross the Blood-Brain Barrier

C. Knauf, A. Abot, A. Delarue, 2019, Front. Neurosci..

Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring

J. Lesage, D. Vieau, C. Knauf, 2017, Journal of Developmental Origins of Health and Disease.

[The APJ receptor: a new therapeutic approach in diabetic treatment].

I. Castan-Laurell, C. Dray, C. Knauf, 2015, Medecine sciences : M/S.

Effects of Bisphenol S on hypothalamic neuropeptides regulating feeding behavior and apelin/APJ system in mice.

Samir Aydi, C. Knauf, A. Abot, 2018, Ecotoxicology and environmental safety.

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917

C. Knauf, É. Oswald, J. Galano, 2017, Nature Communications.

Apelin Metabolic Functions

I. Castan-Laurell, C. Dray, C. Knauf, 2013 .

Apelin stimulates both cholecystokinin and glucagon-like peptide 1 secretions in vitro and in vivo in rodents

J. Lesage, D. Vieau, P. Dhulster, 2013, Peptides.

Food Intake Adaptation to Dietary Fat Involves PSA-Dependent Rewiring of the Arcuate Melanocortin System in Mice

C. Knauf, P. Valet, L. Pénicaud, 2012, The Journal of Neuroscience.

Pasteurized Akkermansia muciniphila improves glucose metabolism is linked with increased hypothalamic nitric oxide release

C. Knauf, Patrice D Cani, A. Abot, 2023, Heliyon.

Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus.

C. Knauf, P. Valet, D. Naslain, 2011, Antioxidants & redox signaling.

[GLP-1 and cerebral detection of glucose, a key mechanism for the regulation of glucose homeostasis].

C. Knauf, Patrice D Cani, R. Burcelin, 2006, Medecine sciences : M/S.

High Hydrostatic Pressure Processing of Human Milk Increases Apelin and GLP-1 Contents to Modulate Gut Contraction and Glucose Metabolism in Mice Compared to Holder Pasteurization

J. Lesage, C. Knauf, M. de Lamballerie, 2022, Nutrients.

Glucagon-like peptide-1 and energy homeostasis.

C. Knauf, Patrice D Cani, R. Burcelin, 2007, The Journal of nutrition.

Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus.

C. Knauf, P. Valet, D. Naslain, 2011, Antioxidants & redox signaling.

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice.

I. Castan-Laurell, C. Dray, C. Knauf, 2008, Cell metabolism.

Role of the intestinal microbiota in contributing to weight disorders and associated comorbidities

C. Knauf, A. Neyrinck, N. Delzenne, 2024, Clinical microbiology reviews.

Apelin receptors: From signaling to antidiabetic strategy.

I. Castan-Laurell, C. Dray, C. Knauf, 2015, European journal of pharmacology.