D. Malkin

C. Ackerley, A. Shlien, D. Malkin, 2010, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Issues in paediatric cancers

D. Malkin, J. Himelfarb, 2018, Cancer Prevention and Screening.

Vascular endothelial growth factor acts in an autocrine manner in rhabdomyosarcoma cell lines and can be inhibited with all-trans-retinoic acid

Claudia Eichler-Jonsson, S. Baruchel, D. Malkin, 2005, Oncogene.

Mutations in Leukemia and Myelodysplastic Syndrome after Ovarian Cancer 1

P. Hall, B. Kohler, D. Slater, 2002 .

p53 mutations in leukemia and myelodysplastic syndrome after ovarian cancer.

P. Hall, B. Kohler, D. Slater, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

“A change in perspective”: Exploring the experiences of adolescents with hereditary tumor predisposition

A. Patenaude, D. Chitayat, D. Malkin, 2018, Pediatric blood & cancer.

Absence of germline p16 INK4a alterations in p53 wild type Li-Fraumeni syndrome families

C. Portwine, F. Li, D. Malkin, 2000, Journal of medical genetics.

Genetic Basis of Hereditary Cancer Syndromes

D. Malkin, 2014 .

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies

Gretchen M. Williams, D. Malkin, K. Schneider, 2018, Clinical Cancer Research.

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies—Response

D. Malkin, A. L. Frazier, D. Orbach, 2019, Clinical Cancer Research.

Expression of p53 in renal carcinoma cells is independent of pVHL.

N. Alon, M. Ohh, D. Malkin, 2005, Mutation research.

Evidence for genetic anticipation in vonHippel-Lindau syndrome

D. Malkin, R. Kim, Bailey Gallinger, 2018, Journal of Medical Genetics.

Somatic DICER1 mutations in adult-onset pulmonary blastoma

W. Foulkes, J. Brunet, J. Bosch-Barrera, 2016, European Respiratory Journal.

Utility of a Cancer Predisposition Screening Tool for Predicting Subsequent Malignant Neoplasms in Childhood Cancer Survivors

P. Nathan, D. Johnston, W. Foulkes, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

An eHealth decision‐support tool to prioritize referral practices for genetic evaluation of patients with Wilms tumor

R. Weksberg, W. Foulkes, D. Malkin, 2020, International journal of cancer.

Proteomic analyses of CSF aimed at biomarker development for pediatric brain tumors

J. Rutka, B. Raught, D. Malkin, 2014, Journal of Neuro-Oncology.

Predictive genetic testing for childhood cancer: taking the road less traveled by.

D. Malkin, 2004, Journal of pediatric hematology/oncology.

Age-specific oncogenesis: the genetics of cancer susceptibility.

D. Malkin, David Malkin, 1995, Environmental health perspectives.

A family outbreak of hemolytic-uremic syndrome associated with verotoxin-producingEscherichia coli serotype 0157:H7

D. Malkin, M. Petric, M. Karmali, 1988, Pediatric Nephrology.

Parent decision‐making around the genetic testing of children for germline TP53 mutations

A. Patenaude, J. Garber, S. Plon, 2015, Cancer.

A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence

H. Carter, E. Lalli, D. Malkin, 2020, British Journal of Cancer.

Choose and stay on one out of two paths: distinction between clinical versus research genetic testing to identify cancer predisposition syndromes among patients with cancer

D. Malkin, C. Kratz, D. Evans, 2021, Familial Cancer.

Gliomas in the context of Li-Fraumeni syndrome: An international cohort.

D. Evans, T. Slavin, J. Schiffman, 2019, Journal of Clinical Oncology.

Super‐Transactivation TP53 Variant in the Germline of a Family with Li–Fraumeni Syndrome

D. Malkin, A. Novokmet, B. Id Said, 2016, Human mutation.

Germ-line and somatic DICER1 mutations in pineoblastoma

J. Lupski, S. Jhangiani, W. Foulkes, 2014, Acta Neuropathologica.

The Future of Surveillance in the Context of Cancer Predisposition: Through the Murky Looking Glass

S. Plon, J. Schiffman, D. Malkin, 2017, Clinical Cancer Research.

Erratum: Germ-line mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms (New England Journal of Medicine (May 14, 1992))

S. Friend, L. Strong, F. Li, 1997 .

Germ-line mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms.

S. Friend, L. Strong, F. Li, 1997, The New England journal of medicine.

“Balancing Expectations with Actual Realities”: Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial

L. Lau, D. Malkin, K. Hetherington, 2020, Journal of personalized medicine.

Clinical Outcomes of Children With Adrenocortical Carcinoma in the Context of Germline TP53 Status

D. Malkin, J. Wasserman, O. Michaeli, 2020, Journal of pediatric hematology/oncology.

Copy number variations and cancer susceptibility: Retraction.

D. Malkin, 2016, Current opinion in oncology.

The cancer predisposition revolution

S. Friend, L. Strong, J. Garber, 2016, Science.

Genotype Versus Phenotype: The Yin and Yang of Germline TP53 Mutations in Li-Fraumeni Syndrome.

D. Malkin, K. Nichols, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mosaicism in Tumor Suppressor Gene Syndromes: Prevalence, Diagnostic Strategies, and Transmission Risk.

David T. Miller, B. Korf, D. Kwiatkowski, 2022, Annual review of genomics and human genetics.

Surveillance for children at genetic risk for cancer: Are we ready?

D. Malkin, 2014, Pediatric blood & cancer.

Genetic predisposition to cancers in children and adolescents

D. Malkin, Y. Nakano, R. Rabinowicz, 2022, Current opinion in pediatrics.

p53 compound heterozygosity in a severely affected child with Li-Fraumeni Syndrome

C. Portwine, J. Garber, D. Malkin, 1999, Oncogene.

Report of a bi-allelic truncating germline mutation in TP53

N. Brown, D. Malkin, S. White, 2018, Familial Cancer.

Parental attitudes to genetic counseling and predictive testing for childhood cancer.

R. Weksberg, D. Malkin, C. Shuman, 1996, American journal of human genetics.

Inherited TP 53 Mutations and the Li – Fraumeni Syndrome

D. Malkin, Tanya Guha, 2017 .

Cancer surveillance for individuals with Li-Fraumeni syndrome

J. Schiffman, D. Malkin, K. Nichols, 2020, European Journal of Human Genetics.

Li-Fraumeni Syndrome and p53 in 2015: Celebrating their Silver Anniversary.

D. Malkin, 2016, Clinical and investigative medicine. Medecine clinique et experimentale.

Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.

W. Foulkes, N. Hamel, D. Malkin, 2015, Human pathology.

Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome

W. Foulkes, N. Hamel, D. Malkin, 2014, bioRxiv.

Significance of p53 Expression in Immature Teratomas

E. Sexsmith, D. Malkin, P. Charoenkwan, 2002, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Biochemical and imaging surveillance in Li-Fraumeni syndrome - Authors' reply.

D. Malkin, A. Villani, 2016, The Lancet. Oncology.

Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.

D. Malkin, M. Freedman, K. Shannon, 2002, Experimental Hematology.

Li-fraumeni syndrome.

D. Malkin, 2001, Genes & cancer.

Tumour predisposition and cancer syndromes as models to study gene–environment interactions

S. Arron, W. Foulkes, C. Croce, 2020, Nature Reviews Cancer.

Differentiation of rhabdomyosarcoma cell lines using retinoic acid

E. Sexsmith, D. Malkin, A. Narendran, 2006, Pediatric blood & cancer.

Mutations of the p53 gene do not occur in testis cancer.

B. Gallie, J. Buchanan, P. Goss, 1993, Cancer research.

Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms.

S. Friend, A. Look, J. Garber, 1992, The New England journal of medicine.

A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndrome.

D. Malkin, B. Id Said, 2015, Cancer genetics.

Underlying undiagnosed inherited marrow failure syndromes among children with cancer

D. Malkin, E. Bouffet, S. Weitzman, 2017, Pediatric blood & cancer.

Processed pseudogenes acquired somatically during cancer development

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Nature Communications.

Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria

C. Maley, J. Schiffman, D. Malkin, 2023, Cell Death Discovery.

Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.

J. Fraumeni, J. Garber, D. Malkin, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

P. Meltzer, M. Ladanyi, E. Kleinerman, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Nearly Half of TP53 Germline Variants Predicted To Be Pathogenic in Patients With Osteosarcoma Are De Novo: A Report From the Children's Oncology Group.

L. Mirabello, D. Malkin, N. Pankratz, 2020, JCO precision oncology.

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.

David T. W. Jones, R. Weksberg, N. Alon, 2013, The Lancet. Oncology.

The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute

William J. R. Longabaugh, W. Longabaugh, J. Manfredi, 2022, Cell Death & Differentiation.

Inherited TP53 Mutations and the Li-Fraumeni Syndrome.

David Malkin, D. Malkin, Tanya Guha, 2017, Cold Spring Harbor perspectives in medicine.

Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma

Steven J. M. Jones, Ryan D. Morin, Richard A. Moore, 2019, The Journal of pathology.

Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction

G. Koren, S. Baruchel, D. Malkin, 2008, Stem cells.

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

Nicola D. Roberts, Matthew D. Young, S. Scherer, 2018, Science.

Mutations of the p 53 Gene Do Not Occur in Testis Cancer 1

J. Buchanan, P. Goss, M. Jewett, 2006 .

Human Cancer Genetics

D. Malkin, J. Barlow, 2001 .

The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome.

A. Zipursky, D. Malkin, E. Brown, 2000, Cancer genetics and cytogenetics.

Oncogenic ILK, tumor suppression and all that JNK

D. Malkin, G. Hannigan, Adam D. Durbin, 2009, Cell cycle.

The Duality of Tumor Suppressor and Oncogene Functions in Cancer Cells

D. Malkin, G. Hannigan, Adam D. Durbin, 2009 .

The genetics of childhood cancer.

C. Portwine, D. Malkin, 2002, European journal of cancer.

Imaging of cancer predisposition syndromes in children.

P. Babyn, D. Malkin, J. Kapur, 2011, Radiographics : a review publication of the Radiological Society of North America, Inc.

Li-Fraumeni Syndrome: Elucidation of the Mechanisms of Cancer Initiation that Began at Hiroshima:Elucidation of the Mechanisms of Cancer Initiation that Began at Hiroshima

D. Malkin, R. Tsuchida, 2005 .

Germ line BAX alterations are infrequent in Li-Fraumeni syndrome.

L. Strong, J. Varley, D. Malkin, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers

A. Wagers, L. Diller, D. Malkin, 2014, Cancer.

Chapter 1 p 53 and Hereditary Cancer

D. Malkin, D. Merino, Diana M Merino, 2014 .

p53 and hereditary cancer.

D. Malkin, D. Merino, Diana M Merino, 2014, Sub-cellular biochemistry.

TP53 mutations and outcome in osteosarcoma: a prospective, multicenter study.

S. Bull, A. Davis, J. Wunder, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

High frequency of germline p53 mutations in childhood adrenocortical cancer.

C. Portwine, S. Narod, D. Malkin, 1994, Journal of the National Cancer Institute.

Screening for germ line TP53 mutations in breast cancer patients.

S. Friend, E. Hovig, J. Eyfjörd, 1992, Cancer research.

L. Donehower, A. Langerød, L. Strong, 2017, Cancer research.

Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study.

Claudia Eichler-Jonsson, R. Ribeiro, D. Malkin, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Towards an understanding of the role of p53 in adrenocortical carcinogenesis

D. Malkin, G. Zambetti, J. Wasserman, 2012, Molecular and Cellular Endocrinology.

Case-parent analysis of variation in pubertal hormone genes and pediatric osteosarcoma: a Children's Oncology Group (COG) study.

S. Savage, C. Sklar, K. Silverstein, 2012, International journal of molecular epidemiology and genetics.

A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence

H. Carter, E. Lalli, D. Malkin, 2020, British Journal of Cancer.

Predisposition to pediatric and hematologic cancers: a moving target.

J. Schiffman, D. Malkin, K. Nichols, 2014, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network

D. Merico, G. Casallo, T. Paton, 2016, Oncotarget.

Low prevalence of complications in severe neutropenic children with cancer in the unprotected environment of an overnight camp

D. Malkin, U. Tabori, H. Jones, 2007, Pediatric blood & cancer.

A common molecular mechanism underlies two phenotypically distinct 17p13.1 microdeletion syndromes.

M. Shago, P. Hainaut, L. Hudgins, 2010, American journal of human genetics.

The Idea and Evidence for the Tumor Stemness Switch

S. Baruchel, D. Malkin, H. Yeger, 2009 .

p53 and the Li-Fraumeni syndrome.

D. Malkin, David Malkin, 1993, Cancer genetics and cytogenetics.

Absence of Germline and Somatic p53 Alterations in Children with Sporadic Brain Tumors

C. Portwine, E. Sexsmith, D. Malkin, 2001, Journal of Neuro-Oncology.

The Role of P53 in Human Cancer

D. Malkin, 2001, Journal of Neuro-Oncology.

The oncogenic and growth-suppressive functions of the integrin-linked kinase are distinguished by JNK1 expression in human cancer cells

D. Malkin, G. Hannigan, Adam D. Durbin, 2010, Cell cycle.

Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs

Lincoln D. Stein, A. Joyner, M. Marra, 2018, bioRxiv.

Unusual ocular presentation of von Hippel-Lindau disease.

B. Gallie, D. Malkin, E. Héon, 2005, Canadian journal of ophthalmology. Journal canadien d'ophtalmologie.

Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance

W. Foulkes, C. Hawkins, G. Nicholas, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas.

J. Rutka, C. Hawkins, J. Squire, 2006, Neoplasia.

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

L. Strong, S. Pfister, D. Evans, 2017, Clinical Cancer Research.

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.

R. Weksberg, A. Paterson, T. Hudson, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mutant, wild type, or overall p53 expression: freedom from clinical progression in tumours of astrocytic lineage

P. Okunieff, D. Malkin, F. S. Pardo, 2004, British Journal of Cancer.

Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.

David Malkin, Ana Novokmet, Adam Shlien, 2010, Cancer research.

Choroid Plexus Carcinomas and Rhabdoid Tumors: Phenotypic and Genotypic Overlap

Nicholas K. Foreman, David Malkin, Loris McGavran, 2001, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Germ-line p 53 Mutations Predispose to a Wide Spectrum of Early-onset Cancers 1

J. Fraumeni, J. Garber, D. Malkin, 2001 .

Considerations for the use of circulating tumor DNA sequencing as a screening tool in cancer predisposition syndromes

T. Pugh, D. Malkin, A. Villani, 2020, Pediatric blood & cancer.

Connecting molecular pathways to hereditary cancer risk syndromes.

J. Testa, J. Schiffman, D. Malkin, 2013, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Hereditary cancer predisposition in children: Genetic basis and clinical implications

D. Malkin, B. Strahm, 2006, International journal of cancer.

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations.

C. Pui, C. Begg, N. Rothman, 2006, Journal of the National Cancer Institute.

Evaluation of rapid whole-body magnetic resonance as screening strategy for early cancer detection in 57 Brazilian Li-Fraumeni syndrome patients.

D. Malkin, Daniele Paixão, A. Nóbrega, 2015 .

Integrated analysis of cell-free DNA for the early detection of cancer in people with Li-Fraumeni Syndrome

D. Malkin, R. Kim, Y. Sundaravadanam, 2022, medRxiv.

High frequency of de novo mutations in Li–Fraumeni syndrome

D. Malkin, S. Sommer, K. Noltner, 2009, Journal of Medical Genetics.

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging: A Meta-analysis

David M. Thomas, R. Eeles, L. Strong, 2017, JAMA oncology.

Routine TP53 testing for breast cancer under age 30: ready for prime time?

S. Narod, D. Malkin, A. Novokmet, 2012, Familial Cancer.

Genetic predisposition to cancer and familial cancer syndromes.

D. Malkin, S. Quesnel, David Malkin, 1997, Pediatric clinics of North America.

Pediatric Cancer Predisposition and Surveillance: An Overview, and a Tribute to Alfred G. Knudson Jr

S. Plon, J. Schiffman, D. Malkin, 2017, Clinical Cancer Research.

Minimal Residual Disease Evaluation in Childhood Acute Lymphoblastic Leukemia: An Economic Analysis.

D. Johnston, I. Dhalla, D. Malkin, 2016, Ontario health technology assessment series.

Genetic susceptibility and familial cancer syndromes

D. Malkin, M. Diezi, 2003 .

Splice-site mutation of the p53 gene in a family with hereditary breast-ovarian cancer.

A T Look, A. Look, D. Malkin, 1994, Oncogene.

Parents', Health Care Professionals', and Scientists' Experiences of a Precision Medicine Pilot Trial for Patients With High-Risk Childhood Cancer: A Qualitative Study.

L. Lau, D. Malkin, C. Wakefield, 2019, JCO precision oncology.

Pediatric oncologist willingness to offer germline TP53 testing in osteosarcoma

D. Malkin, R. Gorlick, D. Geller, 2018, Cancer.

Li-Fraumeni Exploration Consortium Data Coordinating Center: Building an Interactive Web-Based Resource for Collaborative International Cancer Epidemiology Research for a Rare Condition

Sharon Sand, Judy Garber, Xianhua Kong, 2020, Cancer Epidemiology, Biomarkers & Prevention.

Tumor surveillance for children and adolescents with cancer predisposition syndromes: The psychosocial impact reported by adolescents and caregivers

D. Chitayat, D. Malkin, Bailey Gallinger, 2021, Pediatric blood & cancer.

New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort

M. Kattan, K. Siminovitch, J. Trachtenberg, 2011, Cancer biology & therapy.

The cycle of genome-directed medicine

S. Scherer, A. Carson, R. Weksberg, 2009, Genome Medicine.

A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma.

Herman Yeger, David Malkin, M. Shibuya, 2005, Cancer research.

Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk

Nardin Samuel, Thomas J Hudson, David Malkin, 2017, Human mutation.

p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis

J. Gariépy, D. Malkin, Nicholas W. Fischer, 2016, Cell cycle.

The Genetics of Cancer

D. Malkin, 1995, Cancer Biology and Medicine.

Aggressive embryonal rhabdomyosarcoma in a 3-month-old boy: A clinical and molecular analysis

M. Shago, S. Hopyan, A. Shlien, 2018, Pediatric hematology and oncology.

A pilot study of low‐dose anti‐angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: A Children's Oncology Group (COG) Phase II study NCT00061893

S. Baruchel, D. Malkin, M. Bernstein, 2013, Pediatric blood & cancer.

P53 expression in choroid plexus neoplasms: an immunohistochemical study.

V. Jay, D. Malkin, V Jay, 1996, Archives of pathology & laboratory medicine.

Drug-induced aplastic anemia: pathogenesis and clinical aspects.

D. Malkin, G. Koren, E. Saunders, 1990, American Journal Of Pediatric Hematology/Oncology.

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer.

P. D. Lee, S. Mousses, I. Andrulis, 1995, Human Molecular Genetics.

The role of tumour suppressor genes in familial cancer.

S. Friend, D. Malkin, 1992, Seminars in cancer biology.

Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium.

A. Patenaude, L. Strong, M. Greene, 2012, Cancer genetics.

TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy

M. Fassan, J. Gariépy, V. Catalano, 2020, Cancers.

Tissue-specific expression of SV40 in tumors associated with the Li–Fraumeni syndrome

R. Garcea, L. Diller, E. Sexsmith, 2001, Oncogene.

Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database

E. Erhardt, S. Plon, Heather E. Danysh, 2015, Cancer medicine.

Childhood erythroleukemia: review of clinical and biological features.

D. Malkin, M. Freedman, 1989, The American journal of pediatric hematology/oncology.

CanDIG: Secure Federated Genomic Queries and Analyses Across Jurisdictions

Steven J. M. Jones, M. Brudno, P. Quirion, 2021, bioRxiv.

Tumour predisposition and cancer syndromes as models to study gene–environment interactions

S. Arron, W. Foulkes, C. Croce, 2020, Nature Reviews Cancer.

Predictors and mediators of psychological adjustment in mothers of children newly diagnosed with cancer

R. Weksberg, D. Malkin, M. Barrera, 2004, Psycho-oncology.

Comprehensive characterization of a Canadian cohort of von Hippel‐Lindau disease patients

S. Asa, S. Ezzat, G. Zadeh, 2019, Clinical genetics.

P53: an old dog begins to learn new tricks.

D. Malkin, 2003, Drug discovery today.

Performance of the eHealth decision support tool, MIPOGG, for recognising children with Li-Fraumeni, DICER1, Constitutional mismatch repair deficiency and Gorlin syndromes

D. Johnston, W. Foulkes, D. Malkin, 2023, Journal of medical genetics.

Precision oncology for children: A primer for paediatricians

D. Malkin, A. Denburg, D. Morgenstern, 2023, Paediatrics & Child Health.

The genetics of childhood cancer.

David Malkin, Hooman Ganjavi, C. Portwine, 1994, European journal of cancer.

Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs

Nada Jabado, Alexandra L. Joyner, Trevor J Pugh, 2018, Nature.

Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial

Katherine M. Tucker, M. Cowley, M. Pinese, 2023, Journal of Personalized Medicine.

Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome.

J. Gariépy, D. Malkin, Nicholas W. Fischer, 2018, Journal of the National Cancer Institute.

Report of a bi-allelic truncating germline mutation in TP53

N. Brown, D. Malkin, S. White, 2018, Familial Cancer.

Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition.

S. Plon, J. Schiffman, L. Diller, 2022, Cancer Prevention Research.

Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction

G. Koren, S. Baruchel, D. Malkin, 2008, Stem cells.

Correction: A Li-Fraumeni Syndrome p53 Mutation

S. Friend, D. Malkin, 1993, Science.

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations.

C. Pui, C. Begg, N. Rothman, 2006, Journal of the National Cancer Institute.

The Future of Surveillance in the Context of Cancer Predisposition: Through the Murky Looking Glass

S. Plon, J. Schiffman, D. Malkin, 2017, Clinical Cancer Research.

S. Baruchel, D. Malkin, M. Bernstein, 2013, Pediatric blood & cancer.

Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.

A. Shlien, D. Malkin, P. Ray, 2010, Cancer research.