M. Rusch

发表

Targeting oxidative stress in embryonal rhabdomyosarcoma.

Heather L. Mulder, Erin K. Hedlund, Sara M. Federico, 2013, Cancer cell.

The genomic landscape of hypodiploid acute lymphoblastic leukemia

Robert Huether, Jinghui Zhang, Matthew Parker, 2013, Nature Genetics.

Pediatric Cancer Variant Pathogenicity Information Exchange (PeCanPIE): a cloud-based platform for curating and classifying germline variants

Aman N. Patel, J. Downing, M. Edmonson, 2018, bioRxiv.

Integrated cross-species transcriptional network analysis of metastatic susceptibility

Michael C. Rusch, Jinghui Zhang, K. Buetow, 2012, Proceedings of the National Academy of Sciences.

Reply to Artifacts in the data of Hu et al.

Jinghui Zhang, Aman N. Patel, Matthew Parker, 2015, Nature Genetics.

Relapse fated latent diagnosis subclones in acute B lineage leukaemia are drug tolerant and possess distinct metabolic programs.

Gary D Bader, Michael C. Rusch, Michael N. Edmonson, 2020, Cancer discovery.

Germline Elongator mutations in Sonic Hedgehog medulloblastoma

Jennifer L. Hadley, David T. W. Jones, Jules N. A. Kerssemakers, 2020, Nature.

CREST maps somatic structural variation in cancer genomes with base-pair resolution

Michael C. Rusch, R. Wilson, E. Mardis, 2011, Nature Methods.

CONSERTING: integrating copy-number analysis with structural-variation detection

Aman N. Patel, Michael C. Rusch, J. Downing, 2015, Nature Methods.

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2013, Nature Genetics.

A Novel Retinoblastoma Therapy from Genomic and Epigenetic Analyses

Matthew W. Wilson, Michael C. Rusch, R. Wilson, 2011, Nature.

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

R. Wilson, E. Mardis, J. Downing, 2012, Genome Biology.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Kiran C. Bobba, Kimberly J. Johnson, Michael C. Rusch, 2012, Nature.

RNAIndel: discovering somatic coding indels from tumor RNA-Seq data

Michael C. Rusch, Michael N. Edmonson, M. Edmonson, 2019, bioRxiv.

RNAIndel: discovering somatic coding indels from tumor RNA-Seq data

M. Edmonson, R. Ries, S. Meshinchi, 2019, bioRxiv.

A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.

Heather L. Mulder, Jason R. Hodges, Celeste K. Kanne, 2021, Blood advances.

Novel mutations target distinct subgroups of medulloblastoma

Elaine R. Mardis, Timothy N. Phoenix, Amar Gajjar, 2012, Nature.

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia

Jing Ma, Xiaotu Ma, Jinghui Zhang, 2015, Nature Communications.

THE GENOMIC LANDSCAPE OF PEDIATRIC AND YOUNG ADULT T-LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA

Cheng Cheng, Edgar Sioson, Xiaotu Ma, 2017, Nature Genetics.

Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.

Michael C. Rusch, Michael N. Edmonson, M. Relling, 2020, Blood cancer discovery.

Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma.

Li Ding, Jinghui Zhang, Matthew Parker, 2014, Cell reports.

Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

Michael C. Rusch, Michael N. Edmonson, M. Edmonson, 2020, Nature Genetics.

Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo

Beisi Xu, D. Ellison, T. Shaw, 2019, Acta Neuropathologica.

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

Michael C. Rusch, M. Prados, T. Curran, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.

Benjamin J. Raphael, Heather L. Mulder, Diane A. Flasch, 2019, Blood.

CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data

J. Downing, M. Edmonson, Jing Ma, 2020, Genome Biology.

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Anna L. Brown, Michael C. Rusch, M. Loh, 2019, Nature Genetics.

Nature Genetics Advance Online Publication

Heather L. Mulder, Erin K. Hedlund, R. Wilson, 2022 .

Erratum: C11orf95-RELA fusions drive oncogenic NF-Î° B signalling in ependymoma (Nature (2014) 506 (451-455 ) DOI:10.1038/nature13109)

Erin K. Hedlund, Michael C. Rusch, R. Wilson, 2014 .

Estimated number of adult survivors of childhood cancer in United States with cancer‐predisposing germline variants

Aman N. Patel, Heather L. Mulder, Carmen L. Wilson, 2019, Pediatric blood & cancer.

Genomic Characterization and Experimental Modeling Of BCR-ABL1 -Like Acute Lymphoblastic Leukemia

Michael C. Rusch, M. Loh, J. Downing, 2013 .

St. Jude Cloud—a Pediatric Cancer Genomic Data Sharing Ecosystem

Aman N. Patel, Carmen L. Wilson, Samuel W. Brady, 2020, bioRxiv.

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.

M. Loh, J. Downing, J. McPherson, 2016, Cancer cell.

Abstract 4869: Whole genome sequence analysis of MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: A Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project

Michael C. Rusch, R. Wilson, E. Mardis, 2012 .

The genomic landscape of pediatric acute lymphoblastic leukemia

Diane A. Flasch, Samuel W. Brady, Michael C. Rusch, 2022, Nature Genetics.

Inhibition of SF3B1 by molecules targeting the spliceosome results in massive aberrant exon skipping

Michael C. Rusch, Michael N. Edmonson, M. Edmonson, 2018, RNA.

Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“Ph-like” or “BCR-ABL1-Like”) Signature For Therapeutic Targeting and Clinical In

Michael C. Rusch, M. Loh, D. Gerhard, 2013 .

XenoCP: Cloud-based BAM cleansing tool for RNA and DNA from Xenograft

M. Rusch, Jinghui Zhang, M. Dyer, 2019, bioRxiv.

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2014, The New England journal of medicine.

scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data

Michael C. Rusch, Koon-Kiu Yan, H. Chi, 2023, bioRxiv.

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

Amar Gajjar, Robert Huether, Xiaotu Ma, 2014, Nature Genetics.

Germline Mutations in Predisposition Genes in Pediatric Cancer.

Li Ding, Amar Gajjar, Xiaotu Ma, 2015, The New England journal of medicine.

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo

Michael C. Rusch, Beisi Xu, D. Ellison, 2019, Acta Neuropathologica.

C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma

Li Ding, Elaine R. Mardis, Timothy N. Phoenix, 2014, Nature.

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2014, Nature Communications.

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Heather L. Mulder, Michael C. Rusch, R. Wilson, 2016, Acta Neuropathologica.

The landscape of somatic mutations in Infant MLL rearranged acute lymphoblastic leukemias

Cheng Cheng, Li Ding, Robert Huether, 2015, Nature Genetics.

An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.

Heather L. Mulder, S. Ranade, R. Wilson, 2012, Cancer cell.

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.

Li Ding, Xiaotu Ma, Jinghui Zhang, 2014, Cancer discovery.

The genomic landscape of core-binding factor acute myeloid leukemias

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2016, Nature Genetics.

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Elizabeth Stewart, Jinghui Zhang, Heather L. Mulder, 2018, Cancer cell.

Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors

Xin Zhou, Charles Gawad, Li Dong, 2018, Nature.

St. Jude Cloud-a Pediatric Cancer Genomic Data Sharing Ecosystem.

Aman N. Patel, Carmen L. Wilson, Samuel W. Brady, 2021, Cancer discovery.

The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment

Benjamin J. Raphael, Heather L. Mulder, Samuel W. Brady, 2019, Molecular Cancer Research.

Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

Aman N. Patel, Samuel W. Brady, Michael C. Rusch, 2021, Cancer discovery.

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

Heather L. Mulder, Samuel W. Brady, Michael C. Rusch, 2020, Nature Communications.

Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

Xiaotu Ma, Jinghui Zhang, Scott Newman, 2018, Nature Communications.

Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers.

Carmen L. Wilson, Michael C. Rusch, Michael N. Edmonson, 2019, Journal of the National Cancer Institute.

Pathogenic Germline Mutations in DNA Repair Genes in Combination With Cancer Treatment Exposures and Risk of Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer.

Heather L. Mulder, Carmen L. Wilson, J. Downing, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Structure and evolution of double minutes in diagnosis and relapse brain tumors

Heather L. Mulder, Michael C. Rusch, J. Downing, 2018, Acta Neuropathologica.

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

Taosheng Chen, Junmin Peng, Jing Ma, 2015, Cancer cell.

CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data

J. Downing, M. Edmonson, Jing Ma, 2020, Genome Biology.

Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia

Michael C. Rusch, J. Downing, M. Babu, 2022, Blood cancer discovery.

Shortened Leukocyte Telomere Length Associates with an Increased Prevalence of Chronic Health Conditions among Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort

Heather L. Mulder, Carmen L. Wilson, Michael C. Rusch, 2020, Clinical Cancer Research.

Polygenic Determinants for Subsequent Breast Cancer Risk in Survivors of Childhood Cancer: The St Jude Lifetime Cohort Study (SJLIFE)

Heather L. Mulder, Carmen L. Wilson, J. Downing, 2018, Clinical Cancer Research.

MLL Rearrangements Impact Outcome in HOXA-deregulated T-lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

Michael C. Rusch, M. Loh, N. Heerema, 2016, Leukemia.

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

Heather L. Mulder, Michael C. Rusch, Michael N. Edmonson, 2016, Nature Genetics.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

Rohini Rau-Murthy, Jinghui Zhang, Kenneth Offit, 2013, Nature Genetics.

Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

Aman N. Patel, Erin K. Hedlund, J. Downing, 2018, Nature Communications.

RNAIndel: discovering somatic coding indels from tumor RNA-Seq data.

Liang Ding, Stephen V. Rice, Rhonda E. Ries, 2019, Bioinformatics.

Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

M. Edmonson, A. Look, J. Easton, 2020, Nature Genetics.

AMKL chimeric transcription factors are potent inducers of leukemia

Michael C. Rusch, J. Downing, A. Gedman, 2017, Leukemia.

Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project

Kiran C. Bobba, Kimberly J. Johnson, R. Wilson, 2011 .

The landscape of coding RNA editing events in pediatric cancer

Samuel W. Brady, M. Edmonson, Ji-Rong Wen, 2021, BMC Cancer.

Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation

Michael C. Rusch, A. Kanagaraj, J. Taylor, 2016, Scientific Reports.

Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer.

Yadav Sapkota, Celeste Rosencrance, Xiaotu Ma, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Exploration of Coding and Non-coding Variants in Cancer Using GenomePaint.

Diane A. Flasch, Samuel W. Brady, M. Edmonson, 2021, Cancer cell.

Germline Elongator mutations in Sonic Hedgehog medulloblastoma

Jennifer L. Hadley, David T. W. Jones, Jules N. A. Kerssemakers, 2020, Nature.

The Genomic Landscape of Childhood and Adolescent Melanoma

Li Ding, Jinghui Zhang, Matthew Parker, 2014, The Journal of investigative dermatology.

Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes

Heather L. Mulder, Michael C. Rusch, Michael N. Edmonson, 2017, Nature Genetics.

Data Access and Interactive Visualization of Whole Genome Sequence of Sickle Cell Patients within the St. Jude Cloud

Jian Wang, John Easton, Michael Rusch, 2018, Blood.

NetBID2 provides comprehensive hidden driver analysis

Michael C. Rusch, Xinran Dong, J. Liu, 2023, Nature communications.

Corrigendum: C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma

Heather L. Mulder, Erin K. Hedlund, R. Wilson, 2014, Nature.

Abstract 2289: Empowering point-and-click genomic analysis with large pediatric genomic reference data on St. Jude Cloud

Michael A. Dyer, Jinghui Zhang, Delaram Rahbarinia, 2021, Molecular and Cellular Biology/Genetics.

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Anna L. Brown, M. Loh, Cheng Cheng, 2019, Nature Genetics.

Mixed Lineage Leukemia Rearrangements (MLL-R) Are Determinants of High Risk Disease in Homeobox A (HOXA)-deregulated T-Lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

M. Loh, N. Heerema, J. Soulier, 2015 .

Abstract 2980: An integrated cross-species transcriptional network analysis of metastatic susceptibility

Jinghui Zhang, K. Buetow, Ying Hu, 2012 .

Nature GeNetics ADVANCE ONLINE PUBLICATION

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2013 .

Incidence of Germline Mutations in Cancer-Predisposition Genes in Children with Hematologic Malignancies: a Report from the Pediatric Cancer Genome Project

Erin K. Hedlund, E. Mardis, J. Downing, 2014 .

Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

M. Loh, J. Downing, M. Relling, 2013 .

The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia

M. Loh, J. Downing, M. Relling, 2015 .

Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the St Jude Children‘s Research Hospital - Washington University Pediatric Cancer Genome Project

Michael C. Rusch, E. Mardis, J. Downing, 2011 .

RNAIndel: a machine-learning framework for discovery of somatic coding indels using tumor RNA-Seq data

Michael C. Rusch, Michael N. Edmonson, M. Edmonson, 2018 .