J. Kane

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A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

Scott F. Saccone, P. Kwok, A. Barton, 2008, PLoS genetics.

Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death.

H. Harris, K. Feingold, J. Kane, 1993, The Journal of clinical investigation.

Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study.

J. Pankow, E. Boerwinkle, L. Chambless, 2007, American journal of epidemiology.

Identification of four gene variants associated with myocardial infarction.

E. Topol, J. Catanese, Diane U. Leong, 2005, American journal of human genetics.

Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity

P. Kwok, L. Pennacchio, W. Rief, 2005, PLoS biology.

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS

M. Wurfel, J. Kane, S. Wright, 1994, The Journal of experimental medicine.

Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins.

J P Kane, P. Fitzgerald, P. Yock, 1996, Journal of the American College of Cardiology.

Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia Published, JLR Papers in Press, December 30, 2005.

C. Eng, M. Malloy, C. Pullinger, 2006, Journal of Lipid Research.

Human cholesterol 7a-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype

C. Eng, M. Malloy, C. Pullinger, 2018 .

Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding.

V. Schumaker, C. Packard, C. Pullinger, 2002, Clinica chimica acta; international journal of clinical chemistry.

Effects of a 3-day fast and of ethanol on splanchnic metabolism of FFA, amino acids, and carbohydrates in healthy young men.

J. Kane, S. Ahuja, E. Marliss, 1976, The Journal of clinical investigation.

Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility.

J. Kane, S. Kunitake, K. J. La Sala, 1985, Journal of lipid research.

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.

J. Kane, D. Hardman, H. Paulus, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis

P. Kwok, Dedeepya Vaka, Nina Gonzaludo, 2019, Molecular Genetics & Genomic Medicine.

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.

L. Pennacchio, R. McPherson, N. Ahituv, 2009, Human molecular genetics.

Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency.

C. Sirlin, G. Hamilton, G. Enns, 2014, Journal of hepatology.

Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients With cholesteryl ester storage disease

G. Enns, J. Kane, M. Balwani, 2013, Hepatology.

Chylomicrons enhance endotoxin excretion in bile

H. Harris, K. Feingold, J. Kane, 1993, Infection and immunity.

Triglyceride-rich lipoproteins prevent septic death in rats

K. Feingold, J. Kane, C. Grunfeld, 1995, The Journal of experimental medicine.

Normalization of low-density-lipoprotein levels in heterozygous familial hypercholesterolemia with a combined drug regimen.

M J Malloy, J P Kane, R J Havel, 1981, The New England journal of medicine.

Treatment of hypercholesterolemia.

R. Havel, M. Malloy, J. Kane, 1982, The Medical clinics of North America.

Mechanism of the hypolipemic effect of clofibrate in postabsorptive man.

R. Havel, J. Kane, B. Wolfe, 1973, The Journal of clinical investigation.

Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia.

R. Havel, J. Kane, A. Pagnan, 1977, Journal of lipid research.

Radiation inactivation of binding sites for high-density lipoproteins in human liver membranes.

J. Kane, E. Kempner, S. Kunitake, 1988, Biochimica et biophysica acta.

Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans.

R. Havel, J. Kane, E. Balasse, 1970, The Journal of clinical investigation.

HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property

A. Burlingame, J. Michel, J. Kane, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characteristics of human lipoproteins isolated by selected-affinity immunosorption of apolipoprotein A-I.

J. Kane, S. Kunitake, J. Mcvicar, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption.

J. Kane, A. Protter, S. Kunitake, 1994, Biochemistry.

Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque.

R. Havel, J. Kane, J. Rapp, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

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J. Kane, G. Cooper, P. Wood, 1982 .

The Effect of Chronic Oral Antidiabetic Therapy on Insulin and Glucagon Responses to a Meal

E. Tsalikian, J. Kane, M. Lorenzi, 1977, Diabetes.

An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish

Rahul C. Deo, P. Kwok, R. Deo, 2015, eLife.

Apolipoprotein B (B-48) of rat chylomicrons is not a precursor of the apolipoprotein of low density lipoproteins.

F. V. van’t Hooft, R. Havel, J. Kane, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Contribution of carotenoids to the optical activity of human serum low-density lipoprotein.

J. Kane, G. Chen, 1974, Biochemistry.

Isoelectric heterogeneity of the cofactor protein for lipoprotein lipase in human blood plasma.

R. Havel, J. Kane, L. Kotite, 1979, Biochemical medicine.

Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man.

R. Havel, J. Kane, M. Kashyap, 1973, The Journal of clinical investigation.

Apoprotein composition of very low density lipoproteins of human serum.

R. Havel, J. Kane, R. Hamilton, 1975, The Journal of clinical investigation.

Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency.

R. Havel, J. Kane, J. Vigne, 1980, The Journal of clinical investigation.

Factors affecting the integrity of high density lipoproteins in the ultracentrifuge.

J. Kane, S. Kunitake, 1982, Journal of lipid research.

Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties.

C. Rowland, M. Malloy, C. Pullinger, 2014, Thrombosis research.

Impact of a 4q25 Genetic Variant in Atrial Flutter and on the Risk of Atrial Fibrillation After Cavotricuspid Isthmus Ablation

J. Olgin, G. Marcus, M. Malloy, 2014, Journal of cardiovascular electrophysiology.

Levels of Prebeta‐1 High‐Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta‐Analysis

M. Malloy, C. Pullinger, J. Kane, 2021, Journal of the American Heart Association.

Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype.

R. Mahley, M. Malloy, J. Kane, 2000, Journal of lipid research.

Levels and Interrelationships of Serum and Lipoprotein Cholesterol and Triglycerides

R. Havel, J. Kane, N. Phillips, 1981, Arteriosclerosis.

Natural History and Biology of Atherosclerosis

J. Kane, 1982, IEEE Transactions on Nuclear Science.

The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients.

A. Goldberg, J. Kane, T. A. Hughes, 1995, Atherosclerosis.

Bladder cancer and squamous metaplasia in spinal cord injury patients.

A. Rossier, J. Kane, S. Jacobs, 1977, The Journal of urology.

Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man.

K. Korach, M. Malloy, J. Kane, 1997, Circulation.

Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus.

M. Malloy, C. Pullinger, J. Kane, 2021, Current opinion in pharmacology.

Biochemical Analysis of the LPL Truncation Variant, LPL S447X Reveals Increased Lipoprotein Uptake

J. Kane, Cassandra K. Hayne, M. Lafferty, 2018 .

Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake.

S. Neher, J. Kane, Cassandra K. Hayne, 2017, Biochemistry.

The primary stone event: a new hypothesis involving a vascular etiology.

M. Meng, M. Stoller, J. Kane, 2004, The Journal of urology.

Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia.

P. Yock, J. Goldberger, M. Malloy, 1995, Circulation.

Moderate statin treatment reduces prebeta-1 high-density lipoprotein levels in dyslipidemic patients.

M. Malloy, C. Pullinger, J. Kane, 2017, Journal of clinical lipidology.

Genetic Variation in PLTP Modulates Lipoprotein Profiles in Hyperalphalipoproteinemia

C. Eng, M. Malloy, C. Pullinger, 2022 .

Polymorphisms and Noncardioembolic Stroke in Three Case-Control Studies

E. Ringelstein, J. Catanese, V. Garcia, 2011, Cerebrovascular Diseases.

Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene.

R. Havel, M. Malloy, J. Kane, 1991, The Journal of clinical investigation.

Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib.

D. Rader, H. Brewer, S. Nissen, 2015, Journal of the American College of Cardiology.

Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL Published, JLR Papers in Press, December 16, 2004. DOI 10.1194/jlr.M400304-JLR200

P. Duchateau, S. Deeb, M. Malloy, 2005, Journal of Lipid Research.

Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067.

J. Kane, R. Scott, M. Davidson, 2007, Journal of clinical lipidology.

Apolipoprotein B: structural and metabolic heterogeneity.

J. Kane, 1983, Annual review of physiology.

Clonal hematopoiesis is driven by aberrant activation of TCL1A

Andrew D. Johnson, Nicholette D. Palmer, Ansuman T. Satpathy, 2021, bioRxiv.

Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method

C. Pullinger, J. Kane, A. Gugliucci, 2019, Journal of Lipid Research.

Isolation of subpopulations of high density lipoproteins: three particle species containing apoE and two species devoid of apoE that have affinity for heparin.

J. Kane, A. Protter, S. Kunitake, 1997, Journal of lipid research.

Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles.

J. Kane, S. Kunitake, L. Hennessy, 1993, Biochemistry.

Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity.

Weiqun, V. Schumaker, M. Malloy, 1995, The Journal of clinical investigation.

A single copy of apolipoprotein B-48 is present on the human chylomicron remnant.

V. Schumaker, I. Kroes, C. Pullinger, 1997, Journal of lipid research.

Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection?

R. Havel, J. Kane, 1999, Circulation.

Therapy of hyperlipidemic states.

R. Havel, J. Kane, 1982, Annual review of medicine.

Drugs and lipid metabolism.

R. Havel, J. Kane, 1973, Annual review of pharmacology.

Remnants of Lipoproteins of Intestinal and Hepatic Origin in Familial Dysbetalipoproteinemia

R. Havel, M. Malloy, J. Kane, 1983, Arteriosclerosis.

Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification.

J. Kane, R. Ockner, J. Manning, 1982, The Journal of biological chemistry.

Metabolism of apoprotein B of plasma very low density lipoproteins in the rat.

O. Faergeman, R. Havel, J. Kane, 1975, The Journal of clinical investigation.

A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins.

J. Kane, 1973, Analytical biochemistry.

Lowering Lipids Improves Coronary Arterial Anatomy-Reply

J. Kane, 1991 .

Serum apolipoprotein A-I levels: relationship to lipoprotein lipid levels and selected demographic variables.

R. Havel, J. Kane, N. Phillips, 1982, American journal of epidemiology.

Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy

K. Weisgraber, J. Kane, H. Pownall, 2010 .

The Online Metabolic and Molecular Bases of Inherited Disease > 114 : Introduction : Structure and Metabolism of Plasma Lipoproteins

R. Havel, J. Kane, 2017 .

Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects.

P. Duchateau, S. Yamashita, Y. Matsuzawa, 2000, Journal of lipid research.

Normocholesterolemic dysbetalipoproteinemia with xanthomatosis.

S. Grundy, J. Kane, C. M. Chang, 1979, Metabolism: clinical and experimental.

Plasma Lipoproteins: Structure and Metabolism

J. Kane, 1977 .

Distribution of lipid-binding regions in human apolipoprotein B-100.

J. Kane, J. Schilling, J. Wong, 1989, Biochemistry.

Discrimination between subclasses of human high-density lipoproteins by the HDL binding sites of bovine liver.

J. Kane, S. Kunitake, C. Mendel, 1986, Biochimica et biophysica acta.

Metabolism of Lipid and Protein Components of Triglyceride-Rich Lipoproteins in Rats and Humans

R. Havel, J. Kane, A. Pagnan, 1976 .

Lipid and Lipoprotein Metabolism

C. Pullinger, J. Kane, 2006 .

Levels of prebeta-1 high-density lipoprotein are elevated in 3 phenotypes of dyslipidemia.

M. Malloy, C. Pullinger, J. Kane, 2017, Journal of clinical lipidology.

Pre-beta high density lipoprotein. Unique disposition of apolipoprotein A-I increases susceptibility to proteolysis.

J. Kane, J. Schilling, S. Kunitake, 1990, Arteriosclerosis.

Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts.

S. Baranzini, C. Pullinger, J. Kane, 2003, Biochemical and biophysical research communications.

Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits.

R. Havel, J. Kane, C. Hornick, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Aberrant Hetero-Disulfide Bond Formation by the Hypertriglyceridemia-Associated p.Gly185Cys APOA5 Variant (rs2075291)

H. Witkowska, M. Malloy, C. Pullinger, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.

R. Havel, J. Kane, T. Bersot, 1983, The Journal of clinical investigation.

Concentration and Composition of Lipoproteins in Blood Plasma of the WHHL Rabbit

R. Havel, T. Kita, J. Kane, 1982, Arteriosclerosis.

Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein.

M. Malloy, J. Kane, K. Dalal, 1981, The Journal of clinical investigation.

Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in normal and lipoprotein lipase-deficient humans.

R. Havel, M. Malloy, J. Kane, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats.

K. Feingold, J. Kane, C. Grunfeld, 1995, Surgery.

Chylomicrons can inhibit endotoxin activity in vitro.

H. Harris, J. Kane, E. Eichbaum, 1991, The Journal of surgical research.

Plasma lipoproteins and their receptors

J. Kane, 1991 .

Stability of the apoprotein of human serum low density lipoprotein: absence of endogenous endopeptidase activity.

J. Kane, M. Chapman, 1975, Biochemical and biophysical research communications.

Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia.

R. Havel, M. Malloy, J. Kane, 1986, The Journal of clinical investigation.

Characterization of apolipoprotein B-containing lipoproteins.

J. Kane, 1986, Methods in enzymology.

Antigen-specific nonimmunoglobulin factor that neutralizes xenotropic virus is associated with mouse serum lipoproteins.

J. Levy, J. Kane, J. Leong, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Lipoproteins and amyloid vascular disease.

M. Malloy, J. Kane, 2016, Current opinion in lipidology.

Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia

J. Kane, D. Lütjohann, K. von Bergmann, 2004, Circulation.

Emerging roles of qualitative properties of lipoproteins in atherosclerosis.

M. Malloy, J. Kane, 2014, Current opinion in lipidology.

patient-oriented and epidemiological research An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients

P. Kwok, E. Sijbrands, R. Havel, 2008 .

Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity.

E. Schaefer, K. Weisgraber, J. Kane, 1991, Journal of lipid research.

Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B.

J. Kane, J. Schilling, A. Protter, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy.

H. Calkins, D. Judge, P. Ganz, 2012, Heart rhythm.

beta-Carotene as a probe of lipid domains of reconstituted human plasma low-density lipoprotein: induced circular dichroism.

M. Krieger, J. Kane, M. Brown, 1980, Biochemistry.

Identification of apolipoprotein B100 polymorphisms that affect low-density lipoprotein metabolism: description of a new approach involving monoclonal antibodies and dynamic light scattering.

V. Schumaker, C. Pullinger, J. Kane, 1995, Biochemistry.

Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia.

M. Malloy, C. Pullinger, J. Kane, 1991, The Journal of clinical investigation.

Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination.

J. Kane, J. Schilling, A. Protter, 1987, Biochemical and biophysical research communications.

Xenosterolemia: emerging molecular and clinical insights.

M. Malloy, J. Kane, E. Schaefer, 2017, Current opinion in lipidology.

Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report.

L. Reilly, R. Stoney, W. Ehrenfeld, 1989, Journal of vascular surgery.

Machine learning and statistical approaches for classification of risk of coronary artery disease using plasma cytokines

M. Malloy, J. Kane, K. Creasy, 2020, BioData Min..

Elastin Degradation and Lung Function Deterioration with Remote Secondhand Tobacco Smoke Exposure in Never-smokers.

R. Redberg, J. Kane, G. Turino, 2022, Chronic obstructive pulmonary diseases.

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Matti Pirinen, Christian Gieger, Peter Donnelly, 2012 .

Identification and metabolic profiling of patients with lysosomal acid lipase deficiency.

E. Schaefer, M. Malloy, C. Pullinger, 2015, Journal of clinical lipidology.

The protective effect of serum lipoproteins against bacterial lipopolysaccharide.

H. Harris, K. Feingold, J. Kane, 1993, European heart journal.

Sebelipase alfa for lysosomal acid lipase deficiency: 5‐year treatment experience from a phase 2 open‐label extension study

J. Kane, M. Balwani, C. Whitley, 2020, Liver international : official journal of the International Association for the Study of the Liver.

The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion

M. Malloy, C. Pullinger, J. Kane, 2006, Lipids in Health and Disease.

A risk factor for atherosclerosis: triglyceride-rich lipoproteins.

M. Malloy, J. Kane, John P. Kane, 2001, Advances in internal medicine.

Prolonged effects of tumor necrosis factor-α on anterior pituitary hormone release

J. Kane, M. Szabo, J. Magner, 1995, Peptides.

Prolonged effects of tumor necrosis factor-alpha on anterior pituitary hormone release.

J. Kane, M. Szabo, J. Magner, 1995, Peptides.

Implementation of PCA enabled Support Vector Machine using cytokines to differentiate smokers versus nonsmokers.

M. Malloy, J. Kane, K. Creasy, 2021, 2021 International Conference on Computational Science and Computational Intelligence (CSCI).

JCL Roundtable: diagnosis of severe familial hypercholesterolemia.

D. Rader, J. Kane, W. Brown, 2013, Journal of clinical lipidology.

Vitamin E-enriched lipoproteins increase longevity of neurons in vitro.

M. Halks-Miller, J. Kane, E. Smuckler, 1981, Brain research.

Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study

Thomas Lumley, Kenneth Rice, Bruce M Psaty, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Neutralization of mouse xenotropic virus by lipoproteins involves binding to the virions.

J. Levy, J. Kane, D. Hardman, 1988, The Journal of general virology.

A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin.

P. Duchateau, M. Malloy, C. Pullinger, 1997, Journal of lipid research.

Human apolipoprotein C-I: concentration in blood serum and lipoproteins.

R. Havel, J. Kane, L. Kotite, 1980, Biochemical medicine.

A variant primary structure of apolipoprotein C-II in individuals of African descent.

R. Havel, M. Malloy, J. Kane, 1986, The Journal of clinical investigation.

Hyperlipidemia and cardiovascular disease.

M. Malloy, J. Kane, 2012, Current opinion in lipidology.

The apolipoprotein B Q3405E polymorphism has no effect on its low-density-lipoprotein receptor binding affinity

D. Illingworth, C. Pullinger, J. Kane, 1996, Human Genetics.

Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins.

R. Havel, J. Kane, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Emerging molecular strategies for management of dyslipidemias.

M. Malloy, J. Kane, 2015, Current opinion in lipidology.

Synergism in Drug Treatment of Familial Hypercholesterolemia

R. Havel, M. Malloy, J. Kane, 1980 .

Splanchnic metabolism in von Gierke's disease (glycogenosis type I).

R. Havel, J. Kane, E. Balasse, 1969, Transactions of the Association of American Physicians.

Detection of endotoxin in triglyceride-rich lipoproteins in vitro.

H. Harris, J. Kane, E. Eichbaum, 1991, The Journal of laboratory and clinical medicine.

Apolipoprotein is responsible for neutralization of xenotropic type C virus by mouse serum.

J. Levy, J. Kane, D. Hardman, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Quantification of triglyceride transport in blood plasma: a critical analysis.

R. Havel, J. Kane, 1975, Federation proceedings.

Does hypertriglyceridemia present an indication for pioglitazone therapy in diabetes?

J. Kane, 2002, Diabetes technology & therapeutics.

Running title: Stitziel et al., Exome Sequencing in Monogenic Dyslipidemias

S. Gabriel, M. Daly, D. Nickerson, 2015 .

Molecular weight distributions of polydisperse systems: application to very low density lipoproteins.

V. Schumaker, C. Knobler, J. Kane, 1978, Biochemistry.

Apolipoprotein and size heterogeneity in human umbilical cord blood low density lipoproteins.

R. Krauss, C. Blum, J. Kane, 1983, Biochimica et biophysica acta.

[12] Isolation and characterization of apolipoprotein B-48

J. Kane, D. Hardman, 1986 .

Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes.

M. Malloy, J. Kane, M. Charles, 2011, Metabolism: clinical and experimental.

ABSENCE OF THE B-100 APOLIPOPROTEIN

M. Malloy, J. Kane, A. Hardman, 1981 .

New horizons in lipid management.

J. Kane, 2013, Journal of the American College of Cardiology.

Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.

J. Kane, V. Levin, A. Finn, 1980, The Journal of pharmacology and experimental therapeutics.

Characterization and quantitation of apolipoproteins A-I and E of normal and cholesterol-fed guinea pigs.

J. Kane, C. Fielding, R. Hamilton, 1982, Journal of lipid research.

Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL.

J. Lalouel, C. Pullinger, J. Kane, 1992, Journal of lipid research.

Determinants of kallikrein proteolysis of apolipoprotein B‐100 in human blood plasma

R. Havel, J. Kane, A. Gustafson, 1988, European journal of clinical investigation.

Temperature dependence of the optical activity of human serum low density lipoprotein. The role of lipids.

J. Kane, G. Chen, 1975, Biochemistry.

Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.

R. Mahley, R. Havel, J. Kane, 1981, The Journal of clinical investigation.

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

James T. Elder, A. Bowcock, D. Gladman, 2012, American journal of human genetics.

Medical management of hyperlipidemic states.

M. Malloy, J. Kane, 1994, Advances in internal medicine.

Multi-ethnic genome-wide association study for atrial fibrillation

Jay A. Montgomery, Nathan A. Bihlmeyer, Henry J. Lin, 2018, Nature Genetics.

Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy

K. Weisgraber, J. Kane, H. Pownall, 2011, Journal of Lipid Research.

Intravenous thyrotropin (TSH)-releasing hormone releases human TSH that is structurally different from basal TSH.

J. Kane, J. Magner, E. Chou, 1992, The Journal of clinical endocrinology and metabolism.

Structures of high-mannose and complex oligosaccharides of mouse TSH and free alpha-subunits after in vitro incubation of thyrotropic tissue with TRH.

J. Kane, J. Magner, Y. Miura, 1992, Endocrine research.

Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.

E. Steyerberg, E. Sijbrands, J. Kastelein, 2008, European Heart Journal.

Cholestasis: Lamellar Structure of the Abnormal Human Serum Lipoprotein

R. Havel, J. Kane, A. Blaurock, 1971, Science.

High-density lipoprotein metabolism and the human embryo.

R. Browne, J. Kane, M. Bloom, 2010, Human reproduction update.

The effect of ligand heterogeneity on the Scatchard plot. Particular relevance to lipoprotein binding analysis.

J. Kane, C. Mendel, V. Ličko, 1985, The Journal of biological chemistry.

Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma.

J P Kane, R J Havel, R. Havel, 1983, The Journal of clinical investigation.

Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia

J. Kane, Z. Randhawa, J. Ganesan, 1979, American journal of hematology.

Structural variation across 138,134 samples in the TOPMed consortium

Mark J. P. Chaisson, Nicholette D. Palmer, M. Fornage, 2023, bioRxiv.

Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Lack of Support for the Association Between GAD 2 Polymorphisms and Severe Human Obesity Permalink

P. Kwok, L. Pennacchio, W. Rief, 2005 .

Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia[S]

John F. Robinson, R. Hegele, A. McIntyre, 2019, Journal of Lipid Research.

Severe hypertriglyceridemia is primarily polygenic.

R. Hegele, A. McIntyre, H. Cao, 2019, Journal of clinical lipidology.

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia

P. Pajukanta, M. Malloy, C. Pullinger, 2007, Nature Genetics.

Mapping and characterization of structural variation in 17,795 human genomes

Eric S. Lander, Haley J. Abel, Yeting Zhang, 2020, Nature.

Functional variants of the HMGA1 gene and type 2 diabetes mellitus.

T. Mazza, A. Fusco, M. Malloy, 2011, JAMA.

Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia

Brent D. Davis, Allison A. Dilliott, R. Hegele, 2020, Arteriosclerosis, Thrombosis and Vascular Biology.

A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency.

G. Enns, B. Burton, J. Kane, 2015, The New England journal of medicine.

Exome Sequencing in Suspected Monogenic Dyslipidemias

S. Gabriel, M. Daly, J. Shendure, 2015, Circulation. Cardiovascular genetics.

Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders

M. Malloy, C. Pullinger, J. Kane, 2003, Expert review of cardiovascular therapy.

Evaluation of Langerhans' cells in the cervical epithelium of women with cervical intraepithelial neoplasia.

J. Kane, J. Connor, J. Goldberg, 1999, Gynecologic oncology.

Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens.

M J Malloy, J P Kane, R J Havel, 1990, JAMA.

Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype.

Celeste Eng, C. Eng, M. Malloy, 2002, The Journal of clinical investigation.

Ancestry-specific profiles of genetic determinants of severe hypertriglyceridemia.

Allison A. Dilliott, R. Hegele, A. McIntyre, 2020, Journal of clinical lipidology.

Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids.

Medha Kulkarni, Donna Drown, Bradley E Aouizerat, 2003, Journal of lipid research.

Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL.

P. Duchateau, K. Medzihradszky, K. Feingold, 2004, Atherosclerosis.

Apolipoprotein L-I is the trypanosome lytic factor of human serum

R. Brasseur, D. Nolan, L. Lins, 2003, Nature.

A Polymorphism in the Protease-Like Domain of Apolipoprotein(a) Is Associated With Severe Coronary Artery Disease

E. Topol, Curtis Noordhof, M. Koschinsky, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction.

M. Ezekowitz, B. Chaitman, D. Waters, 1998, The American journal of cardiology.

Binding of High Density Lipoprotein (HDL) and Discoidal Reconstituted HDL to the HDL Receptor Scavenger Receptor Class B Type I*

M. Krieger, J. Kane, Tong Liu, 2000, Journal of Biological Chemistry.

A multilocus genotyping assay for candidate markers of cardiovascular disease risk.

M J Malloy, J P Kane, G Siest, 1999, Genome research.

A Multilocus Genotyping Assay for Cardiovascular Disease

M J Malloy, J P Kane, G Siest, 1998, Clinical chemistry and laboratory medicine.

Apolipoprotein L, a New Human High Density Lipoprotein Apolipoprotein Expressed by the Pancreas

P. Duchateau, M. Malloy, C. Pullinger, 1997, The Journal of Biological Chemistry.

Improved separation of high-molecular-weight proteins by preparative sodium dodecyl sulfate--gel electrophoresis: application to apolipoprotein B.

J. Kane, D. Hardman, 1980, Analytical Biochemistry.

Scission of human apolipoprotein B-100 by kallikrein: characterization of the cleavage site.

J. Kane, J. Schilling, A. Gustafson, 1986, Biochemical and biophysical research communications.

The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles.

M. Koschinsky, C. Pullinger, J. Kane, 2010, Atherosclerosis.

Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels

A. Burlingame, J. Kane, O. Francone, 2011, Journal of Lipid Research.

Galanin Preproprotein Is Associated With Elevated Plasma Triglycerides

M. Laakso, J. Sinsheimer, C. Plaisier, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Human renin gene BglI dimorphism associated with hypertension in two independent populations

M. Malloy, J. Kane, P. Frossard, 1999, Clinical genetics.

Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.

R. Krauss, J. Kane, J. Purnell, 2012, The Journal of clinical endocrinology and metabolism.

Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender.

P. Duchateau, R. Redberg, M. Malloy, 1998, Journal of lipid research.

Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function.

P. Kwok, R. Deo, T. Wyss-Coray, 2014, JAMA neurology.

Emerging roles of HDL in immune function.

M. Malloy, J. Kane, K. Creasy, 2018, Current opinion in lipidology.

Octreotide changes serum thyrotropin (TSH) glycoisomer distribution as assessed by lectin chromatography in a TSH macroadenoma patient.

R. Smallridge, J. Kane, J. Magner, 1993, The Journal of clinical endocrinology and metabolism.

New molecular insights into CETP structure and function: a review

J. Kane, M. A. Charles, 2012, Journal of Lipid Research.

Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease.

M. Malloy, C. Pullinger, J. Kane, 2014, Heart rhythm.

Aggressive medical therapy for the prevention and treatment of coronary artery disease.

M. Malloy, J. Kane, 1997, Advances in internal medicine.

The effects of physical exercise on plasma prebeta-1 high-density lipoprotein.

C. Pullinger, J. Kane, D. Leaf, 2003, Metabolism: clinical and experimental.

Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia

P. Kwok, Dedeepya Vaka, R. Lifton, 2022, Journal of lipid research.

Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease.

Christian Zellner, Prakash Deedwania, L. Guey, 2011, The American journal of cardiology.

Metabolic abnormalities and coronary heart disease risk in human immunodeficiency virus-infected adults.

Kathryn A. Lee, C. Portillo, C. Pullinger, 2010, Metabolic syndrome and related disorders.

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

A. Windemuth, T. Holford, G. Ruaño, 2010, Pharmacogenomics.

GOSR2 Lys67Arg is associated with hypertension in whites.

Tamra E. Meyer, J. Pankow, E. Boerwinkle, 2009, American journal of hypertension.

Genetic variation in phospholipid transfer protein modulates lipoprotein profiles in hyperalphalipoproteinemia.

C. Eng, M. Malloy, C. Pullinger, 2008, Metabolism: clinical and experimental.

Elevated Baseline Triglyceride Levels Modulate Effects of HMGCoA Reductase Inhibitors on Plasma Lipoproteins

R. Drmanac, D. Gietzen, M. Malloy, 2001, Journal of cardiovascular pharmacology and therapeutics.

Lack of association of lipoprotein(a) levels with coronary calcium deposits in asymptomatic postmenopausal women.

M. Nishino, R. Redberg, M. Malloy, 2000, Journal of the American College of Cardiology.

Relation of Plasma Lipid and Apoprotein Levels to Progressive Intimal Hyperplasia After Arterial Endarterectomy

R. Stoney, R. Havel, J. Kane, 1992, Circulation.

Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients.

C. Clavel, I. Leclercq, C. Pullinger, 2014, Diabetes & metabolism.

Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene.

J P Kane, P. Duchateau, C. Eng, 2001, Journal of lipid research.

Splanchnic metabolism in healthy young men given clofibrate

R. Havel, J. Kane, B. Wolfe, 1970 .

Radiation inactivation of binding sites for high density lipoproteins in human fibroblast membranes.

J. Kane, E. Kempner, S. Kunitake, 1988, The Journal of biological chemistry.

Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins.

J P Kane, J. Kane, S. Kunitake, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of 17,576 Potentially Functional SNPs in Three Case–Control Studies of Myocardial Infarction

Mary J. Malloy, John P. Kane, J. Catanese, 2008, PloS one.

Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms.

P. Duchateau, C. Eng, C. Pullinger, 2000, Biochemical and biophysical research communications.

Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.

U. Hodoğlugil, M. Malloy, C. Pullinger, 2009, Metabolic syndrome and related disorders.

Apolipoprotein E e4 Allele Increases the Risk of Early Postoperative Delirium in Older Patients Undergoing Noncardiac Surgery

P. Kwok, L. Sands, C. Pullinger, 2007, Anesthesiology.

R. Havel, J. Kane, N. Phillips, 1983, Journal of lipid research.

Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression

J. Capone, M. Malloy, C. Pullinger, 2013, Journal of the American Heart Association.

Parotid secretory protein is an HDL-associated protein with anticandidal activity.

P. Duchateau, K. Medzihradszky, K. Feingold, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

Familial hypercholesterolaemia: cholesterol efflux and coronary disease

E. Sijbrands, B. Dahlbäck, C. Pullinger, 2016, European journal of clinical investigation.

WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.

T. Lehtimäki, R. Cantor, M. Laakso, 2008, American journal of human genetics.

Circular dichroic spectra of apolipoprotein E in model complexes and cholesterol-rich lipoproteins: lipid contribution.

J. Kane, R. L. Hamilton, G. Chen, 1984, Biochemistry.

Secondary structure and thermal behavior of trypsin-treated low-density lipoproteins from human serum, studied by circular dichroism.

J. Kane, M. Chapman, G. Chen, 1983, Biochimica et Biophysica Acta.

Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.

P. Kwok, J. Olgin, E. Vittinghoff, 2008, Heart rhythm.

New protein in human blood plasma, rich in proline, with lipid-binding properties.

R. Havel, J. Kane, L. Kotite, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1 Published, JLR Papers in Press, February 23, 2009.

Johnf . Thompson, C. Pullinger, J. Kane, 2009, Journal of Lipid Research.

Effect of diet composition on metabolic adaptations to hypocaloric nutrition: comparison of high carbohydrate and high fat isocaloric diets.

S. B. Lewis, J. Kane, J. Gerich, 1977, The American journal of clinical nutrition.

Five common gene variants identify elevated genetic risk for coronary heart disease

J. Pankow, E. Boerwinkle, S. Ellis, 2007, Genetics in Medicine.

CONDUCTION ANESTHESIA USING DIPHENHYDRAMINE HYDROCHLORIDE.

J. Kane, J. F. Welborn, 1964, Journal of the American Dental Association.

Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia.

M. Malloy, J. Kane, S. Kunitake, 1987, Annals of internal medicine.

Author response: An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish

P. Kwok, R. Deo, S. Coughlin, 2015 .

Cryo-electron microscopy of low density lipoprotein and reconstituted discoidal high density lipoprotein: imaging of the apolipoprotein moiety.

R. Krauss, C. Pullinger, J. Kane, 1997, Journal of lipid research.

Regulated expression of apolipoprotein E by human retinal pigment epithelial cells Published, JLR Papers in Press, November 1, 2003. DOI 10.1194/jlr.M300306-JLR200

A. Burlingame, J. Kane, R. Chalkley, 2004, Journal of Lipid Research.

Mechanisms of statin-induced myalgia assessed by physiogenomic associations.

A. Windemuth, T. Holford, G. Ruaño, 2011, Atherosclerosis.

Expression of Reverse Cholesterol Transport Proteins Atp- Binding Cassette A1 (abca1) and Scavenger Receptor Bi (sr-bi) in the Retina and Retinal Pigment Epithelium Nih Public Access Author Manuscript $watermark-text

M. Lavail, J. Duncan, J. Kane, 2022 .

High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture

J. Kane, D. Schwartz, B. Ishida, 2006, British Journal of Ophthalmology.

Human retinal pigment epithelial cells express scavenger receptors BI and BII.

J. Kane, D. Schwartz, K. Duncan, 2002, Biochemical and biophysical research communications.

Subunit heterogeneity in human serum beta lipoprotein.

R. Havel, J. Kane, E. Richards, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content.

S. Young, P. Hass, J. Scott, 1990, The Journal of biological chemistry.

The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds.

V. Schumaker, C. Packard, M. Malloy, 1999, Journal of lipid research.

Transfer of mouse anti-xenotropic virus neutralizing factor to human lipoproteins

J. Levy, J. Kane, D. Hardman, 1982, Journal of virology.

Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B.

J. Kane, J. Schilling, A. Protter, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry

J. Knowles, D. Rader, C. Ballantyne, 2023, Journal of the American Heart Association.

Safety findings from 3 trials of treatment with sebelipase alfa in children and adults with lysosomal acid lipase deficiency

B. Burton, J. Kane, A. Tylki-Szymańska, 2016 .

Secondary structure in very low density and intermediate density lipoproteins of human serum.

J. Kane, G. Chen, 1979, Journal of Lipid Research.

APOL1 Risk Variants Associate with the Prevalence of Stroke in African American Current and Past Smokers

M. Malloy, C. Pullinger, J. Kane, 2023, medRxiv.

Prebeta-1 HDL and coronary heart disease

M. Malloy, J. Kane, Mary J Malloy, 2012, Current opinion in lipidology.

Association between Regulator of G Protein Signaling 9–2 and Body Weight

R. Neve, S. Hamilton, W. Fairbrother, 2011, PloS one.

[30] Circular dichroism of lipoprotein lipids

J. Kane, G. Chen, 1986 .

Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia.

M. Malloy, C. Pullinger, J. Kane, 1993, Human Molecular Genetics.

The apolipoprotein C‐II variant apoC‐IILys19→Thr is not associated with dyslipidemia in an affected kindred

Robert V Farese, C. Pullinger, J. Kane, 1994, Clinical genetics.

Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients.

C. Clavel, M. Malloy, C. Pullinger, 2011, Diabetes & metabolism.

Treatment of hypercholesterolemia.

M. Malloy, J. Kane, 1982, The Medical clinics of North America.

Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: A report from the childhood cancer survivor study

M. Segal, L. Strong, K. Matthay, 2012, Pediatric blood & cancer.

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Andrew D. Johnson, Nicholette D. Palmer, Ansuman T. Satpathy, 2023, Nature.

Effect of thyroid hormone deficiency on glycosylation of rat TSH secreted in vitro.

J. Kane, M. Szabo, J. Magner, 1993, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Apolipoprotein A‐II Active or Passive Role in Familial Combined Hyperlipidemia

J. Kane, B. Aouizerat, 2003, Circulation research.

Treatment of hyperlipidemia.

M. Malloy, J. Kane, 1990, Annual Review of Medicine.

Isolation and characterization of apolipoprotein B-48.

J. Kane, D. Hardman, 1986, Methods in enzymology.

Hemoglobin Tak in a newborn Malay.

J. Kane, Z. Randhawa, L. Lie-injo, 1977, Hemoglobin.

Hb leiden‐β° thalassemia in a chinese with severe hemolytic anemia

J. Kane, Z. Randhawa, L. Lie-injo, 1977 .

DraI RFLP in the human apolipoprotein AI-CIII-AIV gene complex.

D. W. Lim, G. Assmann, M. Malloy, 1986, Nucleic acids research.

Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors

P. Kwok, M. Malloy, C. Pullinger, 2005, Human mutation.

Application of Machine Learning Ensemble Super Learner for analysis of the cytokines transported by high density lipoproteins (HDL) of smokers and nonsmokers

M. Malloy, J. Kane, K. Creasy, 2021, 2021 International Conference on Computational Science and Computational Intelligence (CSCI).

Gene Variants of VAMP8 and HNRPUL1 Are Associated With Early-Onset Myocardial Infarction

E. Topol, J. Catanese, S. Ellis, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Congenital absence of apolipoprotein E and neurological function-reply.

M. Malloy, J. Kane, 2014, JAMA neurology.

Lipoprotein disorders

M. Malloy, J. Kane, 2020, Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease.

Chapter 51 – Lipoprotein Disorders

M. Malloy, J. Kane, 2015 .

Measurement of prebeta-1 HDL in human plasma by an ultrafiltration-isotope dilution technique.

P. Duchateau, M. Malloy, J. Kane, 1997, Analytical biochemistry.

Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia.

E. Steyerberg, E. Sijbrands, J. Kastelein, 2009, Atherosclerosis.

Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population.

M. Malloy, C. Pullinger, J. Kane, 2014, Metabolic syndrome and related disorders.

STUDIES OF CARBOHYDRATE METABOLISM IN IDIOPATHIC HYPERTRIGLYCERIDEMIA.

C. Longcope, J. Kane, G. Grodsky, 1965, Metabolism: clinical and experimental.

Exploratory data analysis of hyperlipidemia on the Macintosh: Software tools for analysis of biochemical, clinical, and genetic variables in 1677 consecutive lipid clinic patients

Vikas Bhushan, Mary J. Malloy, Marguerite M. Engler, 1993, Journal of Medical Systems.

Machine Learning and Statistical Approaches for Classification of Risk of 1 Coronary Artery Disease using Plasma Cytokines . 2

M. Malloy, J. Kane, K. Creasy, 2020 .

Thermal behavior of cores of human serum triglyceride-rich lipoproteins: a study of induced circular dichroism of beta-carotene.

J. Kane, R. L. Hamilton, G. Chen, 1984, Biochemistry.

Apolipoprotein AII Active or Passive Role in Familial Combined Hyperlipidemia

J. Kane, B. Aouizerat, 2003 .

Structural domains of human apolipoprotein B-100. Differential accessibility to limited proteolysis of B-100 in low density and very low density lipoproteins.

J. Kane, J. Schilling, K. Lau, 1989, The Journal of biological chemistry.

Familial hypercholesterolemia in children: treatment with p-aminosalicylic acid.

M. Malloy, J. Kane, J. S. Rowe, 1978, Pediatrics.

Ricin and lentil lectin-affinity chromatography reveals oligosaccharide heterogeneity of thyrotropin secreted by 12 human pituitary tumors.

W. Young, R. Smallridge, J. Kane, 1992, Metabolism: clinical and experimental.

Binding of thyrotropin to lentil lectin is unchanged by thyrotropin-releasing hormone administration in three patients with thyrotropin-producing pituitary adenomas.

J. Kane, J. Magner, 1992, Endocrine Research.

Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism.

M. Malloy, J. Kane, M. Traber, 1992, Journal of lipid research.

Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens.

R. Havel, M. Malloy, J. Kane, 1990, JAMA.

Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3. Structure and genetics of an apolipoprotein E3 variant.

R. Mahley, K. Weisgraber, J. Kane, 1989, The Journal of clinical investigation.

Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects.

M. Malloy, J. Kane, A. Bener, 1999, Hypertension research : official journal of the Japanese Society of Hypertension.

Novel genetic markers for structural coronary artery disease, myocardial infarction, and familial combined hyperlipidemia: candidate and genome scans of functional SNPs

J. Catanese, Diane U. Leong, L. McAllister, 2004 .

Speciation of HDL.

J. Kane, 1986, Advances in experimental medicine and biology.

WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.

T. Lehtimäki, R. Cantor, M. Laakso, 2008, American journal of human genetics.

Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.

R. Havel, J. Kane, T. Bersot, 1983, The Journal of clinical investigation.

Multi-ethnic genome-wide association study for atrial fibrillation

Jay A. Montgomery, Brian R. Daniels, Blair H. Smith, 2018, Nature Genetics.

Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease.

M. Malloy, C. Pullinger, J. Kane, 2014, Heart rhythm.

Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.

P. Kwok, J. Olgin, E. Vittinghoff, 2008, Heart rhythm.

Control or Reversal of Atherosclerosis Through Therapy of Lipid Disorders

R. Havel, M. Malloy, J. Kane, 1984 .

Endocrine and metabolic alterations with food and water deprivation.

P. A. Lee, S. B. Lewis, J. Kane, 1977, The American journal of clinical nutrition.

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

James T. Elder, A. Bowcock, D. Gladman, 2012, American journal of human genetics.

Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib.

H. Brewer, S. Nissen, J. Kane, 2015, Journal of the American College of Cardiology.

Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.

E. Steyerberg, E. Sijbrands, J. Kastelein, 2008, European heart journal.

Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium

M. Lavail, J. Duncan, J. Kane, 2009, British Journal of Ophthalmology.

Pancreatic Alpha and Beta Cell Function in Familial Dysbetalipoproteinemia

R. Havel, J. Kane, Soeldner Js, 1980, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients.

C. Clavel, M. Malloy, C. Pullinger, 2011, Diabetes & metabolism.