P. Klepstad

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2013, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Long‐term health‐related quality of life and survival after cardiac surgery: A prospective study

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2018, The Journal of thoracic and cardiovascular surgery.

Is there a genetic cause for cancer cachexia? – a clinical validation study in 1797 patients

P M Fayers, P. Fayers, S. Kaasa, 2011, British Journal of Cancer.

The role of sex in health-related quality of life after cardiac surgery: a prospective study

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2008, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

Quality of Life in Patients With Advanced Cancer: Differential Association With Performance Status and Systemic Inflammatory Response.

M. Hjermstad, S. Kaasa, B. Laird, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Renal function and symptoms/adverse effects in opioid‐treated patients with cancer

S. Kaasa, P. Klepstad, O. Ekholm, 2015, Acta anaesthesiologica Scandinavica.

Quality of Life in Patients With Advanced Cancer : Differential Association With Performance Status and Systemic In fl ammatory Response

M. Hjermstad, S. Kaasa, B. Laird, 2016 .

The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer

P. Fayers, S. Kaasa, B. Laird, 2017, PloS one.

P. Romundstad, H. Myhre, P. Klepstad, 2005, Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing.

Intranasal midazolam: a comparison of two delivery devices in human volunteers

S. Kaasa, P. Klepstad, H. Tønnesen, 2006, The Journal of pharmacy and pharmacology.

Is there a genetic cause of appetite loss?—an explorative study in 1,853 cancer patients

P. Fayers, S. Kaasa, V. Baracos, 2012, Journal of cachexia, sarcopenia and muscle.

Direct transport versus interhospital transfer of patients with severe head injury in Norway

P. Klepstad, T. Skandsen, A. Vik, 2008, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain

M. Hjermstad, S. Kaasa, A. Caraceni, 2018, BMC Palliative Care.

Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial

John A Sanner, C. Callaway, R. Bellomo, 2022, Intensive Care Medicine.

Process of foregoing life‐sustaining treatment: a survey among Scandinavian intensivists

P. Klepstad, M. Hynninen, J. Petersson, 2008, Acta anaesthesiologica Scandinavica.

Pain Management in Mesothelioma

B. Laird, M. Fallon, P. Klepstad, 2015 .

Pharmacogenetics of Pain in Cancer

P. Klepstad, 2013 .

Genetic variability and opioid efficacy

P. Klepstad, 2007 .

Norwegian trauma care: a national cross-sectional survey of all hospitals involved in the management of major trauma patients

P. Klepstad, T. Kristiansen, O. Uleberg, 2014, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Content development for EUROPEAN GUIDELINES on the use of opioids for cancer pain: a systematic review and Expert Consensus Study.

S. Kaasa, L. Radbruch, A. Caraceni, 2010, Minerva anestesiologica.

From "Breakthrough" to "Episodic" Cancer Pain? A European Association for Palliative Care Research Network Expert Delphi Survey Toward a Common Terminology and Classification of Transient Cancer Pain Exacerbations.

S. Kaasa, M. Bennett, A. Caraceni, 2016, Journal of pain and symptom management.

Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: a randomized, placebo-controlled, double-blind trial.

P. Fayers, S. Kaasa, P. Klepstad, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

John A Sanner, C. Callaway, R. Bellomo, 2022, Intensive care medicine.

Acute kidney injury in intensive care patients: Incidence, time course, and risk factors

P. Klepstad, T. Nilsen, S. Mo, 2022, Acta anaesthesiologica Scandinavica.

Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy

M. Antonelli, J. Rello, S. Mehta, 2019, European Respiratory Journal.

Platelet transfusions and thrombocytopenia in intensive care units: Protocol for an international inception cohort study (PLOT‐ICU)

P. Póvoa, S. Chawla, V. Jalkanen, 2022, Acta anaesthesiologica Scandinavica.

An Update on Prevalence, Assessment, and Risk Factors for Sleep Disturbances in Patients with Advanced Cancer—Implications for Health Care Providers and Clinical Research

M. Hjermstad, P. Klepstad, K. H. Gjeilo, 2022, Cancers.

The systemic inflammatory response and its relationship to pain and other symptoms in advanced cancer.

P. Fayers, S. Kaasa, B. Laird, 2013, The oncologist.

Clinically significant drug–drug interactions involving opioid analgesics used for pain treatment in patients with cancer: a systematic review

D. Haugen, P. Klepstad, A. Kotlińska-Lemieszek, 2015, Drug design, development and therapy.

Inflammatory markers and radiotherapy response in patients with painful bone metastases.

S. Kaasa, C. Brunelli, P. Klepstad, 2022, Journal of pain and symptom management.

Long-term treatment with ketamine in a 12-year-old girl with severe neuropathic pain caused by a cervical spinal tumor.

S. Kaasa, P. Klepstad, P. Borchgrevink, 2001, Journal of pediatric hematology/oncology.

No pain, much gain

P. Klepstad, J. Rosland, 2011, Acta anaesthesiologica Scandinavica.

Relief of postural post dural puncture headache by an epidural blood patch 12 months after dural puncture

P. Klepstad, 1999, Acta anaesthesiologica Scandinavica.

[Biobank legislation stops research using critically ill patients].

P. Klepstad, O. Dale, 2005, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Opioid switching from morphine to methadone causes a minor but not clinically significant increase in QTc time: A prospective 9-month follow-up study.

S. Kaasa, P. Klepstad, O. Fredheim, 2006, Journal of pain and symptom management.

Changes in peripheral arterial blood pressure after resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic cardiac arrest patients

P. Klepstad, A. Krüger, E. Skjærseth, 2021, BMC Emergency Medicine.

Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

John A Sanner, C. Callaway, R. Bellomo, 2022, Critical Care.

Pain intensity and side effects during titration of morphine to cancer patients using a fixed schedule dose escalation.

S. Kaasa, P. Klepstad, P. Borchgrevink, 2000, Acta anaesthesiologica Scandinavica.

Start of oral morphine to cancer patients: effective serum morphine concentrations and contribution from morphine-6-glucuronide to the analgesia produced by morphine

S. Kaasa, P. Klepstad, P. Borchgrevink, 2000, European Journal of Clinical Pharmacology.

Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study

M. Hjermstad, S. Kaasa, P. Klepstad, 2022, Palliative medicine reports.

Psychometric properties of the Arabic version of EORTC QLQ-C15-PAL among cancer patients in Jordan

P. Klepstad, Hesham Yasin, K. Ammar, 2016, Supportive Care in Cancer.

Clinical Factors Associated With a Short Survival Time After Percutaneous Nephrostomy for Ureteric Obstruction in Cancer Patients: An Updated Model.

P. Klepstad, A. Innabi, Wa’el Tuqan, 2016, Journal of pain and symptom management.

A new version of the ischemic tourniquet pain test.

P. Klepstad, I. Oye, A. Maurset, 1991, Methods and findings in experimental and clinical pharmacology.

Effects on cancer patients' health-related quality of life after the start of morphine therapy.

S. Kaasa, P. Klepstad, P. Borchgrevink, 2000, Journal of pain and symptom management.

End‐of‐life care in intensive care units  Save lives that can be saved, offer the dying a peaceful and dignified death

P. Klepstad, S. Gisvold, 2003, Acta anaesthesiologica Scandinavica.

Assessments of patients' Experiences of breathlessness during a spontaneous breathing trial

P. Klepstad, K. Dybwik, U. Romild, 2015, Intensive Care Medicine Experimental.

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

S. Kaasa, F. Skorpen, P. Klepstad, 2002, European Journal of Clinical Pharmacology.

A controlled comparison between single doses of intravenous and intramuscular morphine with respect to analgesic effects and patient safety

P. Klepstad, O. Dale, J. Thoner, 2008, Acta anaesthesiologica Scandinavica.

Plasma exchange in the intensive care unit: a narrative review

M. Antonelli, J. Rello, S. Mehta, 2022, Intensive Care Medicine.

Immediate- or sustained-release morphine for dose finding during start of morphine to cancer patients: a randomized, double-blind trial

S. Kaasa, P. Klepstad, P. Borchgrevink, 2003, Pain.

Early pharmacokinetics of nasal fentanyl: is there a significant arterio-venous difference?

S. Kaasa, P. Klepstad, A. Angelsen, 2008, European Journal of Clinical Pharmacology.

Acute kidney injury in patients with COVID-19 in the intensive care unit: evaluation of risk factors and mortality in a national cohort

P. Klepstad, S. M. Aukland, F. Ghavidel, 2022, BMJ Open.

Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer—a double-blind, randomized placebo-controlled clinical multicenter phase IV trial

M. Hjermstad, S. Kaasa, P. Klepstad, 2022, Supportive Care in Cancer.

A cross-sectional study on prevalence of pain and breakthrough pain among an unselected group of outpatients in a tertiary cancer clinic

M. Hjermstad, S. Kaasa, C. Brunelli, 2014, Supportive Care in Cancer.

Opioid switching from oral slow release morphine to oral methadone may improve pain control in chronic non-malignant pain: a nine-month follow-up study

S. Kaasa, N. Landrø, P. Klepstad, 2006, Palliative medicine.

Evidence of a role for NMDA receptors in pain perception.

E. R. Moberg, P. Klepstad, I. Oye, 1990, European journal of pharmacology.

The evidence of neuraxial administration of analgesics for cancer‐related pain: a systematic review

P. Klepstad, S. Mercadante, G. Kurita, 2015, Acta anaesthesiologica Scandinavica.

Interventional Techniques for the Management of Cancer-Related Pain: Clinical and Critical Aspects

P. Klepstad, S. Mercadante, G. Kurita, 2019, Cancers.

Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations.

P. Klepstad, S. Mercadante, G. Kurita, 2015, Critical reviews in oncology/hematology.

Intensive care and traumatic brain injury after the introduction of a treatment protocol: a prospective study

P. Klepstad, T. Skandsen, A. Vik, 2013, Acta anaesthesiologica Scandinavica.

Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl

S. Kaasa, A. Somogyi, P. Klepstad, 2015, PloS one.

Health care providers underestimate symptom intensities of cancer patients: A multicenter European study

S. Kaasa, K. Bjordal, M. Sprangers, 2010, Health and quality of life outcomes.

Health care providers underestimate symptom intensities of cancer patients : A multicenter

S. Kaasa, K. Bjordal, M. Sprangers, 2010 .

Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC.

P. Stone, M. Maltoni, S. Kaasa, 2012, The Lancet. Oncology.

Starting Step III opioids for moderate to severe pain in cancer patients: Dose titration: A systematic review

S. Kaasa, P. Klepstad, P. Borchgrevink, 2011, Palliative medicine.

How to switch from morphine or oxycodone to methadone in cancer patients? a randomised clinical phase II trial.

S. Kaasa, P. Klepstad, O. Dale, 2011, European journal of cancer.

Management of opioid-induced nausea and vomiting in cancer patients: systematic review and evidence-based recommendations

S. Kaasa, P. Klepstad, E. A. Laugsand, 2011, Palliative medicine.

evidence-based recommendations Management of opioid-induced nausea and vomiting in cancer patients : systematic review and

S. Kaasa, P. Klepstad, 2011 .

Antibiotic Therapy in Integrated Oncology and Palliative Cancer Care: An Observational Study

P. Klepstad, E. T. Løhre, M. Thronæs, 2022, Cancers.

Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients

S. Kaasa, A. Caraceni, C. Brunelli, 2020, Scientific Reports.

Which domains should be included in a cancer pain classification system? Analyses of longitudinal data

S. Kaasa, G. Apolone, A. Caraceni, 2012, PAIN.

Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene

E. Bruera, S. Shete, S. Kaasa, 2007, PAIN.

Which variables are associated with pain intensity and treatment response in advanced cancer patients?— Implications for a future classification system for cancer pain

P. Fayers, S. Kaasa, G. Apolone, 2011, European journal of pain.

The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study

J. Ball, G. Velasco, P. Meybohm, 2019, Intensive Care Medicine.

Chronic postsurgical pain in patients 5 years after cardiac surgery: A prospective cohort study

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2017, European journal of pain.

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?

Miriam J. Johnson, S. Kaasa, A. Somogyi, 2015, BMJ Open.

Clinically Significant Drug-Drug Interactions Involving Medications Used for Symptom Control in Patients With Advanced Malignant Disease: A Systematic Review.

D. Haugen, P. Klepstad, A. Kotlińska-Lemieszek, 2019, Journal of pain and symptom management.

Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients

P. Klepstad, B. Haugen, O. Dale, 2013, Drug Metabolism and Disposition.

Genetic and Non-genetic Factors Associated With Constipation in Cancer Patients Receiving Opioids

P. Fayers, S. Kaasa, R. Sabatowski, 2015, Clinical and Translational Gastroenterology.

Biological pathways and genetic variables involved in pain

N. Pedersen, C. Cleeland, P. Klepstad, 2010, Quality of Life Research.

Erratum to: Biological pathways and genetic variables involved in pain

N. Pedersen, C. Cleeland, P. Klepstad, 2010, Quality of Life Research.

The 118 A > G polymorphism in the human µ‐opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease

S. Kaasa, F. Skorpen, P. Klepstad, 2004, Acta anaesthesiologica Scandinavica.

Tromboelastography: variability and relation to conventional coagulation test in non-bleeding intensive care unit patients

P. Klepstad, A. Espinosa, Jørgen Holli Halset, 2015, BMC Anesthesiology.

An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer

S. Kaasa, B. Laird, D. McMillan, 2019, Medicine.

Polymorphism in the μ-opioid receptor gene OPRM1 A118G —An example of the enigma of genetic variability behind chronic pain syndromes

P. Klepstad, 2014, Scandinavian journal of pain.

Risk Factors and Early Pharmacological Interventions to Prevent Chronic Postsurgical Pain Following Cardiac Surgery

P. Klepstad, K. H. Gjeilo, R. Stenseth, 2014, American Journal of Cardiovascular Drugs.

Trauma care in a combined rural and urban region: an observational study

P. Romundstad, P. Klepstad, T. Kristiansen, 2017, Acta anaesthesiologica Scandinavica.

A double-blind, randomized, crossover comparison between single-dose and double-dose immediate-release oral morphine at bedtime in cancer patients.

S. Kaasa, P. Klepstad, O. Dale, 2009, Journal of pain and symptom management.

Serum and cerebrospinal fluid morphine pharmacokinetics after single doses of intravenous and intramuscular morphine after hip replacement surgery

P. Klepstad, O. Dale, J. Thoner, 2007, European Journal of Clinical Pharmacology.

Concentrations of remifentanil, propofol, fentanyl, and midazolam during rewarming from therapeutic hypothermia

Ø. Salvesen, P. Klepstad, B. Haugen, 2014, Acta anaesthesiologica Scandinavica.

Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients

S. Kaasa, K. Bjordal, P. Klepstad, 2010, European Journal of Clinical Pharmacology.

Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2294 cancer pain patients

P. Fayers, M. Maltoni, S. Kaasa, 2011, PAIN.

A GTP cyclohydrolase 1 genetic variant delays cancer pain

A. Doehring, J. Lötsch, P. Klepstad, 2010, PAIN.

Clinical and genetic factors related to cancer-induced bone pain and bone pain relief.

M. Maltoni, O. Nanni, E. Scarpi, 2014, The oncologist.

Validation of the brief pain inventory in patients six months after cardiac surgery.

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2007, Journal of pain and symptom management.

Polypharmacy in patients with advanced cancer and pain: a European cross-sectional study of 2282 patients.

S. Kaasa, P. Klepstad, A. Kotlińska-Lemieszek, 2014, Journal of pain and symptom management.

Pain and pain treatments in European palliative care units. A cross sectional survey from the European Association for Palliative Care Research Network

S. Kaasa, F. De Conno, G. Hanks, 2005, Palliative medicine.

Ethical issues in intensive care – a survey among Scandinavian intensivists

P. Klepstad, M. Hynninen, J. Petersson, 2005, Acta anaesthesiologica Scandinavica.

Assessment of the time-dependent need for stay in a high dependency unit (HDU) after major surgery by using data from an anesthesia information management system

P. Klepstad, Pål Klepstad, Trond Nordseth, 2016, Journal of Clinical Monitoring and Computing.

Open Abdomen Treated with Negative Pressure Wound Therapy: Indications, Management and Survival

T. Dahl, P. Klepstad, A. Wibe, 2016, World Journal of Surgery.

Undertreatment of pain in the prehospital setting: a comparison between trauma patients and patients with chest pain

P. Klepstad, K. Bakkelund, S. Mellesmo, 2013, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

Expert conference on cancer pain assessment and classification—the need for international consensus: working proposals on international standards

J. Farrar, M. Hjermstad, S. Kaasa, 2011, BMJ Supportive & Palliative Care.

Evidence of peripheral nerve blocks for cancer-related pain: a systematic review.

P. Klepstad, S. Mercadante, G. Kurita, 2015, Minerva anestesiologica.

Quality measurement in physician-staffed emergency medical services: a systematic literature review

P. Klepstad, M. Rehn, O. Uleberg, 2018, International journal for quality in health care : journal of the International Society for Quality in Health Care.

The Norwegian brief pain inventory questionnaire: translation and validation in cancer pain patients.

S. Kaasa, C. Cleeland, T. Mendoza, 2002, Journal of pain and symptom management.

Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations

A. Caraceni, P. Klepstad, S. Mercadante, 2016, Acta oncologica.

COMBAT study – Computer based assessment and treatment – A clinical trial evaluating impact of a computerized clinical decision support tool on pain in cancer patients

Cinzia Brunelli, Stein Kaasa, S. Kaasa, 2017, Scandinavian journal of pain.

Classification of pain in cancer patients – a systematic literature review

M. Hjermstad, S. Kaasa, A. Caraceni, 2009, Palliative medicine.

Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study

S. Kaasa, K. Bjordal, P. Klepstad, 2011, European Journal of Clinical Pharmacology.

Severe head injury: control of physiological variables, organ failure and complications in the intensive care unit

P. Klepstad, T. Skandsen, A. Vik, 2007, Acta anaesthesiologica Scandinavica.

Predication of cancer patients' survival by pain interference items is not the same as evidence that pain intensity is a survival predictor.

S. Kaasa, P. Klepstad, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Intestinal injury in cardiac arrest is associated with multiple organ dysfunction: a prospective cohort study.

P. Klepstad, T. Ueland, A. Michelsen, 2023, Resuscitation.

The Use of Low-Dose Methadone as Add-On to Regular Opioid Therapy in Cancer-Related Pain at End of Life: A National Swedish Survey in Specialized Palliative Care.

P. Klepstad, P. Strang, S. Lundström, 2020, Journal of palliative medicine.

The Edmonton Classification System for Cancer Pain: comparison of pain classification features and pain intensity across diverse palliative care settings in eight countries.

M. Hjermstad, S. Kaasa, P. Klepstad, 2013, Journal of palliative medicine.

Routine drug monitoring of serum concentrations of morphine, morphine-3-glucuronide and morphine-6-glucuronide do not predict clinical observations in cancer patients

P. Fayers, S. Kaasa, P. Klepstad, 2003, Palliative medicine.

The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses

S. Kaasa, F. Skorpen, P. Klepstad, 2016, Acta anaesthesiologica Scandinavica.

Variable response to opioid treatment: any genetic predictors within sight?

S. Kaasa, F. Skorpen, P. Klepstad, 2008, Palliative medicine.

Genetic variation in the Catechol-O-Methyltransferase (COMT) gene and morphine requirements in cancer patients with pain

S. Kaasa, F. Skorpen, P. Klepstad, 2008, Molecular pain.

Biological pathways, candidate genes, and molecular markers associated with quality-of-life domains: an update

J. Singh, J. Sloan, M. Sprangers, 2014, Quality of Life Research.

Establishing a Longitudinal Opioid Pharmacogenomic Registry for Cancer Patients: Feasibility and Acceptability.

P. Gibbs, A. Somogyi, P. Klepstad, 2022, Journal of palliative medicine.

Human Genetic Variability Contributes to Postoperative Morphine Consumption.

M. Zorzetto, V. Napolioni, P. Klepstad, 2016, The journal of pain : official journal of the American Pain Society.

The breath of life. Patients' experiences of breathing during and after mechanical ventilation.

P. Klepstad, H. Dahlberg, H. S. Haugdahl, 2017, Intensive & critical care nursing.

Underestimation of Patient Breathlessness by Nurses and Physicians during a Spontaneous Breathing Trial.

P. Klepstad, K. Dybwik, U. Romild, 2015, American journal of respiratory and critical care medicine.

Pain Intensity Factors Changing Breakthrough Pain Prevalence in Patients with Advanced Cancer: A Secondary Analysis of a Cross-Sectional Observational International Study

M. Hjermstad, S. Kaasa, C. Brunelli, 2018, Pain and Therapy.

Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial

P. Fayers, M. Hjermstad, S. Kaasa, 2018, Trials.

Can cancer patients assess the influence of pain on functions? A randomised, controlled study of the pain interference items in the Brief Pain Inventory

S. Kaasa, P. Klepstad, Guri Stenseth, 2007, BMC palliative care.

Cancer patients' barriers to pain management and psychometric properties of the Norwegian version of the Barriers Questionnaire II.

Christine Miaskowski, P. Klepstad, C. Miaskowski, 2009, Scandinavian journal of caring sciences.

Which factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analyses

M. Hjermstad, S. Kaasa, M. Bennett, 2018, Supportive Care in Cancer.

Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients

S. Kaasa, A. Caraceni, C. Brunelli, 2020, Scientific Reports.

Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study

S. Kaasa, K. Bjordal, P. Klepstad, 2011, European Journal of Clinical Pharmacology.

Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids.

P. Fayers, M. Maltoni, S. Kaasa, 2011, European journal of cancer.

Multiple Loci Modulate Opioid Therapy Response for Cancer Pain

Cinzia Brunelli, Augusto Caraceni, Stein Kaasa, 2011, Clinical Cancer Research.

Prevalence and predictors of cognitive dysfunction in opioid-treated patients with cancer: a multinational study.

S. Kaasa, P. Klepstad, J. Loge, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

REBOARREST, resuscitative endovascular balloon occlusion of the aorta in non-traumatic out-of-hospital cardiac arrest: a study protocol for a randomised, parallel group, clinical multicentre trial

P. Klepstad, M. Rehn, Jostein Dale, 2021, Trials.

Cognitive dysfunction and health‐related quality of life after a cardiac arrest and therapeutic hypothermia

P. Klepstad, H. Flaatten, T. Wentzel‐Larsen, 2010, Acta anaesthesiologica Scandinavica.

Antiplatelet effect of clopidogrel is reduced in patients treated with therapeutic hypothermia after cardiac arrest.

P. Klepstad, B. Haugen, O. Dale, 2010, Resuscitation.

Which mini-mental state exam items can be used to screen for delirium and cognitive impairment?

P. Fayers, M. Hjermstad, S. Kaasa, 2005, Journal of pain and symptom management.

Response to letter by Mercadante

S. Kaasa, G. Apolone, A. Caraceni, 2012, PAIN®.

Confusion with cerebral perfusion pressure in a literature review of current guidelines and survey of clinical practise

P. Klepstad, O. Solheim, V. Rao, 2013, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Clinical predictors for analgesic response to radiotherapy in patients with painful bone metastases.

S. Kaasa, C. Brunelli, P. Klepstad, 2021, Journal of pain and symptom management.

Breakthrough cancer pain in 2020.

P. Klepstad, E. T. Løhre, M. Thronæs, 2020, Current opinion in supportive and palliative care.

Chronic pain after cardiac surgery: a prospective study

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2010, Acta anaesthesiologica Scandinavica.

Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study

S. Kaasa, A. Somogyi, P. Klepstad, 2014, Pharmacogenetics and genomics.

Influences on serum concentrations of morphine, M6G and M3G during routine clinical drug monitoring: A prospective survey in 300 adult cancer patients

S. Kaasa, P. Klepstad, O. Dale, 2003, Acta anaesthesiologica Scandinavica.

Genetic findings related to pain and analgesics-why are they so inconsistent?

F. Skorpen, P. Klepstad, 2016, Pain.

The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: a prospective cohort study.

P. Klepstad, T. Ueland, A. Michelsen, 2021, Resuscitation.

Influenza and associated co-infections in critically ill immunosuppressed patients

M. Antonelli, J. Rello, S. Mehta, 2019, Critical Care.

[Genetic variation-- important for the clinical effect of opioids?].

S. Kaasa, F. Skorpen, P. Klepstad, 2005, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Sleep quality with WHO Step III opioid use for cancer pain

P. Fayers, M. Hjermstad, S. Kaasa, 2018, BMJ Supportive & Palliative Care.

Confirming neuropathic pain in cancer patients: Applying the NeuPSIG grading system in clinical practice and clinical research

Roman Rolke, Marie Fallon, Michael I. Bennett, 2014, PAIN®.

Use of National Early Warning Score for observation for increased risk for clinical deterioration during post-ICU care at a surgical ward

P. Klepstad, T. Nordseth, N. Sikora, 2019, Therapeutics and clinical risk management.

The importance and pitfalls of correlational science in palliative care research

S. Kaasa, P. Klepstad, 2012, Current opinion in supportive and palliative care.

Improved Pain Control in Terminally Ill Cancer Patients by Introducing Low-Dose Oral Methadone in Addition to Ongoing Opioid Treatment.

P. Klepstad, Sara Runesdotter, P. Strang, 2017, Journal of palliative medicine.

Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study

P. Meybohm, D. D. de Lange, R. Fumagalli, 2020, Annals of Intensive Care.

Resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest: evaluation of an educational programme

P. Klepstad, A. Krüger, E. Søvik, 2019, BMJ Open.

Recovery patterns and health-related quality of life in older patients undergoing cardiac surgery: a prospective study

S. Lydersen, P. Klepstad, K. H. Gjeilo, 2012, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

Intensity and treatment of symptoms in 3,030 palliative care patients: a cross-sectional survey of the EAPC Research Network.

S. Kaasa, F. De Conno, G. Hanks, 2018, Journal of opioid management.

Interventions and symptom relief in hospital palliative cancer care: results from a prospective longitudinal study

P. Klepstad, E. Brenne, E. T. Løhre, 2021, Supportive Care in Cancer.

Inadequate symptom control in advanced cancer patients across Europe

S. Kaasa, P. Klepstad, Gunnhild Jakobsen, 2010, Supportive Care in Cancer.

Genetic variability of pain – A patient focused end-point

F. Skorpen, P. Klepstad, 2016, Scandinavian journal of pain.

University of Southern Denmark Genetic variation and cognitive dysfunction in opioid-treated patients with cancer

S. Kaasa, F. Skorpen, P. Klepstad, 2016 .

Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain

S. Kaasa, A. Caraceni, F. Skorpen, 2013, Pharmacogenetics and genomics.

Evidence-based guidelines for the use of opioid analgesics in the treatment of cancer pain: The 2011 EAPC Recommendations.

P. Stone, M. Maltoni, S. Kaasa, 2012 .

The Brief Pain Inventory: Pain's Interference With Functions Is Different in Cancer Pain Compared With Noncancer Chronic Pain

S. Lydersen, S. Kaasa, P. Klepstad, 2008, The Clinical journal of pain.

Further restrictions for ICU research

P. Klepstad, O. Dale, 2005, Intensive Care Medicine.

Propofol and remifentanil versus midazolam and fentanyl for sedation during therapeutic hypothermia after cardiac arrest: a randomised trial

S. Lydersen, P. Klepstad, B. Haugen, 2012, Intensive Care Medicine.

S. Lydersen, P. Klepstad, A. Wahba, 2006, Scandinavian cardiovascular journal : SCJ.

The characteristics of physical activity and gait in patients receiving radiotherapy in cancer induced bone pain.

S. Kaasa, G. Murray, B. Laird, 2014, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

BMC Clinical Pharmacology BioMed Central

S. Kaasa, P. Klepstad, P. Borchgrevink, 2004 .

Pain management index (PMI)—does it reflect cancer patients’ wish for focus on pain?

S. Kaasa, C. Brunelli, P. Klepstad, 2019, Supportive Care in Cancer.

Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy

P. Fayers, M. Hjermstad, S. Kaasa, 2019, Supportive Care in Cancer.

Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

K. Goffin, G. Velasco, D. D. de Lange, 2021, Critical Care.

Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS)

P. Fayers, S. Kaasa, F. Skorpen, 2012, BMJ Supportive & Palliative Care.

Self-reports are not related to objective assessments of cognitive function and sedation in patients with cancer pain admitted to a palliative care unit

S. Kaasa, P. Klepstad, P. Borchgrevink, 2002, Palliative medicine.

Common sense won: engagement from experts repealed Norwegian restrictions for ICU research

P. Klepstad, A. Guttormsen, O. Dale, 2007, Intensive Care Medicine.

Characteristics of circulatory failure after out-of-hospital cardiac arrest: a prospective cohort study

P. Klepstad, K. Bjørnstad, T. Nordseth, 2022, Open Heart.

Is oxycodone efficacy reflected in serum concentrations? A multicenter, cross-sectional study in 456 adult cancer patients.

S. Kaasa, K. Bjordal, P. Klepstad, 2012, Journal of pain and symptom management.

Opioids in pain management of mesothelioma and lung cancer patients

S. Kaasa, P. Klepstad, K. Syrjänen, 2013, Acta oncologica.

Management and outcomes in critically ill nonagenarian versus octogenarian patients

J. Ball, G. Velasco, P. Meybohm, 2021, BMC Geriatrics.

Improper monitoring and deviations from physiologic treatment goals in patients with brain injury in the early phases of emergency care

P. Klepstad, O. Uleberg, Siri Andersen, 2020, Journal of Clinical Monitoring and Computing.

Tapentadol versus oxycodone for postoperative pain treatment the first 7 days after total knee arthroplasty: a randomized clinical trial.

P. Klepstad, T. Wik, J. Klaksvik, 2020, Pain.

Authors' Reply to Davies et al.

S. Kaasa, A. Caraceni, C. Brunelli, 2016, Journal of Pain and Symptom Management.

Continuous subcutaneous infusion for pain control in dying patients: experiences from a tertiary palliative care center

P. Klepstad, P. Strang, S. Lundström, 2020, BMC Palliative Care.

The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial

P. Fayers, M. Hjermstad, S. Kaasa, 2020, Supportive Care in Cancer.

Reply to a. Molfino et Al.

S. Kaasa, P. Klepstad, N. Aass, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[Intensive care of patients with acute liver failure].

P. Klepstad, L. Ytrebø, 2010, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Population‐based analysis of the impact of trauma on longer‐term functional outcomes

P. Romundstad, P. Klepstad, T. Kristiansen, 2018, The British journal of surgery.

Feasibility of Pre‐Hospital Resuscitative Endovascular Balloon Occlusion of the Aorta in Non‐Traumatic Out‐of‐Hospital Cardiac Arrest

P. Klepstad, A. Krüger, E. Søvik, 2019, Journal of the American Heart Association.

Four years' treatment with ketamine and a trial of dextromethorphan in a patient with severe post‐herpetic neuralgia

P. Klepstad, P. Borchgrevink, 1997, Acta anaesthesiologica Scandinavica.

Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study

P. Klepstad, K. Bjørnstad, T. Nordseth, 2021, BMC Anesthesiology.

Editorial: Early palliative care for cancer patients

M. Maltoni, A. Caraceni, P. Klepstad, 2023, Frontiers in Oncology.

Effectiveness of Opioid Switching in Advanced Cancer Pain: A Prospective Observational Cohort Study

A. Somogyi, P. Klepstad, B. Le, 2023, Cancers.

Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects

S. Kaasa, P. Klepstad, O. Fredheim, 2007, European journal of pain.

Interrater reliability of Nursing Activities Score among Intensive Care Unit health professionals.

P. Klepstad, S. Stafseth, Marit Stuedahl, 2015, Revista da Escola de Enfermagem da U S P.

[Therapeutic hypothermia--pharmacology and pathophysiology].

K. Sunde, P. Klepstad, O. Dale, 2007, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Long-term survival and quality of life after intensive care for patients 80 years of age or older

P. Klepstad, H. Flaatten, U. Romild, 2015, Annals of Intensive Care.

[71-year old man with severe circulatory collapse following heart arrest].

A. W. Carlsen, P. Klepstad, B. Haugen, 2010, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study

P. Klepstad, J. Damås, K. Bjørnstad, 2018, JMIR research protocols.

Long-Term Outcomes After ICU Admission Triage in Octogenarians

P. Klepstad, H. Flaatten, T. Follestad, 2017, Critical care medicine.

Interviews with patients with advanced cancer—another step towards an international cancer pain classification system

M. Hjermstad, S. Kaasa, P. Klepstad, 2012, Supportive Care in Cancer.

A GTP cyclohydrolase 1 genetic variant delays cancer pain

A. Doehring, J. Lötsch, P. Klepstad, 2010, PAIN.

Day-to-day variations during clinical drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study

P. Klepstad, Jorunn Moen, Stein Kaasa, 2004, BMC clinical pharmacology.

Respiratory Mechanics and Outcomes in Immunocompromised patients with ARDS - A secondary analysis of the EFRAIM study.

M. Antonelli, J. Rello, S. Mehta, 2020, Chest.

Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning

F. Skorpen, A. Drewes, A. Olesen, 2018, BMC Research Notes.

Genetic variation and cognitive dysfunction in opioid‐treated patients with cancer

F. Skorpen, P. Klepstad, G. Kurita, 2016, Brain and behavior.

Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer

Joseph A. Bulbulia, Q. Atkinson, P. Klepstad, 2015 .

Reply to S. McMorn et al

S. Kaasa, P. Klepstad, J. Loge, 2011 .

Consultant or Advisory Role: None Stock Ownership: Stephen McMorn, Endo Pharmaceuticals Honoraria: None Research Funding: None Expert Testimony: None Other Remuneration: None

S. Kaasa, P. Klepstad, O. Ekholm, 2011 .

Genetic clustering of European cancer patients indicates that opioid-mediated pain relief is independent of ancestry

S. Kaasa, T. Dragani, F. Skorpen, 2011, The Pharmacogenomics Journal.

review Starting Step III opioids for moderate to severe pain in cancer patients: Dose titration: A systematic

S. Kaasa, P. Klepstad, P. Borchgrevink, 2011 .

Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study

S. Kaasa, A. Somogyi, P. Klepstad, 2014, Pharmacogenetics and genomics.

Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases

P. Klepstad, E. T. Løhre, T. Solheim, 2023, Pain and Therapy.

The European Union–not united in opioid use

S. Kaasa, P. Klepstad, O. Dale, 2005, Palliative medicine.

Abstract 357: Resuscitative Balloon Occlusion of the Aorta in Non-Traumatic out of Hospital Cardiac Arrest - Evaluation of an Educational Program

P. Klepstad, A. Krüger, E. Søvik, 2018, Circulation.

Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

P. Klepstad, K. Puxty, É. Azoulay, 2023, Intensive Care Medicine.

Short-term effects of endotracheal suctioning in post-cardiac arrest patients: A prospective observational cohort study

P. Klepstad, T. Nordseth, Halvor Langeland, 2022, Resuscitation plus.

Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: an observational study

Myung Ah Lee, P. Klepstad, H. Ahn, 2015, BMC Palliative Care.

Polymorphism in the μ-opioid receptor gene OPRM1 A118G —An example of the enigma of genetic variability behind chronic pain syndromes

P. Klepstad, 2014, Scandinavian journal of pain.

S. Kaasa, M. Bennett, A. Caraceni, 2016, Journal of pain and symptom management.

Frailty and survival in elderly intensive care patients in Norway

P. Klepstad, H. Flaatten, Ø. Haaland, 2021, Acta anaesthesiologica Scandinavica.

Genetic variability of pain – A patient focused end-point

F. Skorpen, P. Klepstad, 2016, Scandinavian journal of pain.