A. Groom

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Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.

K. Luzzi, I. Macdonald, E. Schmidt, 1998, The American journal of pathology.

Early interactions of cancer cells with the microvasculature in mouse liver and muscle during hematogenous metastasis: videomicroscopic analysis

I. Macdonald, E. Schmidt, V. Morris, 1993, Clinical & Experimental Metastasis.

Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis.

G. Naumov, R. Hoffman, I. Macdonald, 1999, Journal of cell science.

Muscle capillary-to-fiber perimeter ratio: morphometry.

C. Ellis, I. Macdonald, A. Groom, 1991, The American journal of physiology.

Metastasis: Dissemination and growth of cancer cells in metastatic sites

I. Macdonald, A. Chambers, A. Groom, 2002, Nature Reviews Cancer.

The Krogh cylinder geometry is not appropriate for modelling O2 transport in contracted skeletal muscle.

C. Ellis, A. Groom, R. Potter, 1983, Advances in experimental medicine and biology.

Capillary diameter and geometry in cardiac and skeletal muscle studied by means of corrosion casts.

A. Groom, R. Potter, A C Groom, 1983, Microvascular research.

Microcirculatory pathways and blood flow in spleen: new insights from washout kinetics, corrosion casts, and quantitative intravital videomicroscopy.

I. Macdonald, E. Schmidt, A. Groom, 1991, Scanning microscopy.

The flow of red cell suspensions through narrow tubes - The /extracorporeal/ determination of the difference in mean velocities of red cells and their suspending phase

A. Groom, R. French, S. Rowlands, 1965 .

Heterogeneity of capillary diameters in skeletal muscle of the frog.

C. Ellis, A. Groom, K. Tyml, 1983, Microvascular research.

Geometrical distribution of capillaries in mammalian striated muscle.

A. Groom, M. Plyley, 1975, The American journal of physiology.

Variability of three-dimensional high-frequency ultrasound measurements of small tumor volumes

A. Fenster, I. Macdonald, A. Chambers, 2004, IEEE Ultrasonics Symposium, 2004.

Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases

A Fenster, A. Fenster, I. Macdonald, 2006, Physics in medicine and biology.

Spontaneous cyclic contractions of the capillary wall in vivo, impeding red cell flow: a quantitative analysis. Evidence for endothelial contractility.

I. Macdonald, E. Schmidt, A. Groom, 1988, Microvascular research.

Microcirculation in mouse spleen (nonsinusal) studied by means of corrosion casts

I. Macdonald, E. Schmidt, A. Groom, 1985, Journal of morphology.

Scanning and transmission electron microscopy and high resolution intravital video‐microscopy of capillaries in the mouse exocrine pancreas, with special emphasis on endothelial cells

I. Macdonald, E. Schmidt, A. Groom, 1993, The Anatomical record.

Organization and Flow in the Liver Microcirculation1

E. Schmidt, A. Groom, P. J. Macphee, 1993 .

Geometry of the capillary network in skeletal muscle.

A. Groom, M. Plyley, G. Sutherland, 1976, Microvascular research.

Evidence for Kupffer cell migration along liver sinusoids, from high-resolution in vivo microscopy.

E. Schmidt, A. Groom, P. J. Macphee, 1992, The American journal of physiology.

pH environmental of red cells in the spleen.

A. Groom, M. Levesque, 1976, The American journal of physiology.

Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis.

R. Khokha, I. Macdonald, E. Schmidt, 1995, Experimental cell research.

Blood Vascular Casting in Cardiac and Skeletal Muscle

A. Groom, R. Potter, 1992 .

Capillary configuration and fiber shortening in muscles of the rat hindlimb: correlation between corrosion casts and stereological measurements.

C. Ellis, A. Groom, R. Potter, 1988, Microvascular research.

Blood Flow in Skeletal Muscle

H. Weiss, A. K. Sinha, B. Zweifach, 1976 .

Microcirculatory pathways in normal human spleen, demonstrated by scanning electron microscopy of corrosion casts.

I. Macdonald, E. Schmidt, A. Groom, 1988, The American journal of anatomy.

Kinetics of red blood cell passage through interendothelial slits into venous sinuses in rat spleen, analyzed by in vivo microscopy.

I. Macdonald, E. Schmidt, A. Groom, 1987, Microvascular research.

Microcirculation in rat spleen (sinusal), studied by means of corrosion casts, with particular reference to the intermediate pathways

I. Macdonald, E. Schmidt, A. Groom, 1985, Journal of morphology.

Circulatory pathways in the sinusal spleen of the dog, studied by scanning electron microscopy of microcorrosion casts

I. Macdonald, E. Schmidt, A. Groom, 1983, Journal of morphology.

The intermediate circulation in the nonsinusal spleen of the cat, studied by scanning electron microscopy of microcorrosion casts

I. Macdonald, E. Schmidt, A. Groom, 1983, Journal of morphology.

Some circulatory responses to haemorrhage in the cat: a critical level of blood volume for the onset of hypotension.

A. Groom, S. Rowlands, H. Thomas, 1965, Quarterly journal of experimental physiology and cognate medical sciences.

of the Capillary Vascular Network

A. Groom, M. Plyley, 1976 .

Luminal morphology of small arterial vessels in the contracted spleen, studied by scanning electron microscopy of microcorrosion casts

I. Macdonald, E. Schmidt, A. Groom, 2004, Cell and Tissue Research.

Temporal distributions of red cell supply rate to individual capillaries of resting skeletal muscle, in frog and rat.

C. Ellis, A. Groom, R. Potter, 1990, International journal of microcirculation, clinical and experimental.

Microvascular evidence for a transition zone around a chronic myocardial infarct in the rat.

A. Groom, K. Przyklenk, 1983, Canadian journal of physiology and pharmacology.

Capillary lengths and anastomoses in rat hindlimb muscles, studied by Aquablak perfusion during rest versus exercise.

A. Groom, R. Potter, S. Houghton, 1989, Advances in experimental medicine and biology.

The design of wedge filters for X-ray therapy.

A. Groom, 1951, The British journal of radiology.

Splenic Microcirculatory Blood Flow and Function with Respect to Red Blood Cells

I. Macdonald, E. Schmidt, A. Groom, 2002 .

Direct arteriovenous connections and the intermediate circulation in dog spleen, studied by scanning electron microscopy of microcorrosion casts

I. Macdonald, E. Schmidt, A. Groom, 2004, Cell and Tissue Research.

Comparative aspects of splenic microcirculatory pathways in mammals: the region bordering the white pulp.

I. Macdonald, E. Schmidt, A. Groom, 1993, Scanning microscopy.

Fate of melanoma cells entering the microcirculation: over 80% survive and extravasate.

R. Khokha, K. Luzzi, I. Macdonald, 1995, Cancer research.

Activated ras regulates the proliferation/apoptosis balance and early survival of developing micrometastases.

I. Macdonald, A. Chambers, A. Groom, 2002, Cancer research.

Survive and Extravasate Fate of Melanoma Cells Entering the Microcirculation : Over 80 % Updated

R. Khokha, K. Luzzi, I. Macdonald, 2006 .

Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy.

G. Naumov, I. Macdonald, N. Kerkvliet, 2002, Cancer research.

Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency.

I. Macdonald, E. Schmidt, N. Kerkvliet, 2000, Cancer research.

Intravital videomicroscopy of the chorioallantoic microcirculation: a model system for studying metastasis.

I. Macdonald, E. Schmidt, V. Morris, 1992, Microvascular research.

Sequential steps in hematogenous metastasis of cancer cells studied by in vivo videomicroscopy.

I. Macdonald, E. Schmidt, V. Morris, 1997, Invasion & metastasis.

Cancer spread and micrometastasis development: Quantitative approaches for in vivo models

I. Macdonald, A. Chambers, A. Groom, 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

Storage of blood cells in spleen of the cat.

A. Groom, S. Song, S. H. Song, 1971, The American journal of physiology.

Inhibition of angiogenesis in liver metastases by carboxyamidotriazole (CAI)

Kathryn E. Marshall, E. Kohn, K. Luzzi, 2004, Angiogenesis.

Cardiac output in the cat; a comparison between the Fick method and a radioactive indicator dilution method.

K. W. Cross, A. Groom, S. Rowlands, 1957, The Journal of physiology.

The effect of lowering the pulse pressure in the carotid arteries on the cardiac output in the cat.

A. Groom, B. Lofving, S. Rowlands, 1962, Acta physiologica Scandinavica.

Fourier transform analysis of periodic variations of red cell velocity in capillaries of resting skeletal muscle in frogs.

A. Groom, K. Tyml, 1980, Microvascular research.

Immature and abnormal erythrocytes present in the normal, healthy spleen.

A. Groom, S. Song, 2009, Scandinavian journal of haematology.

The distribution of red cells in the spleen.

A. Groom, S. Song, S. H. Song, 1971, Canadian journal of physiology and pharmacology.

The Microcirculatory Society Eugene M. Landis award lecture. Microcirculation of the spleen: new concepts, new challenges.

A. Groom, A C Groom, 1987, Microvascular research.

Sequestration and possible maturation of reticulocytes in the normal spleen.

A. Groom, S. Song, S. H. Song, 1972, Canadian journal of physiology and pharmacology.

Luminal constrictions due to endothelial cells in capillaries of mouse exocrine pancreas.

I. Macdonald, E. Schmidt, A. Groom, 1995, Microvascular research.

Changes in splenic microcirculatory pathways in chronic idiopathic thrombocytopenic purpura.

I. Macdonald, E. Schmidt, A. Groom, 1991, Blood.

The Cardiac Output and Blood Volume of the Anaesthetized Cat

A. Groom, S. Rowlands, 1958, Physics in medicine and biology.

Solitary cancer cells as a possible source of tumour dormancy?

G. Naumov, I. Macdonald, A. Chambers, 2001, Seminars in cancer biology.

Scanning electron microscope study of the splenic red pulp in relation to the sequestration of immature and abnormal red cells

A. Groom, A. C. Groom, S. Song, 1974, Journal of morphology.

Intermittence of blood flow in liver sinusoids, studied by high-resolution in vivo microscopy.

E. Schmidt, A. Groom, P. J. Macphee, 1995, The American journal of physiology.

Critical steps in hematogenous metastasis: an overview.

G. Naumov, I. Macdonald, A. Chambers, 2001, Surgical oncology clinics of North America.

Clinical targets for anti-metastasis therapy.

I. Macdonald, E. Schmidt, V. Morris, 2000, Advances in cancer research.

Integrin VLA-2 (a2ÃŸi)Function in Postextravasation Movement of Human Rhabdomyosarcoma RD Cells in the Liver1

Christoph, Dolores, I. Macdonald, 2006 .

Integrin VLA-2 (alpha2beta1) function in postextravasation movement of human rhabdomyosarcoma RD cells in the liver.

I. Macdonald, E. Schmidt, V. Morris, 1996, Cancer research.

Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth

I. Macdonald, E. Schmidt, V. Morris, 1994, Clinical & Experimental Metastasis.

Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

R. Khokha, I. Macdonald, E. Schmidt, 1994, Cancer research.

The difference in circulation times of plasma and corpuscles in the cat

A. Groom, S. Rowlands, W. B. Morris, 1957, The Journal of physiology.

Ineffectiveness of Doxorubicin Treatment on Solitary Dormant Mammary Carcinoma Cells or Late-developing Metastases

Jason L. Townson, G. Naumov, V. Bramwell, 2003, Breast Cancer Research and Treatment.

Preclinical Assessment of Anti-cancer Therapeutic Strategies using in vivo Videomicroscopy

I. Macdonald, E. Schmidt, V. Morris, 1998, Cancer and Metastasis Reviews.

Heterogeneity of red blood cell perfusion in capillary networks supplied by a single arteriole in resting skeletal muscle.

C. Ellis, A. Groom, S. M. Wrigley, 1994, Circulation research.

Three-dimensional high-frequency ultrasound imaging for longitudinal evaluation of liver metastases in preclinical models.

Aaron Fenster, James C Lacefield, A. Fenster, 2005, Cancer research.

Microcirculatory changes in livers of mice infected with murine hepatitis virus. Evidence from microcorrosion casts and measurements of red cell velocity.

E. Schmidt, A. Groom, P. Keown, 1988, Microvascular research.

Interactions of leukocytes with vessel walls and with other blood cells, studied by high-resolution intravital videomicroscopy of spleen.

I. Macdonald, E. Schmidt, A. Groom, 1990, Microvascular research.

Time-Course Characterization of the Computed Tomography Contrast Enhancement of an Iodinated Blood-Pool Contrast Agent in Mice Using a Volumetric Flat-Panel Equipped Computed Tomography Scanner

David W Holdsworth, Nancy L Ford, D. Holdsworth, 2006, Investigative radiology.

Washout kinetics of red cells and plasma from the spleen.

A. Groom, M. Levesque, 1976, The American journal of physiology.

Early steps in hematogenous metastasis of B16F1 melanoma cells in chick embryos studied by high-resolution intravital videomicroscopy.

I. Macdonald, E. Schmidt, V. Morris, 1992, Journal of the National Cancer Institute.

The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells

I. Macdonald, E. Schmidt, V. Morris, 1999, Clinical & Experimental Metastasis.

Steps in tumor metastasis: new concepts from intravital videomicroscopy

R. Khokha, I. Macdonald, E. Schmidt, 1995, Cancer and Metastasis Reviews.

Measurement of the size distribution of human erythrocytes by a sedimentation method

J C Anderson, A. Groom, A C Groom, 1972, Journal of cellular physiology.

Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well.

R. Khokha, I. Macdonald, E. Schmidt, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy.

Christopher G Ellis, C. Ellis, I. Macdonald, 2005, American journal of physiology. Heart and circulatory physiology.

In vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model

C. Ellis, A. Ryan, I. Macdonald, 2004, Angiogenesis.

Effect of anesthesia on rate of N2 washout from body stores.

A. Groom, L. Farhi, Y. Ota, 1974, Journal of applied physiology.

Is inert gas washout from the tissues limited by diffusion?

A. Groom, L. Farhi, Y. Ohta, 1978, Journal of applied physiology: respiratory, environmental and exercise physiology.

Microvascular geometry in relation to modeling oxygen transport in contracted skeletal muscle.

C. Ellis, A. Groom, R. Potter, 2015, The American review of respiratory disease.

The high splenic hematocrit: a rheological consequence of red cell flow through the reticular meshwork.

I. Macdonald, E. Schmidt, A. Groom, 1991, Microvascular research.

Tumour metastasis to the liver, and the roles of proteinases and adhesion molecules: new concepts from in vivo videomicroscopy.

I. Macdonald, E. Schmidt, V. Morris, 1999, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Noninvasive Quantification of Tumor Volume in Preclinical Liver Metastasis Models Using Contrast-Enhanced X-Ray Computed Tomography

Maria Drangova, David W Holdsworth, Nancy L Ford, 2008, Investigative radiology.

The difference in circulation times between erythrocytes and plasma in vivo

A. Groom, S. Rowlands, H. Thomas, 1965 .

Reduction of sunburn damage to skin by topical application of vitamin E acetate following exposure to ultraviolet B radiation: effect of delaying application or of reducing concentration of vitamin E acetate applied.

D. Shum, S. Karlik, C. Norley, 1993, Scanning microscopy.

Simultaneous recording of the instantaneous counting rates of P32 and I131 in the blood stream of an animal.

A C GROOM, P W ROBERTS, S ROWLANDS, 1958, Biological sciences.

Unusual capillary network geometry in a skeletal muscle, as seen in microcorrosion casts of M. pectoralis of pigeon.

A. Groom, R. Potter, H. Dietrich, 1991, Microvascular research.

The authors' reply

I. Macdonald, E. Schmidt, V. Morris, 2009, British Journal of Psychiatry.

The Splanchnic Circulation

C. Zarins, P. Vaupel, H. Hutten, 1976 .

Metastasis: Dissemination and growth of cancer cells in metastatic sites

I. Macdonald, A. Chambers, A. Groom, 2002, Nature Reviews Cancer.

Temporal and spatial distributions of red cell velocity in capillaries of resting skeletal muscle, including estimates of red cell transit times.

C. Ellis, A. Groom, S. Fraser, 1981, Microvascular research.

Capillary network morphology and capillary flow.

C. Ellis, A. Groom, R. Potter, 1995, International journal of microcirculation, clinical and experimental.

Flow stasis, blood gases and glucose levels in the red pulp of the spleen.

A. Groom, M. Levesque, D. Brucksweiger, 1977, Advances in experimental medicine and biology.

Television-computer method for in vivo measurement of capillary diameter, based on the passage of red cells.

C. Ellis, A. Groom, R. G. Safranyos, 1983, Microvascular research.

Regulation of blood flow in individual capillaries of resting skeletal muscle in frogs.

A. Groom, K. Tyml, 1980, Microvascular research.

Ischemia-reperfusion induced microvascular dysfunction in skeletal muscle: application of intravital video microscopy.

C. Ellis, A. Groom, R. Potter, 1993, International journal of microcirculation, clinical and experimental.

Cutaneous diffusion of atmospheric N2 during N2 washout in the dog.

A. Groom, L. Farhi, 1967, Journal of applied physiology.

Effect of sarcomere length on total capillary length in skeletal muscle: in vivo evidence for longitudinal stretching of capillaries.

C. Ellis, I. Macdonald, A. Groom, 1990, Microvascular research.