C. Kasper

发表

Activation of mitomycin C by NADPH:cytochrome P-450 reductase.

C. Wolf, H. Bligh, A. Bartoszek, 1990, Cancer research.

Enzyme-substrate binding interactions of NADPH-cytochrome P-450 oxidoreductase characterized with pH and alternate substrate/inhibitor studies.

D. Sem, C. Kasper, 1993, Biochemistry.

Phenobarbital induction of NADPH-cytochrome c (P-450) oxidoreductase messenger ribonucleic acid.

C. Kasper, F. Gonzalez, 1980, Biochemistry.

Comparative studies on the endogenous phosphorylation of microsomal membrane derived from Morris hepatoma, eight-day-old rats, and host livers in the presence of micromolar levels of Mg2+ ion.

K. Lam, C. Kasper, 1981, Cancer research.

Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family.

D. Nebert, C. Kasper, F. Gonzalez, 1985, The Journal of biological chemistry.

Rapid method for preparation of crystalline human ceruloplasmin from Cohn fraction IV-1.

D. Walsh, C. Kasper, H. F. Deutsch, 1962, Archives of biochemistry and biophysics.

Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16 alpha-carbonitrile. Characterization of its mRNA, gene, and induction response.

C. Kasper, F. Gonzalez, J. Hardwick, 1983, The Journal of biological chemistry.

Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.

C. Kasper, J. Huss, A. Astrom, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

C. Kasper, D. Simmons, P. Lalley, 1985, The Journal of biological chemistry.

Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital.

C. Kasper, F. Gonzalez, J. Hardwick, 1983, The Journal of biological chemistry.

Binding Are Essential for Catalysis and Cofactor NADPH-Cytochrome P 450 Oxidoreductase Conformational Changes of Enzymology :

C. Kasper, L. Waskell, D. Hamdane, 2011 .

Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development.

C. Kasper, D. Simmons, Charles B. Kasper, 1989, Archives of biochemistry and biophysics.

Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.

C. Kasper, D. Simmons, P. McQuiddy, 1987, The Journal of biological chemistry.

Mixed-function amine oxidase of the rat hepatocyte nuclear envelope. Demonstration and effects of phenobarbital and 3-methylcholanthrene.

C. Kasper, C. Y. Sum, 1982, Biochemical pharmacology.

Preferential induction of aryl hydroxylase activity in rat liver nuclear envelope by 3-methylcholanthrene.

C. Kasper, A. Khandwala, 1973, Biochemical and biophysical research communications.

Selective phosphorylation of a nuclear envelope polypeptide by an endogenous protein kinase.

K. Lam, C. Kasper, 1979, Biochemistry.

Hepatic cytochrome P-448 and epoxide hydrase: enzymes of nuclear origin are immunochemically identical with those of microsomal origin.

W. E. Fahl, C. Kasper, E. Bresnick, 1979, Archives of biochemistry and biophysics.

In vitro translation of epoxide hydratase messenger RNA.

C. Kasper, F. Gonzalez, 1980, Biochemical and biophysical research communications.

Cloning and characterization of the rat NADPH-cytochrome P-450 oxidoreductase gene.

C. Kasper, F. Gonzalez, 1983, The Journal of biological chemistry.

Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes.

Frank, C. Kasper, F. J. Gonzalez, 1982, The Journal of biological chemistry.

Cloning of epoxide hydratase complementary DNA.

C. Kasper, F. Gonzalez, 1981, The Journal of biological chemistry.

The complete amino acid sequence of two types of subtilisin, BPN' and Carlsberg.

C. Kasper, E. L. Smith, R. Delange, 1966, The Journal of biological chemistry.

Membrane structure: The reactivity of tryptophan, tyrosine and lysine in proteins of the microsomal membrane

C. Kasper, A. Khandwala, 1971 .

Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase.

C. Kasper, H. Pitot, H. Inoue, 1971, The Journal of biological chemistry.

Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice.

C. Kasper, D. Simmons, 1983, The Journal of biological chemistry.

[26] Isolation and properties of the nuclear envelope

C. Kasper, 1974 .

6 – Chemical and Biochemical Properties of the Nuclear Envelope

C. Kasper, 1974 .

Sequential translocation of two phenobarbital-induced polysomal messenger ribonucleic acids from the nuclear envelope to the endoplasmic reticulum.

C. Kasper, F. Gonzalez, 1981, Biochemistry.

Interactions of nucleic acids and cellular membranes: behavior of membranes in CsCl density gradients.

C. Kasper, P. Gibbs, H. Kubinski, 1972, Biochimica et biophysica acta.

Ceruloplasmin-anion interactions. Induced spectral transitions in the visible range.

C. Kasper, 1968, The Journal of biological chemistry.

Immunochemical studies of crystalline human ceruloplasmin and derivatives.

C. Kasper, H. F. Deutsch, 1963, The Journal of biological chemistry.

Studies on the state of copper in native and modified human ceruloplasmin.

C. Kasper, H. Beinert, H. F. Deutsch, 1963, The Journal of biological chemistry.

The PPCD1 Mouse: Characterization of a Mouse Model for Posterior Polymorphous Corneal Dystrophy and Identification of a Candidate Gene

C. Murphy, R. Dubielzig, C. Kasper, 2010, PloS one.

Association of Multiple Developmental Defects and Embryonic Lethality with Loss of Microsomal NADPH-Cytochrome P450 Oxidoreductase*

C. Kasper, K. O'Leary, Anna L Shen, 2002, The Journal of Biological Chemistry.

Physicochemical studies of human ceruloplasmin.

C. Kasper, H. F. Deutsch, 1963, The Journal of biological chemistry.

Geometric relationship between the nicotinamide and isoalloxazine rings in NADPH-cytochrome P-450 oxidoreductase: implications for the classification of evolutionarily and functionally related flavoproteins.

D. Sem, C. Kasper, 1992, Biochemistry.

Effects of neuropharmacological agents on microsomal membrane: influence on deoxyribonucleic acid-membrane interactions in vitro.

C. Kasper, P. Andersen, H. Kubiński, 1974, Neuropharmacology.

Characterization of the membrane matrix derived from the microsomal fraction of rat hepatocytes.

M. Bornens, C. Kasper, G. Blackburn, 1976, Biochimica et biophysica acta.

Electrophoretic analysis of three major nuclear envelope polypeptides. Topological relationship and sequence homology.

K. Lam, C. Kasper, 1979, The Journal of biological chemistry.

Fractionation and partial characterization of proteins of the bileaflet nuclear membrane from rat liver.

M. Bornens, C. Kasper, 1973, The Journal of biological chemistry.

Isolation, morphology, and composition of the nuclear membrane from rat liver.

C. Kasper, D. M. Kashnig, 1969, The Journal of biological chemistry.

Chapter 1 – Glucuronidation

C. Kasper, D. Henton, 1980 .

Carcinogen and Microsomal Membrane Interactions: Changes in Membrane Density and Ability to Bind Nucleic Acids

C. Kasper, H. Kubiński, 1971, Science.

Differential Contributions of NADPH-Cytochrome P450 Oxidoreductase FAD Binding Site Residues to Flavin Binding and Catalysis*

C. Kasper, A. Shen, 2000, The Journal of Biological Chemistry.

Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase*

D. Sem, C. Kasper, A. Shen, 1999, The Journal of Biological Chemistry.

Sequence homology analysis of a heterogenous protein population by chemical and enzymic digestion using a two-dimensional sodium dodecyl sulfate-polyacrylamide gel system.

K. Lam, C. Kasper, 1980, Analytical biochemistry.

Characteristics of benzo(a)pyrene metabolism and cytochrome P-450 heterogeneity in rat liver nuclear envelope and comparison to microsomal membrane.

W. E. Fahl, C. Kasper, C. Jefcoate, 1978, The Journal of biological chemistry.

Biochemical distinctions between the nuclear and microsomal membranes from rat hepatocytes.

C. Kasper, 1971, The Journal of biological chemistry.

Role of Acidic Residues in the Interaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome P450 and Cytochrome c(*)

C. Kasper, A. Shen, 1995, The Journal of Biological Chemistry.

NADPH-cytochrome P-450 oxidoreductase gene organization correlates with structural domains of the protein.

C. Kasper, T. Beck, T. Porter, 1990, Biochemistry.

Determination of the rate of reduction of oxyferrous cytochrome P450 2B4 by 5-deazariboflavin adenine dinucleotide T491V cytochrome P450 reductase.

C. Kasper, L. Waskell, L. Gruenke, 2003, Biochemistry.

Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis.

T. E. Wilson, C. Kasper, T. Porter, 1989, The Journal of biological chemistry.

Fast Screening for the Purification of Proteins Using Membrane Adsorber Technology

T. Scheper, C. Kasper, J. Walter, 2007 .

Thyroid regulation of NADPH:cytochrome P450 oxidoreductase: identification of a thyroid-responsive element in the 5'-flank of the oxidoreductase gene.

D. Waxman, C. Kasper, K. O'Leary, 1997, Molecular pharmacology.

NADPH-Cytochrome P450 Oxidoreductase

C. Kasper, P. Hubbard, R. Paschke, 2001, The Journal of Biological Chemistry.

Transcriptional regulation of the TATA-less NADPH cytochrome P-450 oxidoreductase gene.

C. Kasper, K. O'Leary, P. McQuiddy, 1996, Archives of biochemistry and biophysics.

Purification and properties of microsomal UDP-glucuronosyltransferase from rat liver.

C. Kasper, J. Gorski, 1977, The Journal of biological chemistry.

Protein and Gene Structure and Regulation of NADPH-Cytochrome P450 Oxidoreductase

C. Kasper, A. Shen, 1993 .

Molecular basis for cell-specific regulation of the NADPH-cytochrome P450 oxidoreductase gene.

C. Kasper, K. O'Leary, 2000, Archives of biochemistry and biophysics.

Glucocorticoid repression and basal regulation of the epoxide hydrolase promoter.

C. Falany, C. Kasper, P. Bell, 1990, Archives of biochemistry and biophysics.

Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains.

C. Kasper, T. Porter, 1985, Proceedings of the National Academy of Sciences of the United States of America.

NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins.

C. Kasper, T. Porter, 1986, Biochemistry.

Complementary DNA and amino acid sequence of rat liver microsomal, xenobiotic epoxide hydrolase.

C. Kasper, T. Beck, T. Porter, 1986, Archives of biochemistry and biophysics.

Expression of a functional 78,000 dalton mammalian flavoprotein, NADPH-cytochrome P-450 oxidoreductase, in Escherichia coli.

T. E. Wilson, C. Kasper, T. Porter, 1987, Archives of biochemistry and biophysics.

Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding*

C. Kasper, L. Waskell, D. Hamdane, 2011, The Journal of Biological Chemistry.

Structure and organization of the microsomal xenobiotic epoxide hydrolase gene.

C. Falany, C. Kasper, P. McQuiddy, 1987, The Journal of biological chemistry.

Expression of rat microsomal epoxide hydrolase in Escherichia coli. Identification of a histidyl residue essential for catalysis.

C. Kasper, P. Bell, 1993, The Journal of biological chemistry.

Nuclear Receptor Involvement in the Regulation of Rat Cytochrome P450 3A23 Expression*

C. Kasper, J. Huss, 1998, The Journal of Biological Chemistry.

SUBTILISIN BPN'. I. PHYSICAL PROPERTIES AND AMINO ACID COMPOSITION.

H. Matsubara, C. Kasper, E. L. Smith, 1965, The Journal of biological chemistry.

UDP-glucuronosyltransferase: phospholipid dependence and properties of the reconstituted apoenzyme.

C. Kasper, J. Gorski, 1978, Biochemistry.

Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors.

C. Kasper, J. Huss, 2000, Molecular pharmacology.

Differential glucocorticoid responses of CYP3A23 and CYP3A2 are mediated by selective binding of orphan nuclear receptors.

C. Kasper, Steven I. Wang, J. Huss, 1999, Archives of biochemistry and biophysics.

Limited trypsin-catalyzed hydrolysis of crystalline human ceruloplasmin. Partial characterization of the digest.

C. Kasper, 1967, Biochemistry.

Interaction with arginine 597 of NADPH-cytochrome P-450 oxidoreductase is a primary source of the uniform binding energy used to discriminate between NADPH and NADH.

D. Sem, C. Kasper, 1993, Biochemistry.

31P NMR spectroscopic studies on purified, native and cloned, expressed forms of NADPH-cytochrome P450 reductase.

C. Kasper, B. Masters, J. Okita, 1992, Biochemistry.

Effect of ionic strength on the kinetic mechanism and relative rate limitation of steps in the model NADPH-cytochrome P450 oxidoreductase reaction with cytochrome c.

D. Sem, C. Kasper, 1995, Biochemistry.

NADPH-cytochrome P-450 oxidoreductase. The role of cysteine 566 in catalysis and cofactor binding.

C. Kasper, A. Shen, M. Christensen, 1991, The Journal of biological chemistry.

The fatty acid composition of individual phospholipids from rat liver nuclear membrane and nuclei.

C. Kasper, A. Khandwala, 1971, The Journal of biological chemistry.

Kinetic mechanism for the model reaction of NADPH-cytochrome P450 oxidoreductase with cytochrome c.

D. Sem, C. Kasper, 1994, Biochemistry.

NADPH cytochrome P-450 oxidoreductase gene: identification and characterization of the promoter region.

C. Kasper, T. Beck, K. O'Leary, 1994, Archives of biochemistry and biophysics.

Differential inducibility of nuclear envelope epoxide hydratase by trans-stilbene oxide and phenobarbital.

C. Kasper, F. Gonzalez, 1982, Molecular pharmacology.

Isolation and characterization of major intrinsic microsomal membrane proteins.

C. Kasper, G. Blackburn, 1976, The Journal of biological chemistry.

Fusion in vitro of membranes from animal cells.

C. Kasper, H. Kubiński, 1971, Nature: New biology.

Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

D. Nebert, C. Kasper, F. Gonzalez, 1986, Molecular and cellular biology.

SUBTILISIN BPN'. II. AMINO- AND CARBOXYL-TERMINAL SEQUENCES.

H. Matsubara, C. Kasper, E. L. Smith, 1965, The Journal of biological chemistry.

Selective endogenous phosphorylation of two liver microsomal polypeptides in the presence of micromolar levels of Mg2+ ion.

K. Lam, C. Kasper, 1980, The Journal of biological chemistry.

Immunological and biochemical characterization of nuclear envelope reduced nicotinamide adenine dinucleotide phosphate-cytochrome c oxidoreductase.

C. Kasper, J. J. Zimmerman, 1978, Archives of biochemistry and biophysics.

Subtilisin BPN'. 3. Isolation and sequence of 10 peptides from the tryptic digest.

C. Kasper, E. L. Smith, 1966, The Journal of biological chemistry.

SEA-TROSY (solvent exposed amides with TROSY): a method to resolve the problem of spectral overlap in very large proteins.

D. Sem, C. Kasper, M. Pellecchia, 2001, Journal of the American Chemical Society.