V. Sylvia

B. Boyan, D. Dean, V. Sylvia, 2002, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

1α,25-Dihydroxyvitamin D3 and 24R,25-Dihydroxyvitamin D3 Modulate Growth Plate Chondrocyte Physiology via Protein Kinase C-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase.

B. Boyan, D. Dean, V. Sylvia, 2002, Endocrinology.

Transforming growth factor-beta1 regulation of resting zone chondrocytes is mediated by two separate but interacting pathways.

B. Boyan, D. Dean, V. Sylvia, 2000, Biochimica et biophysica acta.

Phagocytosis of wear debris by osteoblasts affects differentiation and local factor production in a manner dependent on particle composition.

B. Boyan, C. Lohmann, D. Dean, 2000, Biomaterials.

Response of normal female human osteoblasts (NHOst) to 17beta-estradiol is modulated by implant surface morphology.

B. Boyan, C. Lohmann, D. Dean, 2002, Journal of biomedical materials research.

Expression and production of stathmin in growth plate chondrocytes is cell‐maturation dependent

B. Boyan, D. Dean, V. Sylvia, 2000, Journal of cellular biochemistry.

Effects of 1α,25‐(OH)2D3 on rat growth zone chondrocytes are mediated via cyclooxygenase‐1 and phospholipase A2

B. Boyan, D. Dean, V. Sylvia, 2001, Journal of cellular biochemistry. Supplement.

Both cyclooxygenase-1 and cyclooxygenase-2 mediate osteoblast response to titanium surface roughness.

B. Boyan, C. Lohmann, D. Dean, 2001, Journal of biomedical materials research.

The membrane effects of 17β-estradiol on chondrocyte phenotypic expression are mediated by activation of protein kinase C through phospholipase C and G-proteins

B. Boyan, D. Dean, V. Sylvia, 2000, The Journal of Steroid Biochemistry and Molecular Biology.

Regulation of protein kinase C by transforming growth factor β1 in rat costochondral chondrocyte cultures

B. Boyan, V. Sylvia, Z. Schwartz, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The kinase insert domain of colony stimulating factor‐1 receptor is dispensable for CSF‐1 induced phosphatidylcholine hydrolysis

V. Sylvia, G. G. Choudhury, Ling-mei Wang, 1991, FEBS letters.

Levels of endothelial nitric oxide synthase and calcitonin gene-related peptide in the Charcot foot: a pilot study.

L. Harkless, D. Carnes, V. Sylvia, 2008, The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons.

Lysophospholipid regulates release and activation of latent TGF-beta1 from chondrocyte extracellular matrix.

B. Boyan, V. Sylvia, Z. Schwartz, 2004, Biochimica et biophysica acta.

Evidence for distinct membrane receptors for 1α,25-(OH)2D3 and 24R,25-(OH)2D3 in osteoblasts

L. Bonewald, B. Boyan, D. Dean, 2002, Steroids.

1 (cid:1) ,25-Dihydroxyvitamin D 3 and 24R,25-Dihydroxyvitamin D 3 Modulate Growth Plate Chondrocyte Physiology via Protein Kinase C-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase

V. Sylvia, V. Bingham, H. Ehland, 2002 .

Nongenomic regulation of extracellular matrix events by vitamin D metabolites

B. Boyan, D. Dean, V. Sylvia, 1994, Journal of cellular biochemistry.

Identification of a Membrane Receptor for 1,25‐Dihydroxyvitamin D3 Which Mediates Rapid Activation of Protein Kinase C

B. Boyan, D. Dean, V. Sylvia, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Inhibition of cyclooxygenase by indomethacin modulates osteoblast response to titanium surface roughness in a time-dependent manner.

B. Boyan, C. Lohmann, D. Dean, 2001, Clinical oral implants research.

The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitro.

C. M. Agrawal, J. Mabrey, B. Boyan, 1999, The Journal of bone and joint surgery. American volume.

Metalloproteinase activity in growth plate chondrocyte cultures is regulated by 1,25-(OH)(2)D(3) and 24,25-(OH)(2)D(3) and mediated through protein kinase C.

B. Boyan, D. Dean, V. Sylvia, 2001, Matrix biology : journal of the International Society for Matrix Biology.

Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C

B. Boyan, D. Dean, V. Sylvia, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

Maturation State Determines the Response of Osteogenic Cells to Surface Roughness and 1,25‐Dihydroxyvitamin D3

L. Bonewald, B. Boyan, C. Lohmann, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Phospholipase A2 activating protein (PLAA) is required for 1α,25(OH)2D3 signaling in growth plate chondrocytes

D. Carnes, B. Boyan, V. Sylvia, 2005, Journal of cellular physiology.

Membrane actions of vitamin D metabolites 1α,25(OH)2D3 and 24R,25(OH)2D3 are retained in growth plate cartilage cells from vitamin D receptor knockout mice

B. Boyan, V. Sylvia, Z. Schwartz, 2003, Journal of cellular biochemistry.

1α,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-β activity via phospholipase A2-dependent production of lysophospholipid

B. Boyan, D. Dean, V. Sylvia, 2003, Steroids.

17β‐estradiol‐BSA conjugates and 17β‐estradiol regulate growth plate chondrocytes by common membrane associated mechanisms involving PKC dependent and independent signal transduction

D. Dean, V. Sylvia, Z. Schwartz, 2001, Journal of cellular biochemistry.

The Titanium-Bone Cell Interface In Vitro: The Role of the Surface in Promoting Osteointegration

B. Boyan, C. Lohmann, D. Dean, 2001 .

Nitric oxide donors selectively reduce the expression of matrix metalloproteinases-8 and -9 by human diabetic skin fibroblasts.

D. Dean, V. Sylvia, Weinan Zhong, 2007, The Journal of surgical research.

17β‐Estradiol regulation of protein kinase C activity in chondrocytes is sex‐dependent and involves nongenomic mechanisms

B. Boyan, D. Dean, V. Sylvia, 1998, Journal of cellular physiology.

Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes.

B. Boyan, D. Dean, V. Sylvia, 1999, Endocrinology.

Arachidonic acid is an autocoid mediator of the differential action of 1,25‐(OH)2D3 and 24,25‐(OH)2D3 on growth plate chondrocytes

B. Boyan, D. Dean, V. Sylvia, 1998, Journal of cellular physiology.

Hybrid structural analogues of 1,25‐(OH)2D3 regulate chondrocyte proliferation and proteoglycan production as well as protein kinase C through a nongenomic pathway

B. Boyan, D. Dean, V. Sylvia, 1997, Journal of cellular biochemistry.

A‐ring analogues of 1,25‐(OH)2D3 with low affinity for the vitamin D receptor modulate chondrocytes via membrane effects that are dependent on cell maturation

B. Boyan, D. Dean, V. Sylvia, 1997, Journal of cellular physiology.

Human colony stimulating factor-1 receptor activates the C-raf-1 proto-oncogene kinase.

A. Pfeifer, V. Sylvia, G. G. Choudhury, 1990, Biochemical and biophysical research communications.

Surface roughness mediates its effects on osteoblasts via protein kinase A and phospholipase A2.

B. Boyan, C. Lohmann, D. Dean, 1999, Biomaterials.

Surface roughness modulates the response of MG63 osteoblast-like cells to 1,25-(OH)(2)D(3) through regulation of phospholipase A(2) activity and activation of protein kinase A.

B. Boyan, C. Lohmann, D. Dean, 1999, Journal of biomedical materials research.

Decline of signal transduction by phospholipase Cγ1 in IMR 90 human diploid fibroblasts at high population doubling levels

V. Sylvia, G. G. Choudhury, A. Sakaguchi, 1991, FEBS letters.

Varying Ti-6Al-4V surface roughness induces different early morphologic and molecular responses in MG63 osteoblast-like cells.

H. Kim, M. Kim, D. Dean, 2005, Journal of biomedical materials research. Part A.

Interaction of phosphatidylinositol-4-monophosphate with a low activity form of DNA polymerase alpha: a potential mechanism for enzyme activation.

V. Sylvia, C. Joe, R. Tilley, 1989, The International journal of biochemistry.

Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.

B. Boyan, D. Dean, V. Sylvia, 2002, Biochimica et biophysica acta.

1a,25-(OH)2D3 Regulates 25-Hydroxyvitamin D3 24R-Hydroxylase Activity in Growth Zone Costochondral Growth Plate Chondrocytes via Protein Kinase C

B. Boyan, D. Dean, V. Sylvia, 2001, Calcified Tissue International.

24R,25‐(OH)2D3 mediates its membrane receptor‐dependent effects on protein kinase C and alkaline phosphatase via phospholipase A2 and cyclooxygenase‐1 but not cyclooxygenase‐2 in growth plate chondrocytes

B. Boyan, D. Dean, V. Sylvia, 2000, Journal of cellular physiology.

Matrix metalloproteinase expression in high grade soft tissue sarcomas.

L. Waite, V. Sylvia, J. Heim-Hall, 2007, Oncology reports.

Characterization of PGE2 receptors (EP) and their role as mediators of 1α,25-(OH)2D3 effects on growth zone chondrocytes

B. Boyan, D. Dean, V. Sylvia, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

Characterization of prostaglandin E2 receptors and their role in 24,25‐(OH)2D3‐mediated effects on resting zone chondrocytes

D. Dean, V. Sylvia, Z. Schwartz, 2000, Journal of cellular physiology.

1,25(OH)2D3 Regulates Protein Kinase C Activity Through Two Phospholipid‐Dependent Pathways Involving Phospholipase A2 and Phospholipase C in Growth Zone Chondrocytes

B. Boyan, D. Dean, V. Sylvia, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D3 regulation of stromelysin‐1 (MMP‐3) in chondrocyte cultures is mediated by protein kinase C

B. Boyan, D. Dean, V. Sylvia, 1996, Journal of cellular physiology.

The effect of 24R,25-(OH)2D3 on protein kinase C activity in chondrocytes is mediated by phospholipase D whereas the effect of 1α,25-(OH)2D3 is mediated by phospholipase C

B. Boyan, D. Dean, V. Sylvia, 2001, Steroids.

Bioavailability and Bioaccessibility of Arsenic in a Soil Amended with Drinking-Water Treatment Residuals

V. Sylvia, K. Makris, D. Sarkar, 2009, Archives of environmental contamination and toxicology.

Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of normal human osteoblast NHOst cells.

D. Carnes, B. Boyan, C. Lohmann, 2000, Journal of periodontology.

Plasma surface modification of poly(D,L-lactic acid) as a tool to enhance protein adsorption and the attachment of different cell types.

C. M. Alves, J. Ong, R. Reis, 2008, Journal of biomedical materials research. Part B, Applied biomaterials.

Platelet-derived growth-factor-releasing aligned collagen-nanoparticle fibers promote the proliferation and tenogenic differentiation of adipose-derived stem cells.

D. Nicolella, Xingguo Cheng, T. Bredbenner, 2014, Acta biomaterialia.

Pulsed electromagnetic fields affect phenotype and connexin 43 protein expression in MLO‐Y4 osteocyte‐like cells and ROS 17/2.8 osteoblast‐like cells

L. Bonewald, C. Lohmann, D. Dean, 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Rapid and long-term effects of PTH(1-34) on growth plate chondrocytes are mediated through two different pathways in a cell-maturation-dependent manner.

D. Graves, B. Boyan, D. Dean, 1997, Bone.

Effect of Porcine Fetal Enamel Matrix Derivative on Chondrocyte Proliferation, Differentiation, and Local Factor Production Is Dependent on Cell Maturation State

B. Boyan, C. Lohmann, D. Dean, 2002, Cells Tissues Organs.

The sesquiterpene lactone hymenoxon acts as a bifunctional alkylating agent

V. Sylvia, D. Busbee, Hyeong L. Kim, 1987, Cell Biology and Toxicology.

Phosphatidylinositol-dependent activation of DNA polymerase alpha.

V. Sylvia, C. Joe, D. Busbee, 1986, Biochemical and biophysical research communications.

V. Sylvia, R. Tilley, D. Busbee, 1989, Experimental Gerontology.

Purification of Norman Murine Sarcoma DNA polymerase alpha forms with different DNA template primer binding affinity and different specific activity.

V. Sylvia, D. Busbee, J. Norman, 1989, The International journal of biochemistry.

Effect of polymer molecular weight and addition of calcium stearate on response of MG63 osteoblast‐like cells to UHMWPE particles

C. Lohmann, D. Dean, V. Sylvia, 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The Synergistic Effects of Vitamin D Metabolites and Transforming Growth Factor-β on Costochondral Chondrocytes Are Mediated by Increases in Protein Kinase C Activity Involving Two Separate Pathways.

B. Boyan, D. Dean, V. Sylvia, 1998, Endocrinology.

Activation of a low specific activity form of DNA polymerase α by inositol-1,4-bisphosphate

V. Sylvia, D. Busbee, J. Norman, 1988, Cell.

1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C.

B. Boyan, D. Dean, V. Sylvia, 2001, Calcified tissue international.

Nongenomic regulation of protein kinase C isoforms by the vitamin D metabolites 1α,25‐(OH)2D3 and 24R,25‐(OH)2D3

B. Boyan, D. Dean, V. Sylvia, 1996, Journal of cellular physiology.

Evidence for distinct membrane receptors for 1 alpha,25-(OH)(2)D(3) and 24R,25-(OH)(2)D(3) in osteoblasts.

L. Bonewald, B. Boyan, D. Dean, 2002, Steroids.

Cell biology of calcified tissues: experimental models of differentiation and mechanisms by which local and systemic factors exert their effects.

B. Boyan, D. Dean, V. Sylvia, 1996, Connective tissue research.

Stathmin levels in growth plate chondrocytes are modulated by vitamin D3 metabolites and transforming growth factor-β1 and are associated with proliferation

B. Boyan, D. Dean, V. Sylvia, 2007, Endocrine.

Fiber-reinforced calcium phosphate cement formulations for cranioplasty applications: a 52-week duration preclinical rabbit calvaria study.

D. Dean, V. Sylvia, Jinku Kim, 2012, Journal of Biomedical Materials Research. Part B - Applied biomaterials.

Sex-specific regulation of growth plate chondrocytes by estrogen is via multiple MAP kinase signaling pathways.

B. Boyan, V. Sylvia, Z. Schwartz, 2006, Biochimica et biophysica acta.

24,25-(OH)2D3 Regulation of Matrix Vesicle Protein Kinase C Occurs Both During Biosynthesis and in the Extracellular Matrix

B. Boyan, D. Dean, V. Sylvia, 1997, Calcified Tissue International.

Effect of 17 beta-estradiol on chondrocyte membrane fluidity and phospholipid metabolism is membrane-specific, sex-specific, and cell maturation-dependent.

B. Boyan, D. Dean, V. Sylvia, 1996, Biochimica et biophysica acta.

1,25-(OH)2D3 modulates growth plate chondrocytes via membrane receptor-mediated protein kinase C by a mechanism that involves changes in phospholipid metabolism and the action of arachidonic acid and PGE2

D. Dean, V. Sylvia, Z. Schwartz, 1999, Steroids.

Lability of DNA polymerase alpha correlated with decreased DNA synthesis and increased age in human cells.

V. Sylvia, D. Busbee, J. Norman, 1987, Journal of the National Cancer Institute.

Prostaglandins mediate the effects of 1,25-(OH)2D3 and 24,25-(OH)2D3 on growth plate chondrocytes in a metabolite-specific and cell maturation-dependent manner.

B. Boyan, D. Dean, V. Sylvia, 1999, Bone.

Determination of deoxynivalenol (vomitoxin) by high-performance liquid chromatography with electrochemical detection.

V. Sylvia, L. Kubena, T. Phillips, 1986, Journal of chromatography.

Pretreatment of bone with osteoclasts affects phenotypic expression of osteoblast‐like cells

J. Puzas, B. Boyan, C. Lohmann, 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Bacterial lipopolysaccharide induces early and late activation of protein kinase C in inflammatory macrophages by selective activation of PKC-epsilon.

B. Boyan, D. Dean, V. Sylvia, 1997, Biochemical and biophysical research communications.

Comparison of Two Nanoparticle Formulations for Localized Delivery of Platelet-Derived Growth Factor (PDGF) from Aligned Collagen Fibers

Xingguo Cheng, V. Sylvia, J. Saul, 2013 .

Alkylation of deoxyguanosine by the sesquiterpene lactone hymenoxon.

V. Sylvia, C. Joe, R. Stipanovic, 1985, Toxicology letters.

Modulating bone cells response onto starch-based biomaterials by surface plasma treatment and protein adsorption.

C. M. Alves, J. Ong, R. Reis, 2007, Biomaterials.

Repair of benzo[a]pyrene-initiated DNA damage in human cells requires activation of DNA polymerase alpha.

V. Sylvia, C. Joe, D. Busbee, 1987, Mutation research.

Monoclonal antibody that blocks phosphoinositide-dependent activation of mouse tumor DNA polymerase alpha.

V. Sylvia, D. Busbee, J. Norman, 1986, Biochemical and biophysical research communications.

Physiological Importance of the 1,25(OH)2D3 Membrane Receptor and Evidence for a Membrane Receptor Specific for 24,25(OH)2D3

D. Dean, V. Sylvia, Z. Schwartz, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Steroid Hormone Action in Musculoskeletal Cells Involves Membrane Receptor and Nuclear Receptor Mechanisms

B. Boyan, D. Dean, V. Sylvia, 2003, Connective tissue research.

Rat costochondral chondrocytes produce 17β-estradiol and regulate its production by 1α,25(OH)2D3

B. Boyan, D. Dean, V. Sylvia, 2002 .

Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifen.

B. Boyan, C. Lohmann, D. Dean, 2003, Endocrinology.

Rapid-prototyped PLGA/β-TCP/hydroxyapatite nanocomposite scaffolds in a rabbit femoral defect model

Jinku Kim, J. Ong, B. Tellis, 2012, Biofabrication.

Shear force modulates osteoblast response to surface roughness.

B. Boyan, C. Lohmann, D. Dean, 2002, Journal of biomedical materials research.

In vivo performance of combinations of autograft, demineralized bone matrix, and tricalcium phosphate in a rabbit femoral defect model

D. Dean, V. Sylvia, Jinku Kim, 2014, Biomedical materials.