P. Grände

P. Grände, P. Bentzer, C. Lundblad, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Effects of Calcium Antagonists on Myogenic and Neurogenic Control of Resistance and Capacitance Vessels in Cat Skeletal Muscle

P. Grände, P. Borgström, D. Gustafsson, 1988, Journal of cardiovascular pharmacology.

Effects of dihydroergotamine on cerebral circulation during experimental intracranial hypertension

E. Ryding, P. Grände, C. Nordström, 1995, Acta anaesthesiologica Scandinavica.

Evidence for a rate-sensitive regulatory mechanism in myogenic microvascular control.

P. Grände, J. Lundvall, S. Mellander, 1977, Acta physiologica Scandinavica.

Temperature Management

P. Reinstrup, P. Grände, 2020, Management of Severe Traumatic Brain Injury.

Body Temperature in TBI Patients

B. Romner, P. Grände, 2012 .

Prostacyclin reduces elevation of intracranial pressure and plasma volume loss in lipopolysaccharide-induced meningitis in the cat.

P. Grände, P. Bentzer, M. Jungner, 2009, The Journal of trauma.

The Lund concept for the treatment of patients with severe traumatic brain injury.

P. Grände, 2011, Journal of neurosurgical anesthesiology.

PRO: the "Lund concept" for treatment of patients with severe traumatic brain injury.

P. Grände, 2011, Journal of neurosurgical anesthesiology.

Intracranial pressure following resuscitation with albumin or saline in a cat model of meningitis*

P. Grände, P. Bentzer, M. Jungner, 2011, Critical care medicine.

Effects on Brain Edema of Crystalloid and Albumin Fluid Resuscitation after Brain Trauma and Hemorrhage in the Rat

P. Grände, P. Bentzer, G. Mattiasson, 2010, Anesthesiology.

Time out for albumin or a valuable therapeutic component in severe head injury?

P. Grände, 2008, Acta anaesthesiologica Scandinavica.

Plasma volume expansion and transcapillary fluid exchange in skeletal muscle of albumin, dextran, gelatin, hydroxyethyl starch, and saline after trauma in the cat*

P. Grände, J. Persson, 2006, Critical care medicine.

Active cooling in traumatic brain‐injured patients: a questionable therapy?

P. Reinstrup, B. Romner, P. Grände, 2009, Acta anaesthesiologica Scandinavica.

HYPOVOLEMIA IS A MAIN FACTOR BEHIND DISTURBED PERFUSION AND METABOLISM IN THE INTESTINE DURING ENDOTOXEMIA IN CAT

P. Grände, Staffan Holbeck, 2002, Shock.

Treatment with the sphingosine‐1‐phosphate analogue FTY 720 reduces loss of plasma volume during experimental sepsis in the rat

P. Grände, C. Lundblad, Helen Axelberg, 2013, Acta anaesthesiologica Scandinavica.

The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner

B. Olde, P. Grände, V. Prasad, 2012, Molecular and Cellular Biochemistry.

Importance of the Infusion Rate for the Plasma Expanding Effect of 5% Albumin, 6% HES 130/0.4, 4% Gelatin, and 0.9% NaCl in the Septic Rat*

P. Grände, J. Persson, B. Bark, 2013, Critical care medicine.

Effects of thiopental on resistance vessels in cat skeletal muscle

P. Grände, D. Gustafsson, L. Lindberg, 2005, Intensive Care Medicine.

The effects of dihydroergotamine in patients with head injury and raised intracranial pressure

P. Grände, 2004, Intensive Care Medicine.

In vivo effects of prostacyclin on segmental vascular resistances, on myogenic reactivity, and on capillary fluid exchange in cat skeletal muscle.

P. Grände, U. Ekelund, J. Jahr, 1995, Critical care medicine.

Myogenic microvascular responses to change of transmural pressure. A mathematical approach.

P. Grände, P. Borgström, 1979, Acta physiologica Scandinavica.

The FLAMES score accurately predicts mortality risk in burn patients (Gomez M, et al. 2008).

P. Reinstrup, P. Grände, N. Brusselaers, 2009, The Journal of trauma.

Effects of Prostacyclin on Cerebral Blood Flow and Vasospasm After Subarachnoid Hemorrhage: Randomized, Pilot Trial

P. Grände, J. Wetterslev, J. Skjøth-Rasmussen, 2015, Stroke.

Pulmonary and haemodynamic effects of extracorporeal circulation in the cat and the beneficial effects of prostacyclin

P. Grände, J. Jahr, 2005, Intensive Care Medicine.

Beneficial effects of low-dose prostacyclin on cat intestinal perfusion during endotoxemia as evaluated with microdialysis and oxygen transport variables

P. Grände, A. D. Möller, 2001, Critical care medicine.

Treatment of Post-Traumatic Brain Edema

B. Asgeirsson, P. Grände, A. Larsson, 1995 .

A New Potential Therapy for Treatment of Posttraumatic Brain Oedema Based on Haemodynamic Principles for Brain Volume Regulation

B. Asgeirsson, P. Grände, C. Nordström, 1993 .

Vasopeptidase inhibition with omapatrilat increases fluid and protein microvascular permeability in cat skeletal muscle

P. Grände, P. Morsing, J. Persson, 2004, Journal of hypertension.

Effects of hypotensive treatment with α2‐agonist and β1‐antagonist on cerebral haemodynamics in severely head injured patients

B. Asgeirsson, P. Grände, C. Nordström, 1995 .

Nitric Oxide and Prostacyclin Play a Role in the Regulation of Microvascular Protein and Hydraulic Permeability in Cat Skeletal Muscle

P. Grände, U. Ekelund, J. Persson, 2003, Microcirculation.

Clinical studies in severe traumatic brain injury: a controversial issue

P. Grände, S. Naredi, 2002, Intensive Care Medicine.

Effects of arterial and venous pressure alterations on transcapillary fluid exchange during raised tissue pressure

B. Asgeirsson, P. Grände, 1994, Intensive Care Medicine.

The capillary filtration coefficient for evaluation of capillary fluid permeability in cat calf muscles.

P. Grände, L. Kongstad, 1998, Acta physiologica Scandinavica.

In vivo effects of tumor necrosis factor‐a on capillary permeability and vascular tone in a skeletal muscle

P. Grände, J. Jahr, 1996, Acta anaesthesiologica Scandinavica.

Possible role of short-term parenteral nutrition with fat emulsions for development of haemophagocytosis with multiple organ failure in a patient with traumatic brain injury

P. Grände, P. Nilsson-ehle, I. Eliasson, 2005, Intensive Care Medicine.

A mouse model for evaluation of capillary perfusion, microvascular permeability, cortical blood flow, and cortical edema in the traumatized brain.

P. Grände, P. Bentzer, C. Lundblad, 2004, Journal of neurotrauma.

Endogenous Nitric Oxide Reduces Microvascular Permeability and Tissue Oedema during Exercise in Cat Skeletal Muscle

P. Grände, U. Ekelund, J. Persson, 2003, Journal of Vascular Research.

Influence of neural and humoral beta-adrenoceptor stimulation on dynamic myogenic microvascular reactivity in cat skeletal muscle.

P. Grände, 1979, Acta physiologica Scandinavica.

, Hemorrhage : Randomized , Pilot Trial Effects of Prostacyclin on Cerebral Blood Flow and Vasospasm After Subarachnoid

P. Grände, J. Wetterslev, J. Skjøth-Rasmussen, 2014 .

Segmental cerebral vasoconstriction: Successful treatment of secondary cerebral ischaemia with intravenous prostacyclin

H. Bjartmarz, P. Grände, M. Cronqvist, 2010, Cephalalgia : an international journal of headache.

Responses of single arterioles in vivo in cat skeletal muscle to change in arterial pressure applied at different rates.

P. Grände, P. Borgström, L. Lindbom, 1981, Acta physiologica Scandinavica.

The effects of activated protein C and prostacyclin on arterial oxygenation and protein leakage in the lung and the gut under endotoxaemia in the rat

P. Grände, M. Dubniks, 2008, Acta anaesthesiologica Scandinavica.

Infusion rate and plasma volume expansion of dextran and albumin in the septic guinea pig

P. Grände, B. Bark, B. P. BARK, 2014, Acta anaesthesiologica Scandinavica.

Reflection coefficient for albumin and capillary fluid permeability in cat calf muscle after traumatic injury.

P. Grände, L. Kongstad, A. D. Möller, 1999, Acta physiologica Scandinavica.

Treatment of intracranial hypertension and aspects on lumbar dural puncture in severe bacterial meningitis

P. Grände, C. Nordström, E. Myhre, 2002, Acta anaesthesiologica Scandinavica.

Hemodynamic and histological effects of traumatic brain injury in eNOS-deficient mice.

P. Grände, P. Bentzer, C. Lundblad, 2009, Journal of neurotrauma.

Plasma volume expansion of 5% albumin, 4% gelatin, 6% HES 130/0.4, and normal saline under increased microvascular permeability in the rat

P. Grände, J. Persson, M. Dubniks, 2007, Intensive Care Medicine.

Low-dose prostacyclin restores an increased protein permeability after trauma in cat skeletal muscle.

P. Grände, P. Bentzer, 2004, The Journal of trauma.

Do conventional treatments of severe traumatic head injury worsen outcome?

P. Reinstrup, P. Grände, 2009, The Journal of trauma.

Local vascular response during organ elevation

P. Grände, L. Kongstad, 1999, Acta anaesthesiologica Scandinavica.

Mechanisms behind postspinal headache and brain stem compression following lumbar dural puncture – a physiological approach

P. Grände, 2005, Acta anaesthesiologica Scandinavica.

Severe traumatic brain injury management and clinical outcome using the Lund concept

P. Grände, L. Koskinen, M. Olivecrona, 2014, Neuroscience.

Effects on intracranial pressure of dural puncture in supine and head‐elevated positions. A study on the cat

P. Grände, L. Kongstad, 2005, Acta anaesthesiologica Scandinavica.

Physiologic principles for volume regulation of a tissue enclosed in a rigid shell with application to the injured brain.

B. Asgeirsson, P. Grände, C. Nordström, 1997, The Journal of trauma.

Peripheral circulatory effects of pump perfusion on cat skeletal muscle with and without prostacyclin.

P. Grände, J. Jahr, 1997, Acta physiologica Scandinavica.

A servo-controlled roller pump for constant flow or constant pressure blood perfusion under normal pulsatile or non-pulsatile conditions.

P. Grände, P. Borgström, L. Clementz, 1981, Acta Physiologica Scandinavica.

Treatment of traumatic head injury--U.S./European guidelines or the Lund concept.

P. Grände, C. Nordström, M. Vegfors, 2003, Critical care medicine.

Capillary filtration coefficient is independent of number of perfused capillaries in cat skeletal muscle.

P. Grände, P. Bentzer, L. Kongstad, 2001, American journal of physiology. Heart and circulatory physiology.

Effects of hypertonic saline, mannitol, and urea with regard to absorption and rebound filtration in cat skeletal muscle

P. Grände, P. Bentzer, Staffan Holbeck, 2002, Critical care medicine.

Plasma Volume Expansion by 0.9% NaCl During Sepsis/Systemic Inflammatory Response Syndrome, After Hemorrhage, and During a Normal State

P. Grände, C. Öberg, B. Bark, 2013, Shock.

An outcome study of severe traumatic head injury using the “Lund therapy” with low‐dose prostacyclin

P. Grände, L. Koskinen, M. Olivecrona, 2001, Acta anaesthesiologica Scandinavica.

Endotoxin increases both protein and fluid microvascular permeability in cat skeletal muscle

P. Grände, Staffan Holbeck, 2003, Critical care medicine.

Volume expansion of albumin, gelatin, hydroxyethyl starch, saline and erythrocytes after haemorrhage in the rat

P. Grände, J. Persson, 2005, Intensive Care Medicine.

Low‐dose prostacyclin in treatment of severe brain trauma evaluated with microdialysis and jugular bulb oxygen measurements

U. Ungerstedt, P. Grände, C. Nordström, 2000, Acta anaesthesiologica Scandinavica.

Comparison of the plasma volume-expanding effects of 6% dextran 70, 5% albumin, and 6% HES 130/0.4 after hemorrhage in the guinea pig.

P. Grände, J. Persson, M. Dubniks, 2009, The Journal of trauma.

Dextran, gelatin, and hydroxyethyl starch do not affect permeability for albumin in cat skeletal muscle

P. Grände, P. Bentzer, Staffan Holbeck, 2001, Critical care medicine.

Improved outcome after severe head injury with a new therapy based on principles for brain volume regulation and preserved microcirculation.

C. Eker, W. Schalén, B. Asgeirsson, 1998, Critical care medicine.

The “Lund Concept” for the treatment of severe head trauma – physiological principles and clinical application

P. Grände, Per-Olof Grände, 2006, Intensive Care Medicine.

Inhibition of Rho kinase decreases hydraulic and protein microvascular permeability in cat skeletal muscle.

P. Grände, P. Bentzer, C. Lundblad, 2003, Microvascular research.

A MODEL FOR EVALUATING THE EFFECTS OF BLUNT SKELETAL MUSCLE TRAUMA ON MICROVASCULAR PERMEABILITY AND PLASMA VOLUME IN THE RAT

P. Grände, P. Bentzer, C. Lundblad, 2010, Shock.

A new therapy of post-trauma brain oedema based on haemodynamic principles for brain volume regulation

B. Asgeirsson, P. Grände, C. Nordström, 2005, Intensive Care Medicine.

A Consensus-Based Interpretation of the Benchmark Evidence from South American Trials: Treatment of Intracranial Pressure Trial.

S. Mayer, D. Okonkwo, D. Menon, 2015, Journal of neurotrauma.

Volume‐targeted therapy of increased intracranial pressure: the Lund concept unifies surgical and non‐surgical treatments

B. Asgeirsson, P. Grände, C. Nordström, 2002, Acta anaesthesiologica Scandinavica.

Myogenic vascular regulation in skeletal muscle in vivo is not dependent of endothelium-derived nitric oxide.

P. Grände, S. Mellander, U. Ekelund, 1992, Acta physiologica Scandinavica.

Low-dose prostacyclin improves cortical perfusion following experimental brain injury in the rat.

P. Grände, D. Venturoli, O. Carlsson, 2003, Journal of neurotrauma.

Dynamic and static components in the myogenic control of vascular tone in cat skeletal muscle.

P. Grände, 1979, Acta Physiologica Scandinavica Supplementum.

Therapeutic Hypothermia in Children and Adults with Severe Traumatic Brain Injury.

B. Romner, P. Grände, Anna Sandestig, 2014, Therapeutic hypothermia and temperature management.

Low-dose prostacyclin has potent capillary permeability-reducing effect in cat skeletal muscle in vivo.

P. Grände, A. D. Möller, 1997, The American journal of physiology.

The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle.

P. Grände, P. Bentzer, C. Lundblad, 2004, Microvascular research.

Endothelin-1 reduces microvascular fluid permeability through secondary release of prostacyclin in cat Skeletal muscle.

P. Grände, P. Bentzer, Staffan Holbeck, 2002, Microvascular research.

Prostacyclin Reduces Microvascular Fluid Conductivity in Cat Skeletal Muscle through Opening of ATP-Dependent Potassium Channels

P. Grände, P. Bentzer, Staffan Holbeck, 1999, Journal of Vascular Research.

Effects of hypotensive treatment with alpha 2-agonist and beta 1-antagonist on cerebral haemodynamics in severely head injured patients.

E. Ryding, B. Asgeirsson, P. Grände, 1995, Acta anaesthesiologica Scandinavica.

[Current alternative therapy of post-traumatic brain edema].

B. Asgeirsson, P. Grände, C. Nordström, 1994, Nordisk medicin.

Management of Fluids and Electrolytes

N. Juul, P. Grände, 2020 .

Fluid Haemodynamics in Patients with Severe TBI

N. Juul, P. Grände, 2012 .

New therapeutic strategies in head trauma

N. Latronico, B. Asgeirsson, P. Grände, 1995, Intensive Care Medicine.

Pathophysiology of brain insult. Therapeutic implications with the Lund Concept.

P. Grände, 2000, Schweizerische medizinische Wochenschrift.

Management of Severe Traumatic Brain Injury

Bertil Romner, N. Juul, B. Romner, 2012 .

Isolated Brain Trauma in Cats Triggers Rapid Onset of Hypovolemia

P. Grände, P. Bentzer, 2016, Neurocritical Care.

Conventional treatments for severe head injury: are they effective, ineffective, or even harmful?

P. Reinstrup, B. Romner, P. Grände, 2007, Acta anaesthesiologica Scandinavica.

Change in plasma volume from a state of hyper-, normo- or hypovolemia with or without noradrenalin infusion in the rat.

P. Grände, M. Dubniks, 2008, Microvascular research.

Effect of blood pressure on plasma volume loss in the rat under increased permeability

P. Grände, J. Persson, M. Dubniks, 2007, Intensive Care Medicine.

The effects of activated protein C and prostacyclin on arterial oxygenation and protein leakage in the lung and the gut under endotoxaemia in the rat

P. Grände, M. Dubniks, 2008, Acta anaesthesiologica Scandinavica.

The Lund Therapy: A Physiological Approach

P. Reinstrup, P. Grände, 2020 .

Segmental cerebral vasoconstriction: Successful treatment of secondary cerebral ischaemia with intravenous prostacyclin

H. Bjartmarz, P. Grände, M. Cronqvist, 2010, Cephalalgia : an international journal of headache.

Hypertonic saline: a marker for discrimination between a disrupted and intact blood-brain barrier?

P. Grände, P. Bentzer, 2006, Critical Care Medicine.