L. Jenkins

S. Wisniewski, P. Kochanek, J. Melick, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Traumatic Brain Injury: Laboratory Studies

P. Kochanek, R. Clark, L. Jenkins, 2005 .

Autophagy is Increased after Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant γ-glutamylcysteinyl Ethyl Ester

Simon C Watkins, P. Kochanek, R. Clark, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Selectively increasing inducible heat shock protein 70 via TAT‐protein transduction protects neurons from nitrosative stress and excitotoxicity

R. Clark, H. Wong, L. Jenkins, 2005, Journal of neurochemistry.

Mild traumatic brain injury does not modify the cerebral blood flow profile of secondary forebrain ischemia in Wistar rats.

D. Prough, D. Dewitt, L. Jenkins, 1998, Journal of neurotrauma.

Lamotrigine attenuates cortical glutamate release during global cerebral ischemia in pigs on cardiopulmonary bypass.

D. Dewitt, L. Jenkins, R. Crumrine, 1999, Anesthesiology.

Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: A feasibility trial*

P. Kochanek, Jesse A. Fisk, R. Garman, 2007, Critical care medicine.

Histopathologic consequences of hyperglycemic cerebral ischemia during hypothermic cardiopulmonary bypass in pigs.

M. Grafe, D. Dewitt, L. Jenkins, 2001, The Annals of thoracic surgery.

Increased vulnerability of the mildly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury.

G. Clifton, T. J. Majewski, D. Dewitt, 1989, Brain research.

Hyperglycemia during Hypothermic Canine Cardiopulmonary Bypass Increases Cerebral Lactate

D. Prough, L. Jenkins, W. Johnston, 1995, Anesthesiology.

Increased Vulnerability of the Traumatized Brain to Early Ischemia

A. Marmarou, L. Jenkins, D. Becker, 1986 .

Hyperglycemia during Hypothermic Canine Cardiopulmonary Bypass Increases Cerebral Lactate

D. Prough, L. Jenkins, W. Johnston, 1995, Anesthesiology.

Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats

P. Kochanek, D. Marion, C. Dixon, 2002, Brain Research.

Severe brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice.

S. Wisniewski, P. Kochanek, R. Clark, 2012, Journal of neurotrauma.

Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death.

P. Kochanek, R. Clark, H. Bayır, 2009, Journal of neurotrauma.

Acute etomidate treatment reduces cognitive deficits and histopathology in rats with traumatic brain injury

S. Wisniewski, P. Kochanek, D. Marion, 2003, Critical care medicine.

Secondary Injury after Clinical Traumatic Brain Injury

D. Prough, D. Dewitt, L. Jenkins, 1997 .

Regional calcineurin subunit B isoform expression in rat hippocampus following a traumatic brain injury

C. Dixon, L. Jenkins, J. Bales, 2010, Brain Research.

The morphopathologic substrates of concussion?

J. Miller, J. Povlishock, L. Jenkins, 1979, Acta Neuropathologica.

A scanning electron-microscopic analysis of the intraparenchymal brain vasculature following experimental hypertension

J. Povlishock, L. Jenkins, D. Becker, 2004, Acta Neuropathologica.

The effect of age on motor and cognitive deficits after traumatic brain injury in rats.

R. Hayes, L. Jenkins, R. Hamm, 1992, Neurosurgery.

Cerebral Concussion Suppresses Hippocampal Long-term Potentiation (LTP) in Rats

Y. Katayama, R. Hayes, L. Jenkins, 1989 .

Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology

P. Kochanek, J. Melick, R. Clark, 2002, Brain Research.

A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury.

D. Allen, G. Omenn, P. Kochanek, 2007, Journal of neurotrauma.

HBO: It's not ready for prime time for the treatment of acute central nervous system trauma.

P. Kochanek, R. Clark, L. Jenkins, 2001, Critical care medicine.

Enhanced vulnerability to secondary ischemic insults after experimental traumatic brain injury.

D. Prough, D. Dewitt, L. Jenkins, 1995, New horizons.

Experimental model of pediatric asphyxial cardiopulmonary arrest in rats

P. Kochanek, R. Clark, C. D. Marco, 2004, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Pathobiology of Secondary Brain Injury

P. Kochanek, R. Clark, L. Jenkins, 2012 .

Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury

P. Kochanek, R. Clark, L. Jenkins, 2004, Critical care.

The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injury.

B. Pike, L. Jenkins, R. Hamm, 1994, Journal of neurotrauma.

Combined pretrauma scopolamine and phencyclidine attenuate posttraumatic increased sensitivity to delayed secondary ischemia.

G. Clifton, R. Hayes, D. Dewitt, 1988, Journal of neurotrauma.

Marked Protection by Moderate Hypothermia after Experimental Traumatic Brain Injury

G. Clifton, R. Hayes, L. Jenkins, 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Appearance of Superoxide Anion Radical in Cerebral Extracellular Space during Increased Prostaglandin Synthesis in Cats

J. Povlishock, L. Jenkins, M. Hess, 1985, Circulation research.

Enduring suppression of hippocampal long-term potentiation following traumatic brain injury in rat

Y. Katayama, R. Hayes, D. Dewitt, 1992, Brain Research.

Neurotransmitter and Growth Factor Alterations in Functional Deficits and Recovery Following Traumatic Brain Injury

C. Dixon, L. Jenkins, H. Yan, 2001 .

Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats.

S. Wisniewski, P. Kochanek, K. Statler, 2000, Journal of neurotrauma.

Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats.

P. Kochanek, D. Marion, R. Clark, 2002, Journal of neurotrauma.

Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making

Rachel P Berger, P. Kochanek, R. Clark, 2008, Current opinion in critical care.

Posttranslational protein modifications.

R. Clark, H. Bayır, L. Jenkins, 2005, Critical care medicine.

Neurotransmitter-mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids.

R. Hayes, L. Jenkins, B. Lyeth, 1992, Journal of neurotrauma.

Polynitroxylated pegylated hemoglobin: A novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice*

P. Kochanek, H. Bayır, C. Dixon, 2011, Critical care medicine.

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice.

P. Kochanek, G. Homanics, M. Bell, 2010, Journal of neurotrauma.

Adenosine A1 Receptor Knockout Mice Develop Lethal Status Epilepticus after Experimental Traumatic Brain Injury

P. Kochanek, R. Clark, P. Crumrine, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Increased vulnerability of the midly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury

G. Clifton, T. J. Majewski, R. Hayes, 1989, Brain Research.

Traumatic brain injury in rats results in increased expression of Gap-43 that correlates with behavioral recovery

C. Hulsebosch, D. Prough, D. Dewitt, 1998, Neuroscience Letters.

Postnatal growth, neurobehavioral and neurophysiologic changes of prenatal low-dose beta-radiation from tritiated water in mice.

C. Dixon, L. Jenkins, Wei Zhang, 2002, Neurotoxicology and teratology.

Effects of fluid-percussion brain injury on regional cerebral blood flow and pial arteriolar diameter.

D. Dewitt, L. Jenkins, D. Becker, 1986, Journal of neurosurgery.

Histopathologic response of the immature rat to diffuse traumatic brain injury.

P D Adelson, P. Kochanek, L. Jenkins, 2001, Journal of neurotrauma.

Inflicted Childhood Neurotrauma: New Insight into The Detection, Pathobiology, Prevention, and Treatment of Our Youngest Patients with Traumatic Brain Injury

Susan S. Margulies, Rachel P. Berger, P. Kochanek, 2007 .

Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats

P. Kochanek, J. Melick, K. Statler, 2003, Brain Research.

Moderate hypothermia may be detrimental after traumatic brain injury in fentanyl-anesthetized rats

P. Kochanek, K. Statler, D. Marion, 2003, Critical care medicine.

Cognitive deficits following traumatic brain injury produced by controlled cortical impact.

R. Hayes, C. Dixon, L. Jenkins, 1992, Journal of neurotrauma.

Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.

P. Kochanek, K. Statler, R. Clark, 2006, Journal of neurotrauma.

Effect of D, alpha-tocopheryl succinate and polyethylene glycol on performance tests after fluid percussion brain injury.

G. Clifton, R. Hayes, L. Jenkins, 1989, Journal of neurotrauma.

Are the Pathobiological Changes Evoked by Traumatic Brain Injury Immediate and Irreversible?

J. Povlishock, L. Jenkins, 1995, Brain pathology.

Effects of experimental fluid-percussion injury of the brain on cerebrovascular reactivity of hypoxia and to hypercapnia.

J. Miller, L. Jenkins, W. Lewelt, 1982, Journal of neurosurgery.

Autoregulation of cerebral blood flow after experimental fluid percussion injury of the brain.

J. Miller, L. Jenkins, W. Lewelt, 1980, Journal of neurosurgery.

Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury

P. Kochanek, K. Statler, R. Clark, 2006, Brain Research.

Expression of protein phosphatase 2B (calcineurin) subunit A isoforms in rat hippocampus after traumatic brain injury.

C. Dixon, L. Jenkins, J. Bales, 2010, Journal of neurotrauma.

Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury.

Valerian Kagan, P. Kochanek, R. Clark, 2011, Journal of neurotrauma.

Biochemical, cellular, and molecular mechanisms in the evolution of secondary damage after severe traumatic brain injury in infants and children: Lessons learned from the bedside

P. Kochanek, D. Marion, R. Clark, 2000, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

The simple model versus the super model: translating experimental traumatic brain injury research to the bedside.

P. Kochanek, K. Statler, D. Marion, 2001, Journal of neurotrauma.

Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat

G. Clifton, R. Hayes, C. Dixon, 1990, Brain Research.

Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat

J. Povlishock, L. Jenkins, B. Lyeth, 2004, Acta Neuropathologica.

Brief Induced Hypothermia Improves Outcome after Asphyxial Cardiopulmonary Arrest in Juvenile Rats

P. Kochanek, R. Clark, C. D. Marco, 2005, Developmental Neuroscience.

Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats.

P. Kochanek, R. Clark, H. Bayır, 2013, Journal of neurotrauma.

Evaluation of combined fibroblast growth factor-2 and moderate hypothermia therapy in traumatically brain injured rats

D. Marion, C. Dixon, L. Jenkins, 2000, Brain Research.

A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ

P. Kochanek, J. Melick, C. Dixon, 2003, Journal of neurochemistry.

The Safar Center for Resuscitation Research: Searching for Breakthroughs in the New Millennium

P. Kochanek, R. Clark, H. Bayır, 2006 .

Gel-Based Hippocampal Proteomic Analysis 2 Weeks following Traumatic Brain Injury to Immature Rats Using Controlled Cortical Impact

R. Clark, C. Dixon, L. Jenkins, 2006, Developmental Neuroscience.

Increased Phosphorylation of Protein Kinase B and Related Substrates after Traumatic Brain Injury in Humans and Rats

P. Kochanek, D. Marion, S. DeKosky, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Selective cognitive impairment following traumatic brain injury in rats

B. Pike, L. Jenkins, R. Hamm, 1993, Behavioural Brain Research.

Identification of poly‐ADP‐ribosylated mitochondrial proteins after traumatic brain injury

Simon C Watkins, P. Kochanek, R. Clark, 2008, Journal of neurochemistry.

Pressure-dependent Collateral Perfusion during Cerebral Ischemia in Pigs on Bypass

D. Dewitt, L. Jenkins, W. Johnston, 1998 .

Biochemical and Molecular Mechanisms after Severe Traumatic Brain Injury in Children

P. Kochanek, L. Jenkins, R. Berger, 2002 .

Regional rates of glucose utilization in the cat following concussive head injury.

G. Clifton, Y. Katayama, R. Hayes, 1988, Journal of neurotrauma.

Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats.

P. Kochanek, R. Clark, C. Dixon, 2006 .