Yumay Chen

发表

Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact

S. Jacobsen, P. G. Yazdi, B. Pedersen, 2015, PloS one.

Hot-Spot p53Mutants Interact Specifically withTwoCellular Proteins during Progression oftheCellCycle

Yumay Chen, Phang-lang Chen, Wen-Hwa Lee, 1994 .

Mechanisms of Mitochondrial Damage in Keratinocytes by Pemphigus Vulgaris Antibodies*

Yumay Chen, Ping H Wang, S. Grando, 2013, The Journal of Biological Chemistry.

Wu Antibodies Keratinocytes by Pemphigus Vulgaris Mechanisms of Mitochondrial Damage in Molecular Bases of Disease

Yumay Chen, Ping H Wang, S. Grando, 2013 .

Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites

Amanda J. Kedaigle, E. Fraenkel, M. MacDonald, 2019, Human Molecular Genetics.

A Three-Dimensional Printed Inertial Microfluidic Platform for Isolation of Minute Quantities of Vital Mitochondria.

D. Wallace, Yumay Chen, ChiaHung Lee, 2022, Analytical chemistry.

Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease

Huai-Chin Chiang, D. Riley, Yumay Chen, 2014, Journal of Biomedical Science.

NAD+ consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival

M. Berns, M. Digman, Yumay Chen, 2019, Molecular biology of the cell.

NAD consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival

M. Berns, M. Digman, Yumay Chen, 2018, bioRxiv.

Never-in-mitosis related Kinase 1 functions in DNA damage response and checkpoint control

D. Riley, Yumay Chen, Phang-lang Chen, 2008, Cell cycle.

Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR

D. Riley, Yumay Chen, Phang-lang Chen, 2011, Cell cycle.

Impaired translocation and activation of mitochondrial Akt1 mitigated mitochondrial oxidative phosphorylation Complex V activity in diabetic myocardium.

D. Wallace, Yumay Chen, Ping H Wang, 2013, Journal of molecular and cellular cardiology.

Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells

Michael D. Zeller, P. Baldi, O. Fiehn, 2016, Cancer & Metabolism.

Tubular mitochondrial AKT1 is activated during ischemia reperfusion injury and has a critical role in predisposition to chronic kidney disease.

H. Y. Lin, Yu-Han Chen, Yumay Chen, 2020, Kidney international.

Aberrant DNA damage response and DNA repair pathway in high glucose conditions.

D. Riley, Yumay Chen, Phang-lang Chen, 2018, Journal of cancer research updates.

Diabetes-Cancer Risk: Hyperglycemia on DNA Damage and Repair

Yumay Chen, Phang-lang Chen, Amy Zhong, 2019, American Journal of Biomedical Science & Research.

Identification of Cellular TSG1O1 Protein in Multiple Human Breast Cancer Cell Lines'

Yumay Chen, Phang-lang Chen, Wen-Hwa Lee, 2006 .

Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris*

Yumay Chen, Ping H Wang, S. Grando, 2015, The Journal of Biological Chemistry.

D. Riley, R. Polci, Yumay Chen, 2004, Cancer Research.

Pemphigus vulgaris antibodies target the mitochondrial nicotinic acetylcholine receptors that protect keratinocytes from apoptolysis.

Yumay Chen, Ping H Wang, S. Grando, 2015, International immunopharmacology.

4-Hydroxytamoxifen probes for light-dependent spatiotemporal control of Cre-ER mediated reporter gene expression.

Yumay Chen, M. Inlay, S. Choi, 2015, Molecular bioSystems.

The role of EGFR double minutes in modulating the response of malignant gliomas to radiotherapy

Yi-Hong Zhou, Yumay Chen, Ping H Wang, 2017, Oncotarget.

Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1

Ken W. Y. Cho, Kitt D. Paraiso, Kang Du, 2021, JCI insight.

Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1

W. Craigen, D. Riley, Yumay Chen, 2009, Cell cycle.

Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1.

D. Riley, R. Polci, Yumay Chen, 2010, Biochemical and biophysical research communications.

The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor*

Yumay Chen, Phang-lang Chen, Wen-Hwa Lee, 1996, The Journal of Biological Chemistry.

Aberrant Subcellular Localization of BRCA1 in Breast Cancer

C. Osborne, Y. Chen, C. F. Chen, 1995, Science.

Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation*

D. Riley, Yumay Chen, Phang-lang Chen, 2002, The Journal of Biological Chemistry.

Nucleosome Organization in Human Embryonic Stem Cells

S. Jacobsen, P. G. Yazdi, B. Pedersen, 2015, PloS one.

Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells

Matthew A. Kayala, P. Baldi, Yu-Han Chen, 2019, Scientific Reports.

Advances in Brief Identification of Cellular TSG 1 O 1 Protein in Multiple Human Breast Cancer Cell Lines '

Yumay Chen, Phang-lang Chen, Wen-Hwa Lee, 2006 .

Emerging roles of BRCA1 in transcriptional regulation and DNA repair

Yumay Chen, Wen-Hwa Lee, H. Chew, 1999, Journal of cellular physiology.

Inactivation of CtIP Leads to Early Embryonic Lethality Mediated by G1 Restraint and to Tumorigenesis by Haploid Insufficiency

F. Liu, Yumay Chen, Phang-lang Chen, 2005, Molecular and Cellular Biology.

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment

D. Riley, R. Polci, Yumay Chen, 2014, Oncotarget.

HEC Binds to the Seventh Regulatory Subunit of the 26 S Proteasome and Modulates the Proteolysis of Mitotic Cyclins*

Yumay Chen, Wen-Hwa Lee, Z. D. Sharp, 1997, The Journal of Biological Chemistry.

Hice1, a Novel Microtubule-Associated Protein Required for Maintenance of Spindle Integrity and Chromosomal Stability in Human Cells

Yumay Chen, Wen-Hwa Lee, Guikai Wu, 2008, Molecular and Cellular Biology.

Linking differential radiation responses to glioma heterogeneity

Yi-Hong Zhou, Yumay Chen, Ping H Wang, 2014, Oncotarget.

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

Huai-Chin Chiang, R. Edwards, D. Riley, 2011, Molecular Cancer.

Retinoblastoma Protein Enhances the Fidelity of Chromosome Segregation Mediated by hsHec1p

D. Riley, Yumay Chen, Phang-lang Chen, 2000, Molecular and Cellular Biology.

Mitochondrial Akt-regulated mitochondrial apoptosis signaling in cardiac muscle cells.

Yumay Chen, Jia-Ying Yang, Ping H. Wang, 2012, American journal of physiology. Heart and circulatory physiology.

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan

D. Wallace, Yumay Chen, Phang-lang Chen, 2012, Oncogene.

Tracking Functional Tumor Cell Subpopulations of Malignant Glioma by Phasor Fluorescence Lifetime Imaging Microscopy of NADH

Yi-Hong Zhou, M. Digman, Yumay Chen, 2017, Cancers.

Recruitment of Thyroid Hormone Receptor/Retinoblastoma-interacting Protein 230 by the Aryl Hydrocarbon Receptor Nuclear Translocator Is Required for the Transcriptional Response to Both Dioxin and Hypoxia*

Robert T. Taylor, Timothy V. Beischlag, Wen-Hwa Lee, 2004, Journal of Biological Chemistry.

Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment

Yi-Hong Zhou, Yumay Chen, Yuanjie Hu, 2015, Oncotarget.

The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming.

J. I. Izpisúa Belmonte, K. Kessenbrock, P. Sassone-Corsi, 2023, Cell reports.

NEK1 Protein Kinase as a Target for Anticancer Therapeutics

Yumay Chen, 2012 .

Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease

Huai-Chin Chiang, D. Riley, Yumay Chen, 2014, Journal of Biomedical Science.

Association between the risk of heart failure hospitalization and end-stage renal disease with digoxin usage in patients with cardiorenal syndrome: A population-based study

H. Y. Lin, Yumay Chen, Jer-Ming Chang, 2023, Frontiers in Public Health.

Genetic mechanisms of tumor suppression by the human p53 gene

Yumay Chen, Phang-lang Chen, Wen-Hwa Lee, 1990, Science.

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.

D. Kaiser, M. Rosenfeld, D. Riley, 1993, Genes & development.

A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock

Y. Chen, C. F. Chen, D. Riley, 1996, Molecular and cellular biology.

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response.

C. Wang, Y. Chen, C. F. Chen, 1999, Science.

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

Y. Chen, D. Riley, W. Lee, 1996, Genes & development.

Perturbation of TSG101 protein affects cell cycle progression.

Y. Chen, W. Lee, Diane Jones, 1998, Cancer research.

BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner.

Y. Chen, C. F. Chen, W. Lee, 1996, Cancer research.

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.

Y. Chen, C. F. Chen, W. Lee, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells

Matthew A. Kayala, P. Baldi, Yu-Han Chen, 2019, Scientific Reports.

Protein kinase B (PKB/AKT1) formed signaling complexes with mitochondrial proteins and prevented glycolytic energy dysfunction in cultured cardiomyocytes during ischemia-reperfusion injury.

Yu-Han Chen, Yumay Chen, H. Leu, 2014, Endocrinology.

BRCA1 the Versatile Defender: Molecular to Environmental Perspectives

Yumay Chen, Phang-lang Chen, Amy X. Zhong, 2023, International journal of molecular sciences.

Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris*

Yumay Chen, S. Grando, A. Chernyavsky, 2015, The Journal of Biological Chemistry.

Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism

Yu-Han Chen, Yumay Chen, M. Jordan, 2023, Cardiovascular Diabetology.

Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus.

Y. Chen, C. F. Chen, W. Lee, 1999, Proceedings of the National Academy of Sciences of the United States of America.

RTRB-24SYMBIOSIS BETWEEN GBM CELL SUBPOPULATIONS, WITH OR WITHOUT EGFR AMPLIFICATION, IS A NEW MECHANISM OF TUMOR RESISTANCE TO RADIATION THERAPY

Yi-Hong Zhou, Yumay Chen, C. Limoli, 2015 .

Hice1, a Novel Microtubule-Associated Protein Required for Maintenance of Spindle Integrity and Chromosomal Stability in Human Cells

Yumay Chen, Wen-Hwa Lee, Guikai Wu, 2008, Molecular and Cellular Biology.

Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle

Y. Chen, W. Lee, Yumay Chen, 1994, Molecular and cellular biology.