D. Leung

发表

DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs.

Steven J. M. Jones, Mohammad M. Karimi, M. Hirst, 2011, Cell stem cell.

SARS-CoV-2 impacts the transcriptome and epigenome at the maternal-fetal interface in pregnancy

D. Leung, Chi-Chiu Wang, L. Poon, 2022, bioRxiv.

Regulatory roles of three-dimensional structures of topologically associating domains

D. Leung, Qin Cao, Huating Wang, 2022, bioRxiv.

Epigenomic and transcriptomic analysis of chronic inflammatory diseases

D. Leung, Sabrina Ka Man Tam, 2021, Genes & Genomics.

Replication timing maintains the global epigenetic state in human cells

Kyle N. Klein, Peiyao A. Zhao, S. Dalton, 2019, bioRxiv.

Silencing of endogenous retroviruses: when and why do histone marks predominate?

D. Leung, M. Lorincz, 2012, Trends in biochemical sciences.

Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development.

Chia-An Yen, Wei Xie, D. Leung, 2016, Molecular cell.

Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing

F. Rossi, P. Goyal, I. Maksakova, 2011, Proceedings of the National Academy of Sciences.

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

H. Kimura, I. Maksakova, D. Leung, 2010, Nature.

DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

D. Schübeler, Fabio Mohn, I. Maksakova, 2008, The EMBO journal.

Mouse strain-specific polymorphic provirus functions as cis-regulatory element leading to epigenomic and transcriptomic variations

D. Leung, Ah Young Lee, Xuemeng Zhou, 2021, Nature Communications.

Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.

Yan Huang, Thomas Lücke, Joanna Lubieniecka, 2012, Human molecular genetics.

Transcriptional silencing of endogenous retroviruses : interplay between histone H3K9 methylation and DNA methylation

D. Leung, 2011 .

G9a Plays Distinct Roles in Maintaining DNA Methylation, Retrotransposon Silencing, and Chromatin Looping.

Kevin Y. Yip, D. Leung, Qin Cao, 2020, Cell reports.

Title Proviral silencing in embryonic stem cells requires the histonemethyltransferase ESET

H. Kimura, I. Maksakova, D. Leung, 2016 .

Targeting Epigenetic Modifiers for Cancer Treatments

D. Leung, C. Chee, 2018, Current Pharmacology Reports.

Single-cell analysis reveals transcriptomic and epigenomic impacts on the maternal–fetal interface following SARS-CoV-2 infection

D. Leung, L. Poon, S. Moungmaithong, 2023, Nature Cell Biology.

Regulatory roles of three-dimensional structures of chromatin domains

D. Leung, Qin Cao, Huating Wang, 2023, bioRxiv.

DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs.

Mohammad M. Karimi, M. Hirst, M. Bilenky, 2011, Cell stem cell.

A unified framework for integrative study of heterogeneous gene regulatory mechanisms

A. Cheng, Chao Cheng, D. Leung, 2020, Nature Machine Intelligence.

Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development.

Wei Xie, D. Leung, Shaorong Gao, 2016, Molecular cell.

Replication timing maintains the global epigenetic state in human cells

Kyle N. Klein, Peiyao A. Zhao, S. Dalton, 2019, Science.

DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

D. Schübeler, Fabio Mohn, I. Maksakova, 2008, The EMBO journal.

DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response

K. Herrup, D. Leung, Xuan Song, 2021, The Journal of Neuroscience.