A. Depaoli-Roach

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Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry.

Matthew S. Gentry, Lyndsay E A Young, Corey O. Brizzee, 2020, Carbohydrate polymers.

Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase

A. Fox, A. Depaoli-Roach, M. Marshall, 2003, BMC Neuroscience.

Distinctive Regulatory and Metabolic Properties of Glycogen-targeting Subunits of Protein Phosphatase-1 (PTG, GL, GM/RGl) Expressed in Hepatocytes*

H. Berman, P. B. Jensen, C. Newgard, 2000, The Journal of Biological Chemistry.

Reversal of Diet-induced Glucose Intolerance by Hepatic Expression of a Variant Glycogen-targeting Subunit of Protein Phosphatase-1*

C. Newgard, A. Depaoli-Roach, R. Gasa, 2002, The Journal of Biological Chemistry.

Structural Basis for Regulation of Protein Phosphatase 1 by Inhibitor-2*

Marc S. Cortese, Jie Yang, A. Dunker, 2007, Journal of Biological Chemistry.

CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase

M. Goebl, A. Stapleton, J. Pringle, 1991, Molecular and cellular biology.

Isoform differences in substrate recognition by glycogen synthase kinases 3 alpha and 3 beta in the phosphorylation of phosphatase inhibitor 2.

A. Depaoli-Roach, P. Roach, I. Park, 1994, Biochemistry.

Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene.

A. Depaoli-Roach, P. Roach, T. A. Hardy, 1990, The Journal of biological chemistry.

Yeast casein kinase I homologues: an essential gene pair.

L. C. Robinson, C. Kung, M. Goebl, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.

L. C. Robinson, P. Graves, M. Cobb, 1995, The Journal of biological chemistry.

Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.

Robert A. Harris, A. Depaoli-Roach, Pengfei Wu, 2006, The Biochemical journal.

Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle.

J. Maller, A. Depaoli-Roach, D. H. Walker, 1992, Molecular biology of the cell.

Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes

P. Magistretti, A. Depaoli-Roach, P. Roach, 2016, IBRO reports.

Molecular cloning and expression of the regulatory (RG1) subunit of the glycogen-associated protein phosphatase.

A. Depaoli-Roach, K. Swiderek, P. M. Tang, 1991, The Journal of biological chemistry.

Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice*

O. McGuinness, A. Depaoli-Roach, P. Roach, 2010, The Journal of Biological Chemistry.

Regulation of Both Glycogen Synthase and PHAS-I by Insulin in Rat Skeletal Muscle Involves Mitogen-activated Protein Kinase-independent and Rapamycin-sensitive Pathways (*)

A. Depaoli-Roach, A. Saltiel, J. Lawrence, 1996, The Journal of Biological Chemistry.

Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.

A. Depaoli-Roach, P. Roach, T. Hurley, 2017, Biochemistry.

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

A. Depaoli-Roach, P. Roach, N. Morral, 2017, The Journal of Biological Chemistry.

Structure and chromosomal localization of the human glycogenin-2 gene GYG2.

H. Zong, A. Depaoli-Roach, P. Roach, 2000, Gene.

Characterization of rabbit skeletal muscle glycogenin. Tyrosine 194 is essential for function.

A. Depaoli-Roach, P. Roach, Y. Cao, 1993, Journal of Biological Chemistry.

Rabbit skeletal muscle glycogenin. Molecular cloning and production of fully functional protein in Escherichia coli.

A. Depaoli-Roach, P. Roach, Youjia Cao, 1992, The Journal of biological chemistry.

Structural basis for glucose-6-phosphate activation of glycogen synthase

A. Depaoli-Roach, P. Roach, T. Hurley, 2010, Proceedings of the National Academy of Sciences.

Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.

A. Depaoli-Roach, P. Roach, Q. Wang, 1994, The Journal of biological chemistry.

Targeting Pathogenic Lafo ra Bodies in Lafora Disease Using an Antibody-Enzyme Fusion Graphical

Matthew S. Gentry, A. Depaoli-Roach, P. Roach, 2019 .

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver*

A. Depaoli-Roach, P. Roach, C. Hoppel, 2014, The Journal of Biological Chemistry.

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.

R. Lefkowitz, A. Depaoli-Roach, J. Pitcher, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Gene structure and expression of the targeting subunit, RGL, of the muscle-specific glycogen-associated type 1 protein phosphatase, PP1G.

A. Depaoli-Roach, Y. Suzuki, C. Lannér, 2001, Archives of biochemistry and biophysics.

Mechanism of Receptor Kinase Action on Membrane Protein Recycling a

A. Depaoli-Roach, P. Roach, R. Davis, 1986, Annals of the New York Academy of Sciences.

Glycogen metabolism and signal transduction in mammals and yeast.

P. Graves, A. Depaoli-Roach, P. Roach, 1991, Advances in enzyme regulation.

Primary structure of rabbit skeletal muscle glycogen synthase deduced from cDNA clones

R. Fletterick, A. Depaoli-Roach, P. Roach, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Novel regulation of cardiac force‐frequency relation by CREM (cAMP response element modulator)

D. Kass, P. Sassone-Corsi, A. Depaoli-Roach, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Native cytosolic protein phosphatase‐1 (PP‐1S) containing modulator (inhibitor‐2) is an active enzyme

M. Bollen, A. Depaoli-Roach, W. Stalmans, 1994, FEBS letters.

Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2.

A. Depaoli-Roach, W. Schmitz, H. Baba, 2005, Cardiovascular research.

Pathologic gene network rewiring implicates PPP1R3A as a central cardioprotective factor in pressure overload heart failure

Kevin S. Smith, H. Hakonarson, Mingyao Li, 2016, bioRxiv.

Liver Gluconeogenic Gene Expression in Mouse Regulate Glycogen Synthesis and Protein-1 ( SREBP-1 ) Is Required to Sterol Regulatory Element-binding Gene Regulation :

A. Depaoli-Roach, P. Roach, C. Hoppel, 2014 .

Exercise Capacity of Mice Genetically Lacking Muscle Glycogen Synthase

A. Depaoli-Roach, P. Roach, B. Thurberg, 2005, Journal of Biological Chemistry.

Discovery and development of small-molecule inhibitors of glycogen synthase.

D. Watt, A. Depaoli-Roach, P. Roach, 2020, Journal of medicinal chemistry.

Mice with elevated muscle glycogen stores do not have improved exercise performance.

A. Depaoli-Roach, P. Roach, B. Thurberg, 2005, Biochemical and biophysical research communications.

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

P. Kirchhof, A. Depaoli-Roach, W. Schmitz, 2008, American journal of physiology. Heart and circulatory physiology.

CHAPTER 103 – Protein Phosphatase 1 Binding Proteins

A. Depaoli-Roach, 2003 .

In vivo regulation of protein kinase C by trans-phosphorylation followed by autophosphorylation.

A. Newton, A. Depaoli-Roach, E. Dutil, 1994, The Journal of biological chemistry.

Novel method for detection of glycogen in cells

A. Depaoli-Roach, P. Roach, A. V. Skurat, 2017, Glycobiology.

Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon.

A. Depaoli-Roach, P. Roach, C. Ciudad, 1984, European journal of biochemistry.

Determination of mammalian glycogen synthase phosphatase activity.

A. Depaoli-Roach, P. Roach, Jong-Hwa Kim, 2003, Methods in enzymology.

Heparin-activated protein kinase from rabbit muscle: relationship to enzymes of the glycogen synthase kinase-3 category.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1986, Archives of biochemistry and biophysics.

Multiple phosphorylation sites of rat liver glycogen synthase.

A. Depaoli-Roach, P. Roach, M. Camici, 1986, Biochimica et biophysica acta.

Glycogen synthase kinases. Classification of a rabbit liver casein and glycogen synthase kinase (casein kinase-1) as a distinct enzyme.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis.

C. Hagedorn, P. Graves, A. Depaoli-Roach, 1993, The Journal of biological chemistry.

Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2.

A. Depaoli-Roach, P. Roach, I. Park, 1994, The Journal of biological chemistry.

Mechanisms of multisite phosphorylation and inactivation of rabbit muscle glycogen synthase.

A. Depaoli-Roach, P. Roach, W. Zhang, 1993, Archives of biochemistry and biophysics.

Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Evidence for interactions among phosphorylation sites and the resolution of electrophoretically distinct forms of the subunit.

A. Depaoli-Roach, P. Roach, J. Lawrence, 1983, The Journal of biological chemistry.

Phosphorylation and Activation of the ATP-Mg-dependent Protein Phosphatase by the Mitogen-activated Protein Kinase (*)

K. Guan, A. Depaoli-Roach, P. Roach, 1995, The Journal of Biological Chemistry.

Metabolic effects of proglycosyn.

R. Harris, A. Depaoli-Roach, T. Stephens, 1992, Archives of biochemistry and biophysics.

Interaction of the insulin receptor kinase with serine/threonine kinases in vitro

C. Kahn, M. White, H. Haring, 1985, Journal of cellular biochemistry.

ENZYMATIC REGULATION OF GLYCOGEN SYNTHESIS: PHOSPHORYLATION OF GLYCOGEN SYNTHASE BY CYCLIC AMP-DEPENDENT PROTEIN KINASE, CYCLIC AMP-INDEPENDENT SYNTHASE KINASE AND PHOSPHORYLASE KINASE1

A. Depaoli-Roach, P. Roach, J. Larner, 1980 .

Identification of phosphorylation sites in peptides using a gas-phase sequencer.

A. Depaoli-Roach, P. Roach, M. Hermodson, 1988, Analytical biochemistry.

Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A

A. Lewellyn, J. Maller, A. Depaoli-Roach, 2009, Cell cycle.

Hormonal control of glycogen synthase in rat hemidiaphragms. Effects of insulin and epinephrine on the distribution of phosphate between two cyanogen bromide fragments.

A. Depaoli-Roach, P. Roach, J. Lawrence, 1983, The Journal of biological chemistry.

Phosphorylation of glycogen synthase and of the beta subunit of eukaryotic initiation factor two by a common protein kinase.

A. Depaoli-Roach, P. Roach, G. Kramer, 1981, The Journal of biological chemistry.

Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1981, The Journal of biological chemistry.

Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro.

A. Depaoli-Roach, P. Roach, J. Larner, 1979, The Journal of biological chemistry.

Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates.

A. Depaoli-Roach, P. Roach, J. Larner, 1979, The Journal of biological chemistry.

Insulin action inhibits insulin-like growth factor-II (IGF-II) receptor phosphorylation in H-35 hepatoma cells. IGF-II receptors isolated from insulin-treated cells exhibit enhanced in vitro phosphorylation by casein kinase II.

A. Depaoli-Roach, P. Roach, M. Czech, 1988, The Journal of biological chemistry.

Rabbit liver glycogen synthase kinases. Characterization of a protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1982, The Journal of biological chemistry.

Inhibition of branched chain alpha-ketoacid dehydrogenase kinase activity by alpha-chloroisocaproate.

R. Harris, A. Depaoli-Roach, R. Paxton, 1982, The Journal of biological chemistry.

Phosphorylation of phosphoprotein phosphatase inhibitor-2 (I-2) in rat fat cells.

A. Depaoli-Roach, J. Lawrence, J. Hiken, 1988, Biochemical and biophysical research communications.

Novel heparin‐activated protein kinase activity in rabbit skeletal muscle

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1985, FEBS letters.

Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle.

A. Depaoli-Roach, P. Roach, 1982, Archives of biochemistry and biophysics.

Phosphorylation of rabbit liver glycogen synthase by multiple protein kinases.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Glycogen metabolism in tissues from a mouse model of Lafora disease.

A. Depaoli-Roach, P. Roach, H. Lohi, 2007, Archives of biochemistry and biophysics.

Phosphorylation of glycogen synthase by a bovine thymus protein-tyrosine kinase, p40.

R. Geahlen, A. Depaoli-Roach, P. Roach, 1988, Biochemical and biophysical research communications.

Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of persistent pain

A. Depaoli-Roach, Anna M. Hagenston, T. Fleming, 2022, bioRxiv.

Protein Phosphatase 1 Binding Proteins

A. Depaoli-Roach, 2010 .

Glucose metabolism in mice lacking muscle glycogen synthase.

A. Depaoli-Roach, P. Roach, B. A. Pederson, 2005, Diabetes.

Decreased Protein Phosphatase 2A Activity in Hippocampal Long‐Term Potentiation

D. Muller, K. Fukunaga, A. Depaoli-Roach, 2000, Journal of neurochemistry.

Purification and characterization of a rabbit liver calmodulin-dependent protein kinase able to phosphorylate glycogen synthase.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1982, Journal of Biological Chemistry.

Cyclin G2 Associates with Protein Phosphatase 2A Catalytic and Regulatory B′ Subunits in Active Complexes and Induces Nuclear Aberrations and a G1/S Phase Cell Cycle Arrest*

A. Depaoli-Roach, M. Horne, David A Bennin, 2002, The Journal of Biological Chemistry.

Protein kinase A modulates an endogenous calcium channel, but not the calcium‐activated chloride channel, in Xenopus oocytes

A. Depaoli-Roach, Y. Wang, Lei Yu, 1993, FEBS letters.

Generation by insulin of a chemical mediator that controls protein phosphorylation and dephosphorylation.

K. Cheng, A. Depaoli-Roach, L. Huang, 1979, Science.

PKC-α regulates cardiac contractility and propensity toward heart failure

T. Hewett, A. Nairn, J. Bibb, 2004, Nature Medicine.

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism*

C. Wells, A. Depaoli-Roach, P. Roach, 2010, The Journal of Biological Chemistry.

PTG Depletion Removes Lafora Bodies and Rescues the Fatal Epilepsy of Lafora Disease

C. Ackerley, M. Cortez, A. Depaoli-Roach, 2011, PLoS genetics.

Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2013, Proceedings of the National Academy of Sciences.

Phosphate incorporation during glycogen synthesis and Lafora disease.

M. Ishihara, P. Azadi, Christopher J. Contreras, 2011, Cell metabolism.

Phosphorylase kinase from rabbit skeletal muscle: Phosphorylation of κ-casein

A. Depaoli-Roach, P. Roach, E. Bingham, 1981 .

Selective phosphorylation of human DNA methyltransferase by protein kinase C

A. Depaoli-Roach, P. Roach, Steven S. Smith, 1986, FEBS letters.

Targeting pathogenic Lafora bodies in Lafora disease using an antibody-enzyme fusion

Matthew S. Gentry, A. Depaoli-Roach, P. Roach, 2019, bioRxiv.

Protein Degradation and Quality Control in Cells from Laforin and Malin Knockout Mice*

A. Depaoli-Roach, P. Roach, Dyann M. Segvich, 2014, The Journal of Biological Chemistry.

Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo

A. Delgado-Escueta, A. Depaoli-Roach, P. Roach, 2007, Proceedings of the National Academy of Sciences.

Glycogen Metabolism and Lafora Disease

A. Depaoli-Roach, P. Roach, 2013 .

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2010, The Journal of Biological Chemistry.

Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2008, Journal of Biological Chemistry.

GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease

A. Depaoli-Roach, P. Roach, Peixiang Wang, 2020, Annals of clinical and translational neurology.

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Michael J. Gloudemans, Kevin S. Smith, H. Hakonarson, 2019, Nature Communications.

A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice

S. O’Rahilly, G. Shulman, N. Wareham, 2008, PLoS medicine.

A Prevalent Variant in PPP 1 R 3 A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice

S. O’Rahilly, G. Shulman, N. Wareham, 2008 .

Serine/threonine protein phosphatases in the control of cell function.

S. Durbin, A. Depaoli-Roach, A. Verin, 1994, Advances in enzyme regulation.

Binding of CTP:phosphocholine cytidylyltransferase to lipid vesicles: diacylglycerol and enzyme dephosphorylation increase the affinity for negatively charged membranes.

A. Depaoli-Roach, R. Cornell, R. Arnold, 1997, Biochemistry.

High Complexity in the Expression of the B′ Subunit of Protein Phosphatase 2A0

S. Durbin, A. Depaoli-Roach, É. Bakó, 1996, The Journal of Biological Chemistry.

Glycogen and its metabolism: some new developments and old themes.

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2012, The Biochemical journal.

Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen*

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2011, The Journal of Biological Chemistry.

Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase.

A. Depaoli-Roach, I. Park, 1994, The Journal of biological chemistry.

Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F A/GSK-3 and casein kinase II (PC0.7).

A. Depaoli-Roach, 1984, The Journal of biological chemistry.

Glucose Metabolism in Mice Lacking Muscle Glycogen

A. Depaoli-Roach, P. Roach, Jill M. Schroeder, 2005 .

Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain.

M. Mumby, A. Depaoli-Roach, A. Verin, 1994, Biochemistry.

Saccharomyces cerevisiae Homologs of Mammalian B and B′ Subunits of Protein Phosphatase 2A Direct the Enzyme to Distinct Cellular Functions*

A. Depaoli-Roach, Y. Zhao, R. Zitomer, 1997, The Journal of Biological Chemistry.

Dephosphorylation of myosin by the catalytic subunit of a type-2 phosphatase produces relaxation of chemically skinned uterine smooth muscle.

A. Depaoli-Roach, D. Hathaway, J. Haeberle, 1985, Journal of Biological Chemistry.

Abnormal Cardiac Development in the Absence of Heart Glycogen

A. Depaoli-Roach, P. Roach, W. Shou, 2004, Molecular and Cellular Biology.

Type 1 Phosphatase, a Negative Regulator of Cardiac Function

Andrew N. Carr, P. Greengard, P. Allen, 2002, Molecular and Cellular Biology.

Dephosphorylation of Sp1 by Protein Phosphatase 1 Is Involved in the Glucose-mediated Activation of the Acetyl-CoA Carboxylase Gene*

A. Depaoli-Roach, Shaoying Zhang, S. Daniel, 1996, The Journal of Biological Chemistry.

Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1

Andrew N. Carr, E. Heist, J. Guerrero, 2005, Circulation research.

Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility.

A. Depaoli-Roach, H. Rockman, L. Field, 1998, Journal of molecular and cellular cardiology.

PKC-alpha regulates cardiac contractility and propensity toward heart failure.

T. Hewett, A. Nairn, J. Bibb, 2004, Nature medicine.

Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL

A. Depaoli-Roach, A. Scrimgeour, J. Lawrence, 2001, Molecular and Cellular Biology.

The Muscle-specific Protein Phosphatase PP1G/RGL(GM) Is Essential for Activation of Glycogen Synthase by Exercise*

A. Depaoli-Roach, S. Dufresne, L. Goodyear, 2001, The Journal of Biological Chemistry.

Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease*

M. Ishihara, P. Azadi, Christopher J. Contreras, 2014, The Journal of Biological Chemistry.

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.

C. V. Vander Kooi, Matthew S. Gentry, Jéssica K A Macêdo, 2021, Cell metabolism.

Phosphoserine as a recognition determinant for glycogen synthase kinase-3: phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1.

A. Depaoli-Roach, P. Roach, Y. H. Wang, 1988, Archives of biochemistry and biophysics.

Interaction of Inhibitor-2 with the Catalytic Subunit of Type 1 Protein Phosphatase

Jie Yang, A. Depaoli-Roach, T. Hurley, 2000, The Journal of Biological Chemistry.

Ca2+-stimulated phosphorylation of muscle glycogen synthase by phosphorylase b kinase.

A. Depaoli-Roach, P. Roach, J. Larner,, 1978, Journal of cyclic nucleotide research.

Recombinant rabbit muscle casein kinase I α is inhibited by heparin and activated by polylysine

K. Longenecker, P. Graves, A. Depaoli-Roach, 1992 .

Fluorescence studies on the interaction of inhibitor 2 and okadaic acid with the catalytic subunit of type 1 phosphoprotein phosphatases.

A. Depaoli-Roach, W. Merlevede, I. Park, 1991, Biochemistry.

A Protein Phosphatase-1γ1 Isoform Selectivity Determinant in Dendritic Spine-associated Neurabin*

R. Colbran, A. Depaoli-Roach, L. Carmody, 2004, Journal of Biological Chemistry.

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.

C. Wells, A. Depaoli-Roach, P. Roach, 2011, The Journal of Biological Chemistry.

Cellular Mechanisms Regulating Protein Phosphatase-1 A KEY FUNCTIONAL INTERACTION BETWEEN INHIBITOR-2 AND THE TYPE 1 PROTEIN PHOSPHATASE CATALYTIC SUBUNIT*

Jie Yang, A. Nairn, S. Shenolikar, 2000 .

Basis for MAP4 Dephosphorylation-related Microtubule Network Densification in Pressure Overload Cardiac Hypertrophy*

A. Depaoli-Roach, A. Shunmugavel, D. Menick, 2010, The Journal of Biological Chemistry.

Incorporation of phosphate into glycogen by glycogen synthase.

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2016, Archives of biochemistry and biophysics.

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity.

C. Worby, Matthew S. Gentry, A. Depaoli-Roach, 2012, Human molecular genetics.

Relationship between glycogen accumulation and the laforin dual specificity phosphatase.

A. Depaoli-Roach, P. Roach, N. Raben, 2006, Biochemical and biophysical research communications.

Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells.

T. Sugimura, A. Depaoli-Roach, M. Nagao, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Calcium and calmodulin activation of muscle phosphorylase kinase

A. Depaoli-Roach, P. Roach, J. Gibbs, 1979, FEBS Letters.

Phosphorylation-dependent Inhibition of Protein Phosphatase-1 by G-substrate

M. Uhler, A. Depaoli-Roach, D. Gamm, 1999, The Journal of Biological Chemistry.

Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2015, The Journal of Biological Chemistry.

Cellular Mechanisms Regulating Protein Phosphatase-1

Jie Yang, A. Nairn, S. Shenolikar, 2000, The Journal of Biological Chemistry.

Phosphoprotein phosphatase inhibitor‐2 is phosphorylated at both serine and threonine residues in mouse diaphragm

A. Depaoli-Roach, F. Lee, Anna A. DePaoli-Roach, 1985, FEBS letters.

Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Pathologic gene network rewiring implicates PPP1R3A as a central cardioprotective factor in pressure overload heart failure

Kevin S. Smith, H. Hakonarson, Mingyao Li, 2016, bioRxiv.

Phosphoprotein phosphatase inhibitor-2. Identification as a species of molecular weight 31,000 in rabbit muscle, liver, and other tissues.

A. Depaoli-Roach, P. Roach, 1985, The Journal of biological chemistry.

Initiation of glycogen synthesis. Control of glycogenin by glycogen phosphorylase.

A. Depaoli-Roach, P. Roach, A. V. Skurat, 1993, The Journal of biological chemistry.

Phosphorylation of glycogen synthase by the Ca2+- and phospholipid-activated protein kinase (protein kinase C).

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1984, The Journal of biological chemistry.

and glycogen synthase in human skeletal muscle Insulin and exercise differentially regulate PI3-kinase

A. Depaoli-Roach, S. Dufresne, L. Goodyear, 2015 .

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

A. Depaoli-Roach, P. Roach, N. Morral, 2017, The Journal of Biological Chemistry.

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

P. Kirchhof, A. Depaoli-Roach, W. Schmitz, 2008, American journal of physiology. Heart and circulatory physiology.

The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.

N. Fastman, A. Depaoli-Roach, P. Roach, 2022, Cell reports.