P. Roach

R. Fletterick, A. Depaoli-Roach, P. Roach, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hepatic Glucose Metabolism in Late Pregnancy

P. Roach, Phillip E. Williams, Ben Farmer, 2013, Diabetes.

Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition.

K. Longenecker, P. Roach, T. Hurley, 1996, Journal of molecular biology.

Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase.

P. Roach, H. Flotow, 1989, The Journal of biological chemistry.

Liver Gluconeogenic Gene Expression in Mouse Regulate Glycogen Synthesis and Protein-1 ( SREBP-1 ) Is Required to Sterol Regulatory Element-binding Gene Regulation :

A. Depaoli-Roach, P. Roach, C. Hoppel, 2014 .

Exercise Capacity of Mice Genetically Lacking Muscle Glycogen Synthase

A. Depaoli-Roach, P. Roach, B. Thurberg, 2005, Journal of Biological Chemistry.

Lafora disease offers a unique window into neuronal glycogen metabolism

J. Serratosa, Matthew S. Gentry, P. Roach, 2018, The Journal of Biological Chemistry.

Discovery and development of small-molecule inhibitors of glycogen synthase.

D. Watt, A. Depaoli-Roach, P. Roach, 2020, Journal of medicinal chemistry.

Mice with elevated muscle glycogen stores do not have improved exercise performance.

A. Depaoli-Roach, P. Roach, B. Thurberg, 2005, Biochemical and biophysical research communications.

Glucose control of rabbit skeletal muscle glycogenin expressed in COS cells.

P. Roach, Y. Cao, A. V. Skurat, 1993, The Journal of biological chemistry.

Insulin resistance in denervated skeletal muscle. Inability of insulin to stimulate dephosphorylation of glycogen synthase in denervated rat epitrochlearis muscles.

P. Roach, J. Lawrence, R. Smith, 1988, The Journal of biological chemistry.

Glycogen synthase: activation by insulin and effect of transgenic overexpression in skeletal muscle.

P. Roach, J. Lawrence, J. Manchester, 1997, Biochemical Society transactions.

Insulin control of glycogen synthesis.

P. Roach, J. Larner, J. Lawrence, 1978, Advances in cyclic nucleotide research.

Structure and Molecular Mechanism of a Nucleobase–Cation–Symport-1 Family Transporter

Shunsuke Yajima, Simon G. Patching, So Iwata, 2008, Science.

Mechanism of glycogenin self-glucosylation.

L. Steinrauf, P. Roach, Y. Cao, 1995, Archives of biochemistry and biophysics.

Role of acidic residues as substrate determinants for casein kinase I.

P. Roach, H. Flotow, Peter J. Roach, 1991, The Journal of biological chemistry.

Inactivation of rabbit muscle glycogen synthase by glycogen synthase kinase-3. Dominant role of the phosphorylation of Ser-640 (site-3a).

P. Roach, Y. Wang, 1993, The Journal of biological chemistry.

Putative Yeast Homolog of Glycogen Synthase

P. Roach, Robert B. Johnson, J. Puziss, 2022 .

Initiation of Glycogen Synthesis in Yeast REQUIREMENT OF MULTIPLE TYROSINE RESIDUES FOR FUNCTION OF THE SELF-GLUCOSYLATING Glg PROTEINS IN VIVO*

P. Roach, J. Mu, Christine A. Cheng, 1996 .

Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled.

M. Goebl, P. Roach, T. A. Hardy, 1991, The Journal of biological chemistry.

Glucose-6-P Control of Glycogen Synthase Phosphorylation in Yeast*

P. Roach, W. Wilson, Dongqing Huang, 1997, The Journal of Biological Chemistry.

Phosphorylation of Sites 3a and 3b (Ser640 and Ser644) in the Control of Rabbit Muscle Glycogen Synthase(*)

P. Roach, A. V. Skurat, 1995, The Journal of Biological Chemistry.

Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins*

S. Howell, A. Aitken, P. Roach, 2001, The Journal of Biological Chemistry.

Novel method for detection of glycogen in cells

A. Depaoli-Roach, P. Roach, A. V. Skurat, 2017, Glycobiology.

Structure and Molecular Mechanism of a Nucleobase–Cation–Symport-1 Family Transporter

E. Carpenter, S. Yajima, S. Iwata, 2008, Science.

A Soluble Guanylate Cyclase–Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo

P. Roach, A. Cherrington, D. Neal, 2010, Diabetes.

Glycogen synthase sensitivity to insulin and glucose-6-phosphate is mediated by both NH2- and COOH-terminal phosphorylation sites.

P. Roach, A. V. Skurat, A. Dietrich, 2000, Diabetes.

12 Liver Glycogen Synthase

P. Roach, 1986 .

Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon.

A. Depaoli-Roach, P. Roach, C. Ciudad, 1984, European journal of biochemistry.

Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties.

P. Roach, J. Larner, Y. Takeda, 1976, The Journal of biological chemistry.

Determination of mammalian glycogen synthase phosphatase activity.

A. Depaoli-Roach, P. Roach, Jong-Hwa Kim, 2003, Methods in enzymology.

Heparin-activated protein kinase from rabbit muscle: relationship to enzymes of the glycogen synthase kinase-3 category.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1986, Archives of biochemistry and biophysics.

Multiple phosphorylation sites of rat liver glycogen synthase.

A. Depaoli-Roach, P. Roach, M. Camici, 1986, Biochimica et biophysica acta.

Glycogen synthase kinases. Classification of a rabbit liver casein and glycogen synthase kinase (casein kinase-1) as a distinct enzyme.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers.

P. Roach, S. Freedman, M. A. Magee, 1993, International journal of cardiology.

Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis.

C. Hagedorn, P. Graves, A. Depaoli-Roach, 1993, The Journal of biological chemistry.

John C. Lawrence, Jr. (1949–2006)

P. Roach, 2007 .

Use of a synthetic peptide as a selective substrate for glycogen synthase kinase 3.

P. Roach, Q. Wang, C. Fiol, 1994, Analytical biochemistry.

Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2.

A. Depaoli-Roach, P. Roach, I. Park, 1994, The Journal of biological chemistry.

Mechanisms of multisite phosphorylation and inactivation of rabbit muscle glycogen synthase.

A. Depaoli-Roach, P. Roach, W. Zhang, 1993, Archives of biochemistry and biophysics.

Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Evidence for interactions among phosphorylation sites and the resolution of electrophoretically distinct forms of the subunit.

A. Depaoli-Roach, P. Roach, J. Lawrence, 1983, The Journal of biological chemistry.

Phosphorylation and Activation of the ATP-Mg-dependent Protein Phosphatase by the Mitogen-activated Protein Kinase (*)

K. Guan, A. Depaoli-Roach, P. Roach, 1995, The Journal of Biological Chemistry.

Stabilization of glycogen stores and stimulation of glycogen synthesis in hepatocytes by phenacyl imidazolium compounds.

R. Harris, P. Roach, T. Stephens, 1989, The Journal of biological chemistry.

Interaction of the insulin receptor kinase with serine/threonine kinases in vitro

C. Kahn, M. White, H. Haring, 1985, Journal of cellular biochemistry.

Surprises of genetic engineering

S. Dimauro, P. Roach, N. Raben, 2001, Neurology.

Covalent phosphorylation in the regulation of glycogen synthase activity

P. Roach, J. Larner, J. Larner,, 1977, Molecular and Cellular Biochemistry.

Studies on Glycogen Synthase and Its Control by Hormones

F. Murad, H. Brewer, G. Brooker, 1974 .

ENZYMATIC REGULATION OF GLYCOGEN SYNTHESIS: PHOSPHORYLATION OF GLYCOGEN SYNTHASE BY CYCLIC AMP-DEPENDENT PROTEIN KINASE, CYCLIC AMP-INDEPENDENT SYNTHASE KINASE AND PHOSPHORYLASE KINASE1

A. Depaoli-Roach, P. Roach, J. Larner, 1980 .

Identification of phosphorylation sites in peptides using a gas-phase sequencer.

A. Depaoli-Roach, P. Roach, M. Hermodson, 1988, Analytical biochemistry.

Identification of Phosphorylated Amino Acid Residues During Gas Phase Sequencing

P. Roach, Yuhuan Wang, M. Hermodson, 1987 .

Novel Saccharomyces cerevisiae gene, MRK1, encoding a putative protein kinase with similarity to mammalian glycogen synthase kinase-3 and Drosophila Zeste-White3/Shaggy.

P. Roach, T. A. Hardy, D. Wu, 1995, Biochemical and biophysical research communications.

Interaction between glycogenin and glycogen synthase.

P. Roach, A. V. Skurat, A. Dietrich, 2006, Archives of biochemistry and biophysics.

Hormonal control of glycogen metabolism.

F. Murad, G. Brooker, P. Roach, 1979, Advances in experimental medicine and biology.

Hormonal control of glycogen synthase in rat hemidiaphragms. Effects of insulin and epinephrine on the distribution of phosphate between two cyanogen bromide fragments.

A. Depaoli-Roach, P. Roach, J. Lawrence, 1983, The Journal of biological chemistry.

Phosphorylation of glycogen synthase and of the beta subunit of eukaryotic initiation factor two by a common protein kinase.

A. Depaoli-Roach, P. Roach, G. Kramer, 1981, The Journal of biological chemistry.

Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1981, The Journal of biological chemistry.

Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro.

A. Depaoli-Roach, P. Roach, J. Larner, 1979, The Journal of biological chemistry.

Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates.

A. Depaoli-Roach, P. Roach, J. Larner, 1979, The Journal of biological chemistry.

Muscle glycogen synthase in vivo state:

P. Roach, J. Larner, M. Rosell-Perez, 1977, FEBS letters.

Insulin action inhibits insulin-like growth factor-II (IGF-II) receptor phosphorylation in H-35 hepatoma cells. IGF-II receptors isolated from insulin-treated cells exhibit enhanced in vitro phosphorylation by casein kinase II.

A. Depaoli-Roach, P. Roach, M. Czech, 1988, The Journal of biological chemistry.

Rabbit liver glycogen synthase kinases. Characterization of a protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1982, The Journal of biological chemistry.

Novel heparin‐activated protein kinase activity in rabbit skeletal muscle

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1985, FEBS letters.

Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle.

A. Depaoli-Roach, P. Roach, 1982, Archives of biochemistry and biophysics.

Multiple mechanisms for the phosphorylation of C-terminal regulatory sites in rabbit muscle glycogen synthase expressed in COS cells.

P. Roach, A. V. Skurat, 1996, The Biochemical journal.

Phosphorylation of rabbit liver glycogen synthase by multiple protein kinases.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1.

C. Wells, P. Roach, Sixin Jiang, 2011, Biochemical and biophysical research communications.

Control of glycogen synthase by hierarchal protein phosphorylation

P. Roach, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glycogen metabolism in tissues from a mouse model of Lafora disease.

A. Depaoli-Roach, P. Roach, H. Lohi, 2007, Archives of biochemistry and biophysics.

Glycogen synthase turnover and phosphorylation in rat H4IIE hepatoma cells.

P. Roach, D. J. Armstrong, 1989, Archives of biochemistry and biophysics.

Phosphorylation of glycogen synthase by a bovine thymus protein-tyrosine kinase, p40.

R. Geahlen, A. Depaoli-Roach, P. Roach, 1988, Biochemical and biophysical research communications.

Effect of partial tryptic proteolysis on the kinetic properties of rabbit muscle glycogen synthase.

P. Roach, J. Guinovart, A. Salavert, 1979, Biochimica et biophysica acta.

Regulation of glycogen synthase: a relation of enzymic properties with biological function

P. Roach, J. Larner, J. Larner,, 1976 .

Glycogen and Starch

S. Zeeman, P. Roach, 2016 .

Hierarchal phosphorylation of proteins

P. Roach, C. Fiol, 2007 .

Glucose metabolism in mice lacking muscle glycogen synthase.

A. Depaoli-Roach, P. Roach, B. A. Pederson, 2005, Diabetes.

Purification and characterization of a rabbit liver calmodulin-dependent protein kinase able to phosphorylate glycogen synthase.

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1982, The Journal of biological chemistry.

Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin.

P. Roach, B. Gibbons, T. Hurley, 2002, Journal of molecular biology.

Liver isozyme of rabbit glycogen synthase. Amino acid sequences surrounding phosphorylation sites recognized by cyclic AMP-dependent protein kinase.

P. Roach, M. Hermodson, A. Bell, 1986, The Journal of biological chemistry.

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism*

C. Wells, A. Depaoli-Roach, P. Roach, 2010, The Journal of Biological Chemistry.

Inhibiting glycogen synthesis prevents lafora disease in a mouse model

C. Ackerley, P. Frankland, J. Epp, 2013, Annals of neurology.

PTG Depletion Removes Lafora Bodies and Rescues the Fatal Epilepsy of Lafora Disease

C. Ackerley, M. Cortez, A. Depaoli-Roach, 2011, PLoS genetics.

Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2013, Proceedings of the National Academy of Sciences.

Phosphate incorporation during glycogen synthesis and Lafora disease.

M. Ishihara, P. Azadi, Christopher J. Contreras, 2011, Cell metabolism.

Uridine diphosphate glucose synthase from calf liver: determinants of enzyme activity in vitro.

D. E. Atkinson, P. Roach, K. R. Warren, 1975, Biochemistry.

Glycogenin-2, a Novel Self-glucosylating Protein Involved in Liver Glycogen Biosynthesis*

P. Roach, J. Mu, A. V. Skurat, 1997, The Journal of Biological Chemistry.

Phosphorylase kinase from rabbit skeletal muscle: Phosphorylation of κ-casein

A. Depaoli-Roach, P. Roach, E. Bingham, 1981 .

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

J. Eeckhoute, C. Dani, S. Lancel, 2019, Cell reports.

Selective phosphorylation of human DNA methyltransferase by protein kinase C

A. Depaoli-Roach, P. Roach, Steven S. Smith, 1986, FEBS letters.

Targeting pathogenic Lafora bodies in Lafora disease using an antibody-enzyme fusion

Matthew S. Gentry, A. Depaoli-Roach, P. Roach, 2019, bioRxiv.

Protein Degradation and Quality Control in Cells from Laforin and Malin Knockout Mice*

A. Depaoli-Roach, P. Roach, Dyann M. Segvich, 2014, The Journal of Biological Chemistry.

Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo

A. Delgado-Escueta, A. Depaoli-Roach, P. Roach, 2007, Proceedings of the National Academy of Sciences.

Glycogen Metabolism and Lafora Disease

A. Depaoli-Roach, P. Roach, 2013 .

Glycogen phosphorylation and Lafora disease.

P. Roach, 2015, Molecular aspects of medicine.

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2010, The Journal of Biological Chemistry.

Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2008, Journal of Biological Chemistry.

GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease

A. Depaoli-Roach, P. Roach, Peixiang Wang, 2020, Annals of clinical and translational neurology.

A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice

S. O’Rahilly, G. Shulman, N. Wareham, 2008, PLoS medicine.

A Prevalent Variant in PPP 1 R 3 A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice

S. O’Rahilly, G. Shulman, N. Wareham, 2008 .

Regulation of glycogen metabolism in yeast and bacteria.

Edurne Baroja-Fernández, F. Muñoz, E. Baroja-Fernández, 2010, FEMS microbiology reviews.

The yeast cyclins Pc16p and Pc17p are involved in the control of glycogen storage by the cyclin‐dependent protein kinase Pho85p

P. Roach, W. Wilson, Zhong Wang, 2001, FEBS letters.

Antagonistic Controls of Autophagy and Glycogen Accumulation by Snf1p, the Yeast Homolog of AMP-Activated Protein Kinase, and the Cyclin-Dependent Kinase Pho85p

P. Roach, W. Wilson, Zhong Wang, 2001, Molecular and Cellular Biology.

Substrate Targeting of the Yeast Cyclin-Dependent Kinase Pho85p by the Cyclin Pcl10p

P. Roach, W. Wilson, Peter J. Roach, 1999, Molecular and Cellular Biology.

Cyclin Partners Determine Pho85 Protein Kinase Substrate Specificity In Vitro and In Vivo: Control of Glycogen Biosynthesis by Pcl8 and Pcl10

L. Moore, J. Moffat, B. Andrews, 1998, Molecular and Cellular Biology.

Regulationofglycogenmetabolism inyeast and bacteria

E. Baroja-Fernández, A. Viale, J. Pozueta-Romero, 2010 .

MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3

P. Hieter, P. Roach, T. A. Hardy, 1994, Molecular and cellular biology.

Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice*

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2015, The Journal of Biological Chemistry.

Characterization of Human Glycogenin-2, a Self-glucosylating Initiator of Liver Glycogen Metabolism*

P. Roach, J. Mu, 1998, The Journal of Biological Chemistry.

Phosphate groups as substrate determinants for casein kinase I action.

P. Graves, P. Roach, H. Flotow, 1990, The Journal of biological chemistry.

Multisite and hierarchal protein phosphorylation.

P. Roach, Peter J. Roach, 1991, The Journal of biological chemistry.

Role of COOH-terminal Phosphorylation in the Regulation of Casein Kinase Iδ (*)

P. Graves, P. Roach, P R Graves, 1995, The Journal of Biological Chemistry.

Gain of function AMP‐activated protein kinase γ3 mutation (AMPK γ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation

D. Gerrard, P. Roach, Sungkwon Park, 2016, Physiological reports.

Casein Kinase I and the Classification of Protein Kinases: What’s in a Name?

P. Roach, 1993 .

Yeast PIG Genes: PIG1 Encodes a Putative Type 1 Phosphatase Subunit that Interacts with the Yeast Glycogen Synthase Gsy2p

P. Roach, Dongqing Huang, C. Cheng, 1997, Yeast.

Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers.

P. Roach, J. Lawrence, J. Manchester, 2000, American journal of physiology. Endocrinology and metabolism.

Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3.

P. Roach, P J Roach, Y. Wang, 1987, The Journal of biological chemistry.

Regulation of yeast glycogen phosphorylase by the cyclin-dependent protein kinase Pho85p.

P. Roach, W. Wilson, Zhong Wang, 2005, Biochemical and biophysical research communications.

Glycogen and its metabolism: some new developments and old themes.

A. Depaoli-Roach, P. Roach, V. Tagliabracci, 2012, The Biochemical journal.

Structure-function analysis of GNIP, the glycogenin-interacting protein.

P. Roach, L. Zhai, A. V. Skurat, 2004, Archives of biochemistry and biophysics.

GNIP, a Novel Protein That Binds and Activates Glycogenin, the Self-glucosylating Initiator of Glycogen Biosynthesis*

P. Roach, Alexander V. Skurat, Amy D. Dietrich, 2002, The Journal of Biological Chemistry.

Reliable scale-up of membrane protein over-expression by bacterial auto-induction: From microwell plates to pilot scale fermentations

S. Baldwin, M. McPherson, S. Phillips, 2008, Molecular membrane biology.

Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen*

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2011, The Journal of Biological Chemistry.

A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression.

P. Roach, Q. Wang, O. Andrisani, 1994, The Journal of biological chemistry.

New Insights Into the Role and Mechanism of Glycogen Synthase Activation by Insulin

P. Roach, J. Lawrence, 1997, Diabetes.

Glucose Metabolism in Mice Lacking Muscle Glycogen

A. Depaoli-Roach, P. Roach, Jill M. Schroeder, 2005 .

Rabbit skeletal muscle glycogen synthase. II. Enzyme phosphorylation state and effector concentrations as interacting control parameters.

P. Roach, J. Larner,, 1976, The Journal of biological chemistry.

P. Roach, Wei Wang, 2004, Biochemical and biophysical research communications.

Rescue and activation of a binding-deficient insulin receptor. Evidence for intermolecular transphosphorylation.

P. Roach, S. Taylor, M. Taouis, 1994, The Journal of biological chemistry.

Biochemical characterization of Neurospora crassa glycogenin (GNN), the self‐glucosylating initiator of glycogen synthesis

P. Roach, H. Terenzi, W. Wilson, 2005, FEBS letters.

Abnormal Cardiac Development in the Absence of Heart Glycogen

A. Depaoli-Roach, P. Roach, W. Shou, 2004, Molecular and Cellular Biology.

Analysis of respiratory mutants reveals new aspects of the control of glycogen accumulation by the cyclin‐dependent protein kinase Pho85p

P. Roach, W. Wilson, Zhong Wang, 2002, FEBS letters.

Interactions between cAMP-dependent and SNF1 protein kinases in the control of glycogen accumulation in Saccharomyces cerevisiae.

P. Roach, Dongqing Huang, T. A. Hardy, 1994, The Journal of biological chemistry.

Ordered multisite protein phosphorylation. Analysis of glycogen synthase kinase 3 action using model peptide substrates.

P. Roach, C. Fiol, R. Roeske, 1990, The Journal of biological chemistry.

Novel Aspects of the Regulation of Glycogen Storage

P. Roach, W. Wilson, J. Mu, 1998, Journal of basic and clinical physiology and pharmacology.

6 – Principles of the Regulation of Enzyme Activity

P. Roach, 1980 .

Requirements for Catalysis in Mammalian Glycogenin*

P. Roach, T. Hurley, Jing Zhou, 2005, Journal of Biological Chemistry.

Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease*

M. Ishihara, P. Azadi, Christopher J. Contreras, 2014, The Journal of Biological Chemistry.

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.

C. V. Vander Kooi, Matthew S. Gentry, Jéssica K A Macêdo, 2021, Cell metabolism.

Identification of phosphorylation sites in peptides using a microsequencer.

P. Roach, Y. Wang, 1991, Methods in enzymology.

Phosphoserine as a recognition determinant for glycogen synthase kinase-3: phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1.

A. Depaoli-Roach, P. Roach, Y. H. Wang, 1988, Archives of biochemistry and biophysics.

Restoration of muscle functionality by genetic suppression of glycogen synthesis in a murine model of Pompe disease.

E. Richard, P. Roach, N. Raben, 2010, Human molecular genetics.

Ca2+-stimulated phosphorylation of muscle glycogen synthase by phosphorylase b kinase.

A. Depaoli-Roach, P. Roach, J. Larner,, 1978, Journal of cyclic nucleotide research.

Recombinant rabbit muscle casein kinase I α is inhibited by heparin and activated by polylysine

K. Longenecker, P. Graves, A. Depaoli-Roach, 1992 .

Crystallographic studies of casein kinase I delta toward a structural understanding of auto-inhibition.

K. Longenecker, P. Roach, T. Hurley, 1998, Acta crystallographica. Section D, Biological crystallography.

Modification of glycogen synthase activity in isolated rat hepatocytes by tumor-promoting phorbol esters: evidence for differential regulation of glycogen synthase and phosphorylase.

P. Roach, M. Goldman, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of glycogen synthase. Identification of residues involved in regulation by the allosteric ligand glucose-6-P and by phosphorylation.

P. Roach, W. Wilson, B. A. Pederson, 2000, The Journal of biological chemistry.

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage

P. Roach, G. Dellgren, G. Tasca, 2019, The Journal of clinical endocrinology and metabolism.

cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide.

J. Dixon, P. Roach, J. Corbin, 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.

C. Wells, A. Depaoli-Roach, P. Roach, 2011, The Journal of Biological Chemistry.

Equipping a Research Scale Fermentation Laboratory for Production of Membrane Proteins

S. Baldwin, P. Stockley, P. Roach, 2008 .

Phosphoserine in peptide substrates can specify casein kinase II action.

P. Roach, T. W. Hrubey, 1990, Biochemical and biophysical research communications.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Increased glycogen accumulation in transgenic mice overexpressing glycogen synthase in skeletal muscle.

P. Roach, J. Lawrence, J. Manchester, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Are there errors in glycogen biosynthesis and is laforin a repair enzyme?

P. Roach, Peter J. Roach, 2011, FEBS letters.

Metabolite concentrations and concentration ratios in metabolic regulation.

D. E. Atkinson, P. Roach, J. S. Schwedes, 1975, Advances in enzyme regulation.

Incorporation of phosphate into glycogen by glycogen synthase.

Christopher J. Contreras, A. Depaoli-Roach, P. Roach, 2016, Archives of biochemistry and biophysics.

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity.

C. Worby, Matthew S. Gentry, A. Depaoli-Roach, 2012, Human molecular genetics.

Relationship between glycogen accumulation and the laforin dual specificity phosphatase.

A. Depaoli-Roach, P. Roach, N. Raben, 2006, Biochemical and biophysical research communications.

Catalytic site of rabbit glycogen synthase isozymes. Identification of an active site lysine close to the amino terminus of the subunit.

P. Roach, Y. Wang, A. Mahrenholz, 1988, The Journal of biological chemistry.

hepatocytesrelease and decrease glucokinase in Sucrose diets increase glucose-6-phosphatase and

P. Roach, G. Kraft, D. Neal, 2015 .

Increased glycogen storage in yeast results in less branched glycogen.

P. Roach, W. Wilson, Wendy J Tomamichel, 2004, Biochemical and biophysical research communications.

Direct detection of glycogenin reaction products during glycogen initiation.

Mu Wang, P. Roach, T. Hurley, 2006, Biochemical and biophysical research communications.

Phosphorylation of nerve growth factor receptor proteins in sympathetic neurons and PC12 cells. In vitro phosphorylation by the cAMP-independent protein kinase FA/GSK-3.

P. Roach, J. Lawrence, E. Johnson, 1986, The Journal of biological chemistry.

Structural basis by which a recessive mutation in the alpha-subunit of the insulin receptor affects insulin binding.

P. Roach, S. Taylor, M. Taouis, 1994, The Journal of biological chemistry.

Calcium and calmodulin activation of muscle phosphorylase kinase

A. Depaoli-Roach, P. Roach, J. Gibbs, 1979, FEBS Letters.

Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae

P. Roach, X. Wu, K. Tatchell, 2001, Molecular Genetics and Genomics.

Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme.

A. Depaoli-Roach, P. Roach, M. Camici, 1984, The Journal of biological chemistry.

Iron-sulfur center of biotin synthase and lipoate synthase.

M. Fontecave, P. Roach, P. Roach, 2000, Biochemistry.

The subcellular localization of yeast glycogen synthase is dependent upon glycogen content.

P. Roach, M. Burke, W. Wilson, 2010, Canadian journal of microbiology.

Phosphoprotein phosphatase inhibitor-2. Identification as a species of molecular weight 31,000 in rabbit muscle, liver, and other tissues.

A. Depaoli-Roach, P. Roach, 1985, The Journal of biological chemistry.

Initiation of glycogen synthesis. Control of glycogenin by glycogen phosphorylase.

A. Depaoli-Roach, P. Roach, A. V. Skurat, 1993, The Journal of biological chemistry.

Rabbit Liver Glycogen Synthase

P. Roach, Marcella Camicif, Anna A. DePaoli-Roachg, 1982 .

Saccharomyces gene deletion project: applications and use in the study of protein kinases and phosphatases.

P. Roach, W. Wilson, 2003, Methods in enzymology.

Phosphorylation of glycogen synthase by the Ca2+- and phospholipid-activated protein kinase (protein kinase C).

A. Depaoli-Roach, P. Roach, Z. Ahmad, 1984, The Journal of biological chemistry.

Mutations of muscle glycogen synthase that disable activation by glucose 6-phosphate.

I. Hanashiro, P. Roach, 2002, Archives of biochemistry and biophysics.

A high-throughput assay of membrane protein stability

S. Baldwin, M. McPherson, S. Phillips, 2008, Molecular membrane biology.

Comparison of insulin lispro mixture 25/75 with insulin glargine during a 24‐h standardized test‐meal period in patients with Type 2 diabetes

P. Roach, P. Roach, J. Malone, 2006, Diabetic medicine : a journal of the British Diabetic Association.

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

A. Depaoli-Roach, P. Roach, N. Morral, 2017, The Journal of Biological Chemistry.

Humalog® Mix50™ before carbohydrate‐rich meals in type 2 diabetes mellitus

P. Roach, B. Campaigne, P. Roach, 2003, Diabetes, obesity & metabolism.

The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.

N. Fastman, A. Depaoli-Roach, P. Roach, 2022, Cell reports.

Phosphate incorporation during glycogen synthesis and Lafora disease.

M. Ishihara, P. Azadi, Christopher J. Contreras, 2011, Cell metabolism.

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin*

P. Roach, V. Tagliabracci, Catalina M. Meyer, 2010, The Journal of Biological Chemistry.

Lafora disease offers a unique window into neuronal glycogen metabolism

J. Serratosa, Matthew S. Gentry, P. Roach, 2018, The Journal of Biological Chemistry.