N. Khazanov

发表

Sliding of p53 along DNA can be modulated by its oligomeric state and by cross-talks between its constituent domains.

Yaakov Levy, Netaly Khazanov, N. Khazanov, 2011, Journal of molecular biology.

Thermodynamic correction of F 508 del-CFTR 1 Ligand binding to a remote site thermodynamically corrects the F 508 del mutation in the human cystic fibrosis transmembrane conductance regulator

J. Riordan, B. Stockwell, N. Dokholyan, 2018 .

Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.

J. Riordan, H. Ding, J. Kappes, 2018, Biochimica et biophysica acta. Biomembranes.

From Catalytic Mechanism to Rational Design of Reversible Covalent Inhibitors of Serine and Cysteine Hydrolases

N. Khazanov, M. Shokhen, A. Albeck, 2014 .

The mechanism of papain inhibition by peptidyl aldehydes

N. Khazanov, M. Shokhen, A. Albeck, 2011, Proteins.

Challenging a paradigm: Theoretical calculations of the protonation state of the Cys25‐His159 catalytic diad in free papain

N. Khazanov, M. Shokhen, A. Albeck, 2009, Proteins.

Novel inhibitors of leukocyte transendothelial migration.

H. Senderowitz, N. Khazanov, B. Imhof, 2019, Bioorganic chemistry.

Phloretin, an Apple Phytoalexin, Affects the Virulence and Fitness of Pectobacterium brasiliense by Interfering With Quorum-Sensing

H. Senderowitz, N. Khazanov, M. Weitman, 2021, Frontiers in Plant Science.

Interkingdom Signaling Interference: The Effect of Plant-Derived Small Molecules on Quorum Sensing in Plant-Pathogenic Bacteria.

H. Senderowitz, N. Khazanov, A. Charkowski, 2021, Annual review of phytopathology.

Direct binding of salicylic acid to Pectobacterium N-acyl-homoserine lactone synthase.

H. Senderowitz, N. Khazanov, S. Burdman, 2020, ACS chemical biology.

Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site

H. Senderowitz, N. Khazanov, H. Eldar-Finkelman, 2020, International journal of molecular sciences.

A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease.

Hanoch Senderowitz, Or Kakhlon, Leonardo J Solmesky, 2017, The Biochemical journal.

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator

J. Riordan, B. Stockwell, N. Dokholyan, 2018, The Journal of Biological Chemistry.

Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.

H. Senderowitz, N. Khazanov, J. Sévigny, 2019, European journal of medicinal chemistry.

Enzyme Isoselective Inhibitors: A Tool for Binding‐Trend Analysis

N. Khazanov, M. Shokhen, A. Albeck, 2006, ChemMedChem.

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

K. S. Rajan, H. Senderowitz, S. Michaeli, 2021, mBio.

The spliced leader RNA silencing (SLS) pathway in Trypanosoma brucei is induced by perturbations of endoplasmic reticulum, Golgi, or mitochondrial proteins factors and functional analysis of SLS inducing kinase, PK3

K. S. Rajan, H. Senderowitz, S. Michaeli, 2021, bioRxiv.

Asymmetric DNA-search dynamics by symmetric dimeric proteins.

N. Khazanov, Y. Levy, A. Marcovitz, 2013, Biochemistry.

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.

A. Gaggar, H. Senderowitz, J. Blalock, 2019, Developmental cell.

Potentiators exert distinct effects on human, murine, and Xenopus CFTR.

H. Senderowitz, N. Khazanov, Barry R. Imhoff, 2016, American journal of physiology. Lung cellular and molecular physiology.

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Hanoch Senderowitz, Zhengrong Yang, John F. Hunt, 2021, J. Chem. Inf. Model..

The Q359K/T360K mutation causes cystic fibrosis in Georgian Jews.

H. Mussaffi, D. Prais, M. Mei-Zahav, 2018, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Phenotypic and molecular characteristics of CF patients carrying the I1234V mutation.

H. Senderowitz, N. Khazanov, I. Sarouk, 2020, Respiratory medicine.

Enzyme Isoselective Inhibitors: Application to Drug Design

N. Khazanov, M. Shokhen, A. Albeck, 2006, ChemMedChem.

Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates

E. Fisher, H. Senderowitz, N. Khazanov, 2019, Protein science : a publication of the Protein Society.

Plant phenolic volatiles inhibit quorum sensing in pectobacteria and reduce their virulence by potential binding to ExpI and ExpR proteins

H. Senderowitz, N. Khazanov, S. Burdman, 2016, Scientific Reports.

Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases

N. Khazanov, M. Shokhen, A. Albeck, 2007, Proteins.

The Cooperative Effect Between Active Site Ionized Groups and Water Desolvation Controls the Alteration of Acid/Base Catalysis in Serine Proteases

N. Khazanov, M. Shokhen, A. Albeck, 2007, Chembiochem : a European journal of chemical biology.

Guaiacol as a drug candidate for treating adult polyglucosan body disease.

P. Escribá, H. Senderowitz, W. Yue, 2018, JCI insight.

Specific stabilization of CFTR by phosphatidylserine.

J. Kappes, H. Senderowitz, N. Khazanov, 2017, Biochimica et biophysica acta. Biomembranes.

Design of Compact Biomimetic Cellulose Binding Peptides as Carriers for Cellulose Catalytic Degradation.

H. Senderowitz, N. Khazanov, G. Goobes, 2016, The journal of physical chemistry. B.

Inhibition of AcrAB-TolC enhances antimicrobial activity of phytochemicals in Pectobacterium brasiliense

H. Senderowitz, N. Khazanov, Z. Kerem, 2023, Frontiers in Plant Science.

A comparison between 2D and 3D descriptors in QSAR modeling based on bio‐active conformations

Jacob O. Spiegel, H. Senderowitz, N. Khazanov, 2023, Molecular informatics.

Asymmetric DNA-search dynamics by symmetric dimeric proteins.

N. Khazanov, Y. Levy, Amir Marcovitz, 2013, Biochemistry.

The mechanism of papain inhibition by peptidyl aldehydes

N. Khazanov, M. Shokhen, A. Albeck, 2011, Proteins.

Guaiacol as a drug candidate for treating adult polyglucosan body disease.

P. Escribá, H. Senderowitz, N. Khazanov, 2018, JCI insight.