H. Tidow

发表

Quaternary structures of tumor suppressor p53 and a specific p53–DNA complex

A. Fersht, M. Valle, D. Svergun, 2007, Proceedings of the National Academy of Sciences.

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

A. Fersht, M. Blackledge, P. Markwick, 2008, Proceedings of the National Academy of Sciences.

Effects of Oncogenic Mutations and DNA Response Elements on the Binding of p53 to p53-binding Protein 2 (53BP2)*

Henning Tidow, A. Fersht, D. Veprintsev, 2006, Journal of Biological Chemistry.

Core domain interactions in full-length p53 in solution

Antonina Andreeva, Alan R. Fersht, Dmitry B. Veprintsev, 2006, Proceedings of the National Academy of Sciences of the United States of America.

The novel p53 isoform “delta p53” is a misfolded protein and does not bind the p21 promoter site

A. Fersht, D. Veprintsev, H. Tidow, 2008, Protein science : a publication of the Protein Society.

Solution structure of p53 core domain: Structural basis for its instability

Alan R. Fersht, Henning Tidow, A. Fersht, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity.

Abdul Waheed, Jessica Schmiesing, Stephan Storch, 2018, Cell reports.

Nocardamine-dependent iron uptake in Pseudomonas aeruginosa: exclusive involvement of the FoxA outer membrane transporter.

H. Tidow, L. Kuhn, P. Hammann, 2020, ACS chemical biology.

High-throughput stability screening for detergent-solubilized membrane proteins

T. Marlovits, H. Tidow, M. Garcia-Alai, 2019, Scientific Reports.

Structural diversity of calmodulin binding to its target sites

Poul Nissen, Henning Tidow, P. Nissen, 2013, The FEBS journal.

Crystal structure of a domain‐swapped photoactivatable sfGFP variant provides evidence for GFP folding pathway

H. Tidow, C. Uetrecht, N. Huse, 2019, The FEBS journal.

Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.

A. Fersht, H. Tidow, T. Rutherford, 2009, Structure.

Inhibition of SARS-CoV-2 main protease by allosteric drug-binding

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020, bioRxiv.

Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020 .

Expression, purification, crystallization and preliminary X-ray analysis of calmodulin in complex with the regulatory domain of the plasma-membrane Ca2+-ATPase ACA8.

P. Nissen, H. Tidow, M. Palmgren, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+‐binding domain essential for structural integrity and channel activity

H. Tidow, R. Fliegert, Simon Sander, 2022, Protein science : a publication of the Protein Society.

Cryo‐EM structure of MsbA in saposin‐lipid nanoparticles (Salipro) provides insights into nucleotide coordination

H. Tidow, D. Traore, S. Prévost, 2021, The FEBS journal.

Crystal Structure of a Group I Energy Coupling Factor Vitamin Transporter S Component in Complex with Its Cognate Substrate

H. Tidow, A. Andreeva, I. Josts, 2016, Cell chemical biology.

Na+,K+-ATPase as a docking station: protein–protein complexes of the Na+,K+-ATPase

P. Nissen, H. Tidow, L. Reinhard, 2012, Cellular and Molecular Life Sciences.

A bimodular mechanism of calcium control in eukaryotes

C. Wiuf, P. Nissen, H. Tidow, 2012, Nature.

Disease‐causing mutations affecting surface residues of mitochondrial glutaryl‐CoA dehydrogenase impair stability, heteromeric complex formation and mitochondria architecture

H. Tidow, M. Schweizer, S. Gersting, 2017, Human molecular genetics.

A novel CHHC Zn-finger domain found in spliceosomal proteins and tRNA modifying enzymes

Antonina Andreeva, Henning Tidow, H. Tidow, 2008, Bioinform..

Characterisation of Plasmodium falciparum populations selected on the human endothelial receptors P-selectin, E-selectin, CD9 and CD151

T. Roeder, H. Tidow, T. Gutsmann, 2017, Scientific Reports.

Crystal structure determination and functional characterization of the metallochaperone SlyD from Thermus thermophilus.

H. Tidow, C. Löw, P. Neumann, 2010, Journal of molecular biology.

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9

H. Tidow, T. Rutherford, R. Fliegert, 2021, The FEBS journal.

A single extracellular loop of FoxA controls ligand specificity, uptake, and signaling in Pseudomonas aeruginosa

H. Tidow, L. Burrows, Gerard D. Wright, 2022, bioRxiv.

Computational models in the service of X‐ray and cryo‐electron microscopy structure determination

J. Moult, Andriy Kryshtafovych, A. Lupas, 2021, Proteins.

How are ion pumps and agrin signaling integrated?

P. Nissen, H. Tidow, A. Aperia, 2010, Trends in biochemical sciences.

Structure and stability of the Human respiratory syncytial virus M2–1 RNA-binding core domain reveals a compact and cooperative folding unit

H. Tidow, G. de Prat-Gay, S. Esperante, 2017, Acta crystallographica. Section F, Structural biology communications.

Ternary structure of the outer membrane transporter FoxA with resolved signalling domain provides insights into TonB-mediated siderophore uptake

H. Tidow, I. Josts, K. Veith, 2019, eLife.

Structural insights into a novel family of integral membrane siderophore reductases

H. Tidow, I. Schalk, Vincent Normant, 2021, Proceedings of the National Academy of Sciences.

New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain

H. Tidow, A. Nicke, M. G. Alai, 2022, The Journal of biological chemistry.

FoldAffinity: binding affinities from nDSF experiments

M. Wilmanns, H. Tidow, M. Garcia-Alai, 2021, Scientific Reports.

Comparison of lipidic carrier systems for integral membrane proteins – MsbA as case study

H. Tidow, S. Busch, I. Josts, 2019, Biological chemistry.

The solution structure of a chimeric LEKTI domain reveals a chameleon sequence.

H. Tidow, U. Marx, C. Sommerhoff, 2004, Biochemistry.

General structural motifs of amyloid protofilaments

Gerd Krause, Neil Ferguson, Hartmut Oschkinat, 2006, Proceedings of the National Academy of Sciences.

Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020, bioRxiv.

Conformation-specific detection of calmodulin binding using the unnatural amino acid p-azido-phenylalanine (AzF) as an IR-sensor

H. Tidow, N. Huse, I. Josts, 2018, Structural dynamics.

X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2021, Science.

High-throughput stability screening for detergent-solubilized membrane proteins

T. Marlovits, H. Tidow, M. Garcia-Alai, 2019, Scientific Reports.

Structural Kinetics of MsbA Investigated by Stopped-Flow Time-Resolved Small-Angle X-Ray Scattering.

Diana C. F. Monteiro, D. Svergun, H. Tidow, 2019, Structure.

Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.

A. Fersht, H. Tidow, T. Rutherford, 2007, Journal of molecular biology.

Na+,K+-ATPase as a docking station: protein–protein complexes of the Na+,K+-ATPase

P. Nissen, H. Tidow, L. Reinhard, 2012, Cellular and Molecular Life Sciences.

Combined in vitro and in silico analyses of missense mutations in GNPTAB provide new insights into the molecular bases of mucolipidosis II and III alpha/beta

B. Tüysüz, H. Tidow, S. Pohl, 2020, Human mutation.

Identification of the interaction domains between α‐ and γ‐subunits of GlcNAc‐1‐phosphotransferase

H. Tidow, T. Braulke, S. Pohl, 2016, FEBS letters.

Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2

H. Tidow, T. Rutherford, M. G. Garcia Alai, 2019, Biochimica et biophysica acta. Molecular cell research.

Conformational States of ABC Transporter MsbA in a Lipid Environment Investigated by Small-Angle Scattering Using Stealth Carrier Nanodiscs.

D. Svergun, H. Tidow, H. Mertens, 2018, Structure.

Characterisation of Plasmodium falciparum populations selected on the human endothelial receptors P-selectin, E-selectin, CD9 and CD151

T. Roeder, T. Burmester, H. Tidow, 2017, Scientific Reports.

Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin

D. Svergun, H. Tidow, C. Uetrecht, 2018, Communications Biology.

Computational models in the service of X-ray and cryo-EM structure determination

Andrei N. Lupas, Andriy Kryshtafovych, John Moult, 2021 .

cADPR Does Not Activate TRPM2

H. Tidow, A. Guse, R. Fliegert, 2022, International journal of molecular sciences.

Structural and biophysical characterisation of agrin laminin G3 domain constructs.

P. Nissen, H. Tidow, D. Mattle, 2011, Protein engineering, design & selection : PEDS.

Lipid‐like Peptides can Stabilize Integral Membrane Proteins for Biophysical and Structural Studies

H. Tidow, I. Josts, K. Veith, 2017, Chembiochem : a European journal of chemical biology.

Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin

D. Svergun, H. Tidow, C. Uetrecht, 2018, Communications Biology.

How are ion pumps and agrin signaling integrated?

P. Nissen, H. Tidow, A. Aperia, 2010, Trends in biochemical sciences.

Crystal structures of the outer membrane transporter FoxA provide novel insights into TonB-mediated siderophore uptake and signalling

H. Tidow, I. Josts, K. Veith, 2019, bioRxiv.

Structural diversity of calmodulin binding to its target sites

P. Nissen, H. Tidow, 2013, The FEBS journal.

Population Dynamics of Stretching Excitations of p-Azido-phenylalanine Incorporated in Calmodulin-Peptide Complexes.

H. Tidow, N. Huse, A. Creon, 2022, The journal of physical chemistry. B.

Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction

H. Tidow, L. Burrows, Gerard D. Wright, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Human Mutation

B. Tüysüz, H. Tidow, S. Pohl, 2019 .