O. Laptenko

发表

The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein.

J. Manfredi, C. Prives, O. Laptenko, 2016, Trends in biochemical sciences.

Transcriptional regulation by p53: one protein, many possibilities

C. Prives, O. Laptenko, C Prives, 2006, Cell Death and Differentiation.

Accurate and sensitive quantification of protein-DNA binding affinity

R. Mann, H. Bussemaker, William Freed-Pastor, 2018, Proceedings of the National Academy of Sciences.

Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 Å resolution

S. Yokoyama, D. Vassylyev, O. Laptenko, 2002, Nature.

DECOD: fast and accurate discriminative DNA motif finding

Ziv Bar-Joseph, Marcel H. Schulz, Shan Zhong, 2011, Bioinform..

p53: master of life, death, and the epigenome

C. Prives, O. Laptenko, 2017, Genes & Development.

Escherichia coli transcript cleavage factors GreA and GreB: functions and mechanisms of action.

O. Laptenko, S. Borukhov, J. Lee, 2001, Methods in enzymology.

The p53-HAT connection

C. Prives, O. Laptenko, 2012, Cell cycle.

The C terminus of p53 binds the N-terminal domain of MDM2

C. Prives, O. Laptenko, A. Friedler, 2011, Nature Structural &Molecular Biology.

Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation

A. D. Clark, R. Ebright, S. Tuske, 2005, Cell.

pH‐dependent conformational switch activates the inhibitor of transcription elongation

O. Laptenko, X. Kong, Jookyung J Lee, 2006, The EMBO journal.

Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase

O. Laptenko, I. Lomakin, Jookyung J Lee, 2003, The EMBO journal.

Purification, crystallization and initial crystallographic analysis of RNA polymerase holoenzyme from Thermus thermophilus.

S. Yokoyama, T. Shibata, D. Vassylyev, 2002, Acta crystallographica. Section D, Biological crystallography.

Bacterial transcription elongation factors: new insights into molecular mechanism of action

Oleg Laptenko, Jookyung Lee, O. Laptenko, 2004, Molecular microbiology.

Biochemical assays of Gre factors of Thermus thermophilus.

O. Laptenko, S. Borukhov, 2003, Methods in enzymology.

Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells

A. Børresen-Dale, B. Tian, J. Bargonetti, 2015, Genes & development.

Mutant p 53 cooperates with the SWI / SNF chromatin remodeling complex to regulate VEGFR 2 in breast cancer cells

A. Børresen-Dale, B. Tian, J. Bargonetti, 2015 .

p53-dependent Induction of PVT1 and miR-1204*

N. Caplen, A. Barsotti, C. Prives, 2011, The Journal of Biological Chemistry.

Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes.

R. Mann, H. Bussemaker, C. Prives, 2017, Cell reports.

MOZ increases p53 acetylation and premature senescence through its complex formation with PML

C. Prives, O. Laptenko, Y. Taya, 2013, Proceedings of the National Academy of Sciences.

p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities

J. Manfredi, C. Prives, O. Laptenko, 2021, Molecular Cancer Research.

p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation

C. Prives, O. Laptenko, E. Freulich, 2011, Proceedings of the National Academy of Sciences.

Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers

C. Prives, O. Laptenko, David R. Tong, 2018, Genes & development.

The C-terminus of p53 binds the N-terminal domain of MDM2

C. Prives, O. Laptenko, A. Friedler, 2010, Nature Structural &Molecular Biology.

The C terminus of p 53 binds the N-terminal domain of MDM 2

C. Prives, O. Laptenko, A. Friedler, 2010 .

Lysines in the tetramerization domain of p53 selectively modulate G1 arrest

C. Prives, O. Karni-Schmidt, O. Laptenko, 2016, Cell cycle.

The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

I. Simon, J. Manfredi, C. Prives, 2015, Molecular cell.

The p 53 C Terminus Contr ols Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain Graphical Abstract Highlights

I. Simon, J. Manfredi, C. Prives, 2015 .

Control of the respiratory metabolism of Thermus thermophilus by the nitrate respiration conjugative element NCE

F. Cava, O. Laptenko, P. Gómez-Puertas, 2007, Molecular microbiology.

Purification, crystallization and initial crystallographic analysis of RNA polymerase holoenzyme from Thermus thermophilus.

S. Yokoyama, T. Shibata, D. Vassylyev, 2002 .

p53-dependent Induction of PVT1 and miR-1204*

N. Caplen, A. Barsotti, C. Prives, 2011, The Journal of Biological Chemistry.

Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 Å resolution

S. Yokoyama, D. Vassylyev, O. Laptenko, 2002 .