K. Fernandes

发表

p53 isoforms can regulate p53 transcriptional activity.

David P Lane, D. Lane, M. Saville, 2005, Genes & development.

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

M. Saville, K. Fernandes, C. Proby, 2018, Oncotarget.

p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage

D. Lane, J. Bourdon, K. Fernandes, 2011, Cell Death and Differentiation.

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity

M. Saville, K. Fernandes, C. Proby, 2018, Oncotarget.

Δ160p53 is a novel N‐terminal p53 isoform encoded by Δ133p53 transcript

Virginie Marcel, J. Bourdon, K. Fernandes, 2010, FEBS letters.

Detecting p53 isoforms at protein level.

D. Lane, J. Bourdon, K. Fernandes, 2013, Methods in molecular biology.

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity

D. Lane, J. Bourdon, K. Fernandes, 2011, Cell Death and Differentiation.

Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene.

E. Appella, A. Fornace, D. Lane, 2006, Cancer research.

The p53 isoforms are differentially modified by Mdm2

D. Lane, J. Bourdon, K. Fernandes, 2012, Cell cycle.

Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane

D. Lane, J. Bourdon, K. Fernandes, 2002, The Journal of cell biology.

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients

A. Thompson, D. Lane, C. Purdie, 2011, Breast Cancer Research.

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

M. Saville, K. Fernandes, C. Proby, 2019, The Journal of investigative dermatology.

TP53 drives invasion through expression of its Δ133p53β variant

J. Reményi, F. Fuller-Pace, A. Thompson, 2016, eLife.

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

D. Lane, J. Bourdon, K. Fernandes, 2014, Cell Death and Differentiation.

Detecting and quantifying p53 isoforms at mRNA level in cell lines and tissues.

D. Lane, J. Bourdon, K. Fernandes, 2013, Methods in molecular biology.

TP53 drives invasion through expression of its 133p53 variant

J. Reményi, F. Fuller-Pace, J. Bourdon, 2016 .

p 53 mutant breast cancer patients expressing p 53 γ have as good a prognosis as wild-type p 53 breast cancer patients

A. Thompson, D. Lane, C. Purdie, 2017 .

Diverse p63 and p73 isoforms regulate D133p53 expression through modulation of the internal TP53 pomoter activity

J. Bourdon, K. Fernandes, F. Murray-Zmijewski, 2020 .

Detecting p53 isoforms at protein level.

D. Lane, J. Bourdon, K. Fernandes, 2013, Methods in molecular biology.