S. Uddin

发表

Decomposing Dynamical Couplings in Mutated scFv Antibody Fragments into Stabilizing and Destabilizing Effects.

D. Jacobs, Azhagiya Singam Ettayapuram Ramaprasad, S. Uddin, 2017, Journal of the American Chemical Society.

Mutations in Antibody Fragments Modulate Allosteric Response Via Hydrogen-Bond Network Fluctuations.

D. Jacobs, D. Livesay, Amit Srivastava, 2016, Biophysical journal.

Factors influencing antibody stability at solid–liquid interfaces in a high shear environment

Shahid Uddin, Daniel G Bracewell, S. Uddin, 2009, Biotechnology progress.

A novel combined strategy for the physical PEGylation of polypeptides.

P. Caliceti, C. F. van der Walle, S. Uddin, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

S. Uddin, J. Derrick, A. Pluen, 2019, Pharmaceutical Research.

Dipicolinic acid as a novel spore-inspired excipient for antibody formulation.

C. F. van der Walle, S. Uddin, Peng Ke, 2017, International journal of pharmaceutics.

The Effect of Lipidation on the Self-Assembly of the Gut-Derived Peptide Hormone PYY3-36.

S. Uddin, I. Hamley, J. Hutchinson, 2018, Bioconjugate chemistry.

Modulation of the hydration water around monoclonal antibodies on addition of excipients detected by terahertz-time domain spectroscopy

V. Wallace, C. F. van der Walle, J. Zeitler, 2015, 2015 40th International Conference on Infrared, Millimeter, and Terahertz waves (IRMMW-THz).

A pH-Induced Switch in Human Glucagon-like Peptide-1 Aggregation Kinetics.

S. Uddin, S. Bishop, S. Jackson, 2016, Journal of the American Chemical Society.

Emerging technologies for combating pandemics

S. Uddin, D. Lamprou, E. Weaver, 2022, Expert review of medical devices.

Determination of protein-protein interactions at high co-solvent concentrations using static and dynamic light scattering.

S. Uddin, Peng Ke, S. Ekizoglou, 2020, Journal of pharmaceutical sciences.

The effect of palmitoylation on the conformation and physical stability of a model peptide hormone.

C. F. van der Walle, S. Uddin, J. Casas-Finet, 2014, International journal of pharmaceutics.

Characterisation of Stress-Induced Aggregate Size Distributions and Morphological Changes of a Bi-Specific Antibody Using Orthogonal Techniques.

C. F. van der Walle, S. Uddin, J. Casas-Finet, 2015, Journal of pharmaceutical sciences.

The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl

C. F. van der Walle, S. Uddin, A. Golovanov, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Adsorption behavior of a human monoclonal antibody at hydrophilic and hydrophobic surfaces

C. F. van der Walle, S. Uddin, M. Skoda, 2013, mAbs.

Antibody adsorption on the surface of water studied by neutron reflection

J. Lu, R. Narwal, C. F. van der Walle, 2017, mAbs.

Specific ion and buffer effects on protein-protein interactions of a monoclonal antibody.

Malgorzata B. Tracka, J. Warwicker, C. F. van der Walle, 2015, Molecular pharmaceutics.

The role of electrostatics in protein-protein interactions of a monoclonal antibody.

Malgorzata B. Tracka, J. Warwicker, C. F. van der Walle, 2014, Molecular pharmaceutics.

Rigidity Emerges during Antibody Evolution in Three Distinct Antibody Systems: Evidence from QSFR Analysis of Fab Fragments

Tong Li, Malgorzata B. Tracka, Shahid Uddin, 2015, PLoS Comput. Biol..

The effect of protein concentration on the viscosity of a recombinant albumin solution formulation

Shahid Uddin, Cameron Alexander, Clive J. Roberts, 2016 .

Understanding how charge and hydrophobicity influence globular protein adsorption to alkanethiol and material surfaces.

M. Welland, S. Uddin, S. Bishop, 2019, Journal of materials chemistry. B.

Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly

David Baker, M. Welland, P. Vicini, 2017, Nature Communications.

Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range.

Shahid Uddin, Alain Pluen, Maryam Shah, 2017, International journal of pharmaceutics.

Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.

Shahid Uddin, C. F. van der Walle, S. Uddin, 2017, Molecular pharmaceutics.

Characterizing monoclonal antibody formulations in arginine glutamate solutions using 1H NMR spectroscopy

Shahid Uddin, Alexander P. Golovanov, C. F. van der Walle, 2016, mAbs.

The effect of arginine glutamate on the stability of monoclonal antibodies in solution

Malgorzata B. Tracka, Shahid Uddin, Alexander P. Golovanov, 2014, International journal of pharmaceutics.

The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment

Shahid Uddin, Alain Pluen, Jim Warwicker, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Chapter 25: Peptide Drug/Device Combinations

S. Uddin, 2020, Development of Biopharmaceutical Drug-Device Products.

Determining Antibody Stability: Creation of Solid‐Liquid Interfacial Effects within a High Shear Environment

Shahid Uddin, Daniel G Bracewell, S. Uddin, 2007, Biotechnology progress.

Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.

J. Warwicker, C. F. van der Walle, G. Winter, 2023, Molecular pharmaceutics.

Biotherapeutic protein formulation variables influence protein integrity and can promote post-translational modifications as shown using chicken egg white lysozyme as a model system

S. Uddin, C. Smales, Jane F. Povey, 2015, Biotechnology Letters.

Application of ER Stress Biomarkers to Predict Formulated Monoclonal Antibody Stability.

S. Uddin, C. Smales, Emma J. Mead, 2019, Biotechnology journal.

Cluster Percolation Causes Shear Thinning Behavior in Concentrated Solutions of Monoclonal Antibodies.

C. F. van der Walle, S. Uddin, A. Pluen, 2021, Molecular pharmaceutics.

Coarse-Grained Modeling of Antibodies from Small-Angle Scattering Profiles.

C. F. van der Walle, S. Uddin, C. Avendaño, 2017, The journal of physical chemistry. B.

Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly

David Baker, M. Welland, P. Vicini, 2017, Nature Communications.

Comparison the Effectiveness of Manual Therapy, Electrotherapy and Core Stability Exercise vs Electrotherapy, Traction and Traditional Exercise for Acute Low Back Pain

S. Uddin, I. Jahan, Z. Uddin, 2015 .

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

S. Uddin, J. Derrick, A. Pluen, 2019, Pharmaceutical Research.

Redistribution of Flexibility in Stabilizing Antibody Fragment Mutants Follows Le Châtelier’s Principle

Malgorzata B. Tracka, Shahid Uddin, Donald J. Jacobs, 2014, PloS one.

Micro- and macro-viscosity relations in high concentration antibody solutions.

C. F. van der Walle, S. Uddin, A. Pluen, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Neutron Reflection Study of Surface Adsorption of Fc, Fab, and the Whole mAb.

J. Lu, J. Warwicker, R. Narwal, 2017, ACS applied materials & interfaces.

The Present and Future Role of Microfluidics for Protein and Peptide-Based Therapeutics and Diagnostics

Shahid Uddin, Dimitrios A. Lamprou, Edward Weaver, 2021, Applied Sciences.

Determination of protein-protein interactions in a mixture of two monoclonal antibodies.

J. Warwicker, C. F. van der Walle, S. Uddin, 2019, Molecular pharmaceutics.

Interaction and destabilization of a monoclonal antibody and albumin to surfaces of varying functionality and hydrophobicity.

C. F. van der Walle, S. Uddin, D. Lamprou, 2012, International journal of pharmaceutics.

Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization.

C. F. van der Walle, G. Winter, S. Uddin, 2019, Molecular pharmaceutics.

Characterisation of Stress-Induced Aggregate Size Distributions and Morphological Changes of a Bi-Specific Antibody Using Orthogonal Techniques.

Malgorzata B. Tracka, C. F. van der Walle, S. Uddin, 2015, Journal of pharmaceutical sciences.