B. Nocek

发表

Functional properties and structural characterization of rice δ1-pyrroline-5-carboxylate reductase

D. Funck, G. Forlani, M. Bertazzini, 2015, Front. Plant Sci..

Conservation of the structure and function of bacterial tryptophan synthases

A. Joachimiak, M. Endres, B. Nocek, 2019, IUCrJ.

Biochemical and structural studies of two tetrameric nucleoside 2'-deoxyribosyltransferases from psychrophilic and mesophilic bacteria: Insights into cold-adaptation.

A. Joachimiak, B. Nocek, J. Fernández‐Lucas, 2021, International journal of biological macromolecules.

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

D. Paslier, A. Joachimiak, M. Ferrer, 2017, Scientific Reports.

Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases.

A. Joachimiak, B. Nocek, A. Savchenko, 2007, Journal of molecular biology.

The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways

S. Peisajovich, B. Nocek, P. Stogios, 2018, The Journal of Biological Chemistry.

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae

E. Koonin, Y. Wolf, K. Makarova, 2015, The Journal of Biological Chemistry.

1.6 Å Crystal structure of a PA2721 protein from pseudomonas aeruginosa—A potential drug‐resistance protein

A. Joachimiak, B. Nocek, A. Savchenko, 2006, Proteins.

The dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues

A. Joachimiak, B. Nocek, D. Gillner, 2008, JBIC Journal of Biological Inorganic Chemistry.

Biochemical and Structural Characterization of a Five-domain GH115 α-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T*

P. Gatenholm, E. Master, B. Nocek, 2016, The Journal of Biological Chemistry.

Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

A. Joachimiak, B. Nocek, R. Jedrzejczak, 2018, Biochemistry.

Gene selection and cloning approaches for co-expression and production of recombinant protein–protein complexes

A. Joachimiak, B. Nocek, R. Jedrzejczak, 2015, Journal of Structural and Functional Genomics.

Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity.

A. Joachimiak, B. Nocek, R. Jedrzejczak, 2011, Journal of molecular biology.

Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.

B. Nocek, P. Stogios, T. Skarina, 2015, Structure.

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

M. Lam, M. Taipale, B. Nocek, 2016, Molecular systems biology.

Assisted assignment of ligands corresponding to unknown electron density

T. A. Binkowski, A. Joachimiak, B. Nocek, 2010, Journal of Structural and Functional Genomics.

Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus.

A. Joachimiak, B. Nocek, T. Skarina, 2013, Journal of the American Chemical Society.

Structure of an amide bond forming Fγγ-glutamyl ligase from Archaeoglobus fulgidus-a member of a new family of non-ribosomal peptide synthases.

Robert H. White, B. Nocek, E. Evdokimova, 2007 .

Cleavable C-terminal His-tag vectors for structure determination

A. Joachimiak, B. Nocek, K. Tan, 2010, Journal of Structural and Functional Genomics.

Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE

B. Nocek, R. Holz, Rachel M Torrez, 2020, Antibiotics.

Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583

A. Joachimiak, F. Collart, B. Nocek, 2005 .

Crystallization and preliminary X-ray analysis of an acetone carboxylase from Xanthobacter autotrophicus strain Py2.

J. W. Peters, B. Nocek, J. Boyd, 2004, Acta crystallographica. Section D, Biological crystallography.

Atomic-Resolution 1.3 Å Crystal Structure, Inhibition by Sulfate, and Molecular Dynamics of the Bacterial Enzyme DapE.

B. Nocek, K. Olsen, R. Holz, 2021, Biochemistry.

An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.

A. Joachimiak, B. Nocek, M. Poręba, 2013, Biochimie.

Functional Characterization of Four Putative δ1-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis

A. Joachimiak, G. Forlani, B. Nocek, 2017, Front. Microbiol..

Crystallization and preliminary X-ray analysis of an R-2-hydroxypropyl-coenzyme M dehydrogenase.

J. W. Peters, B. Nocek, D. D. Clark, 2002, Acta crystallographica. Section D, Biological crystallography.

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

M. Ballicora, B. Nocek, K. Olsen, 2018, PloS one.

A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.

A. Joachimiak, B. Nocek, Łukasz Berlicki, 2016, European journal of medicinal chemistry.

Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases

B. Shen, G. Phillips, A. Joachimiak, 2015, Proceedings of the National Academy of Sciences.

Structure-Guided, Single-Point Modifications in the Phosphinic Dipeptide Structure Yield Highly Potent and Selective Inhibitors of Neutral Aminopeptidases

A. Joachimiak, B. Nocek, Łukasz Berlicki, 2014, Journal of medicinal chemistry.

Bisphosphonic acids and related compounds as inhibitors of nucleotide‐ and polyphosphate‐processing enzymes: A PPK1 and PPK2 case study

A. Joachimiak, B. Nocek, A. Yakunin, 2018, Chemical biology & drug design.

Evolution of plant δ1-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives

K. Makarova, G. Forlani, M. Bertazzini, 2015, Front. Plant Sci..

Structural basis for stereoselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases.

J. W. Peters, B. Nocek, Arathi M Krishnakumar, 2006, Biochemistry.

Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

J. W. Peters, A. Pandey, B. Nocek, 2006, Biochemistry.

δ1-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

A. Joachimiak, G. Forlani, B. Nocek, 2012, Amino Acids.

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids.

Radhakrishnan Mahadevan, Kevin Correia, R. Mahadevan, 2017, Biotechnology journal.

The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism

B. Nocek, P. Stogios, A. Savchenko, 2015, Nucleic acids research.

Screening and Characterization of Novel Polyesterases from Environmental Metagenomes with High Hydrolytic Activity against Synthetic Polyesters.

D. Le Paslier, A. Joachimiak, B. Nocek, 2018, Environmental science & technology.

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

A. Joachimiak, B. Nocek, A. Savchenko, 2016, Biomacromolecules.

Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

A. Joachimiak, B. Nocek, A. Savchenko, 2008, Proceedings of the National Academy of Sciences.

S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies.

M. Jaskólski, Z. Dauter, B. Nocek, 2017, International journal of biological macromolecules.

Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction*

B. Nocek, A. Yakunin, Greg Brown, 2013, The Journal of Biological Chemistry.

Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases

A. Joachimiak, M. Ruszkowski, B. Nocek, 2018, ACS Catalysis.

Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis

A. Joachimiak, F. Collart, B. Nocek, 2006, Proteins.

A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair

Andrew Emili, Mohan Babu, Eugene V Koonin, 2011, Molecular microbiology.

The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

A. Joachimiak, B. Nocek, T. Skarina, 2014, Nucleic acids research.

Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

Jürgen Pleiss, Rafael Bargiela, Manuel Ferrer, 2017, ACS chemical biology.

Crystal structures of delta1-pyrroline-5-carboxylate reductase from human pathogens Neisseria meningitides and Streptococcus pyogenes.

A. Joachimiak, F. Collart, B. Nocek, 2005, Journal of molecular biology.

Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.

A. Joachimiak, B. Nocek, D. Gillner, 2015, Biochemistry.

Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase.

A. Joachimiak, B. Nocek, D. Gillner, 2010, Journal of molecular biology.

Functional and structural diversity in GH62 α-L-arabinofuranosidases from the thermophilic fungus Scytalidium thermophilum

B. Nocek, P. Stogios, A. Savchenko, 2014, Microbial biotechnology.

Correction to Differential Stabilities and Sequence-Dependent Base Pair Opening Dynamics of Watson–Crick Base Pairs with 5-Hydroxymethylcytosine, 5-Formylcytosine, or 5-Carboxylcytosine

A. Joachimiak, M. Egli, B. Eichman, 2015, Biochemistry.

Differential Stabilities and Sequence-Dependent Base Pair Opening Dynamics of Watson–Crick Base Pairs with 5-Hydroxymethylcytosine, 5-Formylcytosine, or 5-Carboxylcytosine

Martin Egli, Surajit Banerjee, Michael P. Stone, 2015, Biochemistry.

A family of metal-dependent phosphatases implicated in metabolite damage-control.

Oliver Fiehn, John Shanklin, Rémi Zallot, 2016, Nature chemical biology.

Sugar phosphate activation of the stress sensor eIF2B

V. Stoll, S. Hackett, R. Jain, 2021, Nature Communications.

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

Alexei, A. Joachimiak, B. Nocek, 2016, Biomacromolecules.

Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation

J. W. Peters, B. Nocek, B. Eilers, 2017, Scientific Reports.

The structure of Medicago truncatula δ1-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants

Z. Dauter, G. Forlani, M. Ruszkowski, 2015, Front. Plant Sci..

Peculiar substrate specificity of δ1-pyrroline-5-carboxylate reductase in the obligately fermentative bacterium Zymomonas mobilis

G. Forlani, M. Ruszkowski, B. Nocek, 2021, Molecular Biology Reports.

EPR and X-ray Crystallographic Characterization of the Product-Bound Form of the Mn^II-Loaded Methionyl Aminopeptidase from Pyrococcus furiosus

J. W. Peters, B. Nocek, A. Copik, 2020 .

Structure of SO2946 orphan from Shewanella oneidensis shows “jelly-roll” fold with carbohydrate-binding module

A. Joachimiak, B. Nocek, L. Bigelow, 2008, Journal of Structural and Functional Genomics.

Large-scale evaluation of protein reductive methylation for improving protein crystallization

Youngchang Kim, T. Andrew Binkowski, Min Zhou, 2008, Nature Methods.

Structural and functional characterization of microcin C resistance peptidase MccF from Bacillus anthracis.

K. Makarova, A. Joachimiak, K. Severinov, 2012, Journal of molecular biology.

Resistance to Enediyne Antitumor Antibiotics by Sequestration.

B. Shen, G. Phillips, A. Joachimiak, 2018, Cell chemical biology.

Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

J. W. Peters, B. Nocek, S. Jang, 2002, Biochemistry.

Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis.

K. Nicolaou, B. Nocek, M. Aujay, 2021, The Journal of organic chemistry.

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids.

R. Mahadevan, B. Nocek, J. Joo, 2017, Biotechnology journal.

EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus.

B. Nocek, A. Copik, S. Jang, 2005, Biochemistry.

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

B. Nocek, P. Stogios, A. Savchenko, 2016, Molecular systems biology.

δ1-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

A. Joachimiak, G. Forlani, B. Nocek, 2011, Amino Acids.

Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

A. Joachimiak, B. Nocek, R. Jedrzejczak, 2018, Biochemistry.

Structural Evidence of a Major Conformational Change Triggered Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism Mechanism

B. Nocek, C. Reidl, 2022 .

B. Nocek, R. Jedrzejczak, J. Osipiuk, 2022 .