Manuel Simoes

发表

A gating mechanism of pentameric ligand-gated ion channels

Antoine Taly, Marco Cecchini, Martin Karplus, 2013, Proceedings of the National Academy of Sciences.

MCSS-Based Predictions of Binding Mode and Selectivity of Nucleotide Ligands.

Manuel Simoes, L. Montero-Cabrera, Fabrice Leclerc, 2021, Journal of chemical theory and computation.

The KCa3.1 Channel in Endothelial Cells as New Target for an EDHF-Based Control of Vascular Tone: From Structure to Regulation and Pharmacological Properties

R. Sauvé, Manuel Simoes, L. Garneau, 2008 .

The Role of the GX9GX3G Motif in the Gating of High Voltage-activated Ca2+ Channels*

R. Sauvé, Manuel Simoes, D. Bichet, 2006, Journal of Biological Chemistry.

A Single Residue in the S6 Transmembrane Domain Governs the Differential Flecainide Sensitivity of Voltage-Gated Potassium Channels

S. Nattel, R. Sauvé, Manuel Simoes, 2005, Molecular Pharmacology.

New Insights on the Voltage Dependence of the KCa3.1 Channel Block by Internal TBA

R. Sauvé, Manuel Simoes, L. Garneau, 2004, The Journal of general physiology.

Outer Pore Topology of the ECaC-TRPV5 Channel by Cysteine Scan Mutagenesis*

R. Sauvé, Manuel Simoes, G. Bernatchez, 2004, Journal of Biological Chemistry.

Structural Determinants of the Closed KCa3.1 Channel Pore in Relation to Channel Gating: Results from a Substituted Cysteine Accessibility Analysis

R. Sauvé, Manuel Simoes, L. Garneau, 2007, The Journal of general physiology.

Cysteine Mutagenesis and Computer Modeling of the S6 Region of an Intermediate Conductance IKCa Channel

R. Sauvé, B. Roux, Manuel Simoes, 2002, The Journal of general physiology.

New Insights on the Voltage Dependence of the KCa3.1 Channel Block by Internal TBA

R. Sauvé, Manuel Simoes, L. Garneau, 2004, The Journal of general physiology.