B. VanSchouwen

发表

Mapping allostery through the covariance analysis of NMR chemical shifts

Giuseppe Melacini, Rajeevan Selvaratnam, Bryan VanSchouwen, 2011, Proceedings of the National Academy of Sciences.

Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)*

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2011, The Journal of Biological Chemistry.

Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations

Miguel A. Soler, Miguel A Soler, B. VanSchouwen, 2015, PloS one.

Allosteric pluripotency: challenges and opportunities.

B. VanSchouwen, G. Melacini, M. Akimoto, 2022, The Biochemical journal.

Structural Basis of Tonic Inhibition by Dimers of Dimers in Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels.

B. VanSchouwen, G. Melacini, 2016, The journal of physical chemistry. B.

Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding.

B. VanSchouwen, G. Melacini, Stephen Boulton, 2020, Biophysical journal.

Polyglutamine monomer structure and its implications for molecular self-assembly

B. VanSchouwen, 2009 .

The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2012, Biophysical journal.

An auto-inhibited state of protein kinase G and implications for selective activation

B. Sankaran, B. VanSchouwen, G. Melacini, 2022, bioRxiv.

Allosteric inhibition explained through conformational ensembles sampling distinct “mixed” states

B. VanSchouwen, G. Melacini, M. Akimoto, 2020, Computational and structural biotechnology journal.

Allosteric pluripotency as revealed by protein kinase A

S. Taylor, B. VanSchouwen, G. Melacini, 2020, Science Advances.

Cracking the allosteric code of NMR chemical shifts

B. VanSchouwen, G. Melacini, 2016, Proceedings of the National Academy of Sciences.

Functional dynamics in cyclic nucleotide signaling and amyloid inhibition.

B. VanSchouwen, G. Melacini, J. Milojevic, 2017, Biochimica et biophysica acta. Proteins and proteomics.

Regulation of HCN Ion Channels by Non-canonical Cyclic Nucleotides.

B. VanSchouwen, G. Melacini, 2017, Handbook of experimental pharmacology.

A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP*

O. Lange, E. Accili, Rajeevan Selvaratnam, 2014, The Journal of Biological Chemistry.

Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases.

B. VanSchouwen, G. Melacini, M. Akimoto, 2022, Journal of molecular biology.

State-selective frustration as a key driver of allosteric pluripotency

Madoka Akimoto, Giuseppe Melacini, Jung Ah Byun, 2021, Chemical science.

Structure propensities in mutated polyglutamine peptides

S. M. Rothstein, B. VanSchouwen, Daniel G. Oblinsky, 2011, Interdisciplinary Sciences: Computational Life Sciences.

Identification of Core Allosteric Sites through Temperature- and Nucleus-Invariant Chemical Shift Covariance.

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2022, Biophysical journal.

cAMP-dependent allostery and dynamics in Epac: an NMR view.

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2012, Biochemical Society transactions.

Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)*♦

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2015, The Journal of Biological Chemistry.

Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.

J. Pflugrath, B. Sankaran, Rajeevan Selvaratnam, 2014, Structure.

Molecular Mechanism for the (-)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers.

J. Ortega, B. VanSchouwen, G. Melacini, 2017, Journal of the American Chemical Society.

Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR.

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2014, Biochemical Society transactions.

Water-mediated interactions in the CRP-cAMP-DNA complex: Does water mediate sequence-specific binding at the DNA primary-kink site?

Shigenori Tanaka, Yuto Komeiji, Kaori Fukuzawa, 2008, Comput. Biol. Chem..

Allosteric linkers in cAMP signalling.

Susan S. Taylor, Rajeevan Selvaratnam, B. VanSchouwen, 2014, Biochemical Society transactions.

The structure of the apo cAMP‐binding domain of HCN4 – a stepping stone toward understanding the cAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels

B. VanSchouwen, G. Melacini, M. Akimoto, 2018, The FEBS journal.

Crystal structure of cGMP‐dependent protein kinase Iβ cyclic nucleotide‐binding‐B domain : Rp‐cGMPS complex reveals an apo‐like, inactive conformation

James C. Campbell, B. Sankaran, B. VanSchouwen, 2017, FEBS letters.

Procrustean rotation in concert with principal component analysis of molecular dynamics trajectories: Quantifying global and local differences between conformational samples.

S. M. Rothstein, B. VanSchouwen, Daniel G. Oblinsky, 2009, The Journal of chemical physics.