Raj Kumar

发表

Host S-nitrosylation inhibits clostridial small molecule–activated glucosylating toxins

A. Hausladen, J. Stamler, W. Braun, 2011, Nature Medicine.

Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.

Raj Kumar, I. McEwan, 2012, Endocrine reviews.

Protein-Protein Interactions: Principles, Techniques, and their Potential Role in New Drug Development

Faizan Ahmad, Nihal Ahmad, F. Ahmad, 2011, Journal of biomolecular structure & dynamics.

Lipophilicity Indices for Drug Development

Raj Kumar, S. Planey, 2013 .

Trehalose induced conformational changes in the amyloid-β peptide.

Raj Kumar, Shagufta Khan, 2017, Pathology, research and practice.

Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor

Raj Kumar, Shagufta Khan, Anna S. Garza, 2009, Molecular and Cellular Biology.

Estrogen receptors (ERα versus ERβ): friends or foes in human biology?

Raj Kumar, S. Planey, J. A. Arnott, 2014, Journal of receptor and signal transduction research.

Binding of the N-terminal Region of Coactivator TIF2 to the Intrinsically Disordered AF1 Domain of the Glucocorticoid Receptor Is Accompanied by Conformational Reorganizations*

P. Griffin, Raj Kumar, Shagufta Khan, 2012, The Journal of Biological Chemistry.

Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: Distinct effect of progesterone receptor isoforms

Raj Kumar, M. Jamaluddin, A. Al-Hendy, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Resveratrol in cancer management: where are we and where we go from here?

Raj Kumar, N. Ahmad, M. Ndiaye, 2011, Annals of the New York Academy of Sciences.

Role of naturally occurring osmolytes in protein folding and stability.

Raj Kumar, 2009, Archives of biochemistry and biophysics.

Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review).

Raj Kumar, N. Ahmad, M. Aziz, 2003, International journal of oncology.

Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance.

Concepcion R. Diaz-Arrastia, T. Veenstra, Raj Kumar, 2009, The Journal of clinical endocrinology and metabolism.

Effect of TNF-α on Estrogen Metabolism and Endometrial Cells: Potential Physiological and Pathological Relevance

T. Veenstra, Raj Kumar, Xia Xu, 2009 .

An Overview of the Importance of Conformational Flexibility in Gene Regulation by the Transcription Factors

Raj Kumar, Shagufta Khan, 2010, Journal of biophysics.

Restored mutant receptor:Corticoid binding in chaperone complexes by trimethylamine N-oxide

Raj Kumar, W. A. Elam, Shagufta Khan, 2017, PloS one.

Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.

D. Edwards, Raj Kumar, S. Simons, 2014, Molecular endocrinology.

Site-Speciﬁc Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor (cid:1)

Raj Kumar, Anna M. S. Garza, Shagufta Khan, 2009 .

Diversity of the Biochemical and Biological Behavior of Platelet-Activating Factor

Raj Kumar, D. Hanahan, 1987 .

Forty years of research on osmolyte-induced protein folding and stability

F. Ahmad, Raj Kumar, T. Dar, 2011 .

Regulation of the Structurally Dynamic N-terminal Domain of Progesterone Receptor by Protein-induced Folding*

D. Edwards, P. Griffin, Raj Kumar, 2013, The Journal of Biological Chemistry.

CYCLIC AMP-DEPENDENT PROTEIN KINASES FROM RABBIT RED BLOOD CELLS: ACTIVATION, FUNCTION, AND MOLECULAR FORMS

Raj Kumar, M. Tao, P. Hackett, 1973 .

Protein and DNA destabilization by osmolytes: the other side of the coin.

Faizan Ahmad, F. Ahmad, Raj Kumar, 2011, Life sciences.

The Conformation of the Glucocorticoid Receptor AF1/tau1 Domain Induced by Osmolyte Binds Co-regulatory Proteins*

J. Lee, Raj Kumar, D. W. Bolen, 2001, The Journal of Biological Chemistry.

Trimethylamine N-Oxide-induced Cooperative Folding of an Intrinsically Unfolded Transcription-activating Fragment of Human Glucocorticoid Receptor*

I. Baskakov, Raj Kumar, D. W. Bolen, 1999, The Journal of Biological Chemistry.

An intrinsically disordered region of the transcription factor, NFAT5, becomes more ordered with an increase in osmolality (1182.8)

Raj Kumar, Y. Izumi, M. Burg, 2014 .

Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targeting

Raj Kumar, 2016, Asian journal of andrology.

Induced alpha-helix structure in AF1 of the androgen receptor upon binding transcription factor TFIIF.

Raj Kumar, I. McEwan, E. Thompson, 2004, Biochemistry.

A versatile method to measure the binding to basic proteins by surface plasmon resonance.

Raj Kumar, Shagufta Khan, Jun Ling, 2012, Analytical biochemistry.

Overview of the structural basis for transcription regulation by nuclear hormone receptors.

Raj Kumar, Betty H. Johnson, E. Thompson, 2004, Essays in biochemistry.

Role of Conformational Dynamics and Flexibilities in the Steroid Receptor- Coregulator Protein Complex Formation.

Raj Kumar, 2021, General and comparative endocrinology.

Interdomain Signaling in a Two-domain Fragment of the Human Glucocorticoid Receptor*

J. Lee, I. Baskakov, Raj Kumar, 1999, The Journal of Biological Chemistry.

Gene regulation by the glucocorticoid receptor: Structure:function relationship

Raj Kumar, E. Thompson, E. Thompson, 2005, The Journal of Steroid Biochemistry and Molecular Biology.

Glucocorticoid Receptor Structure and Function

Raj Kumar, I. McEwan, 2015 .

Activation of NFkB is a novel mechanism of pro-survival activity of glucocorticoids in breast cancer cells.

Raj Kumar, Shagufta Khan, Jun Ling, 2013, Cancer letters.

Novel downstream molecular targets of SIRT1 in melanoma: A quantitative proteomics approach

Raj Kumar, M. Nihal, N. Ahmad, 2014, Oncotarget.

Crosstalk between NFkB and glucocorticoid signaling: a potential target of breast cancer therapy.

Raj Kumar, Jun Ling, 2012, Cancer letters.

p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.

Raj Kumar, A. Copik, Betty H. Johnson, 2005, Molecular endocrinology.

Role of Phosphorylation in the Modulation of the Glucocorticoid Receptor’s Intrinsically Disordered Domain

Raj Kumar, E. Thompson, E. Thompson, 2019, Biomolecules.

Emerging role of glucocorticoid receptor in castration resistant prostate cancer: A potential therapeutic target

Raj Kumar, 2020, Journal of Cancer.

Role of intrinsically disordered protein regions/domains in transcriptional regulation.

Raj Kumar, N. Ahmad, Anna M. S. Garza, 2009, Life sciences.

The structure of the nuclear hormone receptors

Raj Kumar, E. Thompson, E. Thompson, 1999, Steroids.

Naturally occurring organic osmolytes: From cell physiology to disease prevention

F. Ahmad, Raj Kumar, N. Ahmad, 2010, IUBMB life.

Selenium and Vitamin E for Prostate Cancer: Post-SELECT (Selenium and Vitamin E Cancer Prevention Trial) Status

H. Mukhtar, Raj Kumar, B. Jung-Hynes, 2011, Molecular medicine.

Steroid hormone receptors in cancer development: a target for cancer therapeutics.

Raj Kumar, N. Ahmad, 2011, Cancer letters.

Activation function 1 of glucocorticoid receptor binds TATA-binding protein in vitro and in vivo.

Raj Kumar, A. Copik, Aaron L. Miller, 2006, Molecular endocrinology.

Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions.

Raj Kumar, E. Thompson, E. Thompson, 2003, Molecular endocrinology.

The Dynamic Structure of the Estrogen Receptor

Raj Kumar, S. Bhasin, Ravi Jasuja, 2011, Journal of amino acids.

Variable steroid receptor responses: Intrinsically disordered AF1 is the key

Raj Kumar, S. Simons, S. Stoney Simons, 2013, Molecular and Cellular Endocrinology.

TBP Binding-Induced Folding of the Glucocorticoid Receptor AF1 Domain Facilitates Its Interaction with Steroid Receptor Coactivator-1

Raj Kumar, Shagufta Khan, Jun Ling, 2011, PloS one.

Structural and functional relationships of the steroid hormone receptors’ N-terminal transactivation domain

Raj Kumar, G. Litwack, 2009, Steroids.

Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation

W. Calhoun, Raj Kumar, 2008, Biologics : targets & therapy.

Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy.

Raj Kumar, Shagufta Khan, 2012, Molecular bioSystems.

Binding-Folding Induced Regulation of AF1 Transactivation Domain of the Glucocorticoid Receptor by a Cofactor That Binds to Its DNA Binding Domain

D. Edwards, Raj Kumar, Shagufta Khan, 2011, PloS one.

Naturally Occurring Osmolyte, Trehalose Induces Functional Conformation in an Intrinsically Disordered Activation Domain of Glucocorticoid Receptor

Raj Kumar, Shagufta Khan, J. Arnott, 2011, PloS one.

TATA box binding protein induces structure in the recombinant glucocorticoid receptor AF1 domain.

D. Volk, D. Gorenstein, James C. Lee, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic

Raj Kumar, I. McEwan, 2015 .

Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry.

Patrick R. Griffin, D. Edwards, P. Griffin, 2014, Structure.

Role of androgen receptor polyQ chain elongation in Kennedy's disease and use of natural osmolytes as potential therapeutic targets

Raj Kumar, 2012, IUBMB life.

Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor

William A. McLaughlin, Raj Kumar, Shagufta Khan, 2017, Scientific Reports.

Nuclear Receptors: From Structure to the Clinic

Raj Kumar, I. McEwan, 2015, Springer International Publishing.

Differential susceptibility of mono- and ether phosphoglycerides to acetolysis di-0-al kyl

S. Weintraub, Raj Kumar, D. Hanahan, 1983 .

NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain

Raj Kumar, Shagufta Khan, E. Thompson, 2020, Proceedings of the National Academy of Sciences.

Trehalose induces functionally active conformation in the intrinsically disordered N-terminal domain of glucocorticoid receptor

Raj Kumar, Ravi Jasuja, Shagufta Khan, 2016, Journal of biomolecular structure & dynamics.

Osmolyte-Induced Folding of an Intrinsically Disordered Activation Function Subdomain of Glucocorticoid Receptor

Raj Kumar, 2008 .

Osmolyte-induced folding enhances tryptic enzyme activity.

Raj Kumar, E. Thompson, J. M. Serrette, 2005, Archives of biochemistry and biophysics.

DNA binding of nuclear hormone receptors influences their structure and function.

Raj Kumar, E. Thompson, E. Thompson, 2003, Biochemical and biophysical research communications.

Gene regulation by the steroid hormone receptors: new promises and challenges for therapeutic targeting

Raj Kumar, 2016 .

Influence of flanking sequences on signaling between the activation function AF1 and DNA-binding domain of the glucocorticoid receptor.

R. Kumar, Raj Kumar, E. Thompson, 2010, Archives of biochemistry and biophysics.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance.

Concepcion R. Diaz-Arrastia, T. Veenstra, Raj Kumar, 2009, The Journal of clinical endocrinology and metabolism.

Folding of the glucocorticoid receptor N-terminal transactivation function: Dynamics and regulation

Raj Kumar, E. Thompson, 2012, Molecular and Cellular Endocrinology.

Structural and functional relationships of the steroid hormone receptors’ N-terminal transactivation domain

Raj Kumar, G. Litwack, 2009, Steroids.

Dynamics of coregulator-induced conformational perturbations in androgen receptor ligand binding domain

A. Godzik, Raj Kumar, S. Bhasin, 2011, Molecular and Cellular Endocrinology.

Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry.

D. Edwards, P. Griffin, Raj Kumar, 2014, Structure.