B. Brutscher

发表

Direct observation of the dynamic process underlying allosteric signal transmission.

Paul Schanda, Martin Tollinger, Bernhard Brutscher, 2009, Journal of the American Chemical Society.

iNEXT: a European facility network to stimulate translational structural biology

J. Ellenberg, H. Schwalbe, D. Stuart, 2018, FEBS letters.

Highly Efficient NMR Assignment of Intrinsically Disordered Proteins: Application to B- and T Cell Receptor Domains

M. Mayzel, V. Orekhov, B. Brutscher, 2013, PloS one.

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex

M. Blackledge, M. R. Jensen, B. Brutscher, 2009, Nucleic acids research.

Band-selective hetero- and homonuclear cross-polarization using trains of shaped pulses

B. Brutscher, E. Zuiderweg, R. C. Morshauser, 1996, Journal of biomolecular NMR.

Méthodes d'acquisition rapide de spectres RMN multidimensionnels. Application à l'étude structurale de protéines.

B. Brutscher, 2005 .

Guidelines for the use of band-selective radiofrequency pulses in hetero-nuclear NMR: example of longitudinal-relaxation-enhanced BEST-type 1H-15N correlation experiments.

B. Brutscher, E. Lescop, T. Kern, 2010, Journal of magnetic resonance.

Spectral editing of intra- and inter-chain methyl–methyl NOEs in protein complexes

P. Gans, J. Boisbouvier, B. Brutscher, 2020, Journal of Biomolecular NMR.

Backbone dynamics and structural characterization of the partially folded A state of ubiquitin by 1H, 13C, and 15N nuclear magnetic resonance spectroscopy.

R. Brüschweiler, R. R. Ernst, B. Brutscher, 1997, Biochemistry.

Measuring hydrogen exchange in proteins by selective water saturation in 1H–15N SOFAST/BEST-type experiments: advantages and limitations

B. Brutscher, E. Rennella, Zsófia Sólyom, 2014, Journal of biomolecular NMR.

UltraSOFAST HMQC NMR and the repetitive acquisition of 2D protein spectra at Hz rates.

P. Schanda, L. Frydman, B. Brutscher, 2007, Journal of the American Chemical Society.

How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine

C. Chipot, Rémy Sounier, P. Schanda, 2018, The journal of physical chemistry letters.

Suppression of artifacts induced by homonuclear decoupling in amino-acid-type edited methyl 1H-13C correlation experiments.

J. Simorre, B. Brutscher, H. Van Melckebeke, 2004, Journal of magnetic resonance.

Highly automated protein backbone resonance assignment within a few hours: the «BATCH» strategy and software package

B. Brutscher, E. Lescop, 2009, Journal of biomolecular NMR.

HNCA+, HNCO+, and HNCACB+ experiments: improved performance by simultaneous detection of orthogonal coherence transfer pathways

B. Brutscher, A. Favier, S. Gil-Caballero, 2014, Journal of Biomolecular NMR.

Base-type-selective high-resolution 13C edited NOESY for sequential assignment of large RNAs

J. Boisbouvier, E. Kupče, J. Simorre, 2001, Journal of biomolecular NMR.

Automated spectral compression for fast multidimensional NMR and increased time resolution in real-time NMR spectroscopy.

P. Schanda, B. Brutscher, E. Lescop, 2007, Journal of the American Chemical Society.

Rapid measurement of residual dipolar couplings for fast fold elucidation of proteins

J. Boisbouvier, B. Brutscher, E. Lescop, 2011, Journal of biomolecular NMR.

Evidence for a dimerisation state of the Bacillus subtilis catabolite repression HPr-like protein, Crh.

F. Penin, D. Marion, B. Brutscher, 2001, Journal of molecular microbiology and biotechnology.

Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface

S. Cusack, B. Brutscher, M. Lethier, 2022, bioRxiv.

NMR structure of the cathelin-like domain of the protegrin-3 precursor.

M. Strub, B. Brutscher, A. Aumelas, 2003, Biochemistry.

Structural Changes of Escherichia coli Ferric Uptake Regulator during Metal-dependent Dimerization and Activation Explored by NMR and X-ray Crystallography*

J. Dupuy, B. Brutscher, L. Jacquamet, 2006, Journal of Biological Chemistry.

NMRlib: user-friendly pulse sequence tools for Bruker NMR spectrometers

B. Brutscher, A. Favier, Adrien Favier, 2019, Journal of Biomolecular NMR.

BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins

R. Konrat, B. Brutscher, D. Willbold, 2013, Journal of Biomolecular NMR.

The plasma membrane-associated cation-binding protein PCaP1 of Arabidopsis thaliana is a uranyl-binding protein.

S. Ravanel, B. Brutscher, J. Armengaud, 2022, Journal of Hazardous Materials.

Intraresidue HNCA and COHNCA experiments for protein backbone resonance assignment.

B. Brutscher, 2002, Journal of magnetic resonance.

NMR spectroscopic studies of intrinsically disordered proteins at near-physiological conditions.

B. Brutscher, I. Felli, R. Pierattelli, 2013, Angewandte Chemie.

ssNMRlib: a comprehensive library and tool box for acquisition of solid-state nuclear magnetic resonance experiments on Bruker spectrometers

P. Schanda, B. Brutscher, A. Favier, 2020, Magnetic Resonance.

ssNMRlib: a comprehensive library and tool box for acquisition of solid-state nuclear magnetic resonance experiments on Bruker spectrometers

Paul Schanda, Alicia Vallet, Adrien Favier, 2020, Magnetic resonance.

Measuring hydrogen exchange in proteins by selective water saturation in 1H–15N SOFAST/BEST-type experiments: advantages and limitations

B. Brutscher, E. Rennella, Zsófia Sólyom, 2014, Journal of Biomolecular NMR.

HNCA+, HNCO+, and HNCACB+ experiments: improved performance by simultaneous detection of orthogonal coherence transfer pathways

B. Brutscher, A. Favier, S. Gil-Caballero, 2014, Journal of Biomolecular NMR.

iHADAMAC: a complementary tool for sequential resonance assignment of globular and highly disordered proteins.

B. Brutscher, D. Willbold, M. Plevin, 2012, Journal of magnetic resonance.

Sensitivity-optimized experiment for the measurement of residual dipolar couplings between amide protons

Rémy Sounier, J. Boisbouvier, P. Schanda, 2007, Journal of biomolecular NMR.

HET‐SOFAST NMR for fast detection of structural compactness and heterogeneity along polypeptide chains

P. Schanda, B. Brutscher, V. Forge, 2006, Magnetic resonance in chemistry : MRC.

Hadamard frequency-encoded SOFAST-HMQC for ultrafast two-dimensional protein NMR.

P. Schanda, B. Brutscher, 2006, Journal of magnetic resonance.

SOFAST-HMQC Experiments for Recording Two-dimensional Deteronuclear Correlation Spectra of Proteins within a Few Seconds

Paul Schanda, Bernhard Brutscher, Ēriks Kupče, 2005, Journal of biomolecular NMR.

Resolution-Enhanced Base-Type-Edited HCN Experiment for RNA

A. Pardi, J. Boisbouvier, J. Simorre, 2005, Journal of biomolecular NMR.

Protein Structure and Dynamics by NMR in Solution

M. Blackledge, D. Marion, B. Brutscher, 2000 .

Solution structure, rotational diffusion anisotropy and local backbone dynamics of Rhodobacter capsulatus cytochrome c2.

M. Blackledge, D. Marion, B. Brutscher, 1998, Journal of molecular biology.

Oligomeric states along the folding pathways of β2-microglobulin: kinetics, thermodynamics, and structure.

B Brutscher, I. Ayala, P. Schanda, 2013, Journal of molecular biology.

Real-time NMR characterization of structure and dynamics in a transiently populated protein folding intermediate.

Paul Schanda, Bernhard Brutscher, I. Ayala, 2012, Journal of the American Chemical Society.

Recovering lost magnetization: polarization enhancement in biomolecular NMR

B. Brutscher, A. Favier, 2011, Journal of biomolecular NMR.

Protein folding and unfolding studied at atomic resolution by fast two-dimensional NMR spectroscopy

Paul Schanda, Bernhard Brutscher, P. Schanda, 2007, Proceedings of the National Academy of Sciences.

A set of BEST triple-resonance experiments for time-optimized protein resonance assignment.

P. Schanda, B. Brutscher, E. Lescop, 2007, Journal of magnetic resonance.

Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds.

Paul Schanda, Bernhard Brutscher, P. Schanda, 2005, Journal of the American Chemical Society.

Rapid Multidimensional NMR: Fast‐Pulsing Techniques and their Applications to Proteins

P. Schanda, B. Brutscher, 2009 .

Speeding up three-dimensional protein NMR experiments to a few minutes.

Paul Schanda, Bernhard Brutscher, P. Schanda, 2006, Journal of the American Chemical Society.

Solution structure of the sulfite reductase flavodoxin-like domain from Escherichia coli.

M. Blackledge, J. Covès, B. Brutscher, 2005, Biochemistry.

Direct structure determination using residual dipolar couplings: reaction-site conformation of methionine sulfoxide reductase in solution.

Frédéric Barras, Martin Blackledge, Bernhard Brutscher, 2002, Journal of the American Chemical Society.

Amino acid-type edited NMR experiments for methyl-methyl distance measurement in 13C-labeled proteins.

J. Simorre, B. Brutscher, H. Van Melckebeke, 2004, Journal of the American Chemical Society.

BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins

R. Konrat, B. Brutscher, D. Willbold, 2013, Journal of biomolecular NMR.

Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids in solution.

A. Pardi, J. Boisbouvier, P. Schanda, 2009, Journal of the American Chemical Society.

NMR study of the interaction between Zn(II) ligated bleomycin and Streptoalloteichus hindustanus bleomycin resistance protein.

M. Blackledge, D. Marion, J. Masson, 2003, Biochemistry.

Transverse relaxation optimized HCN experiment for nucleic acids: Combining the advantages of TROSY and MQ spin evolution

J. Simorre, B. Brutscher, 2001, Journal of biomolecular NMR.

Improved Sensitivity and Resolution in 1 H- 13 C NMR Experiments of RNA

A. Pardi, J. Boisbouvier, J. Simorre, 1998 .

Design of a Complete Set of Two-Dimensional Triple-Resonance Experiments for Assigning Labeled Proteins

J. Simorre, D. Marion, B. Brutscher, 1994 .

Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein.

M. Blackledge, R. Ruigrok, B. Brutscher, 2008, Journal of molecular biology.

Interaction of nonstructural protein 5A of the hepatitis C virus with Src homology 3 domains using noncanonical binding sites.

Bernhard Brutscher, Zsofia Solyom, Dieter Willbold, 2013, Biochemistry.

Transient structure and SH3 interaction sites in an intrinsically disordered fragment of the hepatitis C virus protein NS5A.

B. Brutscher, D. Willbold, M. Schwarten, 2012, Journal of molecular biology.

Parallel screening and optimization of protein constructs for structural studies

J. Boisbouvier, T. Vernet, L. Blanchard, 2009, Protein science : a publication of the Protein Society.

RNA binding and chaperone activity of the E. coli cold-shock protein CspA

I. Ayala, P. Schanda, R. Konrat, 2017, Nucleic acids research.

Selective Isotopic Unlabeling of Proteins Using Metabolic Precursors: Application to NMR Assignment of Intrinsically Disordered Proteins

B. Brutscher, Rodolfo M. Rasia, M. Plevin, 2012, Chembiochem : a European journal of chemical biology.

Fast two-dimensional NMR spectroscopy of high molecular weight protein assemblies.

I. Ayala, J. Boisbouvier, P. Schanda, 2009, Journal of the American Chemical Society.

NMR Methods for the Study of Instrinsically Disordered Proteins Structure, Dynamics, and Interactions: General Overview and Practical Guidelines.

B. Brutscher, I. Felli, R. Pierattelli, 2015, Advances in experimental medicine and biology.

Letter to the Editor: 1H, 13C, and 15N assignment of a bleomycin resistance protein in its native form and in a complex with Zn2+ ligated bleomycin

D. Marion, J. Masson, B. Brutscher, 2000, Journal of biomolecular NMR.

The Disordered Region of the HCV Protein NS5A: Conformational Dynamics, SH3 Binding, and Phosphorylation.

B. Brutscher, G. Durand, A. Polidori, 2015, Biophysical journal.

Biophysical characterization of the MerP-like amino-terminal extension of the mercuric reductase from Ralstonia metallidurans CH34

M. Blackledge, J. Covès, B. Brutscher, 2003, JBIC Journal of Biological Inorganic Chemistry.

Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr.

M. Blackledge, F. Penin, D. Marion, 2002, Journal of molecular biology.

Principles and applications of cross-correlated relaxation in biomolecules

B. Brutscher, 2000 .

Spectral editing of intra- and inter-chain methyl–methyl NOEs in protein complexes

P. Gans, J. Boisbouvier, B. Brutscher, 2020, Journal of Biomolecular NMR.

Assignment of the 13C and 13CO resonances for Rhodobacter capsulatus ferrocytochrome c2 using double-resonance and triple-resonance NMR spectroscopy.

J. Simorre, D. Marion, B. Brutscher, 1994, European journal of biochemistry.

Solution structure of the C-terminal N-RNA binding domain of the Vesicular Stomatitis Virus Phosphoprotein

M. Blackledge, R. Ruigrok, B. Brutscher, 2008 .

Visualizing the transiently populated closed-state of human HSP90 ATP binding domain

P. Gans, J. Boisbouvier, M. Frech, 2022, bioRxiv.

BEST and SOFAST experiments for resonance assignment of histidine and tyrosine side chains in 13C/15N labeled proteins

B. Brutscher, N. E. Christou, 2018, Journal of Biomolecular NMR.

BEST and SOFAST experiments for resonance assignment of histidine and tyrosine side chains in 13C/15N labeled proteins

B. Brutscher, N. E. Christou, 2018, Journal of Biomolecular NMR.

Recent advances in solution NMR: fast methods and heteronuclear direct detection.

Bernhard Brutscher, B. Brutscher, I. Felli, 2009, Chemphyschem : a European journal of chemical physics and physical chemistry.

13C-labeled heparan sulfate analogue as a tool to study protein/heparan sulfate interactions by NMR spectroscopy: application to the CXCL12α chemokine.

P. Gans, A. Imberty, J. Simorre, 2011, Journal of the American Chemical Society.

Probing Conformational Exchange Dynamics in a Short-Lived Protein Folding Intermediate by Real-Time Relaxation-Dispersion NMR.

I. Ayala, B. Brutscher, A. Favier, 2017, Journal of the American Chemical Society.

NMRlib: user-friendly pulse sequence tools for Bruker NMR spectrometers

B. Brutscher, A. Favier, 2019, Journal of biomolecular NMR.

Hyperdimensional protein NMR spectroscopy in peptide-sequence space.

Bernhard Brutscher, B. Brutscher, E. Lescop, 2007, Journal of the American Chemical Society.

NMR Determination of Sugar Puckers in Nucleic Acids from CSA−Dipolar Cross-Correlated Relaxation

A. Pardi, J. Boisbouvier, J. Simorre, 2000 .

Fast protein backbone NMR resonance assignment using the BATCH strategy.

B. Brutscher, E. Lescop, 2012, Methods in molecular biology.

Optimized set of two-dimensional experiments for fast sequential assignment, secondary structure determination, and backbone fold validation of 13C/15N-labelled proteins

J. Covès, B. Brutscher, Emmanuel Rossy, 2003, Journal of biomolecular NMR.

“CON-CON” assignment strategy for highly flexible intrinsically disordered proteins

B. Brutscher, I. Felli, R. Pierattelli, 2014, Journal of biomolecular NMR.

NMR reveals light-induced changes in the dynamics of a photoswitchable fluorescent protein

I. Ayala, V. Adam, D. Bourgeois, 2019, bioRxiv.

Measurement of 13Cα-13CO cross-relaxation rates in 15N-/13C-labelled proteins

D. Marion, B. Brutscher, F. Cordier, 1996, Journal of biomolecular NMR.

Native-unlike Long-lived Intermediates along the Folding Pathway of the Amyloidogenic Protein β2-Microglobulin Revealed by Real-time Two-dimensional NMR*

P. Schanda, L. Frydman, B. Brutscher, 2009, The Journal of Biological Chemistry.

NMR assignment of Rhodobacter capsulatus ferricytochrome c', a 28 kDa paramagnetic heme protein.

B Brutscher, J. Simorre, D. Marion, 1995, Biochemistry.

1H, 13C, 15N-NMR resonance assignments of oxidized thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii using new methods based on two-dimensional triple-resonance NMR spectroscopy and computer-assisted backbone assignment.

J. Simorre, D. Marion, B. Brutscher, 1995, European journal of biochemistry.

1H and 13C NMR assignments and structural aspects of a ferrocytochrome c-551 from the purple phototrophic bacterium Ectothiorhodospira halophila.

D. Marion, T. Meyer, B. Brutscher, 1995, European journal of biochemistry.

Disentangling Chromophore States in a Reversibly Switchable Green Fluorescent Protein: Mechanistic Insights from NMR Spectroscopy.

I. Ayala, V. Adam, D. Bourgeois, 2021, Journal of the American Chemical Society.

Resolution enhancement in multidimensional solid-state NMR spectroscopy of proteins using spin-state selection.

Lyndon Emsley, Bernhard Brutscher, Anja Böckmann, 2003, Journal of the American Chemical Society.

Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing 2D NMR with reduced radiofrequency load.

P. Schanda, B. Brutscher, T. Kern, 2008, Journal of magnetic resonance.

Combined frequency- and time-domain NMR spectroscopy. Application to fast protein resonance assignment

B. Brutscher, 2004, Journal of biomolecular NMR.

DEPT spectral editing in HCCONH-type experiments. Application to fast protein backbone and side chain assignment.

B. Brutscher, 2004, Journal of magnetic resonance.

Time-resolved observation of spin waves in a linear chain of nuclear spins

Rafael Brüschweiler, Richard R. Ernst, R. Brüschweiler, 1997 .

Long-Range Structural Information in NMR Studies of Paramagnetic Molecules from Electron Spin−Nuclear Spin Cross-Correlated Relaxation

P. Gans, J. Boisbouvier, M. Blackledge, 1999 .

Aromatic SOFAST-HMBC for proteins at natural 13C abundance.

B. Brutscher, A. Favier, Alicia Vallet, 2019, Journal of magnetic resonance.

NMR assignments of human linker histone H1x N-terminal domain and globular domain in the presence and absence of perchlorate

B. Brutscher, G. Koorsen, Alicia Vallet, 2019, Biomolecular NMR assignments.

NMR assignments of human linker histone H1x N-terminal domain and globular domain in the presence and absence of perchlorate

B. Brutscher, G. Koorsen, Alicia Vallet, 2019, Biomolecular NMR Assignments.

Longitudinal relaxation properties of (1)H(N) and (1)H(α) determined by direct-detected (13)C NMR experiments to study intrinsically disordered proteins (IDPs).

B. Brutscher, I. Felli, R. Pierattelli, 2015, Journal of magnetic resonance.

Folding of the KIX domain: characterization of the equilibrium analog of a folding intermediate using 15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy.

P. Schanda, R. Konrat, M. Tollinger, 2008, Journal of molecular biology.

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface

B. Brutscher, M. Lethier, M. Hons, 2023, Life Science Alliance.

Optimization of multidimensional NMR using band-selective pulses

J. Simorre, D. Marion, B. Brutscher, 1992 .

Fast real-time NMR methods for characterizing short-lived molecular states.

B. Brutscher, E. Rennella, 2013, Chemphyschem : a European journal of chemical physics and physical chemistry.

Speeding up Multidimensional NMR Data Acquisition

Bernhard Brutscher, Dominique Marion, Lucio Frydman, 2012 .

Determination of an Initial Set of NOE-Derived Distance Constraints for the Structure Determination of15N/13C-Labeled Proteins

B. Brutscher, F. Cordier, Dominique Marion, 1995 .

High-resolution 3D HNCOCA experiment applied to a 28 kDa paramagnetic protein

J. Simorre, D. Marion, B. Brutscher, 1995, Journal of biomolecular NMR.

Computer assignment of the backbone resonances of labelled proteins using two-dimensional correlation experiments

J. Simorre, B. Brutscher, Dominique Marion, 1995, Journal of biomolecular NMR.

Assignment of NMR spectra of proteins using triple-resonance two-dimensional experiments

B Brutscher, J. Simorre, D. Marion, 1994, Journal of biomolecular NMR.

Optimized fast mixing device for real-time NMR applications.

P. Schanda, B. Brutscher, A. Favier, 2017, Journal of magnetic resonance.

Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment.

B. Brutscher, E. Lescop, Rodolfo M. Rasia, 2008, Journal of the American Chemical Society.

Resolution enhancement in multidimensional solid-state NMR spectroscopy of proteins using spin-state selection.

B. Brutscher, L. Duma, L. Emsley, 2003, Journal of the American Chemical Society.

Quantitative investigation of dipole-CSA cross-correlated relaxation by ZQ/DQ spectroscopy.

B. Brutscher, T. Bremi, Nikolai R. Skrynnikov, 1998, Journal of magnetic resonance.

Side chain orientation from methyl 1H-1H residual dipolar couplings measured in highly deuterated proteins.

M. Blackledge, J. Covès, B. Brutscher, 2002, Journal of the American Chemical Society.

An improved ultrafast 2D NMR experiment: Towards atom-resolved real-time studies of protein kinetics at multi-Hz rates

P. Schanda, L. Frydman, B. Brutscher, 2009, Journal of biomolecular NMR.

13C spin relaxation measurements in RNA: Sensitivity and resolution improvement using spin-state selective correlation experiments

J. Boisbouvier, J. Simorre, D. Marion, 1999 .

Direct observation of the dynamic process underlying allosteric signal transmission.

P. Schanda, R. Konrat, K. Kloiber, 2009, Journal of the American Chemical Society.

Selective Isotopic Unlabeling of Proteins Using Metabolic Precursors: Application to NMR Assignment of Intrinsically Disordered Proteins

B. Brutscher, Rodolfo M. Rasia, M. Plevin, 2012, Chembiochem : a European journal of chemical biology.

Oligomeric states along the folding pathways of β2-microglobulin: kinetics, thermodynamics, and structure.

P. Schanda, B. Brutscher, A. Corazza, 2013, Journal of molecular biology.

Anisotropic Intramolecular Backbone Dynamics of Ubiquitin Characterized by NMR Relaxation and MD Computer Simulation

S. F. Lienin, R. Brüschweiler, R. R. Ernst, 1998 .