Kaoru Tanaka

M. Fukuoka, Kaoru Tanaka, H. Yoon, 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Report of two cases of pseudoprogression in patients with non-small cell lung cancer treated with nivolumab-including histological analysis of one case after tumor regression.

Kaoru Tanaka, J. Tanizaki, K. Nakagawa, 2016, Lung cancer.

Phase I study of amatuximab, a novel monoclonal antibody to mesothelin, in Japanese patients with advanced solid tumors

Kaoru Tanaka, T. Kudo, I. Okamoto, 2014, Investigational New Drugs.

Successful long-term treatment with pemetrexed of NSCLC associated with EML4-ALK and low thymidylate synthase expression.

Kaoru Tanaka, K. Nishio, I. Okamoto, 2012, Clinical lung cancer.

Enhancement of radiosensitivity of MCF-7 breast cancer cells subjected to X-ray or carbon-ion irradiations

B. Wang, Kaoru Tanaka, Hong Zhang, 2016 .

Reduction of Delayed Homologous Recombination by Induction of Radioadaptive Response in RaDR-GFP Mice (Yonezawa Effect): An Old Player With a New Role

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2019, Dose-response : a publication of International Hormesis Society.

Afatinib-refractory brain metastases from EGFR-mutant non-small-cell lung cancer successfully controlled with erlotinib: a case report.

Toshio Shimizu, Kaoru Tanaka, K. Okamoto, 2016, Anti-cancer drugs.

Direct detection of p53−/− thymocyte appearing at an early stage of radiation-induced thymic lymphomagenesis in p53+/− heterozygous B10 mice

Kaoru Tanaka, M. Mori, Kazuko Yoshida, 2007, International journal of radiation biology.

mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.

N. Saijo, Kaoru Tanaka, K. Nishio, 2009, Cancer research.

Proline Decreases the Suppressive Effect of Histidine on Food Intake and Fat Accumulation.

N. Kanzawa, Kaoru Tanaka, T. J. Fujimi, 2016, Journal of nutritional science and vitaminology.

Total-body low-dose irradiation of mice induces neither learning disability and memory impairment in Morris water maze test nor Alzheimer's disease-like pathogensis in the brain

B. Wang, T. Ono, T. Suhara, 2014, Journal of Radiation Research.

Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck.

Kaoru Tanaka, T. Akimoto, T. Ogawa, 2020, Japanese journal of clinical oncology.

Vanadate:A Novel Type of Radioprotector Acts by Inhibiting p53.

W. Bing, A. Morita, Kaoru Tanaka, 2010 .

Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts

Kaoru Tanaka, K. Nishio, K. Nakagawa, 2020, British Journal of Cancer.

Effects of chronic restraint-induced stress on radiation-induced chromosomal aberrations in mouse splenocytes.

B. Wang, A. Morita, Kaoru Tanaka, 2017, Mutation research.

Phase I pharmacokinetic study of S-1 granules and nedaplatin for advanced head and neck cancer.

Y. Nishimura, Kaoru Tanaka, T. Satoh, 2013, Anticancer research.

Risk Factors for Cisplatin-Induced Nephrotoxicity and Potential of Magnesium Supplementation for Renal Protection

Kaoru Tanaka, K. Okamoto, K. Nakagawa, 2014, PloS one.

Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to X-rays.

B. Wang, Kaoru Tanaka, M. Nenoi, 2011, Mutation research.

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse.

B. Wang, Kaoru Tanaka, Y. Akasaka, 2012, Immunology letters.

SRPX2 Is a Novel Chondroitin Sulfate Proteoglycan That Is Overexpressed in Gastrointestinal Cancer

Kaoru Tanaka, K. Nishio, K. Yanagihara, 2012, PloS one.

SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion

Kaoru Tanaka, H. Yokote, K. Nishio, 2009, International journal of cancer.

Pharmacokinetics of amrubicin in lung cancer patients with impaired hepatic function

M. Fukuoka, K. Kiura, T. Kurihara, 2016 .

Reduced High-Dose Radiation-Induced Residual Genotoxic Damage by Induction of Radioadaptive Response and Prophylactic Mild Dietary Restriction in Mice

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2021, Dose-response : a publication of International Hormesis Society.

Mechanisms of primary and acquired resistance to immune checkpoint inhibitors in advanced non-small cell lung cancer: A multiplex immunohistochemistry-based single-cell analysis.

Kaoru Tanaka, K. Nishio, K. Nakagawa, 2022, Lung cancer.

Molecular Mechanisms of Radioadaptive Responses in Human Lymphoblastoid Cells

B. Wang, Kaoru Tanaka, M. Nenoi, 2008 .

Effects of prenatal irradiation with accelerated heavy-ion beams on postnatal development in rats: III. Testicular development and breeding activity

Kaoru Tanaka, H. Coffigny, S. G. Moreno, 2007 .

Effects of prenatal irradiation with an accelerated heavy-ion beam on postnatal development in rats: II. Further study on neurophysiologic alterations

Kaoru Tanaka, B. Wang, H. Coffigny, 2006 .

Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2018, Dose-response : a publication of International Hormesis Society.

Characteristic Pattern of Reactivation of Hepatitis B Virus during Chemotherapy for Solid Cancers

M. Kudo, Y. Minami, S. Kitai, 2012, Digestive Diseases.

Phase I/II Study of Cisplatin plus Nab-Paclitaxel with Concurrent Thoracic Radiotherapy for Patients with Locally Advanced Non-Small Cell Lung Cancer.

Kaoru Tanaka, Y. Hasegawa, J. Tanizaki, 2020, The Oncologist.

Effect of Hyperthermia and X-Irradiations on the Incidence of Metastasis of Transplanted B16 Melanoma in Mice

Kaoru Tanaka, A. Tsuboi, T. Furuse, 1986 .

Gene silencing of Tead3 abrogates radiation-induced adaptive response in cultured mouse limb bud cells.

B. Wang, Kaoru Tanaka, M. Nenoi, 2011, Journal of radiation research.

More efficient induction of genotoxicity by high-LET Fe-particle radiation than low-LET X-ray radiation at low doses

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2022, Radiation Medicine and Protection.

N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

C. Shimizu, Y. Fujiwara, Kaoru Tanaka, 2008, Cancer science.

HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non–Small Cell Lung Cancer

Kaoru Tanaka, K. Nishio, A. Tsuya, 2021, Clinical Cancer Research.

Clinical characteristics of non-small cell lung cancer harboring mutations in exon 20 of EGFR or HER2

Kaoru Tanaka, K. Nishio, J. Tanizaki, 2018, Oncotarget.

Impact of EGFR-TKI Treatment on the Tumor Immune Microenvironment in EGFR Mutation–Positive Non–Small Cell Lung Cancer

S. Tomida, Kaoru Tanaka, Y. Fukuda, 2020, Clinical Cancer Research.

FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth.

Kaoru Tanaka, M. D. De Velasco, K. Nishio, 2010, Cancer research.

Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer (JCOG1008): A Multicenter, Noninferiority, Phase II/III Randomized Controlled Trial

Y. Nishimura, Kaoru Tanaka, K. Shiga, 2022, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Safety and efficacy of cetuximab-containing chemotherapy after immune checkpoint inhibitors for patients with squamous cell carcinoma of the head and neck: a single-center retrospective study

Y. Nishimura, Kaoru Tanaka, K. Doi, 2020, Anti-cancer drugs.

Sodium orthovanadate inhibits p53-mediated apoptosis.

Shin Aoki, Y. Hosoi, Y. Matsumoto, 2010, Cancer research.

Enhanced Effects of Chronic Restraint-Induced Psychological Stress on Total Body Fe-Irradiation-Induced Hematopoietic Toxicity in Trp53-Heterozygous Mice

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2022, Life.

TAK-701, a Humanized Monoclonal Antibody to Hepatocyte Growth Factor, Reverses Gefitinib Resistance Induced by Tumor-Derived HGF in Non–Small Cell Lung Cancer with an EGFR Mutation

Wataru Okamoto, Masahiro Fukuoka, Kazuhiko Nakagawa, 2010, Molecular Cancer Therapeutics.

Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI

Kaoru Tanaka, K. Nishio, K. Doi, 2019, Oncogenesis.

Imaging and clinicopathological features of nivolumab-related cholangitis in patients with non-small cell lung cancer

M. Kudo, M. Takenaka, Kaoru Tanaka, 2017, Investigational New Drugs.

Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations.

Kaoru Tanaka, K. Nishio, I. Okamoto, 2010, Cancer research.

Chronic effects of methylmercury on the cerebral function in rats

S. Tobimatsu, Y. Goto, Kaoru Tanaka, 2000, Journal of the Neurological Sciences.

Effects of Prenatal Irradiation with an Accelerated Heavy-Ion Beam on Postnatal Development in Rats: I. Neurophysiological Alterations

B. Wang, Kaoru Tanaka, H. Coffigny, 2005, Radiation research.

Peripheral Blood Biomarkers Associated with Clinical Outcome in Non–Small Cell Lung Cancer Patients Treated with Nivolumab

Kaoru Tanaka, Y. Hasegawa, J. Tanizaki, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Adaptive response of low linear energy transfer X-rays for protection against high linear energy transfer accelerated heavy ion-induced teratogenesis.

B. Wang, Kaoru Tanaka, M. Nenoi, 2012, Birth defects research. Part B, Developmental and reproductive toxicology.

Adaptive Response in Embryogenesis: V. Existence of Two Efficient Dose-Rate Ranges for 0.3 Gy of Priming Irradiation to Adapt Mouse Fetuses

B. Wang, Kaoru Tanaka, H. Ohyama, 2004, Radiation research.

Trp53 activity is repressed in radio-adapted cultured murine limb bud cells.

B. Wang, Kaoru Tanaka, M. Nenoi, 2011, Journal of radiation research.

Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to low doses of heavy-ion radiation.

Kaoru Tanaka, M. Nenoi, G. Vares, 2011 .

X-Ray-Induced Radioresistance against High-LET Radiations from Accelerated Heavy Ions in Mice

B. Wang, Kaoru Tanaka, M. Nenoi, 2010, Radiation research.

B7-H3 Negatively Modulates CTL-Mediated Cancer Immunity

Kaoru Tanaka, K. Nishio, Y. Hasegawa, 2018, Clinical Cancer Research.

TGF-β induces sustained upregulation of SNAI1 and SNAI2 through Smad and non-Smad pathways in a human corneal epithelial cell line.

Koji Sugioka, Yoshikazu Shimomura, Daisuke Tamura, 2011, Investigative ophthalmology & visual science.

Complex renal cysts associated with crizotinib treatment

A. Shaw, Weiwei Tan, K. Wilner, 2015, Cancer medicine.

Cell Lung Cancer Small − Positive Non − Resistance to ALK Inhibitors in EML 4-ALK Activation of HER Family Signaling as a Mechanism of Acquired

Kaoru Tanaka, K. Nishio, I. Okamoto, 2013 .

The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer

Kaoru Tanaka, K. Nishio, I. Okamoto, 2015, Oncotarget.

Heregulin expression and its clinical implication for patients with EGFR-mutant non-small cell lung cancer treated with EGFR-tyrosine kinase inhibitors

Kaoru Tanaka, K. Nishio, K. Azuma, 2019, Scientific Reports.

DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruption

B. Wang, Kaoru Tanaka, Hong Zhang, 2013, PloS one.

Impact of coexisting gene mutations in EGFR-mutated non-small cell lung cancer before treatment on EGFR T790M mutation status after EGFR-TKIs.

Kaoru Tanaka, K. Nishio, K. Nakagawa, 2019, Lung cancer.

Tumor tissue and plasma levels of AXL and GAS6 before and after tyrosine kinase inhibitor treatment in EGFR‐mutated non–small cell lung cancer

Kaoru Tanaka, K. Azuma, K. Nakagawa, 2019, Thoracic cancer.

Impact of cytotoxic chemotherapy on PD-L1 expression in patients with non-small cell lung cancer negative for EGFR mutation and ALK fusion.

Kaoru Tanaka, K. Nishio, K. Nakagawa, 2019, Lung cancer.

Fluorescence in situ hybridization analysis of chromosomal aberrations in mouse splenocytes at one- and two-months after total body exposure to iron-56 (Fe) ion particles or X-rays.

Kaoru Tanaka, M. Nenoi, Cuihua Liu, 2022, Mutation research. Genetic toxicology and environmental mutagenesis.

AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation.

Bing Wang, Shin Aoki, Akiko Sawa, 2014, Biochemical and biophysical research communications.

Association of Immune-Related Adverse Events With Nivolumab Efficacy in Non–Small-Cell Lung Cancer

Kaoru Tanaka, Y. Hasegawa, K. Nakagawa, 2017, JAMA oncology.

Phase I trial of OTS11101, an anti‐angiogenic vaccine targeting vascular endothelial growth factor receptor 1 in solid tumor

Kaoru Tanaka, K. Nishio, T. Satoh, 2013, Cancer science.

Docetaxel plus cisplatin in recurrent and/or metastatic non-squamous-cell head and neck cancer: a multicenter phase II trial

Kaoru Tanaka, K. Nishio, K. Sakai, 2021, Medical Oncology.

Peritumoural ground-glass opacity associated with tumour pseudoprogression in a patient with non-small cell lung cancer treated with nivolumab

Kaoru Tanaka, J. Tanizaki, K. Nakagawa, 2017, ESMO Open.

Cystic brain metastasis in non-small-cell lung cancer with ALK rearrangement.

Y. Nishimura, A. Kato, Kaoru Tanaka, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70.

K. Hirokawa, Kaoru Tanaka, M. Kitagawa, 2005, Leukemia research.

Friend Leukemia Virus Infection Enhances DNA Damage-Induced Apoptosis of Hematopoietic Cells, Causing Lethal Anemia in C3H Hosts

K. Hirokawa, Kaoru Tanaka, M. Kitagawa, 2002, Journal of Virology.

Research and Development of Radioprotective Agents: A Mini-Review

B. Wang, Kaoru Tanaka, Yi Xie, 2017 .

A randomized phase 3 study of maintenance therapy with S‐1 plus best supportive care versus best supportive care after induction therapy with carboplatin plus S‐1 for advanced or relapsed squamous cell carcinoma of the lung (WJOG7512L)

M. Ando, Kaoru Tanaka, Y. Nakanishi, 2020, Cancer.

Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma

Y. Nishimura, Kaoru Tanaka, K. Nishio, 2013, Cancer medicine.

EGFR mutation up-regulates EGR1 expression through the ERK pathway.

Kaoru Tanaka, H. Yokote, K. Nishio, 2009, Anticancer research.

Gastroparesis as a significant gastrointestinal adverse event during intensive chemotherapy for solid caner: a case report

Kaoru Tanaka, K. Nakagawa, K. Haratani, 2021, Translational cancer research.

CAPP-seq analysis of circulating tumor DNA from patients with EGFR T790M–positive lung cancer after osimertinib

Kaoru Tanaka, K. Nishio, J. Tanizaki, 2021, International Journal of Clinical Oncology.

Total body 100-mGy X-irradiation does not induce Alzheimer's disease-like pathogenesis or memory impairment in mice

B. Wang, T. Ono, T. Suhara, 2013, Journal of radiation research.

Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study)

Kaoru Tanaka, K. Nishio, H. Matsuoka, 2022, The oncologist.

Low‐dose total‐body carbon‐ion irradiations induce early transcriptional alteration without late Alzheimer's disease‐like pathogenesis and memory impairment in mice

B. Wang, T. Suhara, Kaoru Tanaka, 2014, Journal of neuroscience research.

Association of tumour burden with the efficacy of programmed cell death-1/programmed cell death ligand-1 inhibitors for treatment-naïve advanced non-small-cell lung cancer.

Kaoru Tanaka, K. Nishio, Y. Hasegawa, 2021, European journal of cancer.

First-line pembrolizumab ± chemotherapy for recurrent/metastatic head and neck cancer: Japanese subgroup of KEYNOTE-048

Kaoru Tanaka, T. Yoshizaki, K. Shiga, 2022, International Journal of Clinical Oncology.

Epidermal growth factor receptor lacking C‐terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

Kaoru Tanaka, H. Yokote, K. Nishio, 2009, Cancer science.

Antitumor Activity of BIBF 1120, a Triple Angiokinase Inhibitor, and Use of VEGFR2+pTyr+ Peripheral Blood Leukocytes as a Pharmacodynamic Biomarker In Vivo

M. Kudo, N. Saijo, Kaoru Tanaka, 2010, Clinical Cancer Research.

A comparative study of curated contents by knowledge-based curation system in cancer clinical sequencing

Shinichiro Suzuki, Shigeki Shimizu, Kazuko Sakai, 2019, Scientific Reports.

Clinical Application of the FoundationOne CDx Assay to Therapeutic Decision‐Making for Patients with Advanced Solid Tumors

T. Mitsudomi, H. Handa, Kaoru Tanaka, 2020, The oncologist.

Phase II/III trial of post-operative chemoradiotherapy comparing 3-weekly cisplatin with weekly cisplatin in high-risk patients with squamous cell carcinoma of head and neck (JCOG1008).

Kaoru Tanaka, T. Ogawa, N. Hanai, 2020 .

Progression-free and overall survival in patients with ALK rearrangement – positive non – small cell lung cancer treated sequentially with crizotinib and alectinib

Kaoru Tanaka, Y. Hasegawa, K. Okamoto, 2016 .

Correlative study of EGFR mutations or protein expressions of EGFR, phosphorylated EGFR, HER2, phosphorylated HER2 and IGFR-1 with gefitinib sensitivity in patients with non-small cell lung cancer: Results of West Japan Thoracic Oncology Group trial (WJTO)

M. Fukuoka, K. Tamura, A. Kubo, 2007 .

Phase 2 study of S‐1 and carboplatin plus bevacizumab followed by maintenance S‐1 and bevacizumab for chemotherapy‐naive patients with advanced nonsquamous non–small cell lung cancer

M. Satouchi, Kaoru Tanaka, S. Morita, 2013, Cancer.

X-ray-induced radioresistance against high-LET radiations from accelerated neon-ion beams in mice.

W. Bing, Kaoru Tanaka, M. Nenoi, 2012 .

Relieved residual damage in the hematopoietic system of mice rescued by radiation-induced adaptive response (Yonezawa Effect)

B. Wang, Kaoru Tanaka, M. Nenoi, 2012, Journal of radiation research.

Protective Effects of p53 Regulatory Agents Against High-LET Radiation-Induced Injury in Mice

Shintaro Ochi, Y. Nishiyama, A. Morita, 2020, Frontiers in Public Health.

Progression-Free and Overall Survival of Patients With ALK Rearrangement-Positive Non-Small Cell Lung Cancer Treated Sequentially With Crizotinib and Alectinib.

Kaoru Tanaka, Y. Hasegawa, K. Okamoto, 2016, Clinical lung cancer.

Mouse intestinal Lgr5+ stem cells are more sensitive to heavy ion irradiation than Bmi1+ stem cells.

B. Wang, Kaoru Tanaka, Guangming Zhou, 2019, Acta biochimica et biophysica Sinica.

Tumor immune microenvironment and nivolumab efficacy in EGFR mutation-positive non-small-cell lung cancer based on T790M status after disease progression during EGFR-TKI treatment

T. Mitsudomi, S. Tomida, Kaoru Tanaka, 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

Kaoru Tanaka, K. Nishio, I. Okamoto, 2012, Clinical Cancer Research.

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse.

B. Wang, Kaoru Tanaka, Y. Akasaka, 2012, Immunology Letters.

Recovery of brain dysfunction after methylmercury exposure in rats

S. Tobimatsu, Y. Goto, Kaoru Tanaka, 2000, Journal of the Neurological Sciences.

Effect of a Bonito Bouillon Extract on Food Intake and Fat Accumulation in Rats

Kaoru Tanaka, S. Kasaoka, S. Nakajima, 2008 .

Sodium orthovanadate inhibits p53-mediated apoptosis.

Y. Hosoi, Y. Matsumoto, A. Enomoto, 2010, Cancer research.

Clinical response to crizotinib retreatment after acquisition of drug resistance.

Kaoru Tanaka, H. Matsuoka, I. Okamoto, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.