A. Enders

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Comparison of predicted and actual consequences of missense mutations

T. Andrews, M. Field, B. Beutler, 2015, Proceedings of the National Academy of Sciences.

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

M. Field, T. Andrews, P. Humburg, 2016, Nature Communications.

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models

T. Andrews, M. Field, B. Beutler, 2012, Open Biology.

Phospho-tuning immunity through Denisovan, modern human and mouse TNFAIP3 gene variants

Benjamin T. Porebski, G. Nolan, M. Cox, 2019, bioRxiv.

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

S. Tangye, J. Cyster, B. Whittle, 2009, Nature Immunology.

Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets.

A. Bröer, S. Bröer, A. Enders, 2019, Blood advances.

Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects.

Anne-Kathrin Kienzler, L. Miosge, A. Enders, 2013, The Journal of allergy and clinical immunology.

Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells

A. Strasser, P. Bouillet, A. Enders, 2003, The Journal of experimental medicine.

Mice Deficient in the Putative Phospholipid Flippase ATP11C Exhibit Altered Erythrocyte Shape, Anemia, and Reduced Erythrocyte Life Span*♦

K. Kirk, S. Bröer, A. Enders, 2014, The Journal of Biological Chemistry.

German Society for Immunology and Australasian Society for Immunology joint Workshop 3rd–4th December 2015 – Meeting report

S. Heinzel, A. Enders, C. Kurts, 2016, European journal of immunology.

Immunodeficiency Signaling: Implications for Human Virus Control in Mice with Attenuated Tcr T Cell Expansion Is the Limiting Factor Of

H. Pircher, S. Ehl, A. Enders, 2022 .

T Cell Expansion Is the Limiting Factor of Virus Control in Mice with Attenuated TCR Signaling: Implications for Human Immunodeficiency

H. Pircher, S. Ehl, A. Enders, 2015, The Journal of Immunology.

Reduced memory B cells in patients with hyper IgE syndrome.

A. Plebani, J. Franco, J. Litzman, 2008, Clinical immunology.

Gray platelet syndrome can mimic autoimmune lymphoproliferative syndrome.

U. Pannicke, K. Schwarz, F. Rieux-Laucat, 2015, Blood.

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

I. Konstantinov, Y. D'udekem, L. Loh, 2016, Nature Immunology.

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

J. McCluskey, J. Rossjohn, D. Pellicci, 2015, The Journal of experimental medicine.

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.

K. Schwarz, S. Ehl, A. Enders, 2011, Blood.

Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids

V. V. Ganusov, L. Miosge, Y. Sontani, 2017, Science Immunology.

Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II.

U. Pannicke, K. Schwarz, S. Ehl, 2006, Blood.

ZBTB7B (Th-POK) Regulates the Development of IL-17–Producing CD1d-Restricted Mouse NKT Cells

A. Enders, C. Goodnow, M. Yabas, 2012, The Journal of Immunology.

Two siblings with lethal pneumococcal meningitis in a family with a mutation in Interleukin-1 receptor-associated kinase 4.

U. Pannicke, K. Schwarz, S. Ehl, 2004, The Journal of pediatrics.

DOCK8 is critical for the survival and function of NKT cells.

Joanne M. Smart, S. Tangye, H. Lockstone, 2013, Blood.

ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production

S. Bröer, A. Enders, M. Yabas, 2017, Front. Immunol..

Thymic precursors to the mucosal-associated invariant T cell lineage

I. Konstantinov, Y. D'udekem, L. Loh, 2016 .

Development of granulomatous common variable immunodeficiency subsequent to infection with Toxoplasma gondii

A. Marx, S. Mrusek, S. Ehl, 2004, Clinical and experimental immunology.

Gut microbiome-depleting antibiotic regimens are not tolerated by all mouse strains: learn from (our) bitter experience

A. Enders, T. Neeman, A. Fahrer, 2022, Journal for immunotherapy of cancer.

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

Ivan K. Chinn, J. Lupski, U. Pannicke, 2019, The Journal of allergy and clinical immunology.

Corrigendum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

S. Tangye, J. Cyster, B. Whittle, 2010, Nature Immunology.

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

J. Pettitt, A. Enders, A. Brüstle, 2022, Nature Communications.

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Benjamin T. Porebski, G. Nolan, M. Cox, 2019, Nature Immunology.

T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency

A. Enders, C. Goodnow, S. Daley, 2010, Proceedings of the National Academy of Sciences.

Identical phenotype in patients with somatic and germline CD95 mutations requires a new diagnostic approach to autoimmune lymphoproliferative syndrome.

S. Ehl, A. Enders, C. Niemeyer, 2005, The Journal of pediatrics.

The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

Yan Mei, T. Andrews, V. Cho, 2014, Genome Biology.

Unravelling the association of partial T-cell immunodeficiency and immune dysregulation

A. Liston, A. Enders, O. Siggs, 2008, Nature Reviews Immunology.

Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency.

U. Pannicke, K. Schwarz, S. Ehl, 2015, Blood.

A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice

T. Andrews, S. Rosenzweig, L. Miosge, 2021, The Journal of Immunology.

T-bet–dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow

J. Chun, L. Lanier, S. Watson, 2009, The Journal of experimental medicine.

Dysregulation of PAX5 causes uncommitted B cell development and tumorigenesis in mice

T. Andrews, E. Eyras, S. Nutt, 2021, bioRxiv.

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

T. Andrews, M. Field, J. Cyster, 2013, eLife.

Loss of hnRNPLL‐dependent splicing of Ptprc has no impact on B‐cell development, activation and terminal differentiation into antibody‐secreting cells

A. Enders, C. Goodnow, G. Hoyne, 2020, Immunology and cell biology.

Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes

T. Andrews, M. Field, L. Miosge, 2014, Proceedings of the National Academy of Sciences.

A variant of SCID with specific immune responses and predominance of γδ T cells

U. Pannicke, K. Schwarz, F. Mascart, 2005 .

A Severe Form of Human Combined Immunodeficiency Due to Mutations in DNA Ligase IV1

U. Pannicke, K. Schwarz, W. Friedrich, 2006, The Journal of Immunology.

Influence of a Single Viral Epitope on T Cell Response and Disease After Infection of Mice with Respiratory Syncytial Virus1

S. Mrusek, S. Ehl, A. Enders, 2007, The Journal of Immunology.

A variant of SCID with specific immune responses and predominance of gamma delta T cells.

U. Pannicke, K. Schwarz, F. Mascart, 2005, The Journal of clinical investigation.

Mouse strains with point mutations in TAP1 and TAP2

D. Tscharke, B. Whittle, A. Enders, 2010, Immunology and cell biology.

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency

U. Pannicke, K. Schwarz, J. Casanova, 2023, Science Immunology.

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

T. Andrews, V. Pascual, E. Stone, 2019, Nature Communications.

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8− dendritic cells require the intramembrane endopeptidase SPPL2A

T. Andrews, M. Field, A. Rimmer, 2013, The Journal of experimental medicine.

Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation

B. Beutler, A. Enders, K. Horikawa, 2013, Genes and Immunity.

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

J. Sprent, S. Bröer, Yafei Zhang, 2011, Nature Immunology.

Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak

U. Pannicke, K. Schwarz, S. Ehl, 2016 .

syndrome type II Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak

U. Pannicke, K. Schwarz, A. Yoshimi, 2013 .

The molecular basis for the development of adult T‐cell leukemia/lymphoma in patients with an IRF4K59R mutation

A. Enders, M. Casarotto, Simon J. Williams, 2021, Protein science : a publication of the Protein Society.

Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations

Steve D. M. Brown, Ann-Marie Mallon, Gerton Lunter, 2013, PLoS genetics.

Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion

D. Tscharke, L. Miosge, Y. Sontani, 2017, Proceedings of the National Academy of Sciences.

Atp11c Is Critical for Phosphatidylserine Internalization and B Lymphocyte Differentiation Hhs Public Access Sequencing and Mutation Identification Generation of Bone Marrow Chimeras Annexin-v Staining Supplementary Material

J. Sprent, S. Bröer, Yafei Zhang, 2022 .

Epistatic interactions between mutations of TACI (TNFRSF13B) and TCF3 result in a severe primary immunodeficiency disorder and systemic lupus erythematosus

P. Hodgkin, A. Enders, P. Browett, 2017, Clinical & translational immunology.

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

J. Pettitt, A. Enders, A. Brüstle, 2022, Nature Communications.

ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes

S. Bröer, A. Enders, M. Yabas, 2016, PloS one.

Reducing the search space for causal genetic variants with VASP

T. Daniel Andrews, Carola G. Vinuesa, Matthew C. Cook, 2015, Bioinform..

Structural determinants of the IRF4/DNA homodimeric complex

A. Enders, M. Casarotto, Simon J. Williams, 2021, Nucleic acids research.

Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre‐excitation syndrome

U. Pannicke, K. Schwarz, M. Ballmaier, 2020, European journal of immunology.

DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infection

D. Tscharke, I. Flesch, L. Miosge, 2023, bioRxiv.

Finding new immune regulatory genes by ENU mutagenesis

T. Andrews, L. Miosge, Y. Sontani, 2012, Journal of Translational Medicine.

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

T. Andrews, V. Pascual, M. Field, 2019, Nature Communications.

ATP11c is critical for phosphatidylserine internalization and B lymphocyte differentiation

J. Sprent, S. Bröer, Yafei Zhang, 2011, Nature immunology.

Zeb2 drives the formation of CD11c+ atypical B cells to sustain germinal centers that control persistent infection

J. Zaunders, A. Enders, I. Cockburn, 2024, Science Immunology.

IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

A. Enders, R. Chand, Bahar Miraghazadeh, 2024, Nature communications.