H. Freake

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Zinc Status Alters Growth and Oxidative Stress Responses in Rat Hepatoma Cells

K. Sankavaram, Leelyn Chong, R. Bruno, 2014, Nutrition and cancer.

Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism

H. Freake, M. Fernández, Amrita Dutta, 2006, Lipids in Health and Disease.

Metabolomics in the opening decade of the 21st century: building the roads to individualized health.

D E Bauman, D. Burrin, J. Milner, 2004, The Journal of nutrition.

The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase.

H. Freake, M. Fernández, I. Lofgren, 2005, The Journal of nutrition.

Regulation of brown adipose tissue lipogenesis by thyroid hormone and the sympathetic nervous system.

H. Freake, P. Leahy, W. Yeh, 1993, The American journal of physiology.

Stimulation of S14 mRNA and lipogenesis in brown fat by hypothyroidism, cold exposure, and cafeteria feeding: evidence supporting a general role for S14 in lipogenesis and lipogenesis in the maintenance of thermogenesis.

H. Freake, J. Oppenheimer, 1987, Proceedings of the National Academy of Sciences of the United States of America.

A combination of psyllium and plant sterols alters lipoprotein metabolism in hypercholesterolemic subjects by modifying the intravascular processing of lipoproteins and increasing LDL uptake.

H. Freake, M. Fernández, J. Volek, 2007, The Journal of nutrition.

Advances in our understanding of thyroid hormone action at the cellular level.

N. Wong, H. Freake, C. Mariash, 1987, Endocrine reviews.

Acute energy deprivation affects skeletal muscle protein synthesis and associated intracellular signaling proteins in physically active adults.

R. Wolfe, H. Freake, S. Pasiakos, 2010, The Journal of nutrition.

Tissue-specific regulation of fatty acid synthesis by thyroid hormone.

H. Freake, Y. Moon, B. Blennemann, 1992, Endocrinology.

Tissue-specific regulation of lipogenic mRNAs by thyroid hormone

H. Freake, P. Leahy, B. Blennemann, 1995, Molecular and Cellular Endocrinology.

Illuminating zinc in biological systems.

H. Freake, C. Brückner, Nathaniel C. Lim, 2004, Chemistry.

Illuminating Zinc in Biological Systems

H. Freake, C. Brueckner, Nathaniel C. Lim, 2006 .

Glucose Regulation of the Acetyl-CoA Carboxylase Promoter PI in Rat Hepatocytes*

S. Koo, H. Freake, H. Towle, 2001, The Journal of Biological Chemistry.

Carbohydrate restriction alters hepatic cholesterol metabolism in guinea pigs fed a hypercholesterolemic diet.

H. Freake, M. Fernández, J. Volek, 2007, The Journal of nutrition.

Gender and hormonal status affect the regulation of hepatic cholesterol 7alpha-hydroxylase activity and mRNA abundance by dietary soluble fiber in the guinea pig.

H. Freake, M. Fernández, Suheeta Roy, 2002, Atherosclerosis.

Corn fiber oil lowers plasma cholesterol by altering hepatic cholesterol metabolism and up-regulating LDL receptors in guinea pigs.

H. Freake, M. Fernández, Suheeta Roy, 2002, The Journal of nutrition.

Triiodothyronine nuclear binding capacity in rat tissues correlates with a 6.0 kilobase (kb) and not a 2.6 kb messenger ribonucleic acid hybridization signal generated by a human c-erbA probe.

H. Freake, J. Oppenheimer, H. Schwartz, 1988, Molecular endocrinology.

1,25-dihydroxyvitamin D3 specifically binds to a human breast cancer cell line (T47D) and stimulates growth.

C. Marcocci, H. Freake, I. Macintyre, 1981, Biochemical and biophysical research communications.

Sex and hormonal status modulate the effects of psyllium on plasma lipids and monocyte gene expression in humans.

H. Freake, S. Vega-López, M. Fernández, 2003, The Journal of nutrition.

Hormones and nutrients regulate acetyl-CoA carboxylase promoter I in rat primary hepatocytes.

H. Freake, Mak-Soon Lee, Yangha Kim, 2005, Journal of nutritional science and vitaminology.

Changes in surface antigens of HL-60 cells during differentiation in vitro

D. Catovsky, H. Zola, H. Freake, 1984, Blut.

The effect of vitamin D3 metabolites on normal and leukemic bone marrow cells in vitro.

D. Catovsky, H. Freake, J. Goldman, 1984, International journal of cell cloning.

Atorvastatin and simvastatin have distinct effects on hydroxy methylglutaryl-CoA reductase activity and mRNA abundance in the guinea pig

H. Freake, M. Fernandez, M. Fernández, 1999, Lipids.

Coumarin-based chemosensors for zinc(II): toward the determination of the design algorithm for CHEF-type and ratiometric probes.

H. Freake, C. Brückner, M. Tanudra, 2005, Inorganic chemistry.

Specific uptake of 1,25-dihydroxycholecalciferol by human chronic myeloid leukemia cells.

H. Freake, D. Mccarthy, J. Iwasaki, 1984, Cancer research.

The Effects of Transformation and ZnT‐1 Silencing on Zinc Homeostasis in Cultured Cells

K. Sankavaram, H. Freake, 2010, The Journal of nutritional biochemistry.

Thyroid hormone regulates the acetyl-CoA carboxylase PI promoter.

H. Freake, C. Huang, 1998, Biochemical and biophysical research communications.

Uncoupling proteins: beyond brown adipose tissue.

H. Freake, 2009, Nutrition reviews.

Specific binding of 1,25 dihydroxyvitamin D3 in the VX2 carcinoma.

J. Eisman, T. Martin, H. Freake, 1980, Biochemical and biophysical research communications.

The regulation of lipogenesis by thyroid hormone and its contribution to thermogenesis.

H. Freake, J. Oppenheimer, H. Schwartz, 1989, Endocrinology.

Interaction of Thyroid Hormone and Carbohydrates on Hepatic Gene Expression

H. Freake, C. Mariash, W. Kinlaw, 1987 .

Specific binding of 1,25 dihydroxyvitamin D3 in lymphocytes.

H. Freake, I. Macintyre, R. M. Walter, 1984, Metabolism: clinical and experimental.

Differences in antibody recognition of the triiodothyronine nuclear receptor and c-erbA products.

H. Freake, J. Ghysdael, Y. Goldberg, 1988, Molecular endocrinology.

Green tea catechin enhances cholesterol 7α-hydroxylase gene expression in HepG2 cells

H. Freake, Mak-Soon Lee, Yangha Kim, 2008, British Journal of Nutrition.

Hormonal and nutritional regulation of lipogenic enzyme mRNA levels in rat primary white and brown adipocytes.

H. Freake, Y. Moon, 2003, Journal of nutritional science and vitaminology.

Growth inhibition of human breast cancer cells induced by calcitonin.

H. Freake, J. Iwasaki, Y. Iwasaki, 1983, Biochemical and biophysical research communications.

1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukaemia (HL60) cells and induces monocyte-macrophage differentiation in HL60 and normal human bone marrow cells.

H Zola, D. Catovsky, H. Zola, 1983, Leukemia research.

Actions and interactions of thyroid hormone and zinc status in growing rats.

H. Freake, S. Zinn, K. Govoni, 2001, The Journal of nutrition.

The regulation of LIV‐1 mRNA in MDA‐MB‐231 human breast cancer cells and its association with E‐cadherin

K. Sankavaram, Leelyn Chong, H. Freake, 2010 .

Synthesis of a fluorescent chemosensor suitable for the imaging of zinc(II) in live cells.

H. Freake, C. Brückner, Nathaniel C. Lim, 2003, Bioorganic & medicinal chemistry letters.

Zinc and Cancer: Implications for LIV-1 in Breast Cancer

H. Freake, Bruce J. Grattan, 2012, Nutrients.

A genetic mutation in PPAR gamma is associated with enhanced fat cell differentiation: implications for human obesity.

H. Freake, 2009, Nutrition reviews.

Thermogenesis and thyroid function.

H. Freake, J. Oppenheimer, 1995, Annual review of nutrition.

Demonstration and organ distribution of the 1,25-dihydroxyvitamin D3-binding protein in fish (A. anguilla).

C. Marcocci, H. Freake, I. Macintyre, 1982, Endocrinology.

High carbohydrate diet and starvation regulate lipogenic mRNA in rats in a tissue-specific manner.

H. Freake, T. S. Kim, 1996, The Journal of nutrition.

Promoter usage determines tissue specific responsiveness of the rat acetyl-CoA carboxylase gene.

H. Freake, P. Leahy, T. S. Kim, 1996, Biochemical and biophysical research communications.

Measurement of 1,25-dihydroxyvitamin D3 receptors in breast cancer and their relationship to biochemical and clinical indices.

D. Easton, R. Coombes, C. Marcocci, 1984, Cancer research.

1,25(OH)2D3 causes monocytic differentiation of normal human bone marrow in vitro

D. Catovsky, H. Zola, H. Freake, 1983 .

Molecular biological approaches to studying trace minerals: why should clinicians care?

H. Freake, 1993, Journal of the American College of Nutrition.

Zinc: Physiology, Dietary Sources, and Requirements

K. Sankavaram, H. Freake, 2013 .

Chelation of zinc amplifies induction of growth hormone mRNA levels in cultured rat pituitary tumor cells.

H. Freake, S. Chattopadhyay, M. Sciaudone, 2000, The Journal of nutrition.

The nutritional phenotype in the age of metabolomics.

D E Bauman, D. Burrin, J. Milner, 2005, The Journal of nutrition.

Rapid homeostatic response of H4IIE cells to diethylenetriaminepentaacetic acid is not due to changes in the amount or localization of ZnT-1 protein.

K. Sankavaram, Leelyn Chong, H. Freake, 2011, Nutrition research.

Tissue specific regulation of lipogenesis by carbohydrate feeding and twenty four hour starvation in the rat

H. Freake, Tae-Suk Kim, 1993 .

Zinc chelation enhances thyroid hormone induction of growth hormone mRNA in GH3 cells

H. Freake, S. Chattopadhyay, 1998, Molecular and Cellular Endocrinology.

Evaluation of STRONG-CT: A Program Supporting Minority and First-Generation U.S. Science Students.

Timothy J Bauerle, Alyssa K. McGonagle, H. Freake, 2014 .

Zinc retention differs between primary and transformed cells in response to zinc deprivation.

K. Sankavaram, H. Freake, A. Franco, 2010, Journal of Nutritional Biochemistry.

Diethylenetriaminepentaacetic acid enhances thyroid hormone action by a transcriptional mechanism

H. Freake, S. Zinn, M. Schaller, 2007, Biological Trace Element Research.

Nutrition: a reservoir for integrative science.

L. Allen, J. King, M. Failla, 2001, The Journal of nutrition.

Specific binding of 1,25-dihydroxycholecalciferol in human medullary thyroid carcinoma.

H. Freake, I. Macintyre, 1982, The Biochemical journal.

Effect of thyroid hormones and high carbohydrate feeding on gene expression in rat epididymal adipose tissue.

H. Freake, C. Mariash, J. Oppenheimer, 1987, Endocrinology.

Social research in an integrated science of nutrition: future directions.

H. Freake, G. Pelto, 2003, The Journal of nutrition.

Stereospecific transport of triidothyronine to cytoplasm and nucleus in GH1 cells

H. Freake, A. Mooradian, J. Oppenheimer, 1986, Molecular and Cellular Endocrinology.