Xinbin Chen

发表

Mutant p53 Cooperates with Knockdown of Endogenous Wild-Type p53 to Disrupt Tubulogenesis in Madin-Darby Canine Kidney Cells

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2013, PloS one.

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

Xinbin Chen, A. Willis, E. Jung, 2004, Oncogene.

Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis

Michael Dohn, Xinbin Chen, M. Dohn, 2001, Oncogene.

Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity.

K. Harms, Xinbin Chen, Xinbin Chen, 2007, Cancer research.

Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53

Jian Wang, Jiang Shou, Xinbin Chen, 2000, Oncogene.

Targeted repression of bone morphogenetic protein 7, a novel target of the p53 family, triggers proliferative defect in p53-deficient breast cancer cells.

Wensheng Yan, Xinbin Chen, Wensheng Yan, 2007, Cancer research.

Regulation of the p53 transcriptional activity

Xinbin Chen, Gang Liu, 2006, Journal of cellular biochemistry.

A ROLE FOR P 63 IN THE REGULATION OF CELL CYCLE PROGRESSION AND CELL DEATH by

Xinbin Chen, D. Crawford, J. Ruppert, 2007 .

Fluoroquinolone-Mediated Inhibition of Cell Growth, S-G2/M Cell Cycle Arrest, and Apoptosis in Canine Osteosarcoma Cell Lines

Xinbin Chen, K. Seo, R. Holt, 2012, PloS one.

Examination of the expanding pathways for the regulation of p21 expression and activity.

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2010, Cellular signalling.

Cancer The 'RBP'eutics - RNA-Binding Proteins as Therapeutic Targets for Cancer.

Xinbin Chen, Shakur Mohibi, Jin Zhang, 2019, Pharmacology & therapeutics.

The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63.

Xinbin Chen, E. Helton, Jian-hui Zhu, 2006, The Journal of biological chemistry.

TAp73 Protein Stability Is Controlled by Histone Deacetylase 1 via Regulation of Hsp90 Chaperone Function*

Xinbin Chen, Jin Zhang, Enshun Xu, 2013, The Journal of Biological Chemistry.

ΔNp63, a Target of DEC1 and Histone Deacetylase 2, Modulates the Efficacy of Histone Deacetylase Inhibitors in Growth Suppression and Keratinocyte Differentiation*

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2011, The Journal of Biological Chemistry.

TAp63γ and ΔNp63γ are regulated by RBM38 via mRNA stability and have an opposing function in growth suppression

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2017, Oncotarget.

Arsenic Suppresses Cell Survival via Pirh2-mediated Proteasomal Degradation of ΔNp63 Protein*

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2012, The Journal of Biological Chemistry.

Clusterin, a Novel DEC1 Target, Modulates DNA Damage–Mediated Cell Death

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2018, Molecular Cancer Research.

DEC1 Coordinates with HDAC8 to Differentially Regulate TAp73 and ΔNp73 Expression

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2014, PloS one.

RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability

Xinbin Chen, Jin Zhang, Seong Jun Cho, 2010, Proceedings of the National Academy of Sciences.

Myocardial Smad4 Is Essential for Cardiogenesis in Mouse Embryos

C. Deng, Wensheng Yan, Xinbin Chen, 2007, Circulation research.

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

K. Lam, O. Fiehn, A. Borowsky, 2019, Nature Communications.

MDM 2 Is a Negative Regulator of p 21 WAF 1 / CIP 1 , Independent of p 53 *

Xinbin Chen, Hui Wang, S. Agrawal, 2004 .

Advances in Brief p 53 , through p 21 ( WAF 1 / CIP 1 ) , Induces Cyclin Dl Synthesis 1

J. Bargonetti, C. Prives, Xinbin Chen, 2006 .

TITLE : Functions of Wild-type and Mutant Forms of p 53 in Breast Cancer PRINCIPAL INVESTIGATOR ( S ) : Doctor

Xinbin Chen, 2022 .

Cyclin G: a regulator of the p53-Mdm2 network.

Xinbin Chen, 2002, Developmental cell.

The Rbm38-p63 Feedback Loop Is Critical for Tumor Suppression and Longevity

Xinbin Chen, E. Flores, Mingyi Chen, 2018, Oncogene.

P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition

Yanhong Zhang, Xinbin Chen, Jin Zhang, 2015, Oncotarget.

FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression

Yanhong Zhang, Xinbin Chen, Mingyi Chen, 2020, The Journal of pathology.

Mice Deficient in the RNA-Binding Protein Zfp871 Are Prone to Early Death and Steatohepatitis in Part through the p53–Mdm2 Axis

Xinbin Chen, Mingyi Chen, Shakur Mohibi, 2021, Molecular Cancer Research.

Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2016, Genes & development.

Arsenic Trioxide Reactivates Proteasome-Dependent Degradation of Mutant p53 Protein in Cancer Cells in Part via Enhanced Expression of Pirh2 E3 Ligase

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2014, PloS one.

Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38

Yanhong Zhang, Xinbin Chen, Mingyi Chen, 2021, Genes & development.

PABPN1, a target of p63, modulates keratinocyte differentiation through regulation of p63α mRNA translation.

Xinbin Chen, Shakur Mohibi, Jin Zhang, 2020, The Journal of investigative dermatology.

Chromatin , Gene , and RNA Regulation RNA-Binding Protein RBM 24 Regulates p 63 Expression via mRNA Stability

Seong-Jun Cho, Xinbin Chen, Jin Zhang, 2014 .

RNA-Binding Protein RBM24 Regulates p63 Expression via mRNA Stability

Seong-Jun Cho, Xinbin Chen, Jin Zhang, 2013, Molecular Cancer Research.

Pirh2 E3 Ubiquitin Ligase Modulates Keratinocyte Differentiation Through p63

Wensheng Yan, Xinbin Chen, Yong-Sam Jung, 2012, The Journal of investigative dermatology.

Poly (C)-Binding Protein 1 Regulates p63 Expression through mRNA Stability

Seong-Jun Cho, Xinbin Chen, Yong-Sam Jung, 2013, PloS one.

Iron Regulatory Protein 2 Exerts its Oncogenic Activities by Suppressing TAp63 Expression

Yanhong Zhang, Xinbin Chen, Xiuli Feng, 2020, Molecular Cancer Research.

Optimization of eIF4E-Binding Peptide Pep8 to Disrupt the RBM38-eIF4E Complex for Induction of p53 and Tumor Suppression

Xinbin Chen, C. Lucchesi, Jin Zhang, 2022, Frontiers in Oncology.

Isoform-specific disruption of the TP73 gene reveals a critical role for TAp73γ in tumorigenesis via leptin

Wensheng Yan, Xinbin Chen, Mingyi Chen, 2022, bioRxiv.

Rbm24, a target of p53, is necessary for proper expression of p53 and heart development

Yanhong Zhang, Xinbin Chen, Shakur Mohibi, 2018, Cell Death & Differentiation.

A new function for p53 tetramerization domain in cell fate control

Xinbin Chen, C. Lucchesi, Jin Zhang, 2016, Cell cycle.

Pirh2 E3 Ubiquitin Ligase Targets DNA Polymerase Eta for 20S Proteasomal Degradation

Xinbin Chen, Gang Liu, Yong-Sam Jung, 2009, Molecular and Cellular Biology.

DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation.

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2012, DNA repair.

p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1

Wensheng Yan, Xinbin Chen, Mingyi Chen, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Mdm2 is a target and mediator of IRP2 in cell growth control

Yanhong Zhang, Xinbin Chen, Jin Zhang, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Serine 123 Phosphorylation Modulates p21 Protein Stability and Activity by Suppressing Ubiquitin-independent Proteasomal Degradation*

M. Zhang, Wensheng Yan, Xinbin Chen, 2012, The Journal of Biological Chemistry.

p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

O. Fiehn, Xinbin Chen, Shakur Mohibi, 2022, Cells.

ZFP14 Regulates Cancer Cell Growth and Migration by Modulating p53 Protein Stability as Part of the MDM2 E3 Ubiquitin Ligase Complex

Xinbin Chen, Shakur Mohibi, Jin Zhang, 2022, Cancers.

Poly zinc finger protein ZFP14 suppresses lymphomagenesis and abnormal inflammatory response via the HOXA gene cluster

Xinbin Chen, Mingyi Chen, Shakur Mohibi, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Myosin VI Is Differentially Regulated by DNA Damage in p53- and Cell Type-dependent Manners*

Seong-Jun Cho, Xinbin Chen, 2010, The Journal of Biological Chemistry.

The RNA-binding protein RBM24 regulates lipid metabolism and SLC7A11 mRNA stability to modulate ferroptosis and inflammatory response

Xinbin Chen, Mingyi Chen, Jin Zhang, 2022, Frontiers in Cell and Developmental Biology.

Microglia-Derived Olfactomedin-like 3 Is a Potent Angiogenic Factor in Primary Mouse Brain Endothelial Cells: A Novel Target for Glioblastoma

Xinbin Chen, F. Meyers, Ryan G. Toedebusch, 2022, International journal of molecular sciences.

Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells

Xinbin Chen, Ryan G. Toedebusch, C. Lucchesi, 2021, International journal of molecular sciences.

p63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

Xinbin Chen, M. Dohn, Shungzhen Zhang, 2001, Oncogene.

Effects of p21Cip1/Waf1 at Both the G1/S and the G2/M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

L. Hengst, S. Reed, C. Prives, 1998, Molecular and Cellular Biology.

RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript.

Wensheng Yan, Xinbin Chen, L. Shu, 2006, Genes & development.

p53 induces TAP1 and enhances the transport of MHC class I peptides

Xinbin Chen, Jieyuan Jiang, J. Shou, 1999, Oncogene.

DEC1, a Basic Helix-Loop-Helix Transcription Factor and a Novel Target Gene of the p53 Family, Mediates p53-dependent Premature Senescence*

Xinbin Chen, Y. Qian, B. Yan, 2008, Journal of Biological Chemistry.

MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth

Jun Luo, Yezi Zhu, Wei Lou, 2012, PloS one.

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy

H. Kung, Yanhong Zhang, Xinbin Chen, 2016, Cell Death and Differentiation.

DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability.

Seong-Jun Cho, Xinbin Chen, Yong-Sam Jung, 2014, The Biochemical journal.

The Lysine-specific Demethylase 1 Is Required for Cell Proliferation in Both p53-dependent and -independent Manners*

Xinbin Chen, A. Scoumanne, 2007, Journal of Biological Chemistry.

Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells.

R. Spang, J. Biegel, I. Artner, 2012, Cancer research.

Tumor and Stem Cell Biology De fi nition of Genetic Events Directing the Development of Distinct Types of Brain Tumors from Postnatal Neural Stem / Progenitor Cells

R. Spang, J. Biegel, I. Artner, 2012 .

Directing the Development of Distinct Types of Brain Tumors from Postnatal Neural Stem / Progenitor Cells

R. Spang, J. Biegel, I. Artner, 2012 .

SNF5, a core component of the Swi/Snf complex, is necessary for p53 expression and cell survival in part via eIF4E

Wensheng Yan, Xinbin Chen, Yang Xu, 2010, Oncogene.

Identification of GRO1 as a Critical Determinant for Mutant p53 Gain of Function*

Wensheng Yan, Xinbin Chen, 2009, Journal of Biological Chemistry.

MicroRNA let-7c Suppresses Androgen Receptor Expression and Activity via Regulation of Myc Expression in Prostate Cancer Cells*

H. Kung, Yezi Zhu, R. deVere White, 2011, The Journal of Biological Chemistry.

Tumor suppressor gene-inducible cell lines.

Xinbin Chen, A. Willis, M. Dohn, 2003, Methods in molecular biology.

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

K. Lloyd, Yanhong Zhang, Wensheng Yan, 2017, Genes & development.

Senescence regulation by the p53 protein family.

Xinbin Chen, Y. Qian, Yingjuan Qian, 2013, Methods in molecular biology.

Tumor suppression by p53: making cells senescent.

Xinbin Chen, Y. Qian, Yingjuan Qian, 2010, Histology and histopathology.

ID1, Inhibitor of Differentiation/DNA Binding, Is an Effector of the p53-dependent DNA Damage Response Pathway*

Xinbin Chen, Y. Qian, Yingjuan Qian, 2008, Journal of Biological Chemistry.

Mutant p53 Protein Is Targeted by Arsenic for Degradation and Plays a Role in Arsenic-mediated Growth Suppression*

Seong-Jun Cho, Yanhong Zhang, Wensheng Yan, 2011, The Journal of Biological Chemistry.

Modulation of the p53 family network by RNA-binding proteins.

Xinbin Chen, C. Lucchesi, Jin Zhang, 2016, Translational cancer research.

MDM2 Expression Is Repressed by The RNA-Binding Protein RNPC1 via mRNA Stability

Xinbin Chen, Jin Zhang, Enshun Xu, 2012, Oncogene.

Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway

Xinbin Chen, Mingyi Chen, Shakur Mohibi, 2022, Oncogene.

The p53 Family: A Role in Lipid and Iron Metabolism

Xinbin Chen, Jin Zhang, Kyra Laubach, 2021, Frontiers in Cell and Developmental Biology.

Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis

Yanhong Zhang, Xinbin Chen, Xiuli Feng, 2019, Oncogene.

p53 tumor suppressor and iron homeostasis

Xinbin Chen, Jin Zhang, 2018, The FEBS journal.

The p73 Tumor Suppressor Is Targeted by Pirh2 RING Finger E3 Ubiquitin Ligase for the Proteasome-dependent Degradation*

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2011, The Journal of Biological Chemistry.

Mitochondrial Uncoupling Inhibits p53 Mitochondrial Translocation in TPA-Challenged Skin Epidermal JB6 Cells

Fei Wang, Xinbin Chen, Xueqi Fu, 2010, PloS one.

p53 modulation of the DNA damage response

Xinbin Chen, E. Helton, 2007, Journal of cellular biochemistry.

Isolation and Characterization of Fourteen Novel Putative and Nine Known Target Genes of the p53 Family

Xinbin Chen, A. Willis, Gang Liu, 2003, Cancer biology & therapy.

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

Xinbin Chen, Gang Liu, 2002, Oncogene.

Erratum: Cooperative DNA binding of p53 with TFIID (TBP): A possible mechanism for transcriptional activation (Genes and Development 7 (1837- 1849))

C. Prives, Xinbin Chen, G. Farmer, 1993 .

Development and characterization of 5 canine B-cell lymphoma cell lines.

Wensheng Yan, Xinbin Chen, Changying Shi, 2012, Leukemia research.

Survivin Expression Is Differentially Regulated by a Selective Cross-talk between RBM38 and miRNAs let-7b or miR-203a

R. Nussinov, B. Ma, Xinbin Chen, 2021, Cancer Research.

PPM1D regulates p21 expression via dephoshporylation at serine 123

Min Zhang, Xinbin Chen, Ruibing Cao, 2015, Cell cycle.

Role of Pirh2 in Mediating the Regulation of p53 and c-Myc

P. Boutros, I. Jurisica, A. Mes-Masson, 2011, PLoS genetics.

Myosin VI Is a Mediator of the p53-Dependent Cell Survival Pathway

Xinbin Chen, E. Jung, Gang Liu, 2006, Molecular and Cellular Biology.

p53, a Target of Estrogen Receptor (ER) α, Modulates DNA Damage-induced Growth Suppression in ER-positive Breast Cancer Cells*

Xinbin Chen, Gang Liu, Y. Qian, 2012, The Journal of Biological Chemistry.

p53 Is Necessary for the Apoptotic Response Mediated by a Transient Increase of Ras Activity

Xinbin Chen, Peihong Ma, Chang‐Yan Chen, 2002, Molecular and Cellular Biology.

Histone Methyltransferase NSD2/MMSET Mediates Constitutive NF-κB Signaling for Cancer Cell Proliferation, Survival, and Tumor Growth via a Feed-Forward Loop

C. Tepper, Ping Yang, H. Kung, 2012, Molecular and Cellular Biology.

GPX2, a Direct Target of p63, Inhibits Oxidative Stress-induced Apoptosis in a p53-dependent Manner*

Wensheng Yan, Xinbin Chen, 2006, Journal of Biological Chemistry.

Pirh2 RING‐finger E3 ubiquitin ligase: Its role in tumorigenesis and cancer therapy

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2012, FEBS letters.

Pirh 2 RING-finger E 3 ubiquitin ligase : Its role in tumorigenesis and cancer therapy

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2012 .

Establishment of a Dog Model for the p53 Family Pathway and Identification of a Novel Isoform of p21 Cyclin-Dependent Kinase Inhibitor

Xinbin Chen, C. Rodriguez, M. Kent, 2009, Molecular Cancer Research.

Definition of the p53 Functional Domains Necessary for Inducing Apoptosis*

Xinbin Chen, Jieyuan Jiang, Jian-hui Zhu, 2000, The Journal of Biological Chemistry.

p73 Expression Is Regulated by RNPC1, a Target of the p53 Family, via mRNA Stability

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2012, Molecular and Cellular Biology.

The C-terminal Sterile α Motif and the Extreme C Terminus Regulate the Transcriptional Activity of the α Isoform of p73*

Xinbin Chen, Gang Liu, 2005, Journal of Biological Chemistry.

ΔNp73β Is Active in Transactivation and Growth Suppression

Xinbin Chen, Hui Xiao, Gang Liu, 2004, Molecular and Cellular Biology.

Characterization of p73 functional domains necessary for transactivation and growth suppression

Xinbin Chen, A. Willis, Gang Liu, 2003, Oncogene.

p73 cooperates with DNA damage agents to induce apoptosis in MCF7 cells in a p53-dependent manner

Xinbin Chen, Jieyuan Jiang, Jian Wang, 2001, Oncogene.

p73 is transcriptionally regulated by DNA damage, p53, and p73

Xinbin Chen, Jieyuan Jiang, Jian Wang, 2001, Oncogene.

p53 Transcription-Dependent and -Independent Regulation of Cerebellar Neural Precursor Cell Apoptosis

Xinbin Chen, K. Roth, B. Klocke, 2007, Journal of neuropathology and experimental neurology.

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

C. Prives, P. Friedlander, Xinbin Chen, 2002, Oncogene.

DNA Polymerase η, the Product of the Xeroderma Pigmentosum Variant Gene and a Target of p53, Modulates the DNA Damage Checkpoint and p53 Activation

Xinbin Chen, Gang Liu, 2006, Molecular and Cellular Biology.

Rbm24, an RNA-binding Protein and a Target of p53, Regulates p21 Expression via mRNA Stability*

Min Zhang, Xinbin Chen, Y. Qian, 2013, The Journal of Biological Chemistry.

Effects of p21Cip1/Waf1 at Both the G1/S and the G2/M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

L. Hengst, S. Reed, C. Prives, 1998, Molecular and Cellular Biology.

MDM2 Is a Negative Regulator of p21WAF1/CIP1, Independent of p53*

Xinbin Chen, Hui Wang, S. Agrawal, 2004, Journal of Biological Chemistry.

Identification of a Novel p53 Functional Domain That Is Necessary for Mediating Apoptosis*

Xinbin Chen, Jieyuan Jiang, J. Zhu, 1998, The Journal of Biological Chemistry.

Mammary Epithelial Cell Polarity Is Regulated Differentially by p73 Isoforms via Epithelial-to-mesenchymal Transition*

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2012, The Journal of Biological Chemistry.

Mutant p53 Disrupts MCF-10A Cell Polarity in Three-dimensional Culture via Epithelial-to-mesenchymal Transitions*

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2011, The Journal of Biological Chemistry.

p21B, a variant of p21Waf1/Cip1, is induced by the p53 family

Xinbin Chen, S. Nozell, 2002, Oncogene.

p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability

Min Zhang, Wensheng Yan, Xinbin Chen, 2016, Oncotarget.

Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1

Seong-Jun Cho, Xinbin Chen, Jin Zhang, 2013, Genes & development.

Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1

Xinbin Chen, Yong-Sam Jung, Y. Qian, 2012, Proceedings of the National Academy of Sciences.

The epithelial cell transforming sequence 2, a guanine nucleotide exchange factor for Rho GTPases, is repressed by p53 via protein methyltransferases and is required for G1-S transition.

Xinbin Chen, A. Scoumanne, 2006, Cancer research.

A PolH transcript with a short 3'UTR enhances PolH expression and mediates cisplatin resistance.

Wensheng Yan, Xinbin Chen, Jin Zhang, 2019, Cancer research.

HuR Is Necessary for Mammary Epithelial Cell Proliferation and Polarity at Least in Part via ΔNp63

Seong-Jun Cho, Yanhong Zhang, Wensheng Yan, 2012, PloS one.

The C Terminus of p53 Family Proteins Is a Cell Fate Determinant

K. Harms, Xinbin Chen, 2005, Molecular and Cellular Biology.

Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels.

Hui Wang, Xinbin Chen, Hui Wang, 2005, Cancer research.

MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M

Xinbin Chen, Jian-hui Zhu, Jian‐hui Zhu, 2000, Molecular and Cellular Biology.

MCG 10 , a Novel p 53 Target Gene That Encodes a KH Domain RNA-Binding Protein , Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G 2M

Xinbin Chen, Jian-hui Zhu, Jian‐hui Zhu, 2000 .

Structural basis for gene activation by p53 family members

K. Harms, Xinbin Chen, A. Scoumanne, 2005, Cancer biology & therapy.

Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors

R. Cardiff, Wensheng Yan, Xinbin Chen, 2014, Proceedings of the National Academy of Sciences.

Genetic Ablation of Rbm38 Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN.

Yanhong Zhang, Xinbin Chen, H. Yang, 2018, Cancer research.

Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality

Seong-Jun Cho, Wensheng Yan, Xinbin Chen, 2013, Proceedings of the National Academy of Sciences.

G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery.

Yanhong Zhang, Xinbin Chen, A. Scoumanne, 2010, Molecular and cellular pharmacology.

p73 can suppress the proliferation of cells that express mutant p53

Xinbin Chen, A. Willis, Jian-hui Zhu, 2003, Oncogene.

Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53*

Ling Song, Richard S. Jope, Xinbin Chen, 2003, Journal of Biological Chemistry.

The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability

Jin Zhang, Seong Jun Cho, Xinbin Chen, 2010, Nucleic Acids Res..

The Activation Domains, the Proline-rich Domain, and the C-terminal Basic Domain in p53 Are Necessary for Acetylation of Histones on the Proximal p21 Promoter and Interaction with p300/CREB-binding Protein*

Xinbin Chen, Gang Liu, T. Xia, 2003, The Journal of Biological Chemistry.

RNPC1, an RNA-binding Protein and a p53 Target, Regulates Macrophage Inhibitory Cytokine-1 (MIC-1) Expression through mRNA Stability

Seong-Jun Cho, Xinbin Chen, Tiffany Yin, 2013, The Journal of Biological Chemistry.

Glyoxalase II, a Detoxifying Enzyme of Glycolysis Byproduct Methylglyoxal and a Target of p63 and p73, Is a Pro-survival Factor of the p53 Family*

Xinbin Chen, Yang Xu, 2006, Journal of Biological Chemistry.

Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas.

Seong-Jun Cho, Wensheng Yan, Xinbin Chen, 2011, Genes & development.

The Unique NH2-terminally Deleted (ΔN) Residues, the PXXP Motif, and the PPXY Motif Are Required for the Transcriptional Activity of the ΔN Variant of p63*

Xinbin Chen, E. Helton, Jian-hui Zhu, 2006, Journal of Biological Chemistry.

The Activity of p53 Is Differentially Regulated by Brm- and Brg1-containing SWI/SNF Chromatin Remodeling Complexes*

Xinbin Chen, Jin Zhang, Yang Xu, 2007, Journal of Biological Chemistry.

Glycogen synthase kinase 3 promotes p 53 mRNA translation via phosphorylation of RNPC 1

Min Zhang, Seong-Jun Cho, Xinbin Chen, 2013 .

Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2012, Oncogene.

The RNA-binding Protein RNPC1 Stabilizes the mRNA Encoding the RNA-binding Protein HuR and Cooperates with HuR to Suppress Cell Proliferation*

Seong-Jun Cho, Xinbin Chen, Yong-Sam Jung, 2012, The Journal of Biological Chemistry.

The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73.

Xinbin Chen, Gang Liu, 2005, The Journal of biological chemistry.

p19ras Brings a New Twist to the Regulation of p73 by Mdm2

K. Harms, Xinbin Chen, 2006, Science's STKE.

The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress.

Yanhong Zhang, Xinbin Chen, Y. Qian, 2009, Cancer research.

PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2013, PloS one.

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation

Min Zhang, Seong-Jun Cho, Xinbin Chen, 2014, Oncotarget.

Syntaxin 6, a Regulator of the Protein Trafficking Machinery and a Target of the p53 Family, Is Required for Cell Adhesion and Survival*

Yanhong Zhang, Xinbin Chen, L. Shu, 2008, Journal of Biological Chemistry.

Disruption of the Rbm38-eIF4E Complex with a Synthetic Peptide Pep8 Increases p53 Expression.

B. Ma, Xinbin Chen, Mingyi Chen, 2019, Cancer research.

Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines

A. Borkhardt, Xinbin Chen, W. Woessmann, 2002, Cancer Chemotherapy and Pharmacology.

ΔNp73 Modulates Nerve Growth Factor-Mediated Neuronal Differentiation through Repression of TrkA

Xinbin Chen, Jin Zhang, 2007, Molecular and Cellular Biology.

Pirh2 E3 Ubiquitin Ligase Monoubiquitinates DNA Polymerase Eta To Suppress Translesion DNA Synthesis

A. Hakem, R. Hakem, Xinbin Chen, 2011, Molecular and Cellular Biology.

RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability

Seong-Jun Cho, Xinbin Chen, Jin Zhang, 2010, Nucleic acids research.

Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage

Ling Song, Richard S. Jope, Xinbin Chen, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The p53 family: Prospect for cancer gene therapy

Xinbin Chen, Jin Zhang, 2007, Cancer biology & therapy.

Functional p53 determines docetaxel sensitivity in prostate cancer cells

Yezi Zhu, R. deVere White, Qinghua Zhou, 2013, The Prostate.

TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response

Wensheng Yan, Xinbin Chen, Mingyi Chen, 2023, Cell Death & Disease.

Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1

Yanhong Zhang, Xinbin Chen, Mingyi Chen, 2019, Proceedings of the National Academy of Sciences.

DeltaNp73beta is active in transactivation and growth suppression.

Xinbin Chen, Hui Xiao, Gang Liu, 2004, Molecular and cellular biology.

Regulation of Mdm2 mRNA Stability by RNA-binding Protein RNPC1

Xinbin Chen, Jin Zhang, Enshun Xu, 2013, Oncotarget.

Aquaporin 3, a glycerol and water transporter, is regulated by p73 of the p53 family

Xinbin Chen, Xiangjian Zheng, 2001, FEBS letters.

RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense*

Yanhong Zhang, Wensheng Yan, Xinbin Chen, 2016, The Journal of Biological Chemistry.

PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38

Min Zhang, Xinbin Chen, Jin Zhang, 2015, Oncogene.

Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations.

Gang Liu, Ariane Scoumanne, Wensheng Yan, 2008, Cancer research.

Small Proline-Rich Protein 2A and 2D Are Regulated by the RBM38-p73 Axis and Associated with p73-Dependent Suppression of Chronic Inflammation

Xinbin Chen, Mingyi Chen, Jinhui Chen, 2021, Cancers.

Serine 195 phosphorylation in the RNA-binding protein Rbm38 increases p63 expression by modulating Rbm38's interaction with the Ago2–miR203 complex

Yanhong Zhang, Xinbin Chen, Xiuli Feng, 2018, The Journal of Biological Chemistry.

Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner

Seong-Jun Cho, Wensheng Yan, Xinbin Chen, 2017, Proceedings of the National Academy of Sciences.

The p53-estrogen receptor loop in cancer.

X Chen, Xinbin Chen, X. Chen, 2013, Current molecular medicine.

The potential tumor suppressor p73 differentially regulates cellular p53 target genes.

Xinbin Chen, Jieyuan Jiang, J. Zhu, 1998, Cancer research.

Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation.

X. Chen, C. Prives, Xinbin Chen, 1993, Genes & development.

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function

Xinbin Chen, X. Chen, Jin Zhang, 2009, Nucleic acids research.

Ferredoxin 1 is essential for embryonic development and lipid homeostasis

Xinbin Chen, Mingyi Chen, Shakur Mohibi, 2023, bioRxiv.

The common and distinct target genes of the p53 family transcription factors

X. Chen, K. Harms, Xinbin Chen, 2004, Cellular and Molecular Life Sciences CMLS.

The functional domains in p53 family proteins exhibit both common and distinct properties

X. Chen, K. Harms, Xinbin Chen, 2006, Cell Death and Differentiation.

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells.

X. Chen, C. Prives, L. Ko, 1996, Genes & development.

P63 regulates tubular formation via epithelial-to-mesenchymal transition

Wensheng Yan, Xinbin Chen, Wensheng Yan, 2014, Oncogene.

Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8

Wensheng Yan, Xinbin Chen, Jin Zhang, 2012, Oncogene.

DEC1 and MIC-1

Xinbin Chen, Yong-Sam Jung, Yingjuan Qian, 2012, Cell cycle.

The promise and obstacle of p53 as a cancer therapeutic agent.

Xinbin Chen, A. Willis, X. Chen, 2002, Current molecular medicine.

RNPC 1 modulates the RNA-binding activity of , and cooperates with , HuR to regulate p 21 mRNA stability

Seong-Jun Cho, Xinbin Chen, Jin Zhang, 2010 .

Characterization of Functional Domains Necessary for Mutant p53 Gain of Function*♦

Wensheng Yan, Xinbin Chen, 2010, The Journal of Biological Chemistry.

The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63

Xinbin Chen, E. Helton, X. Chen, 2008, Oncogene.

Protein methylation: a new mechanism of p53 tumor suppressor regulation.

X Chen, Xinbin Chen, X. Chen, 2008, Histology and histopathology.

Measuring Translation Efficiency by RNA Immunoprecipitation of Translation Initiation Factors.

Xinbin Chen, C. Lucchesi, Shakur Mohibi, 2021, Methods in molecular biology.