M. Żylicz

发表

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

A. Helwak, D. Walerych, M. Olszewski, 2009, Oncogene.

Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.

J. Jassem, R. Rosell, M. Żylicz, 2001, Lung cancer.

Hsp70 interactions with the p53 tumour suppressor protein

F. King, M. Żylicz, A. Wawrzynów, 2001, The EMBO journal.

High Guanine and Cytosine Content Increases mRNA Levels in Mammalian Cells

A. Helwak, Grzegorz Kudla, M. Żylicz, 2006, PLoS biology.

Function, evolution, and structure of J-domain proteins

Jason C. Young, P. Rios, A. Barducci, 2018, Cell Stress and Chaperones.

The grpE protein of Escherichia coli. Purification and properties.

C. Georgopoulos, D. Ang, M. Żylicz, 1987, The Journal of biological chemistry.

The Escherichia coli chaperones involved in DNA replication.

M. Żylicz, M.-J. Gething, R. Jaenicke, 1993, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Formation of the preprimosome protects λ O from RNA transcription-dependent proteolysis by ClpP/ClpX

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1998 .

Structure‐function analysis of the Escherichia coli GrpE heat shock protein.

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1996, The EMBO journal.

Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature

C. Georgopoulos, D. Ang, M. Żylicz, 1986, Journal of bacteriology.

Escherichia coli DnaK protein possesses a 5'-nucleotidase activity that is inhibited by AppppA

C. Georgopoulos, B. Bochner, M. Żylicz, 1986, Journal of bacteriology.

The mutant p 53 -ID 4 complex controls VEGFA isoforms by recruiting lncRNA MALAT 1

S. Bicciato, D. Bates, G. Blandino, 2017 .

The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication.

C. Georgopoulos, M. Żylicz, D. Wall, 1994, The Journal of biological chemistry.

P53 and K‐ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma

R. Dziadziuszko, J. Jassem, M. Żylicz, 2004, Cancer.

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

R. Dziadziuszko, J. Jassem, M. Żylicz, 2004, Lung cancer.

ATP Binding to Hsp90 Is Sufficient for Effective Chaperoning of p53 Protein*

D. Walerych, M. Gutkowska, M. Żylicz, 2010, The Journal of Biological Chemistry.

The Clp ATPases define a novel class of molecular chaperones

M. Żylicz, A. Wawrzynów, B. Banecki, 1996, Molecular microbiology.

Calf Thymus Hsc70 Protein Protects and Reactivates Prokaryotic and Eukaryotic Enzymes (*)

M. Żylicz, U. Hübscher, A. Ziemienowicz, 1995, The Journal of Biological Chemistry.

Real Time Kinetics of the DnaK/DnaJ/GrpE Molecular Chaperone Machine Action (*)

M. Żylicz, B. Banecki, 1996, The Journal of Biological Chemistry.

The Escherichia coli Chaperones Involved in DNA Replication

M. Żylicz, 1993 .

Divergent Effects of ATP on the Binding of the DnaK and DnaJ Chaperones to Each Other, or to Their Various Native and Denatured Protein Substrates (*)

M. Żylicz, A. Wawrzynów, 1995, The Journal of Biological Chemistry.

The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein.

C. Georgopoulos, M. Żylicz, D. Skowyra, 1991, The Journal of biological chemistry.

Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication.

C. Georgopoulos, D. Ang, M. Żylicz, 1990, The Journal of biological chemistry.

Structure-Function Analysis of the Zinc-binding Region of the ClpX Molecular Chaperone*

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 2001, The Journal of Biological Chemistry.

Purification and properties of the Escherichia coli dnaK replication protein.

C. Georgopoulos, M. Żylicz, 1984, The Journal of biological chemistry.

The nucleotide sequence of the Escherichia coli K12 dnaJ+ gene. A gene that encodes a heat shock protein.

J. King, C. Georgopoulos, E. Craig, 1986, The Journal of biological chemistry.

Purification and properties of the dnaJ replication protein of Escherichia coli.

C. Georgopoulos, M. Żylicz, T. Yamamoto, 1985, The Journal of biological chemistry.

Initiation of lambda DNA replication reconstituted with purified lambda and Escherichia coli replication proteins.

C. Georgopoulos, D. Ang, M. Żylicz, 1988, Biochimica et biophysica acta.

Bacteriophage λ DNA Replication and the Role of the Universally Conserved dnaK, dnaJ and grpE Heat Shock Proteins

C. Georgopoulos, D. Ang, M. Żylicz, 1992 .

Interactions between Phage λ Replication Proteins, λ DNA and Minicell Membrane

M. Żylicz, K. Taylor, 1981 .

Role of bacterial chaperones in DNA replication.

M. Żylicz, I. Konieczny, 1999, Genetic engineering.

Both the Escherichia coli Chaperone Systems, GroEL/GroES and DnaKIDnaJIGrpE, Can Reactivate Heat-treated RNA Polymerase

C. Georgopoulos, O. Fayet, M. Żylicz, 1993 .

The Biological Role of the Universally Conserved E. coli Heat Shock Proteins

C. Georgopoulos, D. Ang, O. Fayet, 1991 .

Structure-Function Analysis of the Zinc Finger Region of the DnaJ Molecular Chaperone*

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1996, The Journal of Biological Chemistry.

Hsp 90 chaperones wild-type p 53 tumor suppressor protein

J. Boros, A. Helwak, Grzegorz Kudla, 2022 .

Enzymology of the pre-priming steps in lambda dv DNA replication in vitro.

C. Georgopoulos, M. Żylicz, D. Skowyra, 1987, The Journal of biological chemistry.

Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease.

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1999, The Journal of biological chemistry.

Initiation of lambda DNA replication. The Escherichia coli small heat shock proteins, DnaJ and GrpE, increase DnaK's affinity for the lambda P protein.

C. Georgopoulos, M. Żylicz, J. Osipiuk, 1993, The Journal of biological chemistry.

Structural and functional relationships in DnaK and DnaK756 heat-shock proteins from Escherichia coli.

M. Żylicz, F. Tanfani, E. Bertoli, 1992, The Journal of biological chemistry.

Both ambient temperature and the DnaK chaperone machine modulate the heat shock response in Escherichia coli by regulating the switch between sigma 70 and sigma 32 factors assembled with RNA polymerase.

C. Georgopoulos, M. Żylicz, K. Liberek, 1995, The EMBO journal.

The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system.

C. Georgopoulos, M. Żylicz, J. Lebowitz, 1983, Proceedings of the National Academy of Sciences of the United States of America.

The dnaK protein modulates the heat-shock response of Escherichia coli

C. Georgopoulos, M. Żylicz, K. Tilly, 1983, Cell.

Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.

C. Georgopoulos, D. Ang, M. Żylicz, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Purification and Biochemical Properties of Saccharomyces cerevisiae Mdj1p, the Mitochondrial DnaJ Homologue*

C. Georgopoulos, M. Żylicz, K. Liberek, 1997, The Journal of Biological Chemistry.

9 Properties of the Heat Shock Proteins of Escherichia coli and the Autoregulation of the Heat Shock Response

C. Georgopoulos, D. Ang, M. Żylicz, 1994 .

The mutant p53‐ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

S. Bicciato, D. Bates, G. Blandino, 2017, EMBO Reports.

The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor.

T. Galitski, C. Georgopoulos, M. Żylicz, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Both the Escherichia coli chaperone systems, GroEL/GroES and DnaK/DnaJ/GrpE, can reactivate heat-treated RNA polymerase. Different mechanisms for the same activity.

C. Georgopoulos, O. Fayet, M. Żylicz, 1993, The Journal of biological chemistry.

Diverse and cancer type-specific roles of the p53 R248Q gain-of-function mutation in cancer migration and invasiveness

M. Olszewski, M. Żylicz, A. Zylicz, 2019, International journal of oncology.

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

M. Olszewski, M. Żylicz, A. Zylicz, 2012, PloS one.

Chaperoning the guardian of the genome. The two-faced role of molecular chaperones in p53 tumor suppressor action.

M. Żylicz, A. Zylicz, Bartosz Wawrzynów, 2018, Biochimica et biophysica acta. Reviews on cancer.

Biological role and regulation of the universally conserved heat shock proteins.

C. Georgopoulos, D. Ang, M. Żylicz, 1991, The Journal of biological chemistry.

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages

E. Gallo, G. Blandino, A. Sacconi, 2018, Breast Cancer Research.

Co‐chaperones Bag‐1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild‐type or mutant p53

M. Żylicz, A. Wawrzynów, J. Höhfeld, 2001, The EMBO journal.

The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase

C. Georgopoulos, M. Żylicz, M Zylicz, 1990, Journal of bacteriology.

Hsp90 Chaperones Wild-type p53 Tumor Suppressor Protein*

J. Boros, A. Helwak, Grzegorz Kudla, 2004, Journal of Biological Chemistry.

Role of the Escherichia coli DnaK and DnaJ heat shock proteins in the initiation of bacteriophage lambda DNA replication.

C. Georgopoulos, M. Żylicz, K. Liberek, 1988, Proceedings of the National Academy of Sciences of the United States of America.

DjlA Is a Third DnaK Co-chaperone of Escherichia coli, and DjlA-mediated Induction of Colanic Acid Capsule Requires DjlA-DnaK Interaction*

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 2001, The Journal of Biological Chemistry.

Cooperative Regulation of the Interferon Regulatory Factor-1 Tumor Suppressor Protein by Core Components of the Molecular Chaperone Machinery*

M. Żylicz, A. Zylicz, K. Ball, 2009, The Journal of Biological Chemistry.

Isolation and characterization of dnaJ null mutants of Escherichia coli

C. Georgopoulos, D. Ang, M. Żylicz, 1990, Journal of bacteriology.

MDM2 Chaperones the p53 Tumor Suppressor*

T. Hupp, M. Żylicz, A. Zylicz, 2007, Journal of Biological Chemistry.

Initiation of DNA replication on single-stranded DNA templates catalyzed by purified replication proteins of bacteriophage lambda and Escherichia coli.

C. Georgopoulos, M. Żylicz, J. Lebowitz, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Heat shock proteins create a signature to predict the clinical outcome in breast cancer

M. Żylicz, A. Zylicz, P. Biecek, 2019, Scientific Reports.

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation.

Patrycja Czerwińska, M. Wiznerowicz, M. Olszewski, 2017, Oncotarget.

Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance

M. Olszewski, M. Żylicz, A. Zylicz, 2021, Cancers.

Purification and properties of the NusB protein of Escherichia coli.

J. Greenblatt, C. Georgopoulos, M. Żylicz, 1988, The Journal of biological chemistry.

Mathematical modeling of heat shock protein synthesis in response to temperature change.

Zuzanna Szymańska, M. Żylicz, Maciej Zylicz, 2009, Journal of theoretical biology.

Escherichia coli dnaJ- and dnaK-gene products: synthesis in minicells and membrane-affinity.

M. Żylicz, K. Taylor, J. Nieradko, 1983, Biochemical and biophysical research communications.

Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli.

C. Georgopoulos, M. Żylicz, M Zylicz, 1993, The Journal of biological chemistry.

The ClpX heat‐shock protein of Escherichia coli, the ATP‐dependent substrate specificity component of the ClpP‐ClpX protease, is a novel molecular chaperone.

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1995, The EMBO journal.

Recognition, Targeting, and Hydrolysis of the λ O Replication Protein by the ClpP/ClpX Protease*

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1999, Journal of Biological Chemistry.

9 Properties of the Escherichia coli Heat Shock Proteins and Their Role in Bacteriophage λ Growth

C. Georgopoulos, D. Ang, M. Żylicz, 1990 .

The Conserved G/F Motif of the DnaJ Chaperone Is Necessary for the Activation of the Substrate Binding Properties of the DnaK Chaperone (*)

C. Georgopoulos, M. Żylicz, D. Wall, 1995, The Journal of Biological Chemistry.

Initiation of lambda DNA replication with purified host‐ and bacteriophage‐encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins.

C. Georgopoulos, D. Ang, M. Żylicz, 1989, The EMBO journal.

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms.

Č. Venclovas, M. Gutkowska, M. Żylicz, 2010, Biophysical chemistry.

ATP Hydrolysis Is Required for the DnaJ-dependent Activation of DnaK Chaperone for Binding to Both Native and Denatured Protein Substrates (*)

C. Georgopoulos, M. Żylicz, A. Wawrzynów, 1995, The Journal of Biological Chemistry.

Bacteriophage λ replication proteins: Formation of a mixed oligomer and binding to the origin of λ DNA

C. Georgopoulos, M. Żylicz, K. Taylor, 2004, Molecular and General Genetics MGG.

Phage λ integration protein: Synthesis in λ‐infected minicells and membrane affinity

M. Żylicz, E. Grzesiuk, K. Taylor, 1980 .

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation

Patrycja Czerwińska, M. Wiznerowicz, M. Olszewski, 2017, Oncotarget.

How I became a biochemist

M. Żylicz, 2008, IUBMB life.

Function, evolution, and structure of J-domain proteins

Jason C. Young, Nadinath B. Nillegoda, P. Rios, 2018, Cell Stress and Chaperones.

Zebrafish as experimental model to establish the contribution of mutant p53 and ID4 to breast cancer angiogenesis in vivo.

G. Blandino, M. Żylicz, G. Fontemaggi, 2018, Journal of thoracic disease.