H. Ananthaswamy

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Mutations in Nonmelanoma Skin Cancer of the Head and Neck : Molecular Evidence for Field Cancerization 1

M. Spitz, R. Weber, A. El‐Naggar, 2006 .

p53 mutation in squamous cell carcinomas from psoriasis patients treated with psoralen + UVA (PUVA).

L. Cerroni, H. Ananthaswamy, P. Wolf, 1997, The Journal of investigative dermatology.

UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53

A. El‐Naggar, M. Kripke, H. Ananthaswamy, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Genomic alterations in spontaneous and carcinogen-induced murine melanoma cell lines

H. Ananthaswamy, S. Bolshakov, V. Melnikova, 2004, Oncogene.

A model for UV-induction of skin cancer

Allal Ouhtit, H. Ananthaswamy, A. Ouhtit, 2001, Journal of biomedicine & biotechnology.

Photocarcinogenesis: an overview.

R. Tyrrell, H. Ananthaswamy, S. Ullrich, 1981, The Journal of investigative dermatology.

Mechanisms underlying the suppression of established immune responses by ultraviolet radiation.

M. Kripke, H. Ananthaswamy, A. A. Vink, 2002, The Journal of investigative dermatology.

p53 mutation in nonmelanoma skin cancers occurring in psoralen ultraviolet a-treated patients: evidence for heterogeneity and field cancerization.

R. Stern, H. Ananthaswamy, A. Nataraj, 2002, The Journal of investigative dermatology.

Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence

H. Ananthaswamy, O. Tavana, S. Ullrich, 2010, Cell cycle.

Models and mechanisms in malignant melanoma

H. Ananthaswamy, V. Melnikova, Cara L. Benjamin, 2007, Molecular carcinogenesis.

p53 protects against skin cancer induction by UV-B radiation

M. Kripke, H. Ananthaswamy, H. Muller, 1999, Oncogene.

Neoplastic transformation of C3H mouse embryo 10T1/2 cells by 8-methoxypsoralen plus UVA radiation.

H. Ananthaswamy, 1985, The Journal of investigative dermatology.

Protein Kinase C ε Is an Endogenous Photosensitizer That Enhances Ultraviolet Radiation-Induced Cutaneous Damage and Development of Squamous Cell Carcinomas1

H. Ananthaswamy, D. Mitchell, D. Wheeler, 2004, Cancer Research.

T1799A BRAF mutation is common in PUVA lentigines.

C. Massone, H. Kerl, L. Cerroni, 2006, The Journal of investigative dermatology.

T1796A BRAF mutation is absent in Merkel cell carcinoma

H. Kerl, L. Cerroni, H. Ananthaswamy, 2005, The British journal of dermatology.

Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens

M. Kripke, H. Ananthaswamy, S. Ullrich, 1997, Nature Medicine.

Detection and identification of activated oncogenes in human skin cancers occurring on sun-exposed body sites.

H. Ananthaswamy, J. Price, E. Bales, 1988, Cancer research.

Fas ligand: a sensor for DNA damage critical in skin cancer etiology.

M. Kripke, H. Ananthaswamy, L. Owen-Schaub, 1999, Science.

Cellular and molecular events leading to the development of skin cancer.

H. Ananthaswamy, V. Melnikova, 2005, Mutation research.

Molecular Basis of Skin Carcinogenesis

H. Ananthaswamy, G. Leone, A. Pacifico, 2017 .

Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin.

D. McConkey, H. Ananthaswamy, A. Ouhtit, 2000, The American journal of pathology.

Correlation between Ha-ras gene amplification and spontaneous metastasis in NIH 3T3 cells transfected with genomic DNA from human skin cancers

M. Tainsky, H. Ananthaswamy, J. Price, 1989, Clinical & Experimental Metastasis.

Deletion of the c‐Ha‐ras‐1 Allele in Human Skin Cancers

L. Applegate, H. Ananthaswamy, E. Bales, 1989, Molecular carcinogenesis.

Simultaneous transfer of tumorigenic and metastatic phenotypes by transfection with genomic DNA from a human cutaneous squamous cell carcinoma

H. Ananthaswamy, J. Price, E. Bales, 1988, Journal of cellular biochemistry.

Immune Response to Progresser Variants Derived from Transfection of an Ultraviolet Radiation-induced C 3 H Mouse Regressor Tumor Cell Line with Activated Harvey-mi Oncogene 1

W. Pierceall, H. Ananthaswamy, J. Price, 2006 .

Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas

W. Pierceall, H. Ananthaswamy, T. Mukhopadhyay, 1991, Molecular carcinogenesis.

Inhibition of colony formation in agarose of metastatic human breast carcinoma and melanoma cells by synthetic glycoamine analogs

H. Ananthaswamy, J. Price, G. Glinsky, 1996, Clinical & Experimental Metastasis.

Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras.

I. Fidler, G. Schackert, H. Ananthaswamy, 1989, Cancer research.

Mass spectrometric proteomics profiles of in vivo tumor secretomes: Capillary ultrafiltration sampling of regressive tumor masses

Chun-Ming Huang, C. Elmets, H. Ananthaswamy, 2006, Proteomics.

Presence of human papilloma virus type 16 DNA sequences in human nonmelanoma skin cancers.

W. Pierceall, H. Ananthaswamy, L. Goldberg, 1991, The Journal of investigative dermatology.

Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase

H. Ananthaswamy, S. Bolshakov, A. Santamaria, 2003, Oncogene.

Presentation of endogenous tumor antigens to CD4+ T lymphocytes by murine melanoma cells transfected with major histocompatibility complex class II genes

Peter W. Chen, H. Ananthaswamy, S. Ullrich, 1994, Journal of leukocyte biology.

Oncogene regulation of endonuclease activation in apoptosis.

D. McConkey, H. Ananthaswamy, J. Trent, 1995, Cancer letters.

Afferent and efferent specificity in the induction and elicitation of parental cross-protective immunity by an immunogenic murine tumor variant: associative recognition of a unique tumor-specific antigen on somatic cell hybrids.

H. Ananthaswamy, S. Legrue, W. Simcik, 1989, Cancer research.

Photocarcinogenesis and susceptibility to UV radiation in the v-Ha-ras transgenic Tg.AC mouse.

R. Tennant, J. French, H. Ananthaswamy, 1998, The Journal of investigative dermatology.

Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis.

C. Bucana, H. Ananthaswamy, P. Wolf, 2006, The American journal of pathology.

Detection of mutations and polymorphisms in the p53 tumor suppressor gene by single‐strand conformation polymorphism analysis

H. Ananthaswamy, S. Bolshakov, L. S. Kutach, 1999, Electrophoresis.

Sunlight and skin cancer

H. Ananthaswamy, 2001, Journal of biomedicine & biotechnology.

UV-A Fingerprint Mutations in Human Skin Cancer¶

H. Ananthaswamy, G. Halliday, R. Barnetson, 2005 .

Mechanisms underlying UV‐induced immune suppression: implications for sunscreen design

M. Kripke, H. Ananthaswamy, S. Ullrich, 2002, Experimental dermatology.

High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: evidence for strand bias and tumor heterogeneity.

W. Pierceall, S. Kanjilal, K. Cummings, 1993, Cancer research.

An endomitotic effect of a cell cycle mutation of Saccharomyces cerevisiae.

R. Mortimer, D. Schild, H. Ananthaswamy, 1981, Genetics.

p53 and Fas ligand are required for psoralen and UVA-induced apoptosis in mouse epidermal cells

M. Kapoor, D. McConkey, G. Lozano, 2002, Cell Death and Differentiation.

p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas.

S. Lippman, S. Strom, M. Kripke, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Mutations in Human Aggressive and Nonaggressive Basal and Squamous Cell Carcinomas 1

S. Lippman, S. Strom, M. Kripke, 2003 .

Oncogenes and Tumor Suppressor Genes in Photocarcinogenesis

S. Kanjilal, H. Ananthaswamy, Honnavara N. Ananthaswamy, 1996, Photochemistry and photobiology.

Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis

H. Ananthaswamy, C. Conti, A. Ouhtit, 1999, Oncogene.

Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells.

H. Ananthaswamy, D. S. Kaba, P. Chen, 1990, Cancer research.

Generation of antigenic variants from a nonantigenic murine tumor cell line by transfection with a gene encoding a novel tumor-specific transplantation antigen.

M. Kripke, H. Ananthaswamy, H. Schreiber, 1989, Cancer research.

Relationship between expression of tumor-specific transplantation antigens and neoplastic transformation in an ultraviolet radiation-induced murine skin cancer.

H. Ananthaswamy, 1986, Cancer research.

Differential regulation of endogenous endonuclease activation in isolated murine fibroblast nuclei by ras and bcl-2.

T. McDonnell, D. McConkey, H. Ananthaswamy, 1995, Oncogene.

A Highly Active Homeobox Gene Promoter Regulated by Ets and Sp1 Family Members in Normal Granulosa Cells and Diverse Tumor Cell Types*

H. Ananthaswamy, M. Wilkinson, M. Rao, 2002, The Journal of Biological Chemistry.

N-ras mutation in ultraviolet radiation-induced murine skin cancers.

W. Pierceall, M. Kripke, H. Ananthaswamy, 1992, Cancer research.

Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis.

H. Ananthaswamy, A. Ouhtit, H. Muller, 2000, The American journal of pathology.

Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development

S. Chimenti, K. Peris, H. Ananthaswamy, 2005, Oncogene.

UV‐A Fingerprint Mutations in Human Skin Cancer ¶

H. Ananthaswamy, G. Halliday, R. Barnetson, 2005, Photochemistry and photobiology.

Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: induction of bcl-2, c-myc, and manganese superoxide dismutase in resistant cells.

T. McDonnell, H. Ananthaswamy, M. Marin, 1994, Oncogene.

Regulated expression of tumor-specific and MHC class I antigens in an ultraviolet radiation-induced murine skin cancer.

H. Ananthaswamy, 1988, The Journal of investigative dermatology.

Inhibition of solar simulator-induced p53 mutations and protection against skin cancer development in mice by sunscreens.

C. Bucana, M. Kripke, H. Ananthaswamy, 1999, The Journal of investigative dermatology.

Sunscreen effects on UV-induced immune suppression.

M. Kripke, H. Ananthaswamy, S. Ullrich, 1999, The journal of investigative dermatology. Symposium proceedings.

Differential Tumor Biology Effects of Double-Initiation in a Mouse Skin Chemical Carcinogenesis Model Comparing Wild Type versus Protein Kinase Cepsilon Overexpression Mice

H. Ananthaswamy, D. Wheeler, A. Verma, 2007, Toxicologic pathology.

Rejection of K1735 murine melanoma in syngeneic hosts requires expression of MHC class I antigens and either class II antigens or IL-2.

H. Ananthaswamy, P. Chen, P. Chen, 1993, Journal of immunology.

Bcl-2 oncogene blocks differentiation and extends viability but does not immortalize normal human keratinocytes.

T. McDonnell, H. Ananthaswamy, A. Nataraj, 1994, International journal of oncology.

Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis.

H. Ananthaswamy, S. Ullrich, Y. Matsumura, 2004, The American journal of pathology.

Inhibition of UV-induced p53 mutations by sunscreens: implications for skin cancer prevention.

M. Kripke, H. Ananthaswamy, S. Ullrich, 1998, The journal of investigative dermatology. Symposium proceedings.

Toxic effects of ultraviolet radiation on the skin.

Yasuhiro Matsumura, H. Ananthaswamy, Y. Matsumura, 2004, Toxicology and applied pharmacology.

The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: a role for UVA in human skin carcinogenesis.

H. Ananthaswamy, G. Halliday, M. Wheeler, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of UV‐induced p53 mutations and skin cancers by sunscreens: implication for skin cancer prevention

M. Kripke, H. Ananthaswamy, S. Ullrich, 2002, Experimental dermatology.

Tumor Suppressor Gene : A Critical Molecular Target for UV Induction and Prevention of Skin Cancer †

M. Kripke, H. Ananthaswamy, S. Ullrich, 2007 .

Molecular mechanisms of photocarcinogenesis.

H. Ananthaswamy, Y. Matsumura, 2002, Frontiers in bioscience : a journal and virtual library.

Advantages of Using Hairless Mice Versus Haired Mice to Test Sunscreen Efficacy Against Photoimmune Suppression¶

M. Kripke, H. Ananthaswamy, S. Ullrich, 2003, Photochemistry and photobiology.

Ultraviolet a radiation suppresses an established immune response: implications for sunscreen design.

M. Kripke, H. Ananthaswamy, S. Ullrich, 2001, The Journal of investigative dermatology.

p53 GENE MUTATIONS AND PHOTOCARCINOGENESIS

H. Ananthaswamy, A. Nataraj, Jonathan C. Trent Ii, 1995, Photochemistry and photobiology.

Ras gene mutation and amplification in human nonmelanoma skin cancers

W. Pierceall, M. Tainsky, H. Ananthaswamy, 1991, Molecular carcinogenesis.

Direct Comparison of DMA Damage, Isomerization of Urocanic Acid and Edema in the Mouse Produced by Three Commonly Used Artificial UV Light Sources

M. Kripke, H. Ananthaswamy, A. Fourtanier, 1999, Photochemistry and photobiology.

In vitro transformation of primary cultures of neonatal BALB/c mouse epidermal cells with ultraviolet-B radiation.

M. Kripke, H. Ananthaswamy, 1981, Cancer research.

Ultraviolet Radiation as a Carcinogen

H. Ananthaswamy, F. Gruijl, 2010 .

MOLECULAR MECHANISMS OF ULTRAVIOLET RADIATION CARCINOGENESIS

W. Pierceall, H. Ananthaswamy, Honnavara N. Ananthaswamy, 1990, Photochemistry and photobiology.

Hypersensitivity of skin fibroblasts from basal cell nevus syndrome patients to killing by ultraviolet B but not by ultraviolet C radiation.

L. Applegate, H. Ananthaswamy, L. Goldberg, 1990, Cancer research.

Correlation of growth capacity of cells in hard agarose with successful transfection by the activated c-Ha-ras oncogene and in vivo proliferative capacity at metastatic sites.

I. Fidler, H. Ananthaswamy, R. Radinsky, 1991, Anticancer research.

Photoreactivation of ultraviolet radiation-induced pyrimidine dimers in neonatal BALB/c mouse skin.

M. S. Fisher, H. Ananthaswamy, 1981, Cancer research.

Etiology of Nonmelanocytic Skin Cancer

H. Ananthaswamy, Cara L. Benjamin, 2016 .

P53 protein and pathogenesis of melanoma and nonmelanoma skin cancer.

H. Ananthaswamy, V. Melnikova, Cara L. Benjamin, 2008, Advances in experimental medicine and biology.

p53 and the pathogenesis of skin cancer.

H. Ananthaswamy, Cara L. Benjamin, 2007, Toxicology and applied pharmacology.

Oncogenic potential of BRAF versus RAS.

H. Ananthaswamy, Cara L. Benjamin, 2008, Cancer letters.

Impact of Bcl-2 and Ha-ras on keratinocytes in organotypic culture.

T. McDonnell, M. Kripke, H. Ananthaswamy, 2001, The Journal of investigative dermatology.

p53 Protein and Nonmelanoma Skin Cancer

H. Ananthaswamy, V. Melnikova, 2006 .

Comparison of Wound Closure after Burn and Cold Injury in Human Skin Equivalents

P. Pollock, H. Ananthaswamy, U. Harper, 2006 .

Dual blockade of EGFR and ERK1/2 phosphorylation potentiates growth inhibition of breast cancer cells

D. Lev, H. Ananthaswamy, V. Melnikova, 2004, British Journal of Cancer.

p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma.

Jeffrey E. Lee, Hongbing Shen, M. Spitz, 2003, The Journal of investigative dermatology.

Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers.

H. Ananthaswamy, A. Nataraj, H. Black, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Exposure of melanoma cells to dacarbazine results in enhanced tumor growth and metastasis in vivo.

D. Lev, H. Ananthaswamy, M. Bar‐eli, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Molecular alterations in human skin tumors.

W. Pierceall, H. Ananthaswamy, 1992, Progress in clinical and biological research.

Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine

H. Ananthaswamy, Y. Matsumura, 2002, Expert Reviews in Molecular Medicine.

Rejection of murine melanoma-cells transfected with the intercellular-adhesion molecule-1 gene.

H. Ananthaswamy, V. Shreedhar, P. Chen, 1995, International Journal of Oncology.

Quantitative proteomes and in vivo secretomes of progressive and regressive UV‐induced fibrosarcoma tumor cells: Mimicking tumor microenvironment using a dermis‐based cell‐trapped system linked to tissue chamber

Yu-Tseung Liu, C. Elmets, Yun-Ru Chen, 2007, Proteomics.

Loss of CDKN2A and p14ARF expression occurs frequently in human nonmelanoma skin cancers

S. Chimenti, K. Peris, H. Ananthaswamy, 2007, The British journal of dermatology.

Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53.

H. Ananthaswamy, K. Xie, W. Jiang, 1999, Cancer research.

Advances in Brief Direct Correlation between Nitric Oxide Synthase II Inducibility and Metastatic Ability of UV-2237 Murine Fibrosarcoma Cells Carrying Mutant p 53 1

H. Ananthaswamy, Suyun Huang, K. Xie, 2000 .

Transformation of NIH3T3 cells by transfection with UV-irradiated human c-Ha-ras-1 proto-oncogene DNA.

W. Pierceall, H. Ananthaswamy, 1991, Oncogene.

Photocarcinogenesis — models and mechanisms

H. Mukhtar, H. Ananthaswamy, P. Forbes, 1999, Photodermatology, photoimmunology & photomedicine.

p53 mutations in nonmelanoma skin cancer of the head and neck: molecular evidence for field cancerization.

M. Spitz, R. Weber, A. El‐Naggar, 1995, Cancer research.

p53 Mutations in Hairless SKH‐hr1 Mouse Skin Tumors Induced by a Solar Simulator

M. Kripke, H. Ananthaswamy, A. Fourtanier, 1998, Photochemistry and photobiology.

Mechanisms of induction of skin cancer by UV radiation.

H. Ananthaswamy, A. Ouhtit, H. Soehnge, 1997, Frontiers in bioscience : a journal and virtual library.

Ras signaling in tumor necrosis factor‐induced apoptosis.

D. McConkey, H. Ananthaswamy, J. Trent, 1996, The EMBO journal.

Oncogenic potential of BRAF versus RAS.

H. Ananthaswamy, Cara L. Benjamin, 2008, Cancer Letters.

UVB-induced experimental carcinogenesis: dysregulation of apoptosis and p53 signalling pathway

H. Ananthaswamy, A. Ouhtit, H. Konrad Muller, 2000, Redox report : communications in free radical research.

Photocarcinogenesis: an overview.

H. Ananthaswamy, J. Cleaver, P. Forbes, 1997, Journal of photochemistry and photobiology. B, Biology.

Inverse Relationship Between Increased Apoptosis and Decreased Skin Cancer in UV-irradiated CD1d−/− Mice¶

H. Ananthaswamy, S. Ullrich, Y. Matsumura, 2005, Photochemistry and photobiology.

Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas.

H. Ananthaswamy, D. Mitchell, D. Wheeler, 2004, Cancer research.