H. Schackert

G. Schackert, H. Schackert, D. Krex, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

t(11;19)(q21;p12~p13.11) and MECT1-MAML2 fusion transcript expression as a prognostic marker in infantile lung mucoepidermoid carcinoma.

H. Schackert, T. Liehr, B. Mohr, 2007, Journal of pediatric surgery.

Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas.

I. König, A. Ziegler, H. Schackert, 2007, Oral oncology.

Expression ofTRAILand Its Receptors in Human Brain Tumors

G. Schackert, H. Schackert, S. Frank, 1999 .

Expression of TRAIL and its receptors in human brain tumors.

G. Schackert, H. Schackert, S. Frank, 1999, Biochemical and biophysical research communications.

Interaction of RET proto‐oncogene codon 609 germline mutations with RET haplotypes characterized by c.135G>A alleles modifying MEN 2A or HSCR phenotypes

W. Hohenberger, H. Schackert, H. Hümmer, 2004, American journal of medical genetics. Part A.

Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: A comprehensive analysis of 3,671 families

M. Loeffler, C. Engel, H. Schackert, 2014, International journal of cancer.

Analysis of EPCAM protein expression in diagnostics of Lynch syndrome.

A. Voigt, M. Kloor, M. von Knebel Doeberitz, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study.

Julie O. Culver, L. Kiemeney, M. Kloor, 2011, The Lancet. Oncology.

Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer.

I. Tomlinson, L. Vreede, A. V. van Kessel, 2010, Gastroenterology.

LightCycler assay in the analysis of haplotypes of the type 2 diabetes susceptibility gene CAPN10.

P. Schwarz, H. Schackert, H. Görgens, 2003, Clinical chemistry.

Monitoring gene therapy with cytosine deaminase: in vitro studies using tritiated-5-fluorocytosine.

G. van Kaick, U. Haberkorn, J. Gebert, 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients

M. Kloor, W. Schmiegel, C. Engel, 2008, European Journal of Human Genetics.

Association between c135G/A genotype and RET proto-oncogene germline mutations and phenotype of Hirschsprung's disease

Dietmar Roesner, Andreas Ziegler, Matthias Schreiber, 2002, The Lancet.

One-step analysis of ten functional haplotype combinations of the basic RET promoter with a LightCycler assay.

H. Schackert, H. Görgens, G. Fitze, 2004, Clinical chemistry.

Assoziation funktioneller Haplotypen des RET-Protoonkogen Promotors mit dem Morbus Hirschsprung Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease

A. Ziegler, M. Gossen, H. Schackert, 2004 .

BRCA2germline mutations among early onset breast cancer patients unselected for family history of the disease

J. Chang-Claude, C. Jacobi, H. Schackert, 2000, Journal of medical genetics.

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are risk factors for colorectal cancer.

L. Vreede, R. Kuiper, C. V. van Ravenswaaij-Arts, 2013, Gastroenterology.

N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer

C. Engel, H. Schackert, H. Saeger, 2006, International Journal of Colorectal Disease.

N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).

M. von Knebel Doeberitz, C. Engel, J. Rüschoff, 2006, Cancer letters.

Lack of Association Between Endoglin Intron 7 Insertion Polymorphism and Intracranial Aneurysms in a White Population: Evidence of Racial/Ethnic Differences

G. Schackert, H. Schackert, D. Krex, 2001, Stroke.

Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer.

M. Kloor, M. von Knebel Doeberitz, M. Loeffler, 2010, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies.

M. Kloor, M. von Knebel Doeberitz, C. Strassburg, 2018, Gastroenterology.

Microsatellite stable colorectal cancers in clinically suspected hereditary nonpolyposis colorectal cancer patients without vertical transmission of disease are unlikely to be caused by biallelic germline mutations in MYH.

H. Schackert, S. Krüger, H. Görgens, 2006, The Journal of molecular diagnostics : JMD.

Occult endometrial cancer and decision making for prophylactic hysterectomy in hereditary nonpolyposis colorectal cancer patients.

H. Schackert, H. Saeger, W. Distler, 2006, Gynecologic oncology.

ADAM9 als prognostischer Marker beim humanen duktalen Pankreaskarzinom ADAM9 is a prognostic marker in human ductal pancreatic cancer

R. Grützmann, H. Schackert, S. Kersting, 2004 .

Genetic alterations of the tumor suppressor gene PTEN/MMAC1 in human brain metastases.

G. Schackert, H. Schackert, S. Sobottka, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing

L. Vissers, A. Hoischen, J. Lupski, 2017, European Journal of Human Genetics.

DHPLC mutation analysis of the hereditary nonpolyposis colon cancer (HNPCC) genes hMLH1 and hMSH2.

T. Meitinger, H. Schackert, W. Ballhausen, 2001, Journal of biochemical and biophysical methods.

Deciphering the genetics of hereditary non-syndromic colorectal cancer

P. Broderick, J. Vijayakrishnan, K. Sullivan, 2008, European Journal of Human Genetics.

Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype.

W. Foulkes, G. Capellá, I. Tomlinson, 2019, Cancer cell.

Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras.

I. Fidler, G. Schackert, H. Ananthaswamy, 1989, Cancer research.

TLR4 and IL-18 gene variants in aggressive periodontitis.

A. Ziegler, H. Schackert, T. Hoffmann, 2008, Journal of clinical periodontology.

CARD15 gene variants in aggressive periodontitis.

H. Schackert, T. Hoffmann, H. Görgens, 2006, Journal of clinical periodontology.

Association of germline mutations and polymorphisms of the RET proto-oncogene with idiopathic congenital central hypoventilation syndrome in 33 patients

H. Schackert, M. Schläfke, E. Kuhlisch, 2003, Journal of medical genetics.

An unusual case of Cowden syndrome associated with ganglioneuromatous polyposis

E. Schröck, D. Aust, A. Rump, 2016, Hereditary Cancer in Clinical Practice.

Können die molekulargenetischen Kenntnisse aus dem Studium des erblichen Karzinoms auf das sporadische kolorektale Karzinom übertragen werden? / Is Molecular Genetic Knowledge of Hereditary Colorectal Carcinomas Transferable to Sporadic Carcinomas?

H. Schackert, H. Saeger, S. Pistorius, 2001 .

Albright’s Hereditary Osteodystrophy Associated with Cerebellar Pilocytic Astrocytoma: Coincidence or Genetic Relationship?

G. Schackert, H. Schackert, A. Huebner, 2001, Hormone Research in Paediatrics.

Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.

M. Kloor, R. Houlston, K. Hemminki, 2008, Cancer letters.

Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.

M. von Knebel Doeberitz, C. Engel, J. Rüschoff, 2005, The Lancet. Oncology.

Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases

I. Fidler, H. Schackert, 1989, International journal of cancer.

Procedure for Neonatal Screening for Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

M. Knip, G. Schackert, A. Ruokonen, 2001, Hormone Research in Paediatrics.

Complete homozygous deletion of CTSC in an Iranian family with Papillon–Lefèvre syndrome

P. Hoffmann, H. Schackert, Stephanie Kannen, 2014, International journal of dermatology.

Functional Cathepsin C mutations cause different Papillon-Lefèvre syndrome phenotypes.

H. Schackert, P. Eickholz, T. Hoffmann, 2008, Journal of clinical periodontology.

Combined detection of CD44 isoforms by exon-specific RT-PCR and immunohistochemistry in primary human brain tumors and brain metastases.

G. Schackert, H. Schackert, H. Rihs, 1996, Biochemical and biophysical research communications.

Screening for large rearrangements of the BRCA1 gene in German breast or ovarian cancer families using semi‐quantitative multiplex PCR method

D. Horn, H. Schackert, S. Scherneck, 2003, Human mutation.

Therapy of hematogenous melanoma brain metastases with endostatin.

P. Black, G. Schackert, R. Carroll, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes

P. Bork, T. Doerks, S. Moebus, 2018, International journal of cancer.

Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1

S. Boué, H. Schackert, R. Büttner, 2008, European Journal of Human Genetics.

The putative tumor suppressor gene FHIT at 3p14.2 is rarely affected by loss of heterozygosity in primary human brain tumors.

G. Schackert, H. Schackert, J. Plaschke, 1997, Cancer research.

Quantitative Differences between Aberrant Transcripts Which Occur as Common Isoforms and due to Mutation-based Exon Skipping of the Mismatch Repair Gene hMLH1

H. Schackert, H. Saeger, J. Plaschke, 1999, Clinical chemistry and laboratory medicine.

HNPCC-associated small bowel cancer: clinical and molecular characteristics.

K. Schulmann, W. Schmiegel, C. Engel, 2005, Gastroenterology.

Novel Mutations in the Cathepsin C Gene in Patients with Pre-pubertal Aggressive Periodontitis and Papillon-Lefèvre Syndrome

H. Schackert, P. Eickholz, T. Hoffmann, 2004, Journal of dental research.

Deleterious Germline BLM Mutations and the Risk for Early-onset Colorectal Cancer

A. Hoischen, I. Nagtegaal, C. Gilissen, 2015, Scientific Reports.

Value of upper gastrointestinal endoscopy for gastric cancer surveillance in patients with Lynch syndrome

M. Kloor, C. Strassburg, M. Loeffler, 2020, International journal of cancer.

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Aung Ko Win, P. Møller, E. Hovig, 2019, Genetics in Medicine.

Value of EGD for gastric cancer surveillance in patients with hereditary non-polyposis colorectal cancer (HNPCC) or Lynch syndrome (LS).

M. Kloor, C. Strassburg, M. Loeffler, 2018 .

Clinical characteristics and EGD surveillance in Lynch-syndrome patients with small bowel/duodenal carcinomas.

M. Kloor, C. Strassburg, M. Loeffler, 2018 .

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Aung Ko Win, P. Møller, E. Hovig, 2020, Genetics in Medicine.

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.

M. Kloor, M. Loeffler, J. Gebert, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer

M. Kloor, M. Loeffler, P. Kienle, 2006, International journal of cancer.

[Inherited tumors of the gastrointestinal tract. Diagnosis and therapeutic aspects].

H. Schackert, H. Saeger, S. Pistorius, 2007, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

Evidence that TSG101 aberrant transcripts are PCR artifacts.

G. Schackert, H. Schackert, H. Saeger, 1998, Biochemical and biophysical research communications.

Development of immunogenic colorectal cancer cell lines for vaccination: expression of CD80 (B7.1) is not sufficient to restore impaired primary T cell activation in vitro.

J. Gebert, H. Schackert, S. Meuer, 1995, European journal of cancer.

RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system

C. Pilarsky, R. Grützmann, G. Schackert, 2011, International Journal of Colorectal Disease.

Compound effect of PHOX2B and RET gene variants in congenital central hypoventilation syndrome combined with Hirschsprung disease

I. König, A. Ziegler, H. Schackert, 2008, American journal of medical genetics. Part A.

Comparative genetic analysis of metachronous anaplastic oligoastrocytomas with extended recurrence-free interval

R. Martínez, G. Schackert, H. Schackert, 2005, Journal of Neuro-Oncology.

Doublex sequencing in molecular diagnosis of hereditary diseases.

W. Ansorge, H. Schackert, H. Voss, 1998, BioTechniques.

Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer.

H. Schackert, U. Eckelt, E. Kuhlisch, 2002, Oral oncology.

Transmission of glioblastoma multiforme through liver transplantation

G. Schackert, H. Schackert, G. Haroske, 1998, The Lancet.

Various Penetrance of Familial Medullary Thyroid Carcinoma in Patients With RET Protooncogene Codon 790/791 Germline Mutations

J. Bredow, H. Schackert, H. Saeger, 2002, Annals of surgery.

Techniken und Strategien zur Identifizierung von Mutationen, die zum Hereditary Nonpolyposis Colorectal Cancer Syndrome (HNPCC Syndrom) prädisponieren

H. Schackert, H. Saeger, S. Frank, 1996 .

Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer

J. Rüschoff, H. Schackert, R. Fishel, 2000, International journal of cancer.

Gene therapy and gastrointestinal cancer: concepts and clinical facts

H. Schackert, M. Hauses, 1999, Langenbeck's Archives of Surgery.

Detection of cytosine deaminase in genetically modified tumor cells by specific antibodies.

J. Gebert, C. Herfarth, H. Schackert, 1997, Human gene therapy.

Identification of Uncommon Chromosomal Aberrations in the Neuroglioma Cell Line H4 by Spectral Karyotyping

G. Schackert, H. Schackert, G. Ehninger, 2001, Journal of Neuro-Oncology.

Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck

K. Friedrich, H. Schackert, U. Eckelt, 2004, Head & neck.

Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin

M. Kloor, K. Hemminki, A. Naccarati, 2011, PloS one.

Microsatellite instability of selective target genes in HNPCC-associated colon adenomas

Holger Vogelsang, Matthias Kloor, M. Kloor, 2005, Oncogene.

Hereditary colorectal cancer: clinical consequences of predictive molecular testing

H. Schackert, H. Saeger, M. Hahn, 1999, International Journal of Colorectal Disease.

Molecular biology of colorectal cancer and clinical consequences for colorectal cancer syndromes

H. Schackert, M. Hahn, O. Koufaki, 1998, Langenbeck's Archives of Surgery.

Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics.

J. Rüschoff, H. Schackert, J. Schlegel, 1997, The American journal of pathology.

Frequent loss of the CDKN2C (p18INK4c) gene product in pituitary adenomas

G. Schackert, H. Schackert, M. Kirsch, 2009, Genes, chromosomes & cancer.

Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy

S. Stevanović, E. Rieber, G. Schackert, 2007, British Journal of Cancer.

Cancer Risks for PMS2-Associated Lynch Syndrome.

Aung Ko Win, M. von Knebel Doeberitz, P. Møller, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome.

W. Schmiegel, C. Engel, H. Schackert, 2013, Deutsches Arzteblatt international.

Physical and functional characterization of the human LGI1 gene and its possible role in glioma development

G. Schackert, H. Schackert, G. Ehninger, 2002, Acta Neuropathologica.

Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor

M. Kloor, D. Aust, J. Gebert, 2006, European Journal of Human Genetics.

Rare Occurrence of PHOX2b Mutations in Sporadic Neuroblastomas

I. König, H. Schackert, R. Kappler, 2008, Journal of pediatric hematology/oncology.

Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3.

Michael Krawczak, Barbara Burwinkel, Rongxi Yang, 2014, Carcinogenesis.

Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12 p 12 . 3

Chen, Buch, W. Schmiegel, 2014 .

Combined molecular and clinical approaches for the identification of families with familial adenomatous polyposis coli.

M. von Knebel Doeberitz, J. Gebert, C. Herfarth, 1999, Annals of surgery.

TCF-3, 4 protein expression correlates with β-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers

H. Schackert, S. Krüger, P. Baláž, 2010, International Journal of Colorectal Disease.

Risks of less common cancers in proven mutation carriers with lynch syndrome.

Markus Loeffler, Christoph Engel, Magnus von Knebel Doeberitz, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Molecular Mechanisms Associated with Chromosomal and Microsatellite Instability in Sporadic Glioblastoma multiforme

R. Martínez, G. Schackert, H. Schackert, 2004, Oncology.

Loss of BRCA2 correlates with reduced long-term survival of sporadic breast cancer patients.

H. Schackert, H. Saeger, R. Koch, 2004, Anticancer research.

Loss of heterozygosity accumulation in primary breast carcinomas and additionally in corresponding distant metastases is associated with poor outcome.

G. Schackert, H. Schackert, H. Saeger, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.

C. Pilarsky, R. Grützmann, B. Sipos, 2004, Neoplasia.

Identification of candidate predisposing copy number variants in familial and early‐onset colorectal cancer patients

A. V. van Kessel, R. Kuiper, H. Schackert, 2011, International journal of cancer.

Recurrence and variability of germline EPCAM deletions in Lynch syndrome

Julie O. Culver, M. Kloor, P. Hutter, 2011, Human mutation.

Frequent Loss of Heterozygosity at the 19p13.3 Locus Without LKB1/STK11 Mutations in Human Carcinoma Metastases to the Brain

G. Schackert, H. Schackert, S. Sobottka, 2000, Journal of Neuro-Oncology.

Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling

H. Friess, C. Pilarsky, G. Kristiansen, 2008, Journal of cellular and molecular medicine.

Systemic immunity against a murine colon tumor (CT‐26) produced by immunization with syngeneic cells expressing a transfected viral gene product

B. Vogelstein, E. Fearon, G. Schackert, 1989, International journal of cancer.

Immune reactions induced by interleukin-2 transfected colorectal cancer cells in vitro: predominant induction of lymphokine-activated killer cells

J. Gebert, H. Schackert, S. Meuer, 2004, Journal of Molecular Medicine.

Inhibition of malignant glioma cell growth by a survivin mutant retrovirus.

E. Rieber, H. Schackert, M. Rieger, 2004, Human gene therapy.

Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme

H. Schackert, G. Baretton, G. Schackert, 2005, Journal of Cancer Research and Clinical Oncology.

Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implications.

M. Kloor, C. Cruciat, M. Boutros, 2011, International journal of molecular epidemiology and genetics.

Biallelic MLH1 SNP cDNA expression or constitutional promoter methylation can hide genomic rearrangements causing Lynch syndrome

M. Kloor, K. Schulmann, H. Schackert, 2011, Journal of Medical Genetics.

Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression

M. Scheunemann, P. Brust, U. Haberkorn, 2001, European Journal of Nuclear Medicine.

Microsatellite instability analysis: a multicenter study for reliability and quality control.

J. Gebert, J. Rüschoff, H. Schackert, 1997, Cancer research.

Combined molecular and clinical approach for decision making for surgery in HNPCC patients: a report on three cases in two families

H. Schackert, H. Saeger, J. Plaschke, 2001, International Journal of Colorectal Disease.

ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma

C. Pilarsky, R. Grützmann, B. Sipos, 2004, British Journal of Cancer.

TLR4 and IL-18 Gene Variants in Chronic Periodontitis: Impact on Disease Susceptibility and Severity

H. Schackert, T. Hoffmann, H. Görgens, 2009, Immunological investigations.

An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and regenerating blastema cDNA libraries

Bianca Habermann, Michael Volkmer, B. Habermann, 2004, Genome Biology.

Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.

C. Engel, H. Schackert, H. Saeger, 2007, Cancer letters.

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers

R. van Hillegersberg, C. Caldas, D. Huntsman, 2015, Journal of Medical Genetics.

Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue

C. Sutter, G. Evans, J. Gebert, 2004, Human mutation.

Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6

M. Kerscher, H. Schackert, A. Laner, 2017, Familial Cancer.

Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer

M. Kloor, M. Loeffler, J. Gebert, 2005, International journal of cancer.

Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

L. Vreede, C. Gilissen, R. Kuiper, 2016, PLoS genetics.

Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome

J. Rüschoff, H. Schackert, J. Plaschke, 2003, Journal of medical genetics.

A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.

C. Bloomfield, K. Grzeschik, T. Möröy, 2007, Blood.

with acute myeloid leukemia ) is associated GFI1 ( Growth Factor Independence 1 A variant allele of

K. Grzeschik, T. Möröy, M. Slovak, 2010 .

Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).

Dietmar Roesner, Andreas Ziegler, Inke R König, 2003, Human molecular genetics.

An intronic germline transition in the HNPCC gene hMSH2 is associated with sporadic colorectal cancer.

H. Schackert, H. Saeger, R. Koch, 1997, European journal of cancer.

The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC)

M. von Knebel Doeberitz, K. Schulmann, C. Engel, 2005, Journal of Medical Genetics.

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines

Susanne Seitz, Uwe Karsten, P. Schlag, 2003, Genes, chromosomes & cancer.

Loss of MSH3 Protein Expression Is Frequent in MLH1-Deficient Colorectal Cancer and Is Associated with Disease Progression 1

Stefan Krüger, Franz Theissig, Giancarlo Marra, 2004, Cancer Research.

Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

M. Kloor, K. Hemminki, A. Naccarati, 2010, BMC gastroenterology.

Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study.

Katherine M. Tucker, Aung Ko Win, Swati G. Patel, 2021, The Lancet. Oncology.

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Aung Ko Win, P. Møller, E. Hovig, 2019, Genetics in Medicine.

Accumulation of Genetic Alterations in Brain Metastases of Sporadic Breast Carcinomas Is Associated with Reduced Survival after Metastasis

G. Schackert, H. Schackert, H. Saeger, 1999, Invasion and Metastasis.

Role of germline aberrations affecting CTNNA1, MAP3K6 and MYD88 in gastric cancer susceptibility

A. Jakubowska, J. Lubiński, A. Wagner, 2018, Journal of Medical Genetics.

Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics

M. Kloor, M. von Knebel Doeberitz, H. Brenner, 2020, International journal of cancer.

Highly specific overexpression of the transcription factor SOX11 in human malignant gliomas.

Gabriele Schackert, E. Rieber, G. Schackert, 2005, Oncology reports.

Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.

M. von Knebel Doeberitz, M. Loeffler, J. Gebert, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC

M. Ebert, K. Schulmann, H. Schackert, 2008, European Journal of Human Genetics.

Construction of highly conductive nanowires on a DNA template

Wolfgang Pompe, Michael Mertig, Ingolf Mönch, 2001 .

Novel intronic polymorphisms in the RET proto‐oncogene and their association with Hirschsprung disease

Dietmar Roesner, Andreas Ziegler, Matthias Schreiber, 2003, Human mutation.

Association of RET protooncogene codon 45 polymorphism with Hirschsprung disease.

H. Schackert, E. Kuhlisch, G. Fitze, 1999, American journal of human genetics.

Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability.

H. Schackert, H. Saeger, J. Plaschke, 2003, Cancer letters.

Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy

S. Stevanović, E. Rieber, G. Schackert, 2007, British Journal of Cancer.

Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility.

Michael Krawczak, Henry Völzke, Barbara Burwinkel, 2010, Carcinogenesis.

Extended Single Nucleotide Polymorphism and Haplotype Analysis of the elastin Gene in Caucasians with Intracranial Aneurysms Provides Evidence for Racially/Ethnically Based Differences

I. König, A. Ziegler, G. Schackert, 2004, Cerebrovascular Diseases.

Within-gene interaction between c.135 G/A genotypes and RET proto-oncogene germline mutations in HSCR families.

H. Schackert, A. Serra, G. Fitze, 2003, European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

Germline truncating-mutations in BRCA1 and MSH6 in a patient with early onset endometrial cancer

E. Schröck, D. Aust, T. Neuhann, 2012, BMC Cancer.

The predictive role of delayed cutaneous hypersensitivity testing in postoperative complications.

C. Herfarth, H. Schackert, L. Edler, 1986, Surgery, gynecology & obstetrics.

The Role of Ret Genomic Variants in Infantile Hypertrophic Pyloric Stenosis

H. Schackert, J. Genuneit, H. Görgens, 2011, European Journal of Pediatric Surgery.

Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies

Johannes H. Hegemann, Christoph Engel, Robin Küppers, 2011, Familial Cancer.

Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1.

I. Fidler, H. Schackert, C. Seid, 1989, Cancer communications.

Tissue Inhibitor of Metalloproteinases-1, −2, and −3 Polymorphisms in a White Population With Intracranial Aneurysms

I. König, A. Ziegler, G. Schackert, 2003, Stroke.

Adjuvant chemotherapy (ACT) in stage II colon cancer (CC) in patients with Lynch syndrome.

K. Schulmann, W. Schmiegel, C. Engel, 2012 .

Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability

A. Ziegler, H. Schackert, J. Plaschke, 2012, International Journal of Colorectal Disease.

Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation

H. Schackert, F. Theissig, H. Saeger, 2002, International journal of cancer.

Clinical consequences of molecular diagnosis in families with mismatch repair gene germline mutations

H. Schackert, H. Saeger, J. Plaschke, 2000, International Journal of Colorectal Disease.

Preventive surgery for colon cancer in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer syndrome

H. Schackert, H. Saeger, G. Möslein, 2003, Langenbeck's Archives of Surgery.

Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development

L. Kiemeney, H. Clevers, I. Nagtegaal, 2015, The Journal of pathology.

Comparative Study of Monocyte-Mediated Cytotoxicity and Biological Response Modifier-Mediated Cytotoxicity Against Malignant Human Brain Tumor Cells In Vitro

G. Schackert, H. Schackert, M. Kirsch, 1993 .

Multiple Intracerebral Haemangioblastomas in Identical Twins with von Hippel-Lindau Disease – a Clinical and Molecular Study

G. Schackert, H. Schackert, S. Sobottka, 1998, Acta Neurochirurgica.

BRAFmutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient’s age

M. Kloor, M. von Knebel Doeberitz, H. Brenner, 2019 .

Mlh1-deficient Colorectal Cancer and Is Associated with Loss of Msh3 Protein Expression Is Frequent in Cited Articles Citing Articles E-mail Alerts Loss of Msh3 Protein Expression Is Frequent in Mlh1-deficient Colorectal Cancer and Is Associated with Disease Progression 1

H. Schackert, F. Theissig, H. Saeger, 2004 .

Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers

J. Rüschoff, H. Schackert, R. Büttner, 2008, Virchows Archiv.

Matrix Metalloproteinase-9 Coding Sequence Single-nucleotide Polymorphisms in Caucasians with Intracranial Aneurysms

I. König, A. Ziegler, G. Schackert, 2004, Neurosurgery.

Monocyte- and Lymphocyte-Mediated Cytotoxicity After Gene Transfer and Expression of Human Interleukin-2 in a Human Glioblastoma Cell Line

C. Herfarth, A. Mehrabi, H. Schackert, 1994 .

The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.

M. von Knebel Doeberitz, C. Engel, H. Schackert, 2007, Cancer letters.

Genetic Analysis of a Multifocal Glioblastoma Multiforme: A Suitable Tool to Gain New Aspects in Glioma Development

G. Schackert, H. Schackert, D. Krex, 2003, Neurosurgery.

The additive effect of p 53 Arg 72 Pro and RNASEL Arg 462 Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH 2 or MLH 1

C. Engel, H. Schackert, S. Krüger, 2007 .

The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect

M. von Knebel Doeberitz, P. Møller, G. Capellá, 2019, Cancer Epidemiology, Biomarkers & Prevention.

Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6

M. Kerscher, H. Schackert, A. Laner, 2017, Familial Cancer.

Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer.

C. Engel, J. Rüschoff, H. Schackert, 2006, Cancer letters.

Contents Vol. 16, 2003

Cheryl C. H. Yang, A. Rahimi, I. König, 2003, Cerebrovascular Diseases.

Infrequent genetic alterations of the tumor suppressor gene PTEN/MMAC1 in squamous cell carcinoma of the oral cavity.

H. Schackert, G. Haroske, I. Wieland, 2002, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Molecular genetic basis of colorectal cancer susceptibility

H. Schackert, H. Saeger, M. Dunlop, 1996, British Journal of Surgery.

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early‐onset colorectal cancer

L. Vreede, A. V. van Kessel, R. Kuiper, 2016, Genes, chromosomes & cancer.

A novel MSH2 germline mutation in homozygous state in two brothers with colorectal cancers diagnosed at the age of 11 and 12 years

J. Rüschoff, H. Schackert, J. Epplen, 2006, American journal of medical genetics. Part A.

Identification of six novel MSH2 and MLH1 germline mutations in HNPCC

D. Aust, H. Schackert, F. Theissig, 2003, Human mutation.

Analysis of RET, ZEB2, EDN3 and GDNF Genomic Rearrangements in 80 Patients with Hirschsprung Disease (Using multiplex ligation‐dependent probe amplification)

A. Ziegler, H. Schackert, H. Görgens, 2009, Annals of human genetics.

Cytosine deaminase gene as a potential tool for the genetic therapy of colorectal cancer

U. Haberkorn, J. Gebert, C. Herfarth, 1996, Journal of surgical oncology.