C. Lau

发表

Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 1. Dose-response analysis.

T. Knudsen, J. A. Wubah, R. Setzer, 2001, Teratology.

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study

J. Corton, C. Lau, J. Peters, 2014, Critical reviews in toxicology.

Perfluoroalkyl acids: a review of monitoring and toxicological findings.

C. Lau, J. Seed, D. Lai, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Uptake of perfluoroalkyl acids into edible crops via land applied biosolids: field and greenhouse studies.

Andrea C. Blaine, C. Lau, M. Mills, 2013, Environmental science & technology.

Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation.

M. Stanton, C. Lau, J. M. Rogers, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Identification of Biomarkers of Exposure to FTOHs and PAPs in Humans Using a Targeted and Nontargeted Analysis Approach.

Michael D McClean, Thomas F Webster, C. Lau, 2016, Environmental science & technology.

Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity.

D. Dix, J. Corton, Hongzu Ren, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate.

David M. Reif, Nisha S. Sipes, R. Judson, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice.

J. Wambaugh, C. Lau, M. Strynar, 2020, Toxicology.

Gene Profiling in the Livers of Wild-type and PPARα-Null Mice Exposed to Perfluorooctanoic Acid

J. Corton, M. Rosen, C. Lau, 2008, Toxicologic pathology.

Teratogenic effects of nitrofen on cellular and functional maturation of the rat lung.

R. Kavlock, C. Lau, C. Langston, 1988, Toxicology and applied pharmacology.

Perfluorinated Compounds: An Overview

C. Lau, 2015 .

PFAA Days III meeting report and highlights.

C. Lau, A. Lindstrom, Toni Krasnic, 2012, Reproductive toxicology.

Biological modeling of 5-fluorouracil developmental toxicity.

R. Kavlock, R. Setzer, C. Lau, 1995, Toxicology.

Vitamin D in cutaneous carcinogenesis: part I.

C. Lau, M. Asgari, Jean Y. Tang, 2012, Journal of the American Academy of Dermatology.

Vitamin D in cutaneous carcinogenesis: part II.

C. Lau, M. Asgari, Jean Y. Tang, 2012, Journal of the American Academy of Dermatology.

Comparative Hepatic Effects of Perfluorooctanoic Acid and WY 14,643 in PPAR-α Knockout and Wild-type Mice

M. Rosen, C. Lau, D. Wolf, 2008, Toxicologic pathology.

Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

C. Lau, B. Abbott, C. Wolf, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life

C. Lau, S. Fenton, J. Stanko, 2009, Molecular and Cellular Endocrinology.

Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR alpha) in the mouse.

C. Lau, B. Abbott, C. Wolf, 2009, Reproductive toxicology.

Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha

C. Lau, B. Abbott, C. Wolf, 2010, PPAR research.

Perfluoroalkyl acids: recent research highlights.

C. Lau, 2012, Reproductive toxicology.

Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs): further investigation of C4-C12 compounds.

C. Lau, B. Abbott, C. Wolf, 2012, Reproductive toxicology.

Testing for departures from additivity in mixtures of perfluoroalkyl acids (PFAAs).

C. Gennings, C. Lau, B. Abbott, 2013, Toxicology.

Does exposure to perfluoroalkyl acids present a risk to human health?

J. Corton, M. Rosen, C. Lau, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Gene expression profiling in the lung and liver of PFOA-exposed mouse fetuses.

M. Rosen, C. Lau, C. Wood, 2007, Toxicology.

Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.

C. Lau, C. Wood, K. Tatum-Gibbs, 2012, Reproductive toxicology.

Peroxisome Proliferator-Activated Receptors Alpha, Beta, and Gamma mRNA and Protein Expression in Human Fetal Tissues

C. Lau, C. Wood, B. Abbott, 2010, PPAR research.

Perfluorinated chemicals 2008: PFAA Days II meeting report and highlights.

C. Lau, J. Seed, A. Lindstrom, 2009, Reproductive toxicology.

Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS).

John W. Froehlich, C. Lau, Ravinder J. Singh, 2007, Toxicology.

Toxicological evaluation of ammonium perfluorobutyrate in rats: twenty-eight-day and ninety-day oral gavage studies.

C. Lau, D. Ehresman, J. Butenhoff, 2012, Reproductive toxicology.

A resolution on folic acid fortification.

C. Lau, Mary Alice Smith, 2015, Birth defects research. Part A, Clinical and molecular teratology.

Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis.

J. Corton, C. Lau, C. Wood, 2017, Toxicology.

Perfluoroalkyl acids: recent activities and research progress.

C. Lau, 2009, Reproductive toxicology.

Glucocorticoid receptor regulation in the rat embryo: a potential site for developmental toxicity?

G. Held, C. Lau, C. Wood, 2000, Toxicology and applied pharmacology.

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.

J. Corton, M. Rosen, C. Lau, 2017, Toxicology.

Per‐ and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Carla A. Ng, A. Boobis, C. Lau, 2020, Environmental toxicology and chemistry.

PPARs and Xenobiotic-Induced Adverse Effects: Relevance to Human Health

J. Corton, C. Lau, B. Abbott, 2011, PPAR research.

Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes.

M. Rosen, C. Lau, C. Wood, 2013, Toxicology.

TOXICOLOGICAL HIGHLIGHT Intercellular Communication, Homeostasis, and Toxicology

J. Trosko, C. Lau, Wenyue Hu, 2002 .

Lack of evidence for intergenerational reproductive effects due to prenatal and postnatal undernutrition in the female CD-1 mouse.

E. S. Hunter, M. Rosen, C. Lau, 2003, Reproductive toxicology.

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

J. Corton, M. Rosen, Russell S. Thomas, 2015, PloS one.

Regular ArticleReproductive Development and Functions in the Rat after Repeated Maternal Deprivation Stress

C. Lau, G. Klinefelter, A. Cameron, 1996 .

Toxicogenomic Dissection of the Perﬂuorooctanoic Acid Transcript Proﬁle in Mouse Liver: Evidence for the Involvement of Nuclear Receptors PPAR a and CAR

J. Corton, Hongzu Ren, M. Rosen, 2008 .

Developmental toxicity of perfluorononanoic acid in mice.

M. Rosen, C. Lau, C. Wood, 2015, Reproductive toxicology.

Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms

M. Longnecker, J. Corton, G. Vega, 2021, Toxicology.

The developmental toxicity of perfluoroalkyl acids and their derivatives.

C. Lau, J. M. Rogers, J. Butenhoff, 2004, Toxicology and applied pharmacology.

Comparative pharmacokinetics of perfluorobutyrate in rats, mice, monkeys, and humans and relevance to human exposure via drinking water.

Yu-Mei Tan, Kaberi Das, Geary W Olsen, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action.

Melvin E Andersen, Jennifer Seed, Gerald L Kennedy, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Toward a biologically based dose-response model for developmental toxicity of 5-fluorouracil in the rat: acquisition of experimental data.

R. Kavlock, R. Setzer, C. Lau, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of 5-fluorouracil on embryonic rat palate in vitro: fusion in the absence of proliferation.

W. Setzer, R. Kavlock, C. Lau, 1993, Teratology.

Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.

R. Kavlock, R. Setzer, C. Lau, 1997, Toxicology and applied pharmacology.

Epigenetics and the Developmental Origins of Health and Disease

C. Lau, J. M. Rogers, R. Ellis-Hutchings, 2010 .

Effects of perfluorooctanoic acid exposure during pregnancy in the mouse.

C. Lau, J. M. Rogers, M. Strynar, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects

J. Corton, M. Rosen, C. Lau, 2010, PPAR research.

Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague-Dawley rats in vivo.

Wenyue Hu, Paul D Jones, John P Giesy, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat.

C. Lau, D. Wolf, J. M. Rogers, 2005, Birth defects research. Part B, Developmental and reproductive toxicology.

Embryonic and fetal programming of physiological disorders in adulthood.

C. Lau, J. M. Rogers, J. Rogers, 2004, Birth defects research. Part C, Embryo today : reviews.

Reproductive development and functions in the rat after repeated maternal deprivation stress.

C. Lau, G. Klinefelter, A. Cameron, 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.

C. Lau, S. Nakayama, B. Abbott, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Advancing the Understanding of Vitamin D Status in Post-Thyroidectomy Hypocalcemia

C. Lau, N. Bansal, M. Fariduddin, 2021, International journal of endocrinology.

Utility of the murine erythroleukemic cell (MELC) in assessing mechanisms of action of DNA-active developmental toxicants: application to 5-fluorouracil.

C. Lau, J. M. Rogers, R. Zucker, 1993, Teratology.

Fetal programming of adult disease: implications for prenatal care.

C. Lau, J. M. Rogers, M. Ross, 2011, Obstetrics and gynecology.

Toward a biologically based dose-response model for developmental toxicity of 5-fluorouracil in the rat: a mathematical construct.

R J Kavlock, R W Setzer, R. Kavlock, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Exposure-disease continuum for 2-chloro-2'-deoxyadenosine (2-CdA), a prototype teratogen: induction of lumbar hernia in the rat and species comparison for the teratogenic responses.

T. Knudsen, J. A. Wubah, R. Setzer, 2002, Teratology.

Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS).

John W. Froehlich, C. Lau, D. Ehresman, 2008, Toxicology.

Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations.

C. Lau, B. Barbee, J. M. Rogers, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Zürich Statement on Future Actions on Per- and Polyfluoroalkyl Substances (PFASs)

Tony Fletcher, Yali Shi, Zhanyun Wang, 2018, Environmental health perspectives.

Perfluoroalkyl acid distribution in various plant compartments of edible crops grown in biosolids-amended soils.

Lakhwinder S Hundal, Andrea C. Blaine, Kuldip Kumar, 2014, Environmental science & technology.

Prenatal window of susceptibility to perfluorooctane sulfonate-induced neonatal mortality in the Sprague-Dawley rat.

C. Lau, D. Wolf, J. M. Rogers, 2003, Birth defects research. Part B, Developmental and reproductive toxicology.

Prenatal alpha-difluoromethylornithine treatment: effects on postnatal renal growth and function in the rat.

B. Rehnberg, R. Kavlock, C. Lau, 1989, Teratology.

Perfluorinated compounds.

C. Lau, Christopher Lau, 2012, Experientia supplementum.

Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures.

A. Calafat, C. Lau, S. Fenton, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluating the additivity of perfluoroalkyl acids in binary combinations on peroxisome proliferator-activated receptor-α activation.

C. Lau, C. Rider, B. Abbott, 2014, Toxicology.

Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic acid.

M. Rosen, C. Lau, C. Wood, 2009, Reproductive toxicology.

Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression.

C. Lau, J. Butenhoff, K. Wallace, 2008, Toxicology.

Effects of perfluorobutyrate exposure during pregnancy in the mouse.

Yu-Mei Tan, C. Lau, C. Wood, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Modeling single and repeated dose pharmacokinetics of PFOA in mice.

J. Wambaugh, R. Setzer, C. Lau, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Modeling single and repeated dose pharmacokinetics of PFOA in mice

J. Wambaugh, R. Setzer, C. Lau, 2009 .

A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species

R. Judson, J. Wambaugh, C. Lau, 2023, Toxics.

Comparative pharmacokinetics of perfluorononanoic acid in rat and mouse.

John F Wambaugh, J. Wambaugh, C. Lau, 2011, Toxicology.

Development of glucocorticoid receptor regulation in the rat forebrain: Implications for adverse effects of glucocorticoids in preterm infants

C. Lau, C. Wood, T. Slotkin, 2008, Brain Research Bulletin.

Development of cholinergic neurons in rat brain regions: dose-dependent effects of propylthiouracil-induced hypothyroidism.

M. Stanton, C. Lau, P. Brodish, 1998, Neurotoxicology and teratology.

Altered health outcomes in adult offspring of Sprague Dawley and Wistar rats undernourished during early or late pregnancy.

C. Lau, J. M. Rogers, R. Zucker, 2010, Birth defects research. Part B, Developmental and reproductive toxicology.

Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.

J Christopher Corton, Beena Vallanat, J. Corton, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Perinatal exposure to polychlorinated biphenyls Aroclor 1016 or 1254 did not alter brain catecholamines nor delayed alternation performancein Long-Evans rats

M. Stanton, C. Lau, D. Ellis, 2001, Brain Research Bulletin.

Behavioral development following daily episodes of mother-infant separation in the rat.

M. Stanton, K. Crofton, C. Lau, 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Elevated blood pressure in offspring of rats exposed to diverse chemicals during pregnancy.

C. Lau, J. M. Rogers, R. Zucker, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice

J. Corton, C. Lau, U. Apte, 2023, bioRxiv.

Evaluation of biologically based dose-response modeling for developmental toxicity: a workshop report.

C. Kimmel, T. Knudsen, R. Kavlock, 2000, Regulatory toxicology and pharmacology : RTP.

Biologically based dose-response modeling in developmental toxicology: biochemical and cellular sequelae of 5-fluorouracil exposure in the developing rat.

R. Kavlock, R. Setzer, C. Lau, 1994, Toxicology and Applied Pharmacology.

Biologically based risk assessment models for developmental toxicity.

C Lau, R W Setzer, R. Setzer, 2000, Methods in molecular biology.

Glucocorticoid receptor expression during the development of the embryonic mouse secondary palate.

C. Lau, B. Abbott, Abbott Bd, 1994, Journal of craniofacial genetics and developmental biology.

Effects of prenatal nitrofen exposure on cardiac structure and function in the rat.

C. Lau, A. Cameron, K. Robinson, 1986, Toxicology and applied pharmacology.